0001062993-18-004065.txt : 20181012 0001062993-18-004065.hdr.sgml : 20181012 20181012163317 ACCESSION NUMBER: 0001062993-18-004065 CONFORMED SUBMISSION TYPE: 10-Q PUBLIC DOCUMENT COUNT: 73 CONFORMED PERIOD OF REPORT: 20180831 FILED AS OF DATE: 20181012 DATE AS OF CHANGE: 20181012 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Orgenesis Inc. CENTRAL INDEX KEY: 0001460602 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 980583166 STATE OF INCORPORATION: NV FISCAL YEAR END: 1130 FILING VALUES: FORM TYPE: 10-Q SEC ACT: 1934 Act SEC FILE NUMBER: 001-38416 FILM NUMBER: 181120576 BUSINESS ADDRESS: STREET 1: 20271 GOLDENROD LANE CITY: GERMANTOWN STATE: MD ZIP: 20876 BUSINESS PHONE: (480) 659-6404 MAIL ADDRESS: STREET 1: 20271 GOLDENROD LANE CITY: GERMANTOWN STATE: MD ZIP: 20876 FORMER COMPANY: FORMER CONFORMED NAME: Orgenesis, Inc. DATE OF NAME CHANGE: 20110902 FORMER COMPANY: FORMER CONFORMED NAME: Business Outsourcing Service, Inc. DATE OF NAME CHANGE: 20090401 10-Q 1 form10q.htm FORM 10-Q Orgenesis Inc.: Form 10-Q - Filed by newsfilecorp.com

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 10-Q

[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934

For the Quarterly Period Ended August 31, 2018

or

[   ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934

For the Transition Period from _________to _________

Commission file number: 000-54329

ORGENESIS INC.
(Exact name of registrant as specified in its charter)

Nevada 98-0583166
(State or other jurisdiction of incorporation or (I.R.S. Employer Identification No.)
 organization)  

20271 Goldenrod Lane
Germantown, MD 20876
(Address of principal executive offices) (zip code)

(480) 659-6404
(Registrant’s telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.
Yes [X]     No [   ]

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§ 232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).
Yes [X]      No [   ]

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

Large accelerated filer [   ] Accelerated filer  [   ]
Non-accelerated filer [   ] Smaller reporting company  [X]
(Do not check if a smaller reporting company) Emerging Growth Company  [   ]

1


If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. [   ]

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).
Yes [   ]     No [X].

As of October 12, 2018, there were 15,570,973 shares of registrant’s common stock outstanding.

2


ORGENESIS INC.
FORM 10-Q
FOR THE THREE AND NINE MONTHS ENDED AUGUST 31, 2018 AND 2017

TABLE OF CONTENTS

                                                                                                                                                                                                                                Page
     
PART I - FINANCIAL INFORMATION  
   
ITEM 1 Financial Statements (unaudited)  
     
  Condensed Consolidated Balance Sheets as of August 31, 2018 and November 30, 2017 4
     
Condensed Consolidated Statements of Comprehensive Loss for the Three and Nine Months Ended August 31, 2018 and 2017 6
     
Condensed Consolidated Statements of Changes in Equity for the Nine Months Ended August 31, 2018 and 2017 7
     
Condensed Consolidated Statements of Cash Flows for the Nine Months Ended August 31, 2018 and 2017 8
     
  Notes to Condensed Consolidated Financial Statements 9
     
ITEM 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations 28
     
ITEM 3. Quantitative and Qualitative Disclosures about Market Risk 41
     
ITEM 4. Controls and Procedures 42
     
PART II - OTHER INFORMATION  
   
ITEM 1. Legal Proceedings 43
     
ITEM 1A. Risk Factors 43
     
ITEM 2. Unregistered Sales of Equity Securities and Use of Proceeds 45
     
ITEM 3. Defaults Upon Senior Securities 45
     
ITEM 4. Mine Safety Disclosures 45
     
ITEM 5. Other Information 45
     
ITEM 6. Exhibits 47
     
SIGNATURES 48

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PART I – UNAUDITED FINANCIAL INFORMATION

ITEM 1. CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

ORGENESIS INC.
CONDENSED CONSOLIDATED BALANCE SHEETS
(U.S. Dollars in Thousands)
(Unaudited)

    August 31,     November 30,  
    2018     2017  
             
Assets            
CURRENT ASSETS:            
     Cash and cash equivalents $  16,741   $  3,519  
     Restricted Cash   396     -  
     Accounts receivable, net   4,154     1,336  
     Prepaid expenses and other receivables   1,437     841  
     Receivables from related party   -     691  
     Grants receivable   267     183  
     Inventory   1,659     725  
Total current assets   24,654     7,295  
             
NON-CURRENT ASSETS:            
     Bank deposits   91     -  
     Call option derivative   -     339  
     Investments in associates, net   -     1,321  
     Property and equipment, net   11,056     5,104  
     Intangible assets, net   17,576     15,051  
     Goodwill   15,632     10,684  
     Other assets   287     78  
Total non-current assets   44,642     32,577  
           
TOTAL ASSETS $ 69,296   $  39,872  

The accompanying notes are an integral part of these condensed consolidated financial statements.

4



ORGENESIS INC.
CONDENSED CONSOLIDATED BALANCE SHEETS (Cont’d)
(U.S. Dollars in Thousands)
(Unaudited)

    August 31,     November 30,  
    2018     2017  
             
Liabilities and equity            
CURRENT LIABILITIES:            
       Accounts payable $  2,962   $  3,914  
       Accrued expenses and other payables   811     1,435  
       Employees and related payables   2,312     2,961  
       Related parties   177     116  
       Advance payments on account of grant   2,619     1,719  
       Short-term loans and current maturities of long-term loans   661     378  
       Deferred income   4,863     3,611  
       Current maturities of convertible loans   358     2,780  
       Other   190     -  
TOTAL CURRENT LIABILITIES   14,953     16,914  
             
LONG-TERM LIABILITIES:            
       Loans payable $  1,800   $  2,118  
       Convertible loans   -     2,415  
       Retirement benefits obligation   430     6  
       Deferred taxes   2,979     690  
       Other   524     -  
TOTAL LONG-TERM LIABILITIES   5,733     5,229  
TOTAL LIABILITIES   20,686     22,143  
             
COMMITMENTS            
             
REDEEMABLE NON-CONTROLLING INTEREST   18,646     3,606  
             
EQUITY:            
Common stock of $0.0001 par value, 145,833,334 shares authorized,
          13,620,262 and 9,872,659 shares issued and outstanding as of August
          31, 2018 and November 30, 2017, respectively
  1     1  
             
       Additional paid-in capital   80,889     55,334  
       Receipts on account of shares to be allotted   5,490     1,483  
       Accumulated other comprehensive income   660     1,425  
       Accumulated deficit   (57,415 )   (44,120 )
Equity attributable to Orgenesis Inc.   29,625     14,123  
Non-controlling interests   339     -  
TOTAL EQUITY   29,964     14,123  
TOTAL LIABILITIES AND EQUITY $  69,296   $  39,872  

The accompanying notes are an integral part of these condensed consolidated financial statements.

5



ORGENESIS INC.
CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS
(U.S. Dollars in thousands, except share and loss per share amounts)
(Unaudited)

    Three Months Ended     Nine Months Ended  
    August 31,     August 31,     August 31,     August 31,  
    2018     2017     2018     2017  
REVENUES $  6,230   $  2,562   $  12,853   $  6,712  
COST OF REVENUES   3,381     1,867     7,220     4,900  
GROSS PROFIT   2,849     695     5,633     1,812  
                         
RESEARCH AND DEVELOPMENT EXPENSES, net   1,902     500     3,456     1,906  
AMORTIZATION OF INTANGIBLE ASSETS   505     423     1,386     1,201  
SELLING, GENERAL AND ADMINISTRATIVE EXPENSES   4,008     3,184     10,675     7,887  
OTHER INCOME, net   (2,921 )   -     (3,237 )   -  
OPERATING LOSS   645     3,412     6,647     9,182  
FINANCIAL EXPENSES (INCOME), net   1,070     (45 )   3,164     2,534  
SHARE IN LOSSES OF ASSOCIATED COMPANY   202     152     732     348  
LOSS BEFORE INCOME TAXES   1,917     3,519     10,543     12,064  
TAX EXPENSES   2,353     421     1,680     493  
NET LOSS $  4,270   $  3,940   $  12,223   $  12,557  
NET INCOME ATTRIBUTABLE TO NON-CONTROLLING INTERESTS (INCLUDING REDEEMABLE)   800     -     1,072     -  
NET LOSS ATTRIBUTABLE TO THE COMPANY $  5,070   $  3,940   $  13,295   $  12,557  
                         
LOSS PER SHARE:                        
       Basic $  (0.35 ) $  (0.38 ) $  (1.04 ) $  (1.32 )
       Diluted $  (0.35 ) $  (0.40 ) $  (1.04 ) $  (1.34 )
WEIGHTED AVERAGE NUMBER OF SHARES
     USED IN COMPUTATION OF BASIC AND
     DILUTED LOSS PER SHARE:
               
       Basic   14,355,430     10,279,180     12,774,802     9,477,211  
       Diluted   14,355,430     10,385,499     12,774,802     9,503,253  
                         
OTHER COMPREHENSIVE LOSS:                        
   Net Loss $  4,270   $  3,940   $  12,223   $  12,557  
   Other Comprehensive (income) loss – Translation adjustment   416     (1,430 )   765     (2,419 )
   Comprehensive loss   4,686     2,510     12,988     10,138  
   Net income attributed to non-controlling interests (including redeemable)   800         1,072      
COMPREHENSIVE LOSS ATTRIBUTED TO ORGENESIS INC. $  5,486   $  2,510   $  14,060   $  10,138  

The accompanying notes are an integral part of these condensed consolidated financial statements.

6



ORGENESIS INC.
CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY
(U.S. Dollars in thousands, except share amounts)
(Unaudited)

    Common Stock                                            
                                                       
                                                       
                      Receipts on     Accumulated                          
                Additional     Account of     Other           Equity     Non-        
          Par     Paid-in     Share to be     Comprehensive     Accumulated     Attributable to     Controlling        
    Number     Value     Capital     Allotted     Loss     Deficit     Orgenesis Inc.     Interest     Total  
Balance at December 1, 2016   9,508,068   $  1   $  45,454   $  -   $  (1,205 ) $  (31,753 ) $  12,497   $  -   $  12,497  
Changes during the nine months ended August 31, 2017:                                                      
     Stock-based compensation to employees and directors               1,156                       1,156           1,156  
     Stock-based compensation to service providers   79,167     *     1,824                       1,824           1,824  
     Issuance of warrants and beneficial conversion feature of convertible loans               2,550                       2,550           2,550  
     Issuance of shares and receipts on account of shares and warrants to be allotted and cancelation of contingent shares   244,743     *     3,383     852             4,235         4,235  
     Comprehensive income (loss) for the period                           2,419     (12,557 )   (10,138 )         (10,138 )
Balance at August 31, 2017   9,831,978   $  1   $  54,367   $  852   $  1,214   $  (44,310 ) $  12,124   $  -   $  12,124  
                                                       
Balance at December 1, 2017   9,872,659     1     55,334     1,483     1,425     (44,120 )   14,123     -     14,123  
Changes during the nine months ended August 31, 2018:                                                      
     Stock-based compensation to employees and directors               1,416                       1,416           1,416  
     Stock-based compensation to service providers and restricted shares granted to service providers   195,000     *     1,568                 1,568         1,568  
     Issuance of warrants and beneficial conversion feature of convertible loans   1,341,134     *     7,330                       7,330           7,330  
     Issuance of shares and receipts on account of shares to be allotted related to acquisition of Atvio and CureCell   83,965     *     600     1,853             2,453     300     2,753  
     Issuance of shares and receipts on account of shares to be allotted   1,990,858     *     13,466     2,154                 15,620           15,620  
     Beneficial conversion feature of convertible loans and warrants issued               323                       323           323  
     Issuance of shares due to exercise of warrants   136,646     *     852                       852           852  
     Comprehensive income (loss) for the period                           (765 )   (13,295 )   (14,060 )   39     (14,021 )
     Balance at August 31, 2018   13,620,262   $  1   $  80,889   $  5,490   $  660   $  (57,415 ) $  29,625   $  339   $  29,964  

* represent an amount lower than $ 1 thousand

The accompanying notes are an integral part of these condensed consolidated financial statements.

7



ORGENESIS INC.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(U.S. Dollars in thousands)
(Unaudited)

    Nine Months Ended  
    August 31,     August 31,  
    2018     2017  
CASH FLOWS FROM OPERATING ACTIVITIES:            
     Net loss $  (12,223 ) $  (12,557 )
     Adjustments required to reconcile net loss to net cash used in operating activities:            
     Stock-based compensation   2,984     2,817  
     Share in losses of associated company   732     348  
     Depreciation and amortization expenses   1,833     1,874  
     Net gain on remeasurement of previously equity interest in Atvio and CureCell to acquisition date fair value   (4,509 )   -  
     Change in fair value of warrants and embedded derivatives   11     (230 )
     Change in fair value of convertible bonds   -     (157 )
     Interest expenses accrued on loans and convertible loans (including amortization of beneficial conversion feature)   2,856     818  
   Changes in operating assets and liabilities, net of business combination:            
       Increase in accounts receivable   (2,818 )   (682 )
       Decrease in related parties, net   (379 )   -  
       Increase in inventory   (848 )   (484 )
       Increase (decrease) in other assets   65     (1 )
       Increase in prepaid expenses and other accounts receivable   (148 )   (818 )
       Decrease in accounts payable   (1,723 )   (1,230 )
       Increase (decrease) in accrued expenses and other payables   (686 )   192  
       Increase (decrease) in employee and related payables   (820 )   554  
       Increase in deferred income   705     3,268  
       Increase in advance payments and receivables on account of grant, net   815     2,358  
       Increase in deferred taxes   1,680     494  
             Net cash used in operating activities   (12,473 )   (3,436 )
CASH FLOWS FROM INVESTING ACTIVITIES:            
   Purchase of property and equipment   (4,430 )   (639 )
   Disposals of property and equipment   -     31  
   Acquisition of CureCell , net of cash acquired (See note 4)   58     -  
   Acquisition of Atvio , net of cash acquired (See note 4)   245     -  
   Investments in long term deposit   (92 )   -  
   Investments in associate   -     (835 )
           Net cash used in investing activities   (4,219 )   (1,443 )
CASH FLOWS FROM FINANCING ACTIVITIES:            
     Short-term line of credit   -     (21 )
     Proceeds from issuance of shares and warrants (net of transaction costs)   12,666     4,307  
     Proceeds from issuance of convertible loans (net of transaction costs)   720     4,932  
     Repayment of convertible loans and convertible bonds   (177 )   (3,766 )
     Proceeds from receipts on account of shares to be allotted   3,626     -  
     Increase in redeemable non-controlling interests   14,007     -  
     Repayment of short and long-term debt   (331 )   (1,102 )
          Net cash provided by financing activities   30,511     4,350  
NET CHANGE IN CASH AND CASH EQUIVALENTS   13,819     (529 )
EFFECT OF EXCHANGE RATE CHANGES ON CASH AND CASH EQUIVALENTS   (201 )   400  
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD   3,519     891  
             
CASH AND CASH EQUIVALENTS AT END OF PERIOD $  17,137   $  762  
             
             
SUPPLEMENTAL NON-CASH FINANCING ACTIVITIES            
             
Conversion of loans and bonds (including accrued interest) to common stock and warrants $  7,511   $  106  
             
Classification of loan receivable into services to be received from CureCell $  813   $  -  

The accompanying notes are an integral part of these condensed consolidated financial statements.

8



ORGENESIS INC.
NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
For the Three and Nine Months Ended August 31, 2018 and 2017

NOTE 1 - GENERAL AND BASIS OF PRESENTATION

a.

General

Orgenesis Inc., a Nevada corporation (“Orgenesis” or the “Company”), is a service and research company in the field of the regenerative medicine industry with a focus on cell therapy development and manufacturing for advanced medicinal products. In addition, the Company is focused on developing novel and proprietary cell therapy trans-differentiation technologies for the treatment of diabetes. The consolidated financial statements include the accounts of Orgenesis Inc. and its subsidiaries, including those of the Masthercell Global group, a contract development and manufacturing organization, or CDMO, specializing in cell therapy development and manufacturing for advanced medicinal products in the USA, Belgium, Korea and Israel (See Note 4 for explanation that during the third fiscal quarter that the Company gained control of Atvio and CureCell); Orgenesis SPRL (the “Belgian Subsidiary”), a Belgian-based subsidiary which is engaged in development and manufacturing activities together with clinical development studies in Europe; Orgenesis Maryland Inc. (the “U.S. Subsidiary”), a Maryland corporation; and Orgenesis Ltd., an Israeli corporation, (the “Israeli Subsidiary”).

The Company’s goal is to industrialize cell therapy for fast, safe and cost-effective production in order to provide rapid therapies for any market around the world through a world-wide network of CDMO joint venture partners. The Company’s trans-differentiation technologies for treating diabetes, which will be referred to as the cellular therapy (“CT”) business, is based on a technology licensed by Tel Hashomer Medical Research (“THM”) to the Israeli Subsidiary that demonstrates the capacity to induce a shift in the developmental fate of cells from the liver and trans-differentiating (converting) them into “pancreatic beta cell-like” insulin-producing cells.

As used in this report and unless otherwise indicated, the term “Company” refers to Orgenesis Inc. and its subsidiaries (“Subsidiaries”). Unless otherwise specified, all amounts are expressed in United States Dollars.

On November 16, 2017, the Company implemented a reverse stock split of its outstanding shares of common stock at a ratio of 1-for-12 shares. The reverse stock split has been reflected in these condensed consolidated financial statements.

On March 13, 2018, the Company's common stock began to be listed and traded on the Nasdaq Capital Market under the symbol “ORGS.”

Consolidation of CDMO Entities and Strategic Funding

On June 28, 2018, the Company, Masthercell Global Inc. (a newly formed Delaware subsidiary of Orgenesis Inc being the Company that holds the Company’s CDMO business (“Masthercell Global”)), Great Point Partners, LLC, a manager of private equity funds focused on growing small to medium sized heath care companies (“Great Point”), and certain of Great Point’s affiliates, entered into a series of definitive strategic agreements intended to finance, strengthen and expand Orgenesis’ CDMO business. In connection therewith, the Company, Masthercell Global and GPP-II Masthercell, LLC, a Delaware limited liability company (“GPP-II”) and an affiliate of Great Point entered into Stock Purchase agreement (the “SPA”) pursuant to which GPP-II purchased 378,000 shares of newly designated Series A Preferred Stock of Masthercell Global (the “Masthercell Global Preferred Stock”), representing 37.8% of the issued and outstanding share capital of Masthercell Global, for cash consideration to be paid into Masthercell Global of up to $25 million, of which $13.2 million is subject to certain contingencies described below (the “Consideration”). Orgenesis holds 622,000 shares of Masthercell Global’s Common Stock, representing 62.2% of the issued and outstanding equity share capital of Masthercell Global. An initial cash payment of $11.8 million of the Consideration was remitted at closing by GPP-II to Masthercell Global. $1.5 Million of the initial capital contributed to Masthercell Global was used to reimburse the Investors for their fees and expenses incurred in conjunction with this transaction. The $1.5 million will reflect the entire fee payable under this transaction (net payment of $10.3 million). The follow up payment will be in the amount of $6,600,000 to be made in each of years 2018 and 2019 (the “Future Payments”), or an aggregate of $13.2 million, if (a) Masthercell Global achieves specified EBITDA and revenues targets during each of these years, and (b) the Orgenesis’ shareholders approve on or before December 31, 2019 certain provisions of the Stockholders’ Agreement entered into by these parties. None of the future Consideration amounts, if any, will result in an increase in GPP-II’s equity holdings in Masthercell Global beyond the 378,000 shares of Series A Preferred Stock issued to GPP-II at closing. Notwithstanding the foregoing, GPP-II may, in its sole discretion, elect to pay all or a portion of the future Consideration amounts even if the financial targets described above have not been achieved and the Orgenesis Stockholder Approval has not been obtained.

9


In connection with the entry into the SPA described above, each of the Company, Masthercell Global and GPP-II entered into the Masthercell Global Inc. Stockholders’ Agreement (the “Stockholders’ Agreement”) providing for certain restrictions on the disposition of Masthercell Global securities, the provisions of certain options and rights with respect to the management and operations of Masthercell Global, certain rights to GPP-II (including, without limitation, a tag along right, drag along right and certain protective provisions). After the earlier of the second anniversary of the closing or certain enumerated circumstances, GPP-II is entitled to effectuate a spinoff of Masthercell Global and the Masthercell Global Subsidiaries (the “Spinoff”). The Spinoff is required to reflect a market value determined by one of the top ten independent accounting firms in the U.S. selected by GPP, provided that under certain conditions, such market valuation shall reflect a valuation of Masthercell Global and the Masthercell Global Subsidiaries of at least $50 million. In addition, upon certain enumerated events described below, GPP-II is entitled, at its option, to put to the Company (or, at Company’s discretion, to Masthercell Global if Masthercell Global shall then have the funds available to consummate the transaction) its shares in Masthercell Global or, alternatively, purchase from the Company its share capital in Masthercell Global at a purchase price equal to the fair market value of such equity holdings provided that the purchase price shall not be greater than three times the price per share of Masthercell Global Preferred Stock paid by GPP-II and shall not be less than the price per share of Masthercell Global Preferred Stock paid by GPP-II. GPP-II may exercise its put or call option upon the occurrence of any of the following: (i) there is an Activist Shareholder of the Company; (ii) the Chief Executive Officer and/or Chairman of the board of directors of the Company resigns or is replaced, removed, or terminated for any reason prior to June 28, 2023; (iii) there is a Change of Control event of the Company; or (iv) the industry expert director appointed to the board of directors of Masthercell Global is removed or replaced (or a new such director is appointed) without the prior written consent of GPP-II. For the purposes of the foregoing, the following definitions shall apply: (A) “Activist Shareholder” shall mean any Person who acquires shares of capital stock of the Company who either: (x) acquires more than a majority of the voting power of the Company, (y) actively takes over and controls a majority of the board of directors of the Company, or (z) is required to file a Schedule 13D with respect to such Person’s ownership of the Company and has described a plan, proposal or intent to take action with respect to exerting significant pressure on the management of or directors of, the Company; and (B) “Change of Control” shall mean any of: (a) the acquisition, directly or indirectly (in a single transaction or a series of related transactions) by a Person or group of Persons of either (I) a majority of the common stock of the Company (whether by merger, consolidation, stock purchase, tender offer, reorganization, recapitalization or otherwise), or (II) all or substantially all of the assets of the Company and its Subsidiaries (but only if such transaction includes the transfer of Securities held by the Company), (b) if any four (4) of the directors of the Company as of June 28, 2018 are removed or replaced or for any other reason cease to serve as directors of the Company, (c) the filing of a petition in bankruptcy or the commencement of any proceedings under bankruptcy laws by or against the Company, provided that such filing or commencement shall be deemed a Change of Control immediately if filed or commenced by the Company or after sixty (60) days if such filing is initiated by a creditor of the Company and is not dismissed; (d) insolvency of the Company that is not cured by the Company within thirty (30) days; (e) the appointment of a receiver for the Company, provided that such appointment shall constitute an Change of Control immediately if the appointment was consented to by the Company or after sixty (60) days if not consented to by the Company and such appointment is not terminated; or (f) or dissolution of the Company.

The Stockholders’ Agreement further provides that GPP-II is entitled, at any time, to convert its share capital in Masthercell Global for the Company’s common stock in an amount equal to the lesser of (a)(i) the fair market value of GPP-II’s shares of Masthercell Global Preferred Stock to be exchanged, divided by (ii) the average closing price per share of Orgenesis Common Stock during the thirty (30) day period ending on the date that GPP-II provides the exchange notice (the “Exchange Price”) and (b)(i) the fair market value of GPP-II’s shares of Masthercell Global Preferred Stock to be exchanged assuming a value of Masthercell Global equal to three and a half (3.5) times the revenue of Masthercell Global during the last twelve (12) complete calendar months immediately prior to the exchange divided by (ii) the Exchange Price; provided, that in no event will (A) the Exchange Price be less than a price per share that would result in Orgenesis having an enterprise value of less than $250,000,000 and (B) the maximum number of shares of Orgenesis Common Stock to be issued shall not exceed 2,704,247 shares of outstanding Orgenesis Common Stock (representing approximately 19.99% of then outstanding Orgenesis Common Stock), unless Orgenesis obtains shareholder approval for the issuance of such greater amount of shares of Orgenesis Common Stock in accordance with the rules and regulations of the Nasdaq Stock Market.

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Great Point and Masthercell Global entered into an advisory services agreement pursuant to which Great Point is to provide management services to Masthercell Global for which Great Point will be compensated at an annual base compensation equal to the greater of (i) $250,000 per each 12 month period or (ii) 5% of the EBITDA for such 12 month period, payable in arrears in quarterly installments; provided, that these payments will (A) begin to accrue immediately, but shall not be paid in cash to Great Point until such time as Masthercell Global generates EBITDA of at least $2,000,000 for any 12 month period or the sale of or change in control of Masthercell Global, and (B) shall not exceed an aggregate annual amount of $500,000. Such compensation accrues but is not owed to Great Point until the earlier of (i) Masthercell Global generating EBITDA of at least $2 million for any 12 months period following the date of the agreement or (ii) a Sale of the Company or Change of Control of the Company (as both terms are defined therein).

GPP Securities, LLC, a Delaware limited liability company and an affiliate of Great Point and Masthercell Global entered into a transaction services agreement pursuant to which GPP Securities, LLC is to provide certain brokerage services to Masthercell Global for which GPP Securities LLC will be entitled to a certain Exit Fee and Transaction Fee (as both terms are defined in the agreement), such fees not to be less than 2 percent of the applicable transaction value.

The Company accounted for the investment made by GPP as a redeemable non-controlling interest due to the embedded redemption feature whose settlement is not at the Company discretion.

Corporate Reorganization

Contemporaneous with the execution of the SPA and the Stockholders’ Agreement, Orgenesis and Masthercell Global entered into a Contribution, Assignment and Assumption Agreement pursuant to which Orgenesis contributed to Masthercell Global assets relating to the CDMO Business (as defined below), including the CDMO subsidiaries (the “Corporate Reorganization”). For further details see Note 4. Together with MaSTherCell S.A., Atvio and CureCell are directly held subsidiaries under Masthercell Global (collectively, the “Masthercell Global Subsidiaries”).

Masthercell Global, through the Masthercell Global Subsidiaries, will be engaged in the business of providing manufacturing and development services to third parties related to cell therapy products, and the creation and development of technology, and optimizations in connection with such manufacturing and development services for third parties (the “CDMO Business”). Under the terms of the Stockholders’ Agreement, Orgenesis has agreed that so long as it owns equity in Masthercell Global and for two years thereafter it will not engage in the CDMO Business, except through Masthercell Global (but may continue to engage in its other areas of business). In addition, except for certain limited circumstances, each of Orgenesis and GPP-II agreed in the Stockholders’ Agreement to not recruit or solicit or hire any officer or employee of Masthercell Global that was or is involved in the CDMO Business.

b.

Liquidity

As of August 31, 2018, the Company accumulated losses of approximately $57.4 million. Although the Company is showing positive revenue and gross profit trends in its CDMO business, the Company expects to incur further losses in the CT business.

To date, the Company has been funding operations primarily from the proceeds from private placements of the Company’s convertible debt and equity securities and from revenues generated by MaSTherCell S.A. From December 1, 2017 through August 31, 2018, the Company received, through MaSTherCell S.A., proceeds of approximately $11.5 million in revenues and accounts receivable from customers, and $16.5 million from the private placement to accredited investors of the Company's equity and equity linked securities and convertible loans and exercise of warrants, out of which $8.1 million are from the institutional investor with whom the Company entered into definitive agreements in January 2017 for the private placement of units (see also Note 7(a)). In addition, from September 1, 2018 through October 12, 2018, the Company raised $3.4 million from the private placement referred to above of unsubscribed units under such investor’s subscription agreement, and proceeds of approximately $2.9 million in accounts receivable from customers of MaSTherCell S.A. See also Note 12.

11



c.

Basis of Presentation

These unaudited condensed consolidated financial statements of the Company have been prepared in accordance with U.S. GAAP, pursuant to the rules and regulations of the United States Securities and Exchange Commission (“SEC”) for interim financial statements. Accordingly, they do not contain all information and notes required by U.S. GAAP for annual financial statements. In the opinion of management, the unaudited condensed consolidated interim financial statements reflect all adjustments, which include normal recurring adjustments, necessary for a fair statement of the Company’s consolidated financial position as of August 31, 2018, and the consolidated statements of comprehensive loss for the three and nine months ended August 31, 2018 and 2017, and the changes in equity and cash flows for the nine-month period ended August 31, 2018 and 2017. The interim results are not necessarily indicative of the results to be expected for the year ending November 30, 2018. These unaudited interim condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and notes thereto included in the Company’s Annual Report on Form 10-K for the year ended November 30, 2017.

d.

Collaboration and Joint Venture Agreements

Mircod Limited

On June 19, 2018, the Company and Mircod Limited, a company formed under the laws of Cyprus (“Mircod”) entered into a Collaboration and License Agreement (the “Collaboration Agreement”) for the research, development and commercialization of potential key technologies related to biological sensing for the Company's clinical development and manufacturing projects (the “Development Project”). Within 45 days of the execution of the Collaboration Agreement, the parties are to approve a written project development plan outlining each party’s responsibilities with respect to the Development Project, and the Company will be funding the projected development costs as outlined in the development plan. Under the terms of the Collaboration Agreement, the Company remitted to Mircod an upfront payment of $50,000.

Under the Collaboration Agreement, all results of such collaboration (“Project Results”) shall be jointly owned by Mircod and the Company. The Company was granted an exclusive, worldwide sub licensable license under Mircod’s right in such Project Results to use and commercialize Project Results in consideration for a royalty of 5% of Net Sales (as defined in the Collaboration Agreement) of products incorporating Project Results.

Subject to completion of the Development Project, Mircod and the Company are to negotiate and enter into a manufacturing and supply agreement under which Mircod is to manufacture and supply products incorporating the Project Results and, at the Company’s request, to provide support and maintenance service for such products. If for whatever reason the parties fail to enter into such manufacturing and supply agreement within 90 days of the completion of the Development Project or if Mircod is unable to perform such services, the Company is entitled to manufacture the products, in which event Mircod will be entitled to a payment of $80,000 and royalties on Net Sales are to increase to 8% of Net Sales.

HekaBio K.K

On July 10, 2018, the Company and HekaBio K.K. (“HB”), a corporation organized under the laws of Japan entered into a Joint Venture Agreement (the “JVA”) pursuant to which the parties will collaborate in the clinical development and commercialization of regeneration and cell and gene therapeutic products (hereinafter the “Products”) in Japan (the “Project”). The parties intend to pursue the joint venture through a newly established Japanese company (hereinafter the “JV Company”) which the Company by itself, or together with a designee, will hold a 49% participating interest therein, with the remaining 51% participating interest being held by HB. HB will fund, at its sole expense, all costs associated with obtaining the requisite regulatory approvals for conducting clinical trials, as well as performing all clinical and other testing required for market authorization of the Products in Japan.

12


Under the JVA, each party may invest up to $10 million, which may take the form of a loan, if required, as determined by the steering committee. The terms of such investment, if any, will be on terms mutually agreeable to the parties, provided that the minimum pre-money valuation for any such investment shall not be less than $10 million. Additionally, HB was granted an option to affect an equity investment in the Company of up to $15 million within the next 12 months on mutually agreeable terms. If such investment is in fact consummated, the Company agreed to invest in the JV Company by way of a convertible loan an amount to HB’s pro-rata participating interest in the JV Company, which initially will be at 51%. Such loan may then be converted by the Company into share capital of the JV company at an agreed upon formula for determining JV Company valuation which in no event shall be less than $10 million. Under the JVA, the Company can require HB to sell to the Company its participating (including equity) interest in the JV Company in consideration for the issuance of the Company’s common stock based on an agreed upon formula for determining JV Company valuation which in no event shall be less than $10 million.

In addition, under the JVA, the Company shall grant the JV Company an exclusive license to certain intellectual property of the Company as may be required for the JV Company to develop and commercialize the Products in Japan. In consideration of such license, the JV Company shall pay the Company, in addition to other payments, royalties at the rate of 10% of the JV Company’s net sales of Products.

It was further agreed that the JV Company shall grant the Company (and its affiliates) a non-exclusive, worldwide (other than Japan), royalty-free and fully paid-up license to use and practice, for any purpose, new inventions, discoveries and intellectual property rights that are generated by and/or on behalf of HB and/or the JV Company in connection with the Project.

All matters pertaining to such license rights shall be governed under a separate license agreement to be entered by and between the Company and the JV Company.

As of August 31, 2018, no activity had begun in the said JV and no investments were made therein.

Image Securities Ltd.

On July 11, 2018, the Company and Image Securities Ltd., a corporation with its registered office in Grand Cayman, Grand Cayman Islands (“India Partner”) entered into a Joint Venture Agreement (the “India JVA”) pursuant to which the parties will collaborate in the development and/or marketing, clinical development and commercialization of cell therapy products in India (the “Cell Therapy Products”). The India Partner will collaborate with a network of healthcare facilities and a healthcare infrastructure as well as financial partners to advance the development and commercialization of the cell therapy products.

The India JVA becomes effective upon the consummation of an equity investment by the India partner in the Company of $5 million within 15 days of the execution of the India JVA through the purchase of units of Orgenesis securities at a per unit purchase price payable into the Company of $6.24, with each unit comprised of one share of the Company and three-year warrant for the acquisition of an additional common share at a per share exercise price of $6.24. Subject to the consummation of such equity investment in the Company, the Company is to advance to the JV Company a convertible loan in the amount of $5 million. The loan is convertible into equity capital of the JV Company at an agreed upon formula for determining JV Company valuation. The investment in the Company by the India Partner would be the consummation of the previously disclosed private placement subscription agreement entered into in December 2016 between the Company and an affiliate of the India Partner pursuant to which the closing of such subscription agreement was by the terms thereof delayed until terms comprising the India JV were mutually agreed to.

Under the India JVA, the India Partner agreed to invest in the JV $10 million within 12 months of the incorporation of the JV Company. If for whatever reason such investment is not made by the India Partner within such time, then Orgenesis is authorized to convert its above-referenced loan into 50% of the equity capital of the JV Company on a fully diluted basis, provided that if the pre-money valuation of the JV Company is then independently determined to be less than $5 million, then such conversion to be effected in the basis of such valuation.

13


As of August 31, 2018, no activity had begun in the said JV and no investments were made therein.

NOTE 2 - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

The accounting policies adopted are consistent with those of the previous financial year, except as noted below regarding the adoption of new accounting pronouncements.

Recently Issued Accounting Pronouncements- adopted by the Company

1)       In November 2016, the FASB issued ASU 2016-18, Statement of Cash Flows (Topic 230): Restricted Cash (a Consensus of the FASB Emerging Issues Task Force) (“ASU 2016-18”), which requires entities to include amounts generally described as restricted cash and restricted cash equivalents in cash and cash equivalents when reconciling beginning-of-period and end-of-period total amounts shown on the statement of cash flows. ASU 2016-18 is effective for annual reporting periods (including interim periods within those annual reporting periods) beginning after December 15, 2017. The Company adopted this standard as of beginning of 2018. The Company did not have restricted cash in the previously presented period. Therefore, there is no impact for the new adoption on previously reported periods.

2)       In July 2017, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) 2017-11, "Earnings Per Share (Topic 260); Distinguishing Liabilities from Equity (Topic 480; Derivatives and Hedging (Topic 815)", ("ASU 2017-11"). This update was issued to address complexities in accounting for certain equity-linked financial instruments containing down round features. The amendment changes the classification analysis of these financial instruments (or embedded features) so that equity classification is no longer precluded. The amendments in ASU 2017-11 are effective for annual reporting periods beginning after December 15, 2018, including interim reporting periods within those annual reporting periods. Early adoption is permitted. The Company elected to early adopt the standard effective September 1, 2017, retrospectively. Following is the result of the adoption on the Company’s condensed consolidated financial statements previously reported:

Shareholders’ Equity

    August 31, 2017  
          Impact        
    As reported     of        
    Previously     adoption     As revised  
    In thousands  
                   
Additional paid-in capital $  50,518   $  3,849   $  54,367  
Accumulated deficit $  (41,345 ) $  (2,965 ) $  (44,310 )
Total equity $  11,251   $  873   $  12,124  

Statement of Comp[rehensive Loss

    Nine months ended August 31, 2017     Three months ended August 31, 2017  
    As                 As              
    reported     Impact of     As     reported     Impact of     As  
    Previously     adoption     revised     Previously     adoption     revised  
    In thousands  
                                     
                                     
Financial expenses (income), net $  1,488   $  1,046   $  2,534   $  (2,032 ) $  1,987   $  (45 )
Loss before income taxes $  11,018   $  1,046   $  12,064   $  1,532   $  1,987   $  3,519  
Net loss $  11,511   $  1,046   $  12,557   $  1,953   $  1,987   $  3,940  

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NOTE 3 - SEGMENT INFORMATION

The Chief Executive Officer ("CEO") is the Company’s chief operating decision-maker ("CODM").

Based on the Company's organizational structure, its business activities and information reviewed by the CODM for the purposes of allocating resources and assessing performance, management has determined that there are two operating segments.

CDMO

The CDMO activity is comprised of a specialization in cell therapy development for advanced therapeutic products and is comprised of two types of services to its customers: (i) process and assay development services and (ii) cGMP contract manufacturing services. The CDMO activities include the operations of Masthercell Global since the Corporate Reorganization (which includes the operations of CureCell and Atvio from the same date) and MaSTherCell prior to the Corporate Reorganization. As of the date of acquisition of CureCell and Atvio their activity is included in this segment.

CT Business

The CT Business activity is based on our technology that demonstrates the capacity to induce a shift in the developmental fate of cells from the liver and differentiating (converting) them into “pancreatic beta cell-like” insulin producing cells for patients with Type 1 Diabetes. This segment is comprised of all entities aside from Masthercell Global, CureCell and Atvio.

The CODM does not review assets by segment, therefore the measure of assets has not been disclosed for each segment.

Segment data for the nine months ended August 31, 2018 is as follows:

                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Revenues from external customers $  15,807   $  83   $  (3,037 ) $  12,853*  
Cost of revenues   (7,826 )   -     927     (6,899 )
Segment gross profit (loss)   7,981     83     (2,110 )   5,954  
Research and development expenses, net   (245 )   (4,764 )   2,110     (2,899 )
Operating expenses   (3,895 )   (4,448 )         (8,343 )
Other income   228     -           228  
Segment operating profit (loss)   4,069     (9,129 )   -     (5,060 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
     Depreciation and amortization   (1,807 )   (7 )            
Segment performance   2,262     (9,136 )            

* The Company's revenues consist of: $9,493 from services and $3,360 from goods sold.

Reconciliation of segment performance to loss for the nine months ended August 31, 2018:

    Nine months  
    Ended August  
    31, 2018  
    in thousands  
Segment performance   (6,874 )
Stock-based compensation   (2,782 )
Financial expenses, net   (3,164 )
Net gain on remeasurement of previously
     equity interest in Atvio and CureCell to 
     acquisition date fair value
  4,509  
Transaction expenses related to GPP agreement   (1,500 )
Share in losses of associated companies   (732 )
Loss before income tax $  (10,543 )

15


Segment data for the three months ended August 31, 2018 is as follows:

                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Revenues from external customers $  8,092   $  83   $  (1,945 ) $  6,230*  
Cost of revenues   (3,908 )   -     539     (3,369 )
Segment gross profit (loss)   4,184     83     (1,406 )   2,861  
Research and development expenses, net   (245 )   (2,898 )   1,406     (1,737 )
Operating expenses   (1,712 )   (1,453 )         (3,165 )
Other expenses   (88 )   -           (88 )
Segment operating profit (loss)   2,139     (4,268 )   -     (2,129 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
     Depreciation and amortization   (567 )   (3 )            
Segment performance   1,572     (4,271 )            

* The Company's revenues consist of: $4,473 from services and $1,757 from goods sold.

Reconciliation of segment performance to loss for the three months ended August 31, 2018:

    Three Months  
    Ended August  
    31, 2018  
    in thousands  
 Segment performance   (2,699 )
Stock-based compensation   (955 )
Financial expenses, net   (1,070 )
Share in losses of associated companies   (202 )
Net gain on remeasurement of previously 
     equity interest in Atvio and CureCell to 
     acquisition date fair value
  4,509  
Transaction expenses related to GPP agreement   (1,500 )
Loss before income tax $  (1,917 )

Segment data for the nine months ended August 31, 2017 is as follows:

16



                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Revenues from external customers $  7,705   $  -   $  (993 ) $  6,712  
Cost of revenues   (4,358 )         403     (3,955 )
Segment gross profit (loss)   3,347           (590 )   2,757  
Research and development expenses, net         (1,932 )   590     (1,342 )
Operating expenses   (916 )   (6,060 )         (6,976 )
Segment operating profit (loss)   2,431     (7,992 )   -     (5,561 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
Depreciation and amortization expenses   (2,145 )   (7 )            
Segment Performance   286     (7,999 )            

Reconciliation of segment performance to loss for the nine months ended August 31, 2017:

    Nine Months  
    Ended  
    August 31,  
    2017  
    in thousands  
Segment performance   (7,713 )
Stock-based compensation   (1,469 )
Financial expenses, net   (2,534 )
Share in losses of associated companies   (348 )
Loss before income tax   (12,064 )

Segment data for the three months ended August 31, 2017 is as follows:

                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Net revenues from external customers $  2,956           (394 )   2,562  
Cost of revenues   (1,439 )         95     (1,344 )
Segment gross profit (loss)   1,517           (299 )   1,218  
Research and development expenses, net         (688 )   299     (389 )
Operating expenses   (1,641 )   (1,272 )         (2,913 )
Segment operating profit (loss)   (124 )   (1,960 )   -     (2,084 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
Depreciation and amortization expense   (945 )                  
Segment Performance   (1,069 )   (1,960 )            

Reconciliation of segment performance to loss for the three months ended August 31, 2017:

    Three  
    Months  
    Ended  
    August 31,  
    2017  
    in thousands  
Segment performance   (3,029 )
Stock-based compensation   (383 )
Financial expenses, net   45  
Share in losses of associated companies   (152 )
Loss before income tax   (3,519 )

17


Geographic, Product and Customer Information

Substantially all the Company's revenues and long-lived assets are in Belgium and South Korea. Net revenues from single customers from the CDMO segment that exceed 10% of total net revenues are:

    Nine Months Ended     Three Months Ended  
    August 31,     August 31,     August 31,     August 31,  
    2018     2017     2018     2017  
    (in thousands)  
Customer A $  2,339   $  852 $  -   $  2,813  
Customer B $  3,922   $  -   $  1,651   $  -  
Customer C $  3,109   $  809   $  956   $  1,904  
Customer D $  -   $  679   $  -   $  1,637  
Customer E $  -   $  -   $  1,100   $  -  
Customer F $  -   $  -   $  784   $  -  

NOTE 4 – EXERCISE OF CALL OPTIONS OF CURECELL AND ATVIO

Description of the Transactions

Contemporaneous with the execution of the SPA and the Masthercell Global Stockholders Agreement (as described above), the Company and Masthercell Global entered into a Contribution, Assignment and Assumption Agreement pursuant to which Company contributed to Masthercell Global the Orgenesis’ assets relating to the CDMO business, including the CDMO subsidiaries. In furtherance thereof, Masthercell Global, as Orgenesis’ assignee, acquired all of the issued and outstanding share capital of Atvio, the Company’s Israel based CDMO partner since August 2016, and 94.2% of the share capital of CureCell, the Company’s Korea based CDMO partner since March 2016. Orgenesis exercised the "call option" to which it was entitled under the joint venture agreements with each of these entities to purchase from the former shareholders their equity holding. The consideration for the outstanding share equity in each of Atvio and CureCell consisted solely of Company Common Stock. In respect of the acquisition of Atvio, the Company issued to the former Atvio shareholders an aggregate of 83,964 shares of Company Common Stock. In respect of the acquisition of CureCell, the Company will issue according to valuation to the former CureCell shareholders an aggregate of 202,846 shares of Company Common Stock. Together with MaSTherCell S.A., Atvio and CureCell are directly held subsidiaries under Masthercell Global.

CureCell and Atvio are customer-oriented CDMO companies specializing in cell therapy development for advanced medicinal products.

The exercise of the call options of CureCell and Atvio, pursuant to which the Company obtained effective control over such entities, was accounted for as a business combination. The results of operations of CureCell and Atvio have been included in the Company’s condensed consolidated statements of operations starting from June 28, 2018, the date on which the Company obtained effective control of CureCell and Atvio. The revenues from operations of CureCell and Atvio for the period from June 28, 2018, the acquisition date, to August 31, 2018 was approximately $784 thousands and $41 thousands, respectively.

Fair Value of Consideration Transferred

The Company accounted for the exercise of the call options of CureCell and Atvio as a business combination under the acquisition method of accounting.

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The following table summarizes the provisional allocation of purchase price to the fair values of the assets acquired and liabilities assumed as of the transaction date:

           CureCell      
           Total assets acquired:      
           Cash and cash equivalents $  58  
           Property and equipment, net   1,104  
           Inventory   148  
           Other assets   300  
           Other Intangible assets (a)   3,933  
           Goodwill (b)   3,950  
           Total assets   9,493  
       
Total liabilities assumed:      
           Deferred income from the company and others   1,945  
           Deferred tax   80  
           Fair value of convertible loan from the company   892  
           Non-controlling interests   299  
           Other liabilities   1,487  
Total liabilities   4,703  
Total consideration transferred $  4,790  
       
Fair value according of shares issued   1,853  
Acquisition date fair value of previously held equity interest   2,937  
Total consideration transferred $  4,790  

(a)       The allocation of the purchase price to the net assets acquired and liabilities assumed resulted in the recognition of other intangible assets which comprised of: Customer Relationships of $859 and “Know How” of $3,074. These other intangible assets have a useful life of 10 and 12 years, respectively. The useful life of the other intangible assets for amortization purposes was determined considering the period of expected cash flows generated by the assets used to measure the fair value of the intangible assets adjusted as appropriate for the entity-specific factors, including legal, regulatory, contractual, competitive, economic or other factors that may limit the useful life of intangible assets.

The fair value of the Know How was estimated using a relief of royalties’ approach. Under this method, the fair value of the Know How is equal to the royalty fee that the owner of the Know How could profit from if he was to license the Know How out.

Customer Relationships were estimated using a discounted cash flow method with the application of the multi-period excess earnings method. Under this method, an intangible asset’s fair value is equal to the present value of the incremental after-tax cash flows attributable only to the subject intangible asset after deducting contributory asset charges. An income and expenses forecast were built based upon specific intangible asset revenue and expense estimates.

(b)       The primary items that generate goodwill include the value of the synergies between the acquired company and the Company and the acquired assembled workforce, neither of which qualifies for recognition as an intangible asset.

Atvio

The total consideration of Atvio of $890 thousand was attributed mainly to goodwill.

The Company’s purchase price allocation for both companies are preliminary. The fair values of acquired assets and liabilities may be further adjusted as additional information becomes available during the measurement period. Additional information may become available subsequently and may result in changes in the values allocated to various assets and liabilities includes, but is not limited to, any changes in the values allocated to tangible and identified intangible assets acquired and liabilities assumed during the measurement period and may result in material adjustments to goodwill.

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NOTE 5 – CONVERTIBLE LOAN AGREEMENTS

(a)       During the nine months ended August 31, 2018, the Company entered into several unsecured convertible loan agreements with accredited or offshore investors for an aggregate amount of $720 thousand. The loans bear an annual interest rate of 6% and mature in six months or two years from the closing date, unless earlier converted subject to the terms defined in the agreements.

The loans provide that the entire principal amount and accrued interest convert into a Unit, consisting of one share of Common Stock and one three-year warrant exercisable into an additional share of common stock at a per share exercise price of $6.24. In addition, the Company issued to certain investors 40,064 three-year warrants to purchase up to an additional one share of the Company’s Common Stock at a per share exercise price of $6.24.

Since the closing price of the Company's publicly traded stock is greater than the effective conversion price on the closing date, the conversion feature is considered "beneficial" to the holders and equal to $193 thousand. The difference is treated as issued equity and reduces the carrying value of the host debt; the discount is accreted as deemed interest on the debt. The transaction costs for were approximately $89 thousand, out of which $31 thousand are stock-based compensation due to issuance of warrants (See also Note 8(c)). Through August 31, 2018, all convertible loans were converted. See additional information in Note 5b.

(b)       During the nine months ended August 31, 2018, holders of approximately $7.7 million in principal and accrued interest of convertible loans converted these outstanding amounts, into units of the Company’s securities at a deemed per unit conversion price of $6.24, with each unit comprised of: (i) one share of the Company’s Common Stock and (ii) one warrant, exercisable for a period of three years from the date of conversion, for an additional share of Common Stock, at a per share exercise price of $6.24. As a result of these conversions, the holders are entitled to 1,240,972 shares of Common Stock and three-year warrants for an additional 1,240,972 shares of common stock at a per share exercise price of $6.24.

The Company allocated the converted amounts based on the fair value of the warrants and the shares. The table below presents the converted amounts of the proceeds as of the closing date:

    Proceeds  
    allocation  
    (in thousands)  
Warrants component $  3,037  
Shares component   4,706  
Total $  7,743  

The fair value of these warrants determined using a Black-Scholes model based on the following assumptions:

  Nine Months Ended
  August 31, 2018
Value of one common share $7.61 - $13.85
Dividend yield 0%
Expected stock price volatility 94.12%-90.6%
Risk free interest rate 2.43%-2.29%
Expected term (years) 3

These loans had beneficial conversion features ("BCF"). Therefore, the Company recognized the unamortized BCF as of the conversion date as interest expenses.

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(c)       During the nine months ended August 31, 2018, holders of approximately $805 thousand in principal and accrued interest of a convertible loans outstanding from November 2014 and December 2016 converted their outstanding amounts, into shares of the Company’s common stock at a deemed conversion price of $4.80 and $6.24 per share. As a result of this conversion, the Company issued 137,765 shares of common stock.

These loans had beneficial conversion features ("BCF"). Therefore, the Company recognized the unamortized BCF as of the conversion date as interest expenses.

(d)       In March 2018, a former Israel-based consultant exercised warrants issued in November 2016 to purchase shares of the Company’s Common Stock. A related party of such consultant submitted at the same time notice of its intention to convert into shares of the Company’s common stock the principal amount and accrued interest of approximately $396 thousand outstanding under a loan originally advanced to the Company in November 2016. The exercise price of the warrants and conversion price were fixed at $0.52 per share (pre-reverse stock split implemented by the Company in November 2017). There is a significant disagreement between the Company and these two entities as to the number of shares of Common Stock issuable to these entities, and they contend that the number of shares of Common Stock issuable to them should not consider the reverse stock split. The Company rejects these contentions in their entirety and, based on the advice of specially retained counsel, believes that these claims are without legal merit and not made in good faith. The Company intends to vigorously defend its interests and pursue other avenues of legal address. Through its counsel, the Company has advised these entities that unless they withdraw their request within a specified period, the Company will cancel the above referenced agreements and these parties’ right to receive any shares of the Company’s Common Stock. In April 2018, the Company withdrew the agreements and deposited the principal amount and accrued interest of the loan in an escrow account presented as restricted cash in the balance sheet as of August 31, 2018.

NOTE 6 – COMMITMENTS

"MSA" with Adva Biotechnology Ltd.

On January 28, 2018, the Company and Adva Biotechnology Ltd. (“Adva”), entered into a Master Services Agreement (“MSA”), under which the Company and/or its affiliates are to provide certain services relating to development of products to Adva, as may be agreed between the parties from time to time. Under the MSA, the Company undertook to provide Adva with in kind funding in the form of materials and services having an aggregate value of $749,900 at the Company’s own cost in accordance with a project schedule and related mutually acceptable project budget. The Company entered into agreement with Atvio Biotech Ltd, its Israeli-based joint venture, to fulfill its obligations pursuant this MSA. As of August 31, 2018, the Company incurred a total expense of $282 thousand.

In consideration for and subject to the fulfillment by the Company of such in-kind funding commitment, Adva agreed that upon completion of the development of the products, the Company and/or its affiliates and Adva shall enter into a supply agreement pursuant to which for a period of eight (8) years following execution of such supply agreement, the Company and/or its affiliates (as applicable) is entitled (on a non-exclusive basis) to purchase the products from Adva at a specified discount pricing from their then standard pricing. The Company and/or its affiliates were also granted a non-exclusive worldwide right to distribute such products, directly or through any of their respective contract development and manufacturing organization (CDMO) service centers during such term. The MSA shall remain in effect for 10 years unless earlier terminated in accordance with its terms.

Grants

On December 18, 2017, MaSTherCell S.A. (“MaSTherCell”), as coordinator of the “Icone” project with a consortium of private and public searchers, received the approval of a new grant from the Walloon Region with a direct financial support of Euro 1 million ($1.2 million) in a program for development of iPS-derived Cortical Neurons. The program started in 2017 for a 4-year period until 2021. After two years, project partners will decide to continue the program upon pre-defined scientific milestone achievements. During the nine months ended August 31, 2018, MaSTherCell received an advance payment of Euro 0.6 million ($0.7 million).

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NOTE 7 – EQUITY

Financings

a)       In January 2017, the Company entered into definitive agreements with an institutional investor for the private placement of 2,564,115 units of the Company’s securities for aggregate subscription proceeds to the Company of $16 million at $6.24 price per unit. Each unit is comprised of one share of the Company’s Common Stock and a warrant, exercisable over a three-years period from the date of issuance, to purchase one additional share of Common Stock at a per share exercise price of $6.24. The subscription proceeds were payable on a periodic basis through September 2018. The Company subsequently agreed to delay the payments until October 15, 2018. Each periodic payment of subscription proceeds will be evidenced by the Company’s standard securities subscription agreement.

In July 2018, the Company entered into definitive agreements with assignees of the aforementioned institutional investor whereby these assignees remitted $4.6 million in respect of the units available under the original subscription agreement that have not been subscribed for, entitling such investors to 702,307 units, with each unit being comprised of (i) one share of the Company's common stock and (ii) one three-year warrant to purchase up to an additional one share of the Company’s common stock at a per share exercise price of $6.24.

During the nine months ended August 31, 2018 the investor and the assignees remitted to the Company $8,065 thousand, and the Company issued 1,263,204 shares of the Company’s Common Stock and three-year warrants to purchase up to an additional 1,263,204 shares of the Company’s Common Stock at a per share exercise price of $6.24.

The Company allocated the proceeds based on the fair value of the warrants and the shares. The table below presents the allocation of the proceeds as of the closing date:

    Proceeds  
    Allocation  
    (in thousands)  
Warrants component $  2,923  
Shares component   5,142  
Total $  8,065  

The fair value of these warrants determined using a Black-Scholes Model based on the following assumptions:

  Nine Months Ended
  August 31, 2018
   
Value of one common share $6.5-$14.68
Dividend yield 0%
Expected stock price volatility 90.6%-93.8%
Risk free interest rate 1.99%-2.73%
Expected term (years) 3

The transaction costs were approximately $328 thousand, out of which $121 thousand are stock-based compensation due to issuance of warrants and shares. See also 8(c).

As of August 31, 2018, the Company has received a total of $12.6 million out of the committed $16 million subscription proceeds.

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b)       During the nine months ended August 31, 2018, the Company entered into definitive agreements with accredited and other qualified investors relating to a private placement of 1,237,642 units. Each unit is comprised of (i) one share of the Company’s common stock and (ii) three-year warrant to purchase up to an additional one share of the Company’s Common Stock at a per share exercise price of $6.24, for aggregate proceeds to the Company of approximately $7.7 million.

The Company allocated the proceeds based on the fair value of the warrants and the shares. The table below presents the allocation of the proceeds as of the closing date:

    Proceeds  
    Allocation  
    (in thousands)  
Warrants component $  2,813  
Shares component   4,910  
Total $  7,723  

The transaction costs were approximately $349 thousand, out of which $125 thousand are stock-based compensation due to issuance of warrants. See also 8(c).

NOTE 8 – STOCK BASED COMPENSATION

a.

Options Granted to employees

Below is a table summarizing the terms of options granted to employees during the nine months ended August 31, 2018:

                      Fair Value at         
    No. of options     Exercise           grant     Expiration  
    granted     price     Vesting period     (in thousands)     period  
Employee   50,000   $ 4.42     Quarterly over a
period of 1 year
  $ 163     10 years  
Employees   30,500   $ 8.91     Quarterly over a
period of 2 years
  $ 192     10 years  
Employee   250,000   $ 8.36     Semi-annual over a
period of 1 year
  $ 1,488     10 years  
MaSTherCell's
employees
  70,300   $ 8.43     Quarterly over a
period of 2 years
  $ 464     10 years  
MaSTherCell's
employees
  123,550   $ 8.43     Quarterly over a
period of 4 years
  $ 925     10 years  

The fair value of these option grants is based on the following assumptions:

  Nine Months Ended
  August 31, 2018
Value of one common share $4.42 - $8.85
Dividend yield 0%
Expected stock price volatility 97%-91%
Risk free interest rate 2.96%-2.11%
Expected term (years) 5-7

b.

Options Granted to non-employees

Below is a table summarizing all the options granted to consultants and service providers during the nine months ended August 31, 2018:

                      Fair value at        
    No. of options     Exercise           grant     Expiration  
    granted     price     Vesting period     (in thousands)     period  
Non-employee   5,200     4.42     Over six months   $ 36     10 years  
Non-employee   13,725   $ 4.42,8.34     Immediately   $ 82     10 years  
Non-employee   8,333   $ 8.43     Annual over a period
of 5 year
  $ 57     10 years  

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The fair value of these option grants is based on the following assumptions:

  Nine Months Ended
  August 31, 2018
Value of one common share $8.3,$4.42
Dividend yield 0%
Expected stock price volatility 91%-98%
Risk free interest rate $2.33-$2.83
Expected term (years) 4.5-10

c.

Shares and Warrants Granted to non-employees

1)       During the nine months ended August 31, 2018, the Company granted to several consultants 50,938 warrants with each exercisable at $6.24 to $15.41 per share for three years as a success fee with respect to the issuance of the convertible loans and part of the private placement. The fair value of those warrants as of the date of grant using the Black-Scholes valuation model was $248 thousand.

2)       In December 2017, the Company entered into investor relations services, marketing and related services agreement. Under the terms of the agreement, the Company agreed to grant the consultant 100,000 shares of restricted common stock, out of which the first 25,000 shares will vest after 30 days from the signing date, and 75,000 shares are to vest monthly over 15 months commencing February 2018. As of August 31, 2018, 60,000 shares were vested. The fair value of the shares as of the date of grant was $738 thousand.

3)       In December 2017, the Company entered into an investor relations services, marketing and related services agreement. Under the terms of the agreement, the Company agreed to grant the consultant 95,000 shares of restricted common stock, of which the first 25,000 shares will vest after 30 days from the signing date, and 70,000 shares are to vest monthly over 14 months commencing February 2018. As of August 31, 2018, 60,000 shares were vested. The fair value of the shares as of the date of grant was $701 thousand.

4)       In January 2018, the Company entered into a consulting agreement with a financial advisor for a period of one year. Under the terms of the agreement, the consultant was entitled to receive $60 thousand and 19,000 units of the Company securities. Each unit is comprised of (i) one share of the Company’s common stock and (ii) a three-year warrant to purchase up to an additional one share of the Company’s Common Stock at a per share exercise price of $6.24. The fair value of the units as of the date of grant was $171 thousand, out of which $62 thousand reflect the fair value of the warrants using the Black-Scholes valuation model. In July 2018, the board approved an additional issuance of 6,629 shares and three-year warrants to purchase up to 6,629 shares of the Company’s Common Stock at a per share exercise price of $6.24. The fair value of the units as of the date of grant was $88 thousand.

5)       During the nine months ended August 31, 2018, investors exercised 136,646 warrants into 136,646 shares of the Company’s Common Stock, for aggregate proceeds of $853 thousand.

6)       On July 6, 2018, the Compensation Committee approved the issuance of 13,558 warrants to two consultants to purchase 13,558 shares of Common Stock, exercisable at a per share exercise price of $11.19.

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NOTE 9 – LOSS PER SHARE

The following table sets forth the calculation of basic and diluted loss per share for the period indicated:

    Three Months Ended     Nine Months Ended  
    August 31,     August 31,  
    2018     2017     2018     2017  
    (in thousands, except per share data)  
                         
Basic:                        
Loss for the period $  5,070   $  3,940   $  13,295   $  12,557  
   Weighted average number of common shares outstanding   14,355,430     10,279,180     12,774,802     9,477,211  
   Loss per common share $  (0.35 ) $  (0.38 ) $  (1.04 ) $  (1.32 )
Diluted:                        
Loss for the period $  5,070   $  3,940   $  13,295   $  12,557  
Changes in fair value of embedded
     derivative and interest expense on 
     convertible loans
  -     238     -     137  
Loss for the period $  5,070   $  4,178   $  13,295   $  12,694  
                         
Weighted average number of shares
     used in the computation of basic and diluted
     loss per share
  14,355,430     10,279,180     12,774,802     9,477,211  
Number of dilutive shares related to convertible loans   -     106,319     -     26,042  
Weighted average number of common shares outstanding   14,355,430     10,385,499     12,774,802     9,503,253  
                         
Loss per common share $  (0.35 ) $  (0.40 ) $  (1.04 ) $  (1.34 )

Diluted loss per share does not include 7,919,874 shares underlying outstanding options and warrants and 201,557 shares upon conversion of convertible notes for the nine months ended August 31, 2018, because the effect of their inclusion in the computation would be anti-dilutive.

Diluted loss per share does not include 4,375,856 shares underlying outstanding options and warrants and 2,462,598 shares upon conversion of convertible notes for the three and nine months ended August 31, 2017, because the effect of their inclusion in the computation would be anti-dilutive.

NOTE 10 - FAIR VALUE PRESENTATION

The Company measures fair value and discloses fair value measurements for financial assets and liabilities. Fair value is based on the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. The accounting standard establishes a fair value hierarchy that prioritizes observable and unobservable inputs used to measure fair value into three broad levels, which are described below:

Level 1: Quoted prices (unadjusted) in active markets that are accessible at the measurement date for assets or liabilities. The fair value hierarchy gives the highest priority to Level 1 inputs.
Level 2: Observable inputs that are based on inputs not quoted on active markets but corroborated by market data.
Level 3: Unobservable inputs are used when little or no market data is available. The fair value hierarchy gives the lowest priority to Level 3 inputs.
   
  In determining fair value, the Company utilizes valuation techniques that maximize the use of observable inputs and minimize the use of unobservable inputs, to the extent possible, and considers credit risk in its assessment of fair value.

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As of August 31, 2018, and November 30, 2017, the Company’s assets and liabilities that are measured at fair value and classified as level 3 fair value are as follows (in thousands):

    August 31,     November 30,  
    2018     2017  
    Level 3     Level 3  
Embedded derivatives convertible loans*(1) $  -   $  37  
Call/Put option derivatives $  -   $  (339 )

*

The embedded derivative is presented in the Company's balance sheets on a combined basis with the related host contract (the convertible loans).


  (1)

The fair value is determined by using a Black-Scholes Model.

The fair value of the convertible bonds is equal to their principal amount and the aggregate accrued interest.

The table below sets forth a summary of the changes in the fair value of the Company’s financial liabilities classified as Level 3 for the nine months ended August 31, 2018:

    Embedded     Put Option    
    Derivatives     Derivative    
             
Balance at beginning of the period $  37   $ (339 )
Repayment   (14 )   -  
Changes in fair value during the period   (23 )   49  
Option disposal (See Note 4)   -     290  
Balance at end of the period $  -   $  -  

(*) There were no transfers to Level 3 during the nine months ended August 31, 2018.

The table below sets forth a summary of the changes in the fair value of the Company’s financial assets and liabilities classified as Level 3 for the year ended November 30, 2017:

    Embedded     Convertible     Put Option  
    Derivatives     Bonds     Derivative  
                   
Balance at beginning of the year $  240   $  1,818   $  273  
Repayment   (876 )   (1,827 )      
Changes in fair value during the period   662     22     (612 )
Translation adjustments   11     (13 )      
Balance at end of the year $  37   $  -   $  (339 )

(*) There were no transfers to Level 3 during the twelve months ended November 30, 2017.

NOTE 11 – OTHER INCOME - NET

Includes net gain on remeasurement of previously equity interest in Atvio and CureCell to acquisition date fair value in the amount of $4,509 and transaction costs related to GPP agreement in the amount of $1.5 million.

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NOTE 12 - SUBSEQUENT EVENTS

In October 2018, the Company raised $3.4 million from the institutional investor referred to in Note 7 entitling such investor to 550,481 shares of Common Stock and three-year warrants for an additional 550,481 shares. Following this remittance and those referred to in Note 7, the Company has received, as of October 12, 2018, a total of $16 million out of the committed $16 million subscription proceeds under such agreement.

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ITEM 2. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Forward-Looking Statements

This Quarterly Report on Form 10-Q contains may contain forward-looking statements within the meaning of 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These statements are based upon beliefs of, and information currently available to, the Company’s management as well as estimates and assumptions made by Company’s management. Readers are cautioned not to place undue reliance on these forward-looking statements, which are only predictions and speak only as of the date hereof. When used herein, the words “anticipate,” “believe,” “estimate,” “expect,” “future,” “intend,” “plan,” or the negative of these terms and similar expressions as they relate to the Company or the Company’s management identify forward-looking statements. Such statements reflect the current view of the Company with respect to future events and are subject to risks, uncertainties, assumptions, and other factors, including the risks relating to the Company’s business, industry, and the Company’s operations and results of operations. Should one or more of these risks or uncertainties materialize, or should the underlying assumptions prove incorrect, actual results may differ significantly from those anticipated, believed, estimated, expected, intended, or planned.

Although the Company believes that the expectations reflected in the forward-looking statements are reasonable, the Company cannot guarantee future results, levels of activity, performance, or achievements. Except as required by applicable law, including the securities laws of the United States, the Company does not intend to update any of the forward-looking statements to conform these statements to actual results.

Our financial statements are prepared in accordance with accounting principles generally accepted in the United States (“GAAP”). These accounting principles require us to make certain estimates, judgments and assumptions. We believe that the estimates, judgments and assumptions upon which we rely are reasonable based upon information available to us at the time that these estimates, judgments and assumptions are made. These estimates, judgments and assumptions can affect the reported amounts of assets and liabilities as of the date of the financial statements as well as the reported amounts of revenues and expenses during the periods presented. Our financial statements would be affected to the extent there are material differences between these estimates and actual results. The following discussion should be read in conjunction with our financial statements and notes thereto appearing elsewhere in this report.

Unless otherwise indicated or the context requires otherwise, the words “we,” “us,” “our,” the “Company” or “our Company” or “Orgenesis” refer to Orgenesis Inc., a Nevada corporation, and its majority-owned subsidiary, Masthercell Global Inc., a Delaware corporation (“Masthercell Global”), and Orgenesis SPRL, a Belgian-based entity which is engaged in development and manufacturing activities, together with clinical development studies in Europe (the “Belgian Subsidiary), and its wholly-owned subsidiaries Orgenesis Ltd., an Israeli corporation (the “Israeli Subsidiary”), Orgenesis Maryland Inc., a Maryland corporation, and Cell Therapy Holdings S.A. Masthercell Global’s wholly-owned subsidiaries include MaSTherCell S.A (“MaSTherCell”), a Belgian-based subsidiary and a contract development and manufacturing organization, or CDMO, specialized in cell therapy development and manufacturing for advanced medicinal products; Atvio Biotech Ltd. (“Atvio”), an Israeli-based CDMO, and CureCell Co. Ltd. (“CureCell”), a Korea-based CDMO.

Corporate Overview

We are a vertically integrated service and research company in the regenerative medicine industry with a focus on cell and gene therapy development and manufacturing. Our Company operates through two platforms including (i) a Cell Therapy (“CT”) development platform and (ii) a Contract Development and Manufacturing Organization (“CDMO”) platform. Through our CT development platform, we are focused on the development of proprietary cell therapies, including our autologous trans-differentiation technology and therapeutic collaborations and licensing with other pre-clinical and clinical-stage biopharma companies and research and healthcare institutes. Through our CDMO platform, we are focused on manufacturing and development services for other biopharma companies.

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Activities in our CT platform include our Company’s trans-differentiation technology that demonstrates the capacity to induce a shift in the developmental fate of cells from the liver or other tissues and transdifferentiating them into “pancreatic beta cell-like” Autologous Insulin Producing (“AIP”) cells for patients with Type 1 Diabetes, acute pancreatitis and other insulin deficient diseases. This technology, which has yet to be proven in human clinical trials, has shown in relevant animal models that the human derived AIP cells produce insulin in a glucose-sensitive manner. This trans-differentiation technology is licensed by our Israeli Subsidiary and is based on the work of Prof. Sarah Ferber, our Chief Science Officer and a researcher at Tel Hashomer Medical Research Infrastructure and Services Ltd. (“THM”) in Israel. Our development plan calls for conducting additional pre-clinical safety and efficacy studies with respect to diabetes and other potential indications prior to initiating human clinical trials. Furthermore, through our CT platform, we are engaging in therapeutic collaborations and licensing with other academic centers and research centers in order to pursue emerging technologies of other cell therapy products in such areas as cell-based immunotherapies, cardiovascular diseases, neurodegenerative diseases and tissue regeneration. With respect to our trans-differentiation technology, we own or have exclusive rights to four (4) United States and seven (7) foreign issued patents, three (3) pending applications in the United States, eleven (11) pending applications in foreign jurisdictions, including Europe, Australia, Brazil, Canada, China, Eurasia, Israel, Japan, South Korea, Mexico, and Singapore, and one (1) international PCT patent application, relating to the trans-differentiation of cells (including hepatic cells) to cells having pancreatic β-cell phenotype and function, and their use in the treatment of degenerative pancreatic disorders including diabetes, pancreatic cancer, and pancreatitis.

Our CDMO platform operates through Masthercell Global, which currently consists of MaSTherCell in Belgium, Atvio in Israel and our subsidiaries in South Korea and in the United States, each having unique knowhow and expertise for manufacturing in a multitude of cell types. As part of our U.S. activity, we intend to also set up a CDMO facility in the United States. We believe that, in-order to provide the optimal service to our customers, we need to have a global presence. We target the international market as a key priority through our network of facilities that provide development, manufacturing and logistics services, utilizing our advanced quality management system and experienced staff. All these capabilities offered to third-parties are utilized for our internal development projects, with the goal of allowing us to be able to bring new products to patients faster and in a cost-effective way. Masthercell Global strives to provide services that are all compliant with GMP requirements, ensuring identity, purity, stability, potency and robustness of cell therapy products for clinical phase I, II, III and through commercialization.

Business Strategy

Our aim is to utilize our know-how and intellectual property in order to bring new autologous cell therapies to patients by leveraging and evolving our expertise toward point-of-care (“POCare”) cell therapies. We define POCare cell therapy as a process of collecting, processing and administering cells within the patient care setting, without the need to transfer the cells to be manufactured at a centralized facility. We believe the approach of decentralized manufacturing is an attractive proposition for personalized medicine because a POCare approach based on utilizing closed systems has the potential of reducing the required grade of clean room facilities, thus substantially reducing manufacturing costs. Furthermore, cell transportation, which is a high-risk and costly aspect of the supply chain, could be minimized or eliminated.

While our POCare strategy is currently limited to early stage development, we intend to continue developing a global POCare network, with the goal of developing autologous cell therapies with regional partners. We believe that we will reduce costs by leveraging our joint ventures with local partners who bring strong regional networks. Such networks include partnerships with local hospitals which allows us to engage in continuous in-licensing of autologous therapies from academia and research institutes, co-development of hospital and academic-based therapies, and utilization of hospital networks for clinical development of therapies.

We intend to leverage our following capabilities in order to advance our POCare strategy:

industrial manufacturing know-how and biological assay development;
integration of higher automation levels resulting in significantly lower cell production costs;
providing ingredients (assays, viruses, etc.) and technology components (e.g. sensors);
implementation of manufacturing automation enabling closed systems; and
a harmonized quality system.

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We operate our CDMO and the CT platforms as two separate business segments.

Revenue Model

Companies developing cell therapies need to decide early on in their approach to the transition from the lab to the clinic regarding the manufacturing and production of the cells necessary for their respective treatments. Of the companies active in this market, only a small number have established their own GMP manufacturing facilities due to the high costs and expertise required to develop and maintain such production centers. In addition to the limitations imposed by a limited number of trained personnel and high infrastructure/operational costs, we believe that the industry faces a need for custom innovative process development and manufacturing solutions. In this context, we have grown total revenue from $6.4 million in our fiscal year November 30, 2016 to $10.1 million for fiscal year November 30, 2017 and from $6.7 million for the nine months ended August 31, 2017 to $12.9 million for the nine months ended August 31, 2018. The increased revenues derive from an increase in the volume of the services provided by our CDMO segment, mainly from our Belgian-based subsidiary, MaSTherCell, through its customer service contracts with existing customers and the entry into new customer service contracts with leading biotech companies, as well as from revenues generated from existing manufacturing agreements.

Recent Significant Developments

Funding from SFPI

On November 15, 2017, we, MaSTherCell and the Belgian Sovereign Funds Société Fédérale de Participations et d'Investissement (“SFPI”) entered into a Subscription and Shareholders Agreement (the “Agreement”) pursuant to which SFPI completed an equity investment in MaSTherCell in the aggregate amount of €5million (approximately $5.9 million), for approximately 16.7% of MaSTherCell. Following the SFPI investment in MaSTherCell, in November 2017, MaSTherCell announced the expansion by 600m² of its facility in Belgium with a dedicated, late-stage clinical and commercial cGMP unit, anticipated to be operational by the fourth quarter of 2018. This new expansion enables MaSTherCell to augment its commercial capabilities in Europe with five state-of-the-art advanced manufacturing units and extended GMP-accredited quality control (QC) laboratories. On June 13, 2018, SPFI has paid into MaSTherCell S.A. the balance of Euro 1.9 million (approximately $2.3 million).

Collaboration Agreements/Joint Ventures

On June 19, 2018, we and Mircod Limited, a company formed under the laws of Cyprus (“Mircod”) entered into a Collaboration and License Agreement for the research, development and commercialization of potential key technologies related to biological sensing for our clinical development and manufacturing projects (the “Development Project”). Within 45 days of the execution of the Collaboration Agreement, the parties are to approve a written project development plan outlining each party’s responsibilities with respect to the Development Project, and we will be funding the projected development costs as outlined in the development plan. Under the terms of the Collaboration Agreement, we remitted to Mircod an upfront payment of $50,000.

On July 10, 2018, we and HekaBio K.K., a corporation organized under the laws of Japan (“HB”) entered into a Joint Venture Agreement (the “JVA”) pursuant to which the parties will collaborate in the clinical development and commercialization of regeneration and cell and gene therapeutic products (hereinafter the “Products”) in Japan (the “Project”). The parties intend to pursue the joint venture through a newly established Japanese company (hereinafter the “JV Company”) which the Company by itself, or together with a designee, will hold a 49% participating interest therein, with the remaining 51% participating interest being held by HB. HB will fund, at its sole expense, all costs associated with obtaining the requisite regulatory approvals for conducting clinical trials, as well as performing all clinical and other testing required for market authorization of the Products in Japan.

In addition, under the JVA, the Company shall grant the JV Company an exclusive license to certain intellectual property of the Company as may be required for the JV Company to develop and commercialize the Products in Japan. In consideration of such license, the JV Company shall pay the Company, in addition to other payments, royalties at the rate of 10% of the JV Company’s net sales of Products.

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It was further agreed that the JV Company shall grant the Company (and its affiliates) a non-exclusive, worldwide (other than Japan), royalty-free and fully paid-up license to use and practice, for any purpose, new inventions, discoveries and intellectual property rights that are generated by and/or on behalf of HB and/or the JV Company in connection with the Project.

All matters pertaining to such license rights shall be governed under a separate license agreement to be entered by and between the Company and the JV Company.

On July 11, 2018, we and Image Securities Ltd., a corporation with its registered office in Grand Cayman, Grand Cayman Islands (“India Partner”) entered into a Joint Venture Agreement (the “India JVA”) pursuant to which the parties will collaborate in the development and/or marketing, clinical development and commercialization of cell therapy products in India (the “Cell Therapy Products”). The India Partner will collaborate with a network of healthcare facilities and a healthcare infrastructure as well as financial partners to advance the development and commercialization of the cell therapy products.

The India JVA becomes effective upon the consummation of an equity investment by the India partner in the Company of $5 million through the purchase of units of Orgenesis securities at a per unit purchase price payable into the Company of $6.24, with each unit comprised of one share of Company common stock and three-year common stock purchase warrant for an additional share of common stock at a per share exercise price of $6.24.

On August 2, 2018, we entered into a research and license agreement (the “Research and License Agreement”) with B.G. Negev Technologies and Applications Ltd. and the National Institute for Biotechnology in the Negev Ltd., both affiliates of Ben-Gurion University of the Negev (both herein, the “BG Entitles”), pursuant to which, inter alia, we and the BG Entities agreed to collaborate in carrying out projects for the purpose of developing and commercializing a novel alginate scaffold technology for cell transplantation, with an initial focus on autoimmune diseases, as set forth under the Research and License Agreement (the “Projects”). Intellectual property rights created through the joint efforts us and the BG Entities under the Projects, in accordance with the terms set forth under the Research and License Agreement, shall be jointly owned by us and the BG Entities in equal (50%-50%) shares (the “Joint IP”). In addition, under the Research and License Agreement, the BG Entities granted the us an exclusive, worldwide, royalty-bearing license to make, develop and commercialize BG Entities’ rights in and to the BG Entities’ background intellectual property, the Project results, certain patents (as set forth under the Research and License Agreement) and the Joint IP, as well as products which are covered by any of the foregoing (“Licensed Products”), in the field of treatment of autoimmune diseases, including, use of islets to treat diabetes. In consideration of such license, we are required to pay the BG Entities, in addition to other payments, royalties at the rate of 4% of net sales actually received by us and/or any of our affiliates and sublicensees with respect to the commercialization of the Licensed Products, provided that such royalty rate shall be reduced to (i) 2.5%, in the event that the relevant Licensed Product is solely covered by or incorporates Joint IP (and not any other intellectual property rights), or (ii) 2%, in the event that the relevant Licensed Product is not covered by a valid claim under a patent or a pending patent application or not protected under any applicable statutory protections (as set forth under the Research and License Agreement). In addition to such royalty payments, we are also required to pay the BG Entities an amount equal to 15%-20% depending on the clinical trial stage, of income received by us from any sublicensee (which amount may be reduced in accordance with the terms and conditions set forth under the Research and License Agreement), milestone-related payments as well as an annual license fee in the amount of US$ 100,000.

Consolidation of CDMO Entities and Strategic Funding

On June 28, 2018, the Company, Masthercell Global Inc., a Delaware company and a newly formed subsidiary of the Company that holds our business relating to the third party contract manufacturing for cell therapy companies (CDMO) (“Masthercell Global”), Great Point Partners, LLC, a manager of private equity funds focused on growing small to medium sized heath care companies (“Great Point”), and certain of Great Point’s affiliates, entered into a series of definitive strategic agreements intended to finance, strengthen and expand Orgenesis’ CDMO business. In connection therewith, the Company, Masthercell Global and GPP-II Masthercell, LLC, a Delaware limited liability company (“GPP-II”) and an affiliate of Great Point entered into Stock Purchase agreement (the “SPA”) pursuant to which GPP-II purchased 378,000 shares of newly designated Series A Preferred Stock of Masthercell Global (the “Masthercell Global Preferred Stock”), representing 37.8% of the issued and outstanding share capital of Masthercell Global, for cash consideration to be paid into Masthercell Global of up to $25 million, subject to certain adjustments (the “Consideration”). Orgenesis holds 622,000 shares of Masthercell Global’s Common Stock, representing 62.2% of the issued and outstanding equity share capital of Masthercell Global. An initial cash payment of $11.8 million of the Consideration was remitted at closing, with a follow up payment of $6,600,000 to be made in each of years 2018 and 2019 (the “Future Payments”), or an aggregate of $13.2 million, if (a) Masthercell Global achieves specified EBITDA and revenues targets during each of these years, and (b) the Orgenesis’ shareholders approve certain provisions of the Stockholders’ Agreement referred to below on or before December 31, 2019. None of the future Consideration amounts, if any, will result in an increase in GPP-II’s equity holdings in Masthercell Global beyond the 378,000 shares of Series A Preferred Stock issued to GPP-II at closing. The proceeds of the investment will be used to fund the activities of Masthercell Global and its consolidated subsidiaries. Notwithstanding the foregoing, GPP-II may, in its sole discretion, elect to pay all or a portion of the future Consideration amounts even if the financial targets described above have not been achieved and the Orgenesis Stockholder Approval has not been obtained.

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In connection with the entry into the SPA described above, each of the Company, Masthercell Global and GPP-II entered into the Masthercell Global Inc. Stockholders’ Agreement (the “Stockholders’ Agreement”) providing for certain restrictions on the disposition of Masthercell Global securities, the provisions of certain options and rights with respect to the management and operations of Masthercell Global, certain favorable, preferential rights to GPP-II (including, without limitation, a tag right, drag right and certain protective provisions), a right to exchange the Masthercell Global Preferred Stock for shares of Orgenesis common stock and certain other rights and obligations. In addition, after the earlier of the second anniversary of the closing or certain enumerated circumstances, GPP-II is entitled to effectuate a spinoff of Masthercell Global and the Masthercell Global Subsidiaries (the “Spinoff”). The Spinoff is required to reflect a market value determined by one of the top ten independent accounting firms in the U.S. selected by GPP, provided that under certain conditions, such market valuation shall reflect a valuation of Masthercell Global and the Masthercell Global Subsidiaries of at least $50 million. In addition, upon certain enumerated events as described below, GPP-II is entitled, at its option, to put to the Company (or, at Company’s discretion, to Masthercell Global if Masthercell Global shall then have the funds available to consummate the transaction) its shares in Masthercell Global or, alternatively, purchase from the Company its share capital in Masthercell Global at a purchase price equal to the fair market value of such equity holdings as determined by one of the top ten independent accounting firms in the U.S. selected by GPP-II, provided that the purchase price shall not be greater than three times the price per share of Masthercell Global Preferred Stock paid by GPP-II and shall not be less than the price per share of Masthercell Global Preferred Stock paid by GPP-II . GPP-II may exercise its put or call option upon the occurrence of any of the following: (i) there is an Activist Shareholder of the Company; (ii) the Chief Executive Officer and/or Chairman of the board of directors of the Company resigns or is replaced, removed, or terminated for any reason prior to June 28, 2023; (iii) there is a Change of Control event of the Company; or (iv) the industry expert director appointed to the board of directors of Masthercell Global is removed or replaced (or a new such director is appointed) without the prior written consent of GPP-II. For the purposes of the foregoing, the following definitions shall apply: (A) “Activist Shareholder” shall mean any Person who acquires shares of capital stock of the Company who either: (x) acquires more than a majority of the voting power of the Company, (y) actively takes over and controls a majority of the board of directors of the Company, or (z) is required to file a Schedule 13D with respect to such Person’s ownership of the Company and has described a plan, proposal or intent to take action with respect to exerting significant pressure on the management of or directors of, the Company; and (B) “Change of Control” shall mean any of: (a) the acquisition, directly or indirectly (in a single transaction or a series of related transactions) by a Person or group of Persons of either (I) a majority of the common stock of the Company (whether by merger, consolidation, stock purchase, tender offer, reorganization, recapitalization or otherwise), or (II) all or substantially all of the assets of the Company and its Subsidiaries (but only if such transaction includes the transfer of Securities held by the Company), (b) if any four (4) of the directors of the Company as of June 28, 2018 are removed or replaced or for any other reason cease to serve as directors of the Company, (c) the filing of a petition in bankruptcy or the commencement of any proceedings under bankruptcy laws by or against the Company, provided that such filing or commencement shall be deemed a Change of Control immediately if filed or commenced by the Company or after sixty (60) days if such filing is initiated by a creditor of the Company and is not dismissed; (d) insolvency of the Company that is not cured by the Company within thirty (30) days; (e) the appointment of a receiver for the Company, provided that such appointment shall constitute an Change of Control immediately if the appointment was consented to by the Company or after sixty (60) days if not consented to by the Company and such appointment is not terminated; or (f) or dissolution of the Company .

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The Stockholders’ Agreement further provides that GPP-II is entitled, at any time, to convert its share capital in Masthercell Global for the Company’s common stock in an amount equal to the lesser of (a)(i) the fair market value of GPP-II’s shares of Masthercell Global Preferred Stock to be exchanged, as determined by one of the top ten independent accounting firms in the U.S. selected by GPP-II and the Company, divided by (ii) the average closing price per share of Orgenesis Common Stock during the thirty (30) day period ending on the date that GPP-II provides the exchange notice (the “Exchange Price”) and (b)(i) the fair market value of GPP-II’s shares of Masthercell Global Preferred Stock to be exchanged assuming a value of Masthercell Global equal to three and a half (3.5) times the revenue of Masthercell Global during the last twelve (12) complete calendar months immediately prior to the exchange divided by (ii) the Exchange Price; provided, that in no event will (A) the Exchange Price be less than a price per share that would result in Orgenesis having an enterprise value of less than $250,000,000 and (B) the maximum number of shares of Orgenesis Common Stock to be issued shall not exceed 2,704,247 shares of outstanding Orgenesis Common Stock (representing approximately 19.99% of then outstanding Orgenesis Common Stock), unless Orgenesis obtains shareholder approval for the issuance of such greater amount of shares of Orgenesis Common Stock in accordance with the rules and regulations of the Nasdaq Stock Market.

Great Point and Masthercell Global entered into an advisory services agreement pursuant to which Great Point is to provide management services to Masthercell Global for which Great Point will be compensated at an annual base compensation equal to the greater of (i) $250,000 per each 12 month period or (ii) 5% of the EBITDA for such 12 month period, payable in arrears in quarterly installments; provided, that these payments will (A) begin to accrue immediately, but shall not be paid in cash to Great Point until such time as Masthercell Global generates EBITDA of at least $2,000,000 for any 12 month period or the sale of or change in control of Masthercell Global, and (B) shall not exceed an aggregate annual amount of $500,000. Such compensation accrues but is not owed to Great Point until the earlier of (i) Masthercell Global generating EBITDA of at least $2 million for any 12 months period following the date of the agreement or (ii) a Sale of the Company or Change of Control of the Company (as both terms are defined therein).

GPP Securities, LLC, a Delaware limited liability company and an affiliate of Great Point and Masthercell Global entered into an transaction services agreement pursuant to which GPP Securities, LLC is to provide certain brokerage services to Masthercell Global for which GPP Securities LLC will be entitled to a certain Exit Fee and Transaction Fee (as both terms are defined in the agreement), such fees not to be less than 2 percent of the applicable transaction value.

Corporate Reorganization

Contemporaneous with the execution of the SPA and the Stockholders’ Agreement, Orgenesis and Masthercell Global entered into a Contribution, Assignment and Assumption Agreement pursuant to which Orgenesis contributed to Masthercell Global the Orgenesis’ assets relating to the CDMO Business (as defined below), including the CDMO subsidiaries (the “Corporate Reorganization”). In furtherance thereof, Masthercell Global, as Orgenesis’ assignee, acquired all of the issued and outstanding share capital of Atvio, the Company’s Israel based CDMO partner since May 2016, and 94.2% of the share capital of CureCell, the Company’s Korea based CDMO partner since March 2016. Orgenesis exercised the” call option” to which it was entitled under the joint venture agreements with each of these entities to purchase from the former shareholders their equity holding. The consideration for the outstanding share equity in each of Atvio and CureCell consisted solely of Orgenesis Common Stock. In respect of the acquisition of Atvio, Orgenesis Inc. issued to the former Atvio shareholders an aggregate of 84,085 shares of Orgenesis Common Stock. In respect of the acquisition of CureCell, Orgenesis Inc. issued to the former CureCell shareholders an aggregate of 202,846 shares of Orgenesis Common Stock subject to a third-party valuation. Together with MaSTherCell S.A., Atvio and CureCell are directly held subsidiaries under Masthercell Global (collectively, the “Masthercell Global Subsidiaries”).

Masthercell Global, through the Masthercell Global Subsidiaries, will be engaged in the business of providing manufacturing and development services to third parties related to cell therapy products, and the creation and development of technology, and optimizations in connection with such manufacturing and development services for third parties (the “CDMO Business”). Under the terms of the Stockholders’ Agreement, Orgenesis has agreed that so long as it owns equity in Masthercell Global and for two years thereafter it will not engage in the CDMO Business, except through Masthercell Global (but may continue to engage in its other areas of business). In addition, except for certain limited circumstances, each of Orgenesis and GPP-II agreed in the Stockholders’ Agreement to not recruit or solicit or hire any officer or employee of Masthercell Global that was or is involved in the CDMO Business.

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We intend, through our direct subsidiaries, to continue to engage in the manufacturing, researching, marketing, developing, selling and commercializing (either alone or jointly with third parties) products that are not directly related to the CDMO business, including, joint ventures, collaboration, partnership or similar arrangement with a third party.

Results of Operations

Comparison of the Three Months Ended August 31, 2018 to the Three Months Ended August 31, 2017

Our financial results for the three months ended August 31, 2018 are summarized as follows in comparison to the three months ended August 31, 2017:

    Three Months Ended August 31,  
    2018     2017  
    (in thousands)  
Revenues $  6,230   $  2,562  
Cost of sales   3,381     1,867  
Research and development expenses, net   1,902     500  
Amortization of intangible assets   505     423  
Selling, general and administrative expenses   4,008     3,184  
Other income   (2,921 )   -  
Share in losses of associated company   202     152  
Financial expense (income), net   1,070     (45 )
Loss before income taxes $  1,917   $  3,519  

Revenues

    Three Months Ended August 31,  
    2018     2017  
    (in thousands)  
Services $  4,473   $  2,015  
Goods   1,757     547  
Total $  6,230   $  2,562  

All of our revenues were derived from the CDMO segment, most of which were generated from our Belgian Subsidiary, MaSTherCell S.A. We believe that revenue diversification by source in the CDMO segment, together with a leading position in immunotherapy and, in particular, CAR T-cell therapy development and manufacturing, strengthen MaSTherCell’s resilience in the industry.

Our revenues for the three months ended August 31, 2018 were $6,230 thousand, as compared to $2,562 thousand for the corresponding period in 2017, representing an increase of 143%. The increase in revenues for the three months ended August 31, 2018 compared to the corresponding period in 2017 is attributable to an increase in the projects provided by MaSTherCell, resulting primarily from the extension of existing customer service contracts with biotechnology clients, as well as from revenues generated from existing manufacturing agreements.

In March 2018, MaSTherCell entered into an agreement with ZELLUNA Immunotherapy to develop and manufacture TCR adoptive cell therapy platform for which MaSTherCell has recognized revenue of approximately $515 thousand during the three months ended August 31, 2018.

In April 2018, MaSTherCell entered into an agreement with a U.S. customer to manufacture autologous TIL therapies for which MaSTherCell has recognized revenue of approximately $1.1 million during the three months ended August 31, 2018.

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In addition, we acquired all the issued and outstanding share capital of Atvio, our Israel based CDMO partner since August 2016, and 94.2% of the share capital of CureCell, our Korea based CDMO partner since March 2016, which are reflected in the increase in our revenues from services provided of $823 thousand during the three months ended August 31, 2018.

Expenses

Cost of Revenues

    Three Months Ended August 31,  
    2018     2017  
    (in thousands)  
Salaries and related expenses $  1,568   $  515  
Stock-based compensation   28     -  
Professional fees and consulting services   98     (90 )
Raw materials   1,504     832  
Depreciation and amortization expenses, net   (36 )   522  
Other expenses   219     88  
  $  3,381   $  1,867  

Cost of revenues for the three months ended August 31, 2018 were $3,381 thousand, as compared to $1,867 thousand, during the same period in 2017, representing an increase of 81%. The increase for the three months ended in August 31, 2018 as compared to the corresponding period in 2017 is primarily attributed to the following:

(i)

An increase of $672 thousand in raw materials due to the growth in the volume of the services provided by MaSTherCell, as well as from revenues generated from existing and new manufacturing agreements.

   
(ii)

An increase in salaries and related expenses primarily attributable to an increase of 79% in personnel in our production and development department. This increase is attributable to the increase of our operations.

   
(iii)

A decrease in the Depreciation and amortization expenses due to change in the amortization in 2018 due to the change in valuations' rules over property and equipment.

Research and Development Expenses

    Three Months Ended August 31,  
    2018     2017  
    (in thousands)  
Salaries and related expenses $  846   $  321  
Stock-based compensation   106     112  
Professional fees and consulting services   (167 )   (7 )
Lab expenses   1,063     329  
Depreciation expenses, net   82     -  
Other research and development expenses   138     14  
Less – grant   (166 )   (269 )
Total $  1,902   $  500  

Research and development expenses for the three months ended August 31, 2018 were $1,902 thousand, as compared to $500 thousand for the same period in 2017, representing an increase of 280%. The increase in research and development expenses in the three months ended August 31, 2018 is primarily attributable to (i) an increase in lab expenses in the amount of $734 thousand, representing an increase of 223%, as a result of an increase in new therapeutic development in the U.S. and (ii) an increase of $525 thousand, representing an increase of 164%, of Salaries and related expenses, mostly attributed to the DGO6 project.

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Selling, General and Administrative Expenses

    Three Months Ended August 31,  
    2018     2017  
    (in thousands)  
Salaries and related expenses $  1,096   $  716  
Stock-based compensation   846     270  
Accounting and legal fees   615     427  
Professional fees   730     843  
Rent and related expenses   328     320  
Business development   222     286  
Expenses related to a joint venture   -     263  
Other general and administrative expenses   171     59  
Total $  4,008   $  3,184  

Selling, general and administrative expenses for the three months ended August 31, 2018 were $4,008 thousand, as compared to $3,184 thousand for the same period in 2017, representing an increase of 26%. The increase in selling, general and administrative expenses in the three months ended August 31, 2018 compared to the same period in 2017 is primarily attributable to the following: (i) an increase in salaries as result of additional managerial positions, as well as an internal transformation program implemented in MaSTherCell in the second quarter of 2017 to evolve from an organization based on projects to a matrix organization supported by transversal departments focusing on value creation; and (ii) an increase of Stock-based compensation as a result of options granted to the CEO and certain employees. As part of the internal transformation program, managers’ position has been opened and filled by new employees either from internal appointment from the laboratories’ managers’ positions or from external new employees such as SG&A departments where several new staff members have joined in order to develop and strengthen the internal structure and SG&A departments.

Financial Expenses, net

    Three Months Ended August 31,  
    2018     2017  
    (in thousands)  
Changes in fair value financial liabilities and assets measured at fair value $  681   $  (362 )
Stock-based compensation related to warrants granted to bondholder   -     (275 )
Interest expense on convertible loans and loans   127     301  
Foreign exchange loss, net   153     289  
Other expenses   109     2  
Total $  1,070   $  (45 )

Financial expenses, net for the three months ended August 31, 2018, increased by 1,115$ thousand, compared to the same period in 2017. The increase in financial expenses is mainly attributable to the change in fair value of the put options of Atvio of $681 thousand.

Tax expenses

    Three Months Ended August 31,  
    2018     2017  
    (in thousands)  
Tax expenses   2,353     421  
Total $  2,353   $  421  

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Tax expenses for the three months ended August 31, 2018 increased by $1,932 thousand, compared to the same period in 2017. The increase in tax expenses is mainly due to a decrease in deferred taxes related to carryforward losses in MaSTherCell. This followed a Belgian tax reform bill approved in December 2017, as well as increased taxable income at Masthercell.

Comparison of the Nine Months Ended August 31, 2018 to the Nine Months Ended August 31, 2017

Our financial results for the nine months ended August 31, 2018 are summarized as follows in comparison to the nine months ended August 31, 2017:

    Nine Months Ended August 31,  
    2018     2017  
    (in thousands)  
Revenues $  12,853   $  6,712  
Cost of sales   7,220     4,900  
Research and development expenses, net   3,456     1,906  
Amortization of intangible assets   1,386     1,201  
Selling, general and administrative expenses   10,675     7,887  
Share in losses of associated company   732     348  
Financial expense, net   3,164     2,534  
Other income   (3,237 )   -  
Loss before income taxes $  10,543   $  12,064  

Revenues

    Nine Months Ended August 31,  
    2018     2017  
    (in thousands)  
Services $  9,493   $  5,600  
Goods   3,360     1,112  
Total $  12,853   $  6,712  

Our revenues for the nine months ended August 31, 2018 were $12,853 thousand, as compared to $6,712 thousand for the corresponding period in 2017, representing an increase of 91%. The increase in revenues for the nine months ended August 31, 2018 compared to the corresponding period in 2017 is attributable to an increase of $2.9 million in the volume of the services provided by MaSTherCell, resulting primarily from the extension of existing customer service contracts with biotechnology clients, as well as from revenues generated from existing manufacturing agreements.

In March 2018, MaSTherCell entered into an agreement with ZELLUNA Immunotherapy to develop and manufacture TCR adoptive cell therapy platform for which MaSTherCell has recognized revenue of approximately $515 thousand during the three months ended August 31, 2018.

In April 2018, MaSTherCell entered into an agreement with a US customer to manufacture autologous TIL therapies for which MaSTherCell has recognized revenue of approximately $1.1 million during the three months ended August 31, 2018.

In addition, we acquired all the issued and outstanding share capital of Atvio, our Israel based CDMO partner since August 2016, and 94.2% of the share capital of CureCell, our Korea based CDMO partner since March 2016, which reflected an increase in our revenues for services provided of $823 thousand during the three months ended August 31, 2018.

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Expenses

Cost of Revenues

    Nine Months Ended August 31,  
    2018     2017  
    (in thousands)  
Salaries and related expenses $  3,309   $  2,050  
Stock-based compensation   28     -  
Professional fees and consulting services   98     83  
Raw materials   3,147     1,588  
Depreciation and amortization expenses, net   293     944  
Other expenses   345     235  
  $  7,220     4,900  

Cost of revenues for the nine months ended August 31, 2018 were $7,220 thousand, as compared to $4,900 thousand, during the same period in 2017, representing an increase of 47%. The increase for the nine months ended August 31, 2018 as compared to the corresponding period in 2017 is primarily attributed to the following: (i) an increase in salaries and related expenses primarily attributable to an increase in personnel of MaSTherCell’s production, quality control and quality assurance departments in order to respond to the acquisitions of new projects and services agreement and salaries and related expenses of $740 thousand related to Atvio and CureCell; and (ii) an increase of $1,559 in raw materials due to an increase in the volume of the services provided by MaSTherCell, as well as from revenues generated from existing manufacturing agreements.

Research and Development Expenses

    Nine Months Ended August 31,  
    2018     2017  
    (in thousands)  
Salaries and related expenses $  1,497   $  872  
Stock-based compensation   446     564  
Professional fees and consulting services   273     103  
Lab expenses   1,373     881  
Depreciation expenses, net   136     -  
Other research and development expenses   256     109  
Less – grant   (525 )   (623 )
Total $  3,456   $  1,906  

Research and development expenses for the nine months ended August 31, 2018 were $3,456 thousand, as compared to $1,906 thousand for the same period in 2017, representing an increase of 81%. The increase in lab expenses in the nine months ended August 31, 2018 is primarily attributable to an increase in new therapeutic development in the U.S. and an increase in salaries and related expenses of approximately $625, mostly attributed to the DGO6 project.

Selling, General and Administrative Expenses

    Nine Months Ended August 31,  
    2018     2017  
    (in thousands)  
Salaries and related expenses $  2,999   $  1,774  
Stock-based compensation   2,333     902  
Accounting and legal fees   1,540     1,281  
Professional fees   1,704     1,568  
Rent and related expenses   905     624  
Business development   887     546  
Expenses related to a joint venture   -     865  
Other general and administrative expenses   307     327  
Total $  10,675   $  7,887  

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Selling, general and administrative expenses for the nine months ended August 31, 2018 were $10,675 thousand, as compared to $7,887 thousand for the same period in 2017, representing an increase of 35.3% . The increase in selling, general and administrative expenses in the nine-month period in 2018 compared to the same period in 2017 is primarily attributable to the following: (i) an increase of $1,225 thousand in salaries and related expenses primarily attributable to an increase in salaries as result of additional managerial positions as well as an internal transformation program implemented in MaSTherCell in the second quarter of 2017 to evolve from an organization based on projects to a matrix organization supported by transversal departments focusing on value creation; (ii) an increase of $1,431 thousand in non-cash stock-based compensation mainly resulting from grants of options to consultants and key personnel during the nine months of 2018; and (iii) a general increase in our expenses related to Atvio and CureCell.

Financial Expenses, net

    Nine Months Ended August 31,  
    2018     2017  
    (in thousands)  
Changes in fair value financial liabilities and assets measured at fair value $ 48   $  (297 )
Stock-based compensation related to warrants granted to bondholder and shares and units granted to creditor   -     1,349  
Interest expense on convertible loans and loans   2,934     987  
Foreign exchange loss, net   55     483  
Other expenses   127     12  
Total $  3,164   $  2,534  

Financial expenses, net for the nine months ended August 31, 2018, increased by 24.8%, or $630 thousand, compared to the same period in 2017. The decrease in financial expenses is mainly attributable to the following: (i) an increase of $345 thousand in the fair value of the put option of Atvio; (ii) an increase in interest expenses on convertible loans due to recognition of the unrecognized discount related to a beneficial conversion feature as additional interest expenses upon conversion of convertible loans; (iii) a decrease of $1,349 thousand due to stock-based compensation related to warrants granted to bondholder and shares and units granted to creditor.

Tax Expenses

    Nine Months Ended August 31,  
    2018     2017  
    (in thousands)  
Tax expenses   1,680     493  
Total $  1,680   $  493  

Tax expenses for the nine months ended August 31, 2018, increased by $1,187 thousand, compared to the same period in 2017. The increase in tax expenses is mainly due to a decrease in deferred taxes related to carryforward losses in MaSTherCell. This followed a Belgian tax reform bill approved in December 2017, as well as increased taxable income at Masthercell.

39


Working Capital

    August 31,     November 30,  
    2018     2017  
    (in thousands)  
Current assets $  24,654   $  7,295  
Current liabilities   14,953     16,914  
Working capital (deficiency) $  9,701   $  (9,619 )

Current assets increased by $17,359 thousand, which was primarily attributable to the following: (i) an increase in cash and cash equivalents due to proceeds from private placements of debt and equity securities, initial cash payment of $10.3 million from GPP-II to our subsidiary, Masthercell Global and an increase of $303 thousand due to the acquisition of CureCell and Atvio; (ii) an increase in inventory and accounts receivable due to the acquisition of CureCell and higher sales of MaSTherCell.

Current liabilities decreased by $1,961 thousand, which was primarily attributable to (i) a decrease of $2.4 million in current maturities of convertible loans due to the conversion of the outstanding amounts on these loans into units of shares of common stock and warrants in the nine months ended in August 31, 2018; (ii) an increase in deferred revenues of $1.3 million due to the increases sales of MaSTherCell; (iii) a decrease of $1,576 thousand in accounts payable and accrued expenses and other payables mainly as a result of new payment schedule processes and payment of debts to service providers during the nine months ended August 31, 2018.

Liquidity and Capital Resources

    Nine Months Ended August 31,  
    2018     2017  
    (in thousands)  
Net loss $  (12,223 ) $  (12,557 )
             
Net cash used in operating activities   (12,473 )   (3,436 )
Net cash used in investing activities   (4,219 )   (1,443 )
Net cash provided by financing activities   30,511     4,350  
Increase (decrease) in cash and cash equivalents $  13,819   $  (529 )

Since inception, we have funded our operations primarily through private placements and debt instruments and through revenues generated from the activities of MaSTherCell, our Belgian Subsidiary. As of August 31, 2018, we had positive working capital of $9.7 million, including cash and cash equivalents and restricted cash of $17.1 million.

Net cash used in operating activities was approximately $12.5 million for the nine months ended August 31, 2018, as compared with net cash used in operating activities of approximately $3.4 million for the same period in 2017. We expanded our pre-clinical studies in the U.S., Israel, Belgium and South Korea. The increase reflects management’s focus on moving our trans-differentiation technology with first indication in Type 1 Diabetes to the next stage towards clinical trials. We also expanded our global activity of the CDMO business with Masthercell Global, while maintaining the same level of cash used in operating activities as a result of the increased revenues at our subsidiaries MaSTherCell, CureCell and Atvio, thereby increasing gross profit and generating cash to pay our ongoing operating expenses. Additionally, we improved payment terms to our service providers.

Net cash used in investing activities for the nine months ended August 31, 2018 was approximately $4.2 million, as compared with approximately $1.4 million for the same period in 2017. Net cash used in investing activities was primarily for additions to fixed assets at our subsidiaries, MaSTherCell and CureCell.

40


During the nine months ended August 31, 2018, our financing activities consisted of (i) proceeds from private placements of our equity securities and exercise of equity-linked instruments in the net amount of approximately $16.5 million through the issuance of 1,766,369 restricted shares of common stock and additional 1,638,292 three-year warrants exercisable at a per share exercise price of $6.24 and (ii) proceeds of $720 thousand from the issuance of convertible loans from July 2016 to January 2018. Through August 31, 2018, these convertible loans were converted into units of the Company's securities, consisting of 116,296 shares of common stock and warrants to purchase 116,296 shares of common stock at a per share exercise price of $6.24.

Liquidity and Capital Resources Outlook

We believe that our business plan will provide sufficient liquidity to fund our operating needs for the next 12 months. However, there are factors that can impact our ability continue to fund our operating needs, including:

our ability to expand sales volume, which is highly dependent on implementing our growth strategy in Masthercell Global;

restrictions on our ability to continue receiving government funding for our CT business;
additional CDMO expansion into other regions that we may decide to undertake; and

the need for us to continue to invest in operating activities to remain competitive or acquire other businesses and technologies and to complement our products, expand the breadth of our business, enhance our technical capabilities or otherwise offer growth opportunities.

If we cannot effectively manage these factors, we may need to raise additional capital before such date to fund our operating needs.

From December 1, 2017 to the date of this report on Form 10-Q, we raised an aggregate of $20 million in private placements of our equity and equity-linked securities and convertible loans.

For the nine months ended August 31, 2018, we had been funding operations primarily from the proceeds from private placements of our convertible debt and equity securities and from revenues generated by MaSTherCell. From December 2017 through August 2018, we received, through MaSTherCell, proceeds of approximately $11.5 million in revenues and accounts receivable from customers and $16.5 million from the private placement to accredited investors of our equity and equity-linked securities and convertible loans.

The equity investment in November 2017 by SFPI in MaSTherCell of €5 million (approximately $5.9 million), which includes the conversion of €1 million in an outstanding loan by SFPI to MaSTherCell, will cover costs associated with an expansion of MaSTherCell’s manufacturing and production capabilities.

We believe that the investment consummated in June 2018 by an affiliate of Great Point in our newly formed subsidiary, Masthercell Global, which included an initial gross payment amount of $11.8 million and, subject to meeting certain specified financial targets and other conditions over the course of 2018 and 2019, an additional $13.2 million, should cover the costs associated with the current business plan of Masthercell Global

From September 1 through October 15, 2018, we raised $3.4 million from the institutional investor with whom we entered into definitive agreements in January 2017 for the private placement of units of our securities for aggregate subscription proceeds to us of $16 million payable through August 2018.

Off-Balance Sheet Arrangements

The Company has no off-balance sheet arrangements that have or are reasonably likely to have a current or future effect on the Company’s financial condition, changes in financial condition, revenues or expenses, results of operations, liquidity, capital expenditures or capital resources that is material to stockholders.

ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

Not applicable.

41


ITEM 4. CONTROLS AND PROCEDURES

Evaluation of Disclosure Controls and Procedures

As of August 31, 2018, we conducted an evaluation under the supervision and with the participation of our management, including our Chief Executive Officer and Chief Financial Officer, regarding the effectiveness of the design and operation of our disclosure controls and procedures as defined in Rule 13a-15(e) and 15d-15(e) of the Securities Exchange Act of 1934 (the "Exchange Act"). The term "disclosure controls and procedures" means controls and other procedures of a company that are designed to ensure that information required to be disclosed by the company in reports that it files or submits under the Exchange Act is recorded, processed, summarized and reported within the requisite time periods and that such disclosure controls and procedures were effective to ensure that information required to be disclosed by the company in the reports that it files or submits under the Exchange Act is accumulated and communicated to its management, including its principal executive and principal accounting officers, or persons performing similar functions, as appropriate to allow timely decisions regarding required disclosure. Based on the evaluation of our disclosure controls and procedures as of August 31, 2018, our principal executive officer and principal financial officer concluded that, as of such date, our disclosure controls and procedures were not effective at reasonable assurance level due to a material weakness in internal control over financial reporting, as further described below.

Management recognizes that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving their objectives and management necessarily applies its judgment in evaluating the cost-benefit relationship of possible controls and procedures. As disclosed in Item 9A of our Annual Report on Form 10-K for the year ended November 30, 2017, our management concluded that our internal control over financial reporting was not effective at November 30, 2017. A material weakness is a deficiency, or a combination of deficiencies, in internal control over financial reporting, such that there is a reasonable possibility that a material misstatement of the company’s annual or interim financial statements will not be prevented or detected on a timely basis. The limitation of our internal control over financial reporting was due to the applied risk-based approach which is indicative of many small companies with limited number of staff in corporate functions implying:

(i)

Improved but insufficient segregation of duties with control objectives; and

(ii)

Insufficient controls over period end financial disclosure and reporting processes.

Our management believes the weaknesses identified above have not had any material effect on our financial results.

We are committed to maintaining a strong internal control environment and believe that our remediation efforts specified in Item 9A of our Annual Report on Form 10-K for the year ended November 30, 2017 represent significant improvements in our control environment. We expect that our remediation efforts will continue through the end of 2018 and into 2019, although the material weakness will not be considered remediated until the applicable internal controls operate for a sufficient period, and management has concluded, through testing, that these controls are operating effectively.

From the beginning of the third quarter of 2018, management introduced internal control and review procedures including the hiring of a Sarbanes and Oxley (SOX) expert in order to remediate the material weaknesses in internal controls referred to above.

Changes in Internal Control Over Financial Reporting

We regularly review our system of internal control over financial reporting and make changes to our processes and systems to improve controls and increase efficiency, while ensuring that we maintain an effective internal control environment. Changes may include such activities as implementing new, more efficient systems, consolidating activities, and migrating processes.

42


Except for the material weakness and associated remediation plan, during the quarter ended August 31, 2018, there were no changes in our internal control over financial reporting that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

PART II – OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS

We know of no material pending legal proceedings to which the Company or its subsidiaries are a party or of which any of its properties, or the properties of its subsidiaries, are the subject. In addition, we do not know of any such proceedings contemplated by any governmental authorities.

We know of no material proceedings in which any of the Company’s directors, officers or affiliates, or any registered or beneficial stockholder is a party adverse to the Company or its Subsidiaries or has a material interest adverse to the Company or its subsidiaries.

ITEM 1A. RISK FACTORS

An investment in the Company’s common stock involves a number of very significant risks. You should carefully consider the risk factors included in the “Risk Factors” section of the Annual Report on Form 10-K for the year ended November 30, 2017, as filed with the Securities & Exchange Commission on February 28, 2018, in addition to other information contained in those reports and in this quarterly report in evaluating the Company and its business before purchasing shares of our common stock. The Company’s business, operating results and financial condition could be adversely affected due to any of those risks.

In addition, since the filing of our Annual Report on Form 10-K for the year ended November 30, 2017, we have identified the following additional risk actors:

Our subsidiary, Masthercell Global, may not receive the future payments pursuant to the Stock Purchase Agreement with GPP-II.

The purchase price for the Masthercell Global Preferred Stock was up to $25 million, subject to certain adjustments, of which $11.8 million was paid in cash at closing. The Stock Purchase Agreement also requires GPP-II to make up to two additional payments to Masthercell Global if certain specified EBITDA (as defined in the Stock Purchase Agreement) and revenue targets are satisfied by Masthercell Global during each of years 2018 and 2019. For each of those fiscal years in which such specified EBITDA and revenue targets are satisfied by Masthercell Global, GPP-II will be obligated to pay an additional $6.6 million, subject to adjustment, to Masthercell Global shortly after the end of that fiscal year. To earn such contingent payment for the 2018 fiscal year, Masthercell Global must (i) during the twelve month period ending on or prior to December 31, 2018, generate Net Revenue equal to or greater than €14,100,000 and EBITDA equal to or greater than €1,800,000, and (ii) by December 31, 2018, obtain stockholder approval of the Stockholders’ Agreement Terms in accordance with law and in a manner that will ensure that GPP-II is able to exercise its rights under the Stockholders’ Agreement without any further action or approval by GPP-II, us, our stockholders, or any other person, which includes the stockholder approval sought in our proxy statement for our annual meeting of stockholders (“Proper Approval”). To earn such contingent payment for the 2019 fiscal year, Masthercell Global must (i) during the twelve-month period ending on or prior to December 31, 2019, generate Net Revenue equal to or greater than €19,100,000 and EBITDA equal to or greater than €3,900,000, and (ii) by December 31, 2019, obtain Proper Approval, if not already obtained. Accordingly, if our stockholders do not approve the Stockholders’ Agreement Terms and do not meet the applicable Net Revenue and EBITDA targets, Masthercell Global will not be eligible to receive the future payments. In addition, in such event, GPP-II will obtain the right to put to us (or, at our discretion, to Masthercell Global if Masthercell Global shall then have the funds available to consummate the transaction) its shares in Masthercell Global.

GPP-II may force the sale of Masthercell Global which may result in GPP-II receiving a greater value than the Company and its shareholders.

43


At any time following the earlier to occur of (i) after June 28, 2020 or (ii) Masthercell Global’s failure to generate positive EBITDA for any twelve (12) month period as determined on a quarterly basis prior to June 28, 2020 or its failure to generate at least $1,000,000 of EBITDA during any such twelve (12) month period after June 28, 2020 (collectively, a “Material Underperformance Event”), GPP-II has the right, in its sole discretion, to approve and force the sale of Masthercell Global. While we have the right of first refusal with respect to acquiring Masthercell Global in the entirety, if GPP-II elects to exercise such a right, if we are not in the position to do so, GPP-II may cause the sale of Masthercell Global to any third party on terms GPP-II approves on an arm’s length basis and subject to the receipt of a fairness opinion. If this occurs, we are contractually obligated to approve such a sale and execute any documents as required by GPP-II. We must also share in any costs and expenses relating to such a sale on a pro rata basis. Based on this, there may be a situation where GPP-II approves a sale that is more valuable or beneficial to GPP-II than to our Company and our shareholders, and we will not be able to prevent such a transaction. A sale of Masthercell Global could have impacts to the CDMO activities of Orgenesis as conducted through Masthercell Global and to Orgenesis’ overall value as a whole.

GPP-II may, under certain circumstances, assume control of the Board of Directors of our subsidiary, Masthercell Global, which would result in our inability to control and direct the activities of such subsidiary.

Currently, the Board of Directors of Masthercell Global is comprised of seven (7) directors, four (4) of whom are appointed by us (one of whom must be an industry expert (the “Industry Expert Director”)) and three (3) of whom are appointed by GPP-II. In the event the Industry Expert Director is removed or replaced without the prior written approval of GPP-II, or a Material Underperformance Event has occurred after June 28, 2020, GPP-II has the right to increase the size of the Board of Directors of Masthercell Global and appoint additional directors to fill such vacancies so that GPP-II appointments represent a majority of the directors. If this were to occur, GPP-II would control the Board of Directors of Masthercell Global and will be entitled to direct its activities and approve any transactions of Masthercell Global, even if such transactions provide greater value to GPP-II than they do to Orgenesis and its stockholders. This lack of control could diminish the value of Masthercell Global as it relates to Orgenesis’ overall activity and significantly impact CDMO activities of Orgenesis as conducted through Masthercell Global.

GPP-II has the right to buy our shares in Masthercell Global upon the occurrence of certain events resulting in Orgenesis not holding any shares in Masthercell Global.

GPP-II has the right to purchase all of the shares of stock we hold in Masthercell Global if any of the following occurs: (i) there is an Activist Shareholder (as defined in the Stockholders’ Agreement) of the Company; (ii) the Chief Executive Officer and/or Chairman of the Board of Directors of Orgenesis is replaced prior to June 28, 2023; (iii) there is a Change of Control (as defined in the Stockholders’ Agreement) of Orgenesis; or (iv) the Industry Expert Director is removed or replaced without the prior written consent of GPP-II. If any of these events occur, GPP-II, upon notice to Orgenesis, can force Orgenesis to sell all of the securities it holds in Masthercell Global to GPP-II based upon a valuation of Masthercell Global to be determined by one of the top ten (10) independent third-party accounting firms in the United States with experience in performing valuations as selected by GPP-II. This right of GPP-II expires if GPP-II fails to exercise this right within three (3) years from the first occurrence of any of the events listed above. In the event GPP-II does exercise its right following the occurrence of any such event, Orgenesis shall cease to be a stockholder of Masthercell Global and will no longer derive any benefits from this subsidiary or its activities. This would also affect the CDMO activities being conducted by Orgenesis through Masthercell Global.

GPP-II has the right to effectuate a spin-off of our subsidiary, Masthercell Global

In addition to the other rights GPP-II has obtained under the Stockholders’ Agreement, GPP-II also has the right to effectuate a spin-off of Masthercell Global upon the earlier to occur of: (i) any of the four events listed in the section above or (ii) ninety (90) days after GPP-II provides Orgenesis of its intent to exercise this right provided that such notice cannot be delivered by GPP-II before June 28, 2020. Such a spin-off would be based on a valuation of Masthercell Global as determined in accordance with the terms of the Stockholders’ Agreement. If such a spin-off was to occur, Masthercell Global would no longer be a subsidiary of Orgenesis and Orgenesis would not receive the benefits or value of such a subsidiary. This would also affect the CDMO activities being conducted by Orgenesis through Masthercell Global.

44


If GPP-II opts to exchange its Masthercell Global Preferred Stock for shares of our common stock, we could potentially issue a substantial number of shares of our common stock to GPP-II, which may result in significant dilution to our existing stockholders.

The Stockholders’ Agreement provides that GPP-II is entitled, at any time, to convert its share capital in Masthercell Global for our common stock (such exchange option being the “Stock Exchange Option”). Under the Stock Exchange Option, GPP-II is entitled to exchange the Masthercell Global Preferred Stock for our common stock based on an exchange price (as defined in the Stockholders’ Agreement) that is not currently known. If GPP-II opts to exchange its Masthercell Global Preferred Stock for shares of our common stock, we could potentially issue a substantial number of shares of our common stock to GPP-II. The common stock issuable to GPP-II upon exchange of the Masthercell Global Preferred Stock for our common stock could have a depressive effect on the market price of our common stock by increasing the number of shares of common stock outstanding. Such downward pressure could encourage short sales by certain investors, which could place further downward pressure on the price of the common stock. Accordingly, the number of shares of outstanding common stock may increase significantly and the ownership interests and proportionate voting power of the existing stockholders may be significantly diluted.

ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

The following paragraph sets forth certain information with respect to all securities sold by us during the three months ended August 31, 2018 without registration under the Securities Act:

During the three months ended August 31, 2018, we entered into definitive agreements with accredited and other qualified investors relating to a private placement of 862,263 units. Each unit is comprised of (i) one share of the Company’s common stock and (ii) three-year warrant to purchase up to an additional one share of the Company’s Common Stock at a per share exercise price of $6.24, for aggregate proceeds to the Company of approximately $5.6 million.

These securities were not registered under the Securities Act of 1933, as amended (the "Securities Act"), but qualified for exemption under Section 4(a)(2) of the Securities Act and Regulation S promulgated thereunder. The securities were exempt from registration under Section 4(a)(2) of the Securities Act and Regulation S because the issuance of such securities by the Company did not involve a "public offering," as defined in Section 4(a)(2) of the Securities Act, the Investor’s representations that it is not a U.S. Person as that term is defined in Rule 902(k) of Regulation S, and that it is acquiring the securities for its own account for investment purposes and not as nominee or agent, and not with a view to the resale or distribution thereof, and that the investor understands that the securities may not be sold or otherwise disposed of without registration under the Securities Act and any applicable state securities laws, or an applicable exemption therefrom.

ITEM 3. DEFAULTS UPON SENIOR SECURITIES

None.

ITEM 4. MINE SAFETY DISCLOSURES

Not Applicable.

ITEM 5. OTHER INFORMATION

In October 2018, the Company raised $3.4 million from the institutional investor referred to in Note 7 entitling such investor to 550,481 shares of Common Stock and three-year warrants for an additional 550,481 shares. Following this remittance and those referred to in Note 7, the Company has received, as of October 12, 2018, a total of $16 million out of the committed $16 million subscription proceeds under such agreement.

45


The issuance of shares of Orgenesis common stock to these investors will be made in reliance on one or more exemptions or exclusions from the registration requirements of the Securities Act of 1933, as amended (the "Securities Act"), including Section 4(a)(2) of the Securities Act, Regulation D promulgated under the Securities Act, and Regulation S promulgated under the Securities Act, and the exemption from qualification under applicable state securities laws.

46


ITEM 6. EXHIBITS

No. Description
(10) Material Agreements
10.1* Collaboration and License Agreement, dated as of June 18, 2018, between Orgenesis Inc. and Mircod Limited
(31) Rule 13a-14(a)/15d-14(a) Certification
31.1* Certification Statement of the Chief Executive Officer pursuant to Section 302 of the Sarbanes Oxley Act of 2002
31.2* Certification Statement of the Chief Financial Officer pursuant to Section 302 of the Sarbanes Oxley Act of 2002
(32) Section 1350 Certification
32.1* Certification Statement of the Chief Executive Officer pursuant to Section 906 of the Sarbanes Oxley Act of 2002
32.2* Certification Statement of the Chief Financial Officer pursuant to Section 906 of the Sarbanes Oxley Act of 2002
(101)* Interactive Data Files
101.INS XBRL Instance Document
101.SCH XBRL Taxonomy Extension Schema Document
101.CAL XBRL Taxonomy Extension Calculation Linkbase Document
101.DEF XBRL Taxonomy Extension Definition Linkbase Document
101.LAB XBRL Taxonomy Extension Label Linkbase Document
101.PRE XBRL Taxonomy Extension Presentation Linkbase Document

* Filed herewith.

47


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

ORGENESIS INC.
 
By:
 
/s/ Vered Caplan
Vered Caplan
President & Chief Executive Officer
(Principal Executive Officer)
Date: October 12, 2018
 
 
/s/ Neil Reithinger
Neil Reithinger
Chief Financial Officer, Treasurer and Secretary
(Principal Financial Officer and Principal Accounting
Officer)
Date: October 12, 2018

48


EX-10.1 2 exhibit10-1.htm EXHIBIT 10.1 Orgenisis, Inc. - Exhibit 10.1 - Filed by newsfilecorp.com

COLLABORATION AND LICENSE AGREEMENT

This Collaboration and License Agreement (this “Agreement”) is entered into as of 8th of June, 2018 (“Effective Date”), by and between Mircod Limited., a company duly registered under the laws of Cyprus having an address at Nikodimou Milona 28, Limassol 3095 (“Mircod”) and Orgenesis, Inc, having an address at 20271 Goldenrod Lane, Germantown, Md, 20876, USA (“ORGS”).

(Mircod and ORGS may be individually referred to as a “Party” and collectively as the “Parties”)

WHEREAS, Mircod is engaged in development of Hardware and Software IoT related solutions; and

WHEREAS, ORGS is a company engaged in the development of innovative therapeutic products; and

WHEREAS, the Parties wish to collaborate in the adaptation of the Mircod Background Technology (as defined below) for use for biological related development and manufacturing purposes and to meet the specifications set forth in Exhibit A attached hereto, all in accordance with the development plan to be agreed upon in writing by the Parties within forty five (45) days following the Effective Date and once so agreed, to be attached as Exhibit B hereto as (the “Development Plan” and the “Project”, respectively); and

WHEREAS, following the completion of the Project, ORGS will be granted an exclusive, worldwide sublicensable license to use and commercialize the Project Results and the Products (as defined below) all subject to and in accordance with the terms and conditions of this Agreement.

NOW THEREFORE IT IS AGREED BETWEEN THE PARTIES AS FOLLOWS:

 
1.
Definitions
 
Terms defined in this Section 1 and elsewhere, parenthetically, in this Agreement, shall have the same meaning throughout this Agreement. Defined terms may be used in the singular or in the plural.
  
1.1
Affiliate” shall mean, as to either Party, any corporation which controls, is controlled by, or is under common control with, such Party; A corporation shall be deemed to control another corporation if it owns, directly or indirectly, more than 50% (fifty percent) of the voting shares, or has the power to elect more than half of the directors, of such other corporation;
 
1.2

Mircod Background Patents” shall mean all patent applications or applications for certificates of inventions owned or controlled by Mircod, covering Mircod Background Technology and all patents or certificates of invention which may be granted thereon; as well as all continuations, continuations-in-part, patents of addition, divisions, renewals, reissues and extensions (including any patent term extension) of any of the foregoing patents. The existing patent application(s) that form part of the Mircod Background Patents are listed in Exhibit C, attached hereto as related to the project ;


  -1-  


DocuSign Envelope ID: 3B4C4D47-E591-43A3-85AB-C2386A451338

  1.3.

Mircod Background Technology” any and all existing inventions, patent applications, patents, know-how and other intellectual property rights owned or licensed by Mircod relating to Hardware and Software IoT technologies as related to the project.

     
  1.4.

Net Sales” shall mean the total amount actually received by ORGS and/or its Affiliates in connection with the sale, of a Product after deduction of: (i) sales taxes to the extent applicable to such sale and included in the invoice in respect of such sale; (ii) credits or allowances, if any, actually granted on account of price adjustments, recalls, rejections or returns of a Product previously sold; (iii) freight and insurance charges to the extent such items are applicable to such sale and are separately itemized on invoices; and (iv) bad debts (as determined in accordance with relevant GAAP rules) deriving from Net Sales in respect of which payments were made by ORGS to Mircod pursuant to Section 4.3 hereunder.

     
  1.5.

Products” means any biological system or device incorporating Project Results.

     
  1.6.

Project Budget” shall mean the budget for the Project to be paid by ORGS to Mircod, in the amounts as set forth in the Development Plan;

     
  1.7.

Project Results” shall mean any and all inventions, patents or patent application, products, materials, compounds, formulas, substances, methods, processes, techniques, know-how, data, information and/or other results, including, any improvements on and/or modifications to the Mircod Background Technology, developed, by Mircod, and/or anyone on its behalf and/or ORGS its Affiliates and/or anyone on their behalf , alone or together with others, in the course of and arising from the performance of the Project, including any regulatory filing filed, or approval obtained, as well as any information, material, results, devices and know-how arising therefrom.

     
  1.8.

“ORGS Background Technologyany and all existing inventions, patent applications, patents, know-how and other intellectual property rights owned or licensed by ORGS and/or any of its Affiliates.

     
  1.9.

“ORGS Background Patentsall patent applications or applications for certificates of inventions owned or controlled by ORGS and/or any of its Affiliates, covering ORGS Background Technology and all patents or certificates of invention which may be granted thereon; as well as all continuations, continuations-in-part, patents of addition, divisions, renewals, reissues and extensions (including any patent term extension) of any of the foregoing patents.

     
  1.10.

“Resulting Patents” shall mean all patent applications or applications for certificates of invention describing or covering any Project Results and all patents or certificates of invention which may be granted thereon; as well as all improvements, continuations, continuations-in-part, patents of addition, divisions, renewals, reissues and extensions (including any patent term extension) of any of the foregoing patents, but excluding: (a) patents that have been invalidated or cancelled pursuant to the final (i.e., unappealed or unappealable) judgment of a competent court; and (b) patent applications that have been withdrawn or have expired, in each case such exclusion to be effective only from the date of such invalidation, cancellation, withdrawal or expiry, as the case may be.


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2.

The Project and the Project Results


  2.1.

Each Party agrees to use commercially reasonable efforts to perform its respective responsibilities and to allocate sufficient resources to complete the relevant Project obligations in accordance with the Development Plan to be approved and signed by both Parties within forty five (45) days following the Effective Date. Each of the Parties shall perform its respective obligations under this Agreement and/or the Development Plan in accordance with all applicable laws, regulations and standards.

     
  2.2.

Either Party may subcontract any portion of the obligations under this Agreement and/or a Development Planto an Affiliate thereof, provided that such Party shall remain responsible for the performance or non-performance of its obligations under this Agreement and/or the Development Plan and shall keep each the other informed with respect to any subcontractors engaged hereby in the implementation of the Development Plan.

     
  2.3.

The Parties shall establish a Joint Project Team ("JPT") promptly after the Effective Date. The JPT shall coordinate all applicable activities relating to the Project. Each Party shall appoint representatives who are employees of such Party to the JPT and the JPT shall consist of an equal number of representatives of each Party as are reasonably necessary to accomplish the goals of the JPT hereunder. The number of representatives may change from time to time. One such representative from each Party shall be designated as that Party's "Project Team Leader" to act as the primary JPT point of contact (POC) for that Party. Each Party may replace any or all of its representatives with other employees of such Party at any time. Any member of the JPT may designate a substitute employee of such Party to attend and perform the functions of that member at any meeting of the JPT. The JPT will meet in person or by conference call on a regular basis, not less than one (1) time per month and/or upon the written request of either Party.

     
  2.4.

Any changes to the Development Plan shall be subject to the written consent of both Parties.

     
  2.5.

Subject to and in consideration for performing its obligations with respect to the Project, ORGS undertakes to pay Mircod the amounts set forth in the Project Budget in US Dollars in separate payments per stage of the Project as set forth in the Development Plan and the Project Budget. All payment shall be made against invoices to be issued by Mircod in accordance to the payment schedule set forth in the Project Budget. All undisputed invoices shall be paid within thirty (30) days of receipt by ORGS of the applicable invoice.



  -3-  


  2.6.

Mircod hereby grants ORGS and its Affiliates a royalty free non-exclusive license under the MIRCOD Background Technology and any Mircod Background Patents to the extent required to carry out ORGS’ respective tasks under the Project.

   

 

  2.7.

ORGS hereby grants Mircod and its Affiliates a royalty free non-exclusive license under the ORGS Background Technology and any ORGS Background Patents to the extent required to carry out Mircod’s respective tasks under the Project.

   

 

  2.8.

The estimated Budget for the Project is __________US Dollars ($___________) per month for a period of ________________months. The final Budget shall be finalized and shall be agreed upon by the parties as part of the Development Plan.

   

 

 

Subject to Mircod carrying out is tasks under the Development Plan, ORGS shall pay Mircod such amounts to be set forth in the Budget in accordance with the payment terms set forth therein.

   

 

  2.9.

Within seven (7) days following the signing of this Agreement, ORGS will pay Mircod an advance payment in the amount of Fifty Thousand US Dollars (US$50,000) on account of amounts payable to Mircod in accordance with the Budget.

   

 

  2.10.

Any payment due to Mircod hereunder shall be inclusive of any and all taxes other tan VAT to the extent apllcable. ORGS may deduct withholding tax (if any) as prescribed by applicable law from any payments due to Mircod hereunder unless Mircod provides ORGS with evidence of any exemption from the payment of such withholding tax.


3.

Intellectual Property

     
3.1.

Subject to the licenses to be granted to ORGS under Sections 2.6 above and 0 below, all rights and interests in and to the Mircod Background Technology and Mircod Background Patents shall remain the exclusive property of Mircod.


  3.2.

, All rights and interests in and to the ORGS Background Technology and ORGS Background Patents shall remain the sole property of ORGS.

     
 

All rights and interests in and to the Project Results and Resulting Patnets shall be jointly owend by the Parties in eqal shares


4.

Grant of License; Royalties

     
4.1.

Mircod hereby grants to ORGS and/or its Affiliates: (i) an exclusive (including with respect to MIRCOD), worldwide sublicensable license to use and commercialize Mircos’d rights in the Project Results and any Resulting Patents to sell, have sold, use, have used and otherwise commercialize the Products; and (ii) a nonexclusive worldwide sublicensable license under the Mircod Background Technology and/or Mircod Background Patents to the extent required, to use [and commercialize] the Project Results and/or any Resulting Patents to develop, have developed, make, have made, sell, have sold, use, have used, import, have imported, and otherwise commercialize the Products (collectively the “License”).



  -4-  


4.2.

With Mircod’s reasonable consent, ORGS may grant sublicenses under the License, throughis made by written agreement, the provisions of which are consistent with the terms of this Agreement. including the payment of Royalties on the sublicensee’s Net Sales.

   

 

4.3.

In consideration for the grant of the License, ORGS shall pay Mircod, royalties of 5 % (five percent) on Net Sales arising from the sale of Products (“Royalties”).

   

 

  4.4.

ORGS shall submit to Mircod, no later than 30 (thirty) days after the end of each calendar quarter, commencing with the first calendar quarter in which any Net Sales are generated, a detailed report, setting out all amounts owing to Mircod in respect of such previous calendar quarter to which the report refers, and with full details of: (i) the sales made by the ORGS, including a breakdown of Net Sales according to currency of sales, dates of invoices, number and type of Product sold; and (ii) deductions applicable, as provided in the definition of “Net Sales. The foregoing reports submitted by ORGS shall be deemed Confidential Information (as defined below) of ORGS and shall be subject to the provisions of Section 8 below.

     
  4.5.

ORGS shall keep complete, accurate and correct books of account and records consistent with sound business and accounting principles and practices and in such form and in such details as to enable the determination of the amounts due to Mircod in accordance with the terms hereof. ORGS shall retain the foregoing books of account for 3 (three) years after the end of each calendar year during the period of this Agreement, and, if this Agreement is terminated for any reason whatsoever, for 3 (three) years after the end of the calendar year in which such termination becomes effective.

     
  4.6.

Mircod, at its own expense, shall be entitled, no more than once during any calendar year, to appoint representatives to inspect during normal business hours and to make copies of ORGS’s books of account, records and other documentation (including technical data and lab books) to the extent relevant or necessary for the ascertainment or verification of the amounts due to it under this Section 0, provided however that Mircod shall coordinate such inspection with ORGS in advance. In the event that any inspection as aforesaid reveals any underpayment by ORGS to Mircod in respect of any year of the Agreement in an amount exceeding 5% (five percent) of the amount paid by ORGS to Mircod in respect of such year then ORGS shall (in addition to paying Mircod the shortfall), bear the costs of such inspection. The foregoing books of account, records and other documentation (including technical data and lab books) of ORGS shall be deemed Confidential Information of ORGS and shall be subject to the provisions of Section 8 below.


5.

Manufacturing and Supply Agreement; JV


  5.1.

Upon and subject to successful completion of the Project, the Parties shall negotiate in good faith and agree on the terms of a manufacturing and supply agreement between Mircod and ORGS and/or its Affiliates (“Manufacturing and Supply Agreement”), under which Mircod shall manufacture and supply the Products to ORGS and/or its Affiliates and, at ORGS’ and/or its Affiliates’ request, to provide support and maintenance services for the Products, including for purposes of ORGS and/or its Affiliates providing Contract Development and Manufacturing services. The Manufacturing and Supply Agreement shall also include provisions under which, Mircod shall, at ORGS’ and/or its Affiliates’ request, provide additional services to incorporate any updates to and/or improvements on the Mircod Background Technology which



  -5-  


  5.2.

In no event shall Mircod and/or its Affiliates be entitled to develop and/or manufacture the Products and/or otherwise make use of the Project Results and/or Resulting Patents, directly or indirectly, for any purpose other than manufacturing and supplying Products to ORGS and/or its Affiliates pursuant to such Manufacturing and Supply Agreement.

     
  5.3.

In the event that the Parties fail to enter into Manufacturing and Supply Agreement, despite good faith negotiation, within ninety (90) days following completion of the Project, and/or in the event that Mircod is unable to manufacture and/or supply the Products to ORGS and/or its Affiliates and/or provide support and maintenance service for the Products, then:


  5.3.1.

ORGS and/or its Affiliates shall pay Mircod a onetime amount of Eighty Thousand US Dollars ($80,000) + VAT to the extent applicable; the scope of the License granted under Section 4.1 above shall be expanded so that ORGS and/or its Affiliates shall also have the worldwide exclusive right and sublicensable license, to develop, have developed, manufacture, have manufactured, make and/or have made, service, have serviced the Products; and

     
  5.3.2.

the Royalties to be paid to Mircod under Section 4.3 above shall increase to eight percent (8 %) on Net Sales arising from the sale of Products. In addition to any payments, if any due to Mircod under any future Support Agreement, if any).


  5.4.

At any time, during the term of this Agreement, ORGS shall have the option, at its sole discretion, to transfer and require Mircod to transfer the Project and/or the rights and licenses granted hereunder by Mircod to ORGS, to a Joint Venture company which to be established by the Parties in Canada under the name of Mircod Biotech, or any other name agreed upon in writing by the Parties (“JV Entity”), for purposes of carrying out the Project and/or commercializing the Products.

     
 

The relative shareholdings of each Party in the JV Entity will be based on the following participating interests of each Party (“Participating Interest”): ORGS - 50% and Mircod or its Affiliate - 50%.



  -6-  


6.

Patent Prosecution

     
6.1.

Mircod shall, at its own cost and expense, in consultation with ORGS, administer and control all patent activities (including the filing, recording, prosecution and/or maintenance of patent applications and patents) with respect to the Mircod Background Patents, subject to the provisions of this Section 6 below.

   

 

6.2.

Mircod shall deliver to ORGS, within a reasonable time, copies of all: (i) draft and final patent office filings and other submissions with respect to Mircod Background Patents; and (ii) correspondence between Mircod or Mircod's patent counsel and any competent authority (where such Mircod Background Patents may be filed, maintained or made) relating to the prosecution and/or maintenance of such Mircod Background Patents, and provide ORGS with a reasonable opportunity to review and discuss with Mircod prosecution strategy and to consult with Mircod on the content of patent filings with respect to such Mircod Background Patents. At least sixty (60) days prior to any date prescribed by the relevant patent office or by applicable law for the taking of action with respect to the prosecution and/or maintenance of such Mircod Background Patents, Mircod or its patent counsel shall provide written notice to ORGS of: (a) such date; (b) whether or not Mircod intends to take such action; and (c) if so, what action Mircod intends to take. Mircod hereby agrees to irrevocably instruct its patent counsel to comply with the preceding sentence. In the event Mircod declines to pursue the filing, prosecution or maintenance of any such Mircod Background Patent, Mircod shall provide reasonable prior written notice to ORGS of its intention to cease such pursuit (which notice shall, in any event, be given no later than 60 (sixty) days prior to the next deadline for any action that may be taken with respect to such Mircod Background Patent with the applicable patent office), and ORGS may, at its own expense, control and administer the filing, prosecution, or maintenance of such Mircod Background Patent.

   

 

6.3.

ORGS shall, at its own cost and expense, in consultation with Mircod, administer and control all patent activities (including the filing, recording, prosecution and/or maintenance of patent applications and patents) with respect to the Resulting Patents, subject to the provisions of this Section 6 below.

   

 

6.4.

ORGS shall deliver to Mircod, within a reasonable time, copies of all: (i) draft and final patent office filings and other submissions with respect to Resulting Patents; and (ii) correspondence between ORGS or ORGS' patent counsel and any competent authority (where such Resulting Patents may be filed, maintained or made) relating to the prosecution and/or maintenance of such Resulting Patents, and provide Mircod with a reasonable opportunity to review and discuss with ORGS prosecution strategy and to consult with ORGS on the content of patent filings with respect to such Resulting Patents. At least sixty (60) days prior to any date prescribed by the relevant patent office or by applicable law for the taking of action with respect to the prosecution and/or maintenance of such Resulting Patents, ORGS or its patent counsel shall provide written notice to Mircod of: (a) such date; (b) whether or not ORGS intends to take such action; and (c) if so, what action ORGS intends to take. ORGS hereby agrees to irrevocably instruct its patent counsel to comply with the preceding sentence. In the event ORGS declines to pursue the filing, prosecution or maintenance of any such Resulting Patent, Mircod shall provide reasonable prior written notice to Mircod of its intention to cease such pursuit (which notice shall, in any event, be given no later than 60 (sixty) days prior to the next deadline for any action that may be taken with respect to such Resulting Patent with the applicable patent office), and Mircod may, at its own expense, control and administer the filing, prosecution, or maintenance of such Resulting Patent.



  -7-  


  6.5.

Mircod warrants that to the best of its knowledge, the exploitation of the Mircod Background Technology and/or Mircod Background Patents will not infringe on and/or misappropriate the rights of any third party.


7.

Patent Enforcement

     
7.1.

ORGS shall have the first right in its own name and at its own expense to initiate any legal action and enforce the Resulting Patents against any infringement thereof. Before ORGS commences an action with respect to any infringement, ORGS shall consider the views of Mircod in making its decision whether or not to initiate any legal action. Mircod shall cooperate with ORGS and/or its representatives, in connection with the investigation, prosecution or defense of any such infringement action against a third party, at ORGS’s expense, and, if required under applicable law, Mircod shall consent to be named a party to any such action.

     
7.2.

Any proceeds received by ORGS in any litigation as referred to in Section 7.1 above, shall first be applied to cover out of pocket costs and thereafter shall be owned by ORGS.

     
7.3.

If ORGS fails to take action to defend any action as aforesaid, within 60 (sixty) days after having been duly served with such lawsuit and/or receiving notice from Mircod in respect thereof (or within a shorter period, if required to preserve the legal rights of Mircod under applicable law), then Mircod shall have the right (but not the obligation) to take such action at its expense and ORGS shall cooperate in the investigation and defense of such action, at Mircod's expense and, if required under applicable law or contract, consent to be named as a party to any such action. Mircod shall have full control of such action and shall have full authority to settle such action on such terms as Mircod shall determine. Any recovery in any such litigation shall be for the account of Mircod only.


8.

Confidentiality

     
8.1.

As used in this Agreement, "Confidential Information" means nonpublic information, data and/or materials that may be disclosed by or on behalf of one Party (the "Disclosing Party") to the other Party (the "Receiving Party") in connection with this Agreement, in whatever form, provided that such information is clearly marked as confidential. Information disclosed other than in written or other tangible form will be deemed Confidential Information only if the Disclosing Party provides the Receiving Party with a written statement within thirty (30) days of the initial disclosure that identifies which portion of such information is to be deemed Confidential Information. Notwithstanding the forgoing, the failure to mark or identify information as confidential shall not shall not prevent its being treated as Confidential Information if it is reasonably clear that such information is commercially sensitive information. The Receiving Party agrees (i) to use such Confidential Information of the Disclosing Party solely for performing its obligations and/or exercising it rights under this Agreement; and (ii) except as otherwise expressly permitted herein, to not disclose such Confidential Information of the Disclosing Party to any Third Party without prior written permission. Notwithstanding the forgoing, all information or data relating to the Project Results and/or Resulting Patents shall be considered as Confidential Information of both Parties, provided however, that Project Results and/or Resulting Patents may be used and/or disclosed by ORGS and/or its Affiliates in connection with commercialization of the Project Results and/or Products and/or otherwise in exercising the License and by Mircod – in connection with supply and/or manufacturing of the



  -8-  


 

The foregoing confidentiality obligations do not pertain to any Confidential Information that a Receiving Party establishes: (i) was known to the Receiving Party without restriction prior to receipt from the Disclosing Party; (ii) is now or becomes public knowledge, other than through acts or omissions of the Receiving Party and/or anyone on its behalf in breach of this Agreement; (iii) is disclosed at any time without restriction to the Receiving Party by a third party with a lawful right to disclose such information; (iv) was independently developed by or on behalf of the Receiving Party, outside the scope of this Agreement, without use of and/or reference to the Confidential Information of the Disclosing Party; or (v) is disclosed by the Receiving Party to comply with any applicable law, court order or governmental regulation, only to the minimum extent required to comply with such law, order, or regulation, provided that the Receiving Party shall, to the extent permissible, provide prior notice of such required to the Disclosing Party.

     
  8.2.

Without limiting the Parties' obligations, the Parties shall hold in confidence and not disclose the terms and conditions of this Agreement Notwithstanding the foregoing, a Party may disclose the existence and terms and condition of this Agreement and material developments hereunder (i) to the extent required to comply with applicable law (including but not limited to securities laws and regulations) or the listing requirements of a securities exchange, provided that such Party use reasonable efforts to seek and obtain confidential treatment as permitted under such applicable laws and listing requirements and/or (ii) to bona fide potential investors, acquirers, merger partners, collaborators or licensees, or to professional advisors (e.g. attorneys, accountants and prospective investment bankers) involved in such activities, for the limited purpose of evaluating such investment, transaction, or license and under appropriate conditions of confidentiality, only to the extent necessary and with the agreement by those permitted individuals to maintain such information in strict confidence

     
  8.3.

Each Party shall be entitled to disclose Confidential Information of the other Party to its Affiliates and to their respective officers, employees, consultants provided that they have a need to know such Confidential Information and are bound by confidentiality and non-sue obligations no less protective of the Disclosing Party`s rights as those under this Agreement.


  -9-  



  8.4.

Upon the termination of this Agreement or, if earlier, upon the written request by Disclosing Party at any time, Receiving Party shall promptly (within 14 (fourteen) days) return or destroy (at the direction of Disclosing Party) all Confidential Information to Disclosing Party and all documents or media containing any such Confidential Information, retaining only one copy for archival purposes only. Notwithstanding the foregoing, it is agreed that Receiving Party shall not be required to destroy any computer files created during automatic system back up which are subsequently stored securely by Receiving Party.

     
  8.5.

Notwithstanding the provisions of this Section 8 above, ORGS shall not be prevented from mentioning the name of Mircod, and/or any employee of Mircod or from disclosing any information if, and to the extent that, such mention or disclosure is to competent authorities for the purposes of obtaining approval or permission for the exercise of the License, or in the fulfillment of any legal duty owed to any competent authority (including a duty to make regulatory filings.


9.

Assignment

   

ORGS shall have the right assign to a third party its rights and obligations under this Agreement, subject to the delivery to Mircod, at least 3 (three) business days prior to the consummation of such assignment of: (i) from the assignee, a written undertaking, to be bound by the terms of this Agreement and to perform all obligations of ORGS hereunder; and (ii) from ORGS, a written confirmation, that ORGS is not in breach of any of its obligations under this Agreement. In the case of such an Assignment, ORGS shall remain responsible in relation to Mircod for the performance or non-performance by the third party of ORGS' obligations under this Agreement and/or the Development Plan.

   
10.

Indemnification; Limitation of Liability


  10.1.

Indemnification by ORGS. ORGS shall indemnify, defend and hold Mircod and its employees, officers, directors and agents (each a “Mircod Indemnitee”) harmless from and against any and all actions, judgments, settlements, liabilities, damages, penalties, fines, losses, costs and expenses (including reasonable attorneys’ fees and expenses) to the extent arising out of any third party claim, demand, action or other proceeding (each, a



  -10-  


Claim”) to the extent arising out of or resulting from (a) the commercialization (including testing, handling, storage, transportation, sale or use or other disposition) of the Products by or on behalf of ORGS or its Affiliates or Sublicensees (except is such activities are carried out by Mircod and/or any of its Affiliates); (b) ORGS’s, its Affiliates and/or Sublicensees’ use or practice of the Mircod Background Technology, Mircod Background Patents, Project Results, Resulting Patents; (c) breach by ORGS of any of its representations, warranties, covenants or obligations set forth in this Agreement; (d) a ORGS Indemnitee’s or any of ORGS’s Affiliates, or Sublicensees’ gross negligence, recklessness or willful misconduct; provided however, that ORGS’s obligations pursuant to this Section 10.1shall not apply to the extent such Claims arise out of or result from Mircod’s breach of this Agreement or the negligence, recklessness or willful misconduct of any Mircod Indemnitee and/or otherwise due to a cause which gives rise to indemnification by Mircod under Section 10.2 below.

     

10.2.

Indemnification by Mircod. Mircod shall indemnify, defend and hold ORGS and its Affiliates and each of their respective agents, employees, officers and directors (each a “ORGS Indemnitee”) harmless from and against any and all Claims to the extent arising out of or resulting from (a) the development or manufacture (including testing, handling, storage, transportation, use or other disposition) of any Product by or on behalf of Mircod or its Affiliates or licensees; (b) use or practice of the Mircod Background Technology, Mircod Background Patents, Project Results, Resulting Patents infringe on and/or misappropriate any third party’s intellectual property; (c) breach by Mircod of any of its representations, warranties, covenants or obligations set forth in this Agreement, or (d) a Mircod Indemnitee’s gross negligence, recklessness or willful misconduct; provided, however, that Mircod’s obligations pursuant to this Section 10.2 shall not apply to the extent such Claims arise out of or result from ORGS’s breach of this Agreement or the negligence, recklessness or willful misconduct of any ORGS Indemnitee.

     
  10.3.

Procedure.


  10.3.1.

The Party or other person intending to claim indemnification under this Section 10 (an “Indemnified Party”) shall promptly notify the other Party (the “Indemnifying Party”) of any Claim in respect of which the Indemnified Party intends to claim such indemnification (provided, that no delay or deficiency on the part of the Indemnified Party in so notifying the Indemnifying Party shall relieve the Indemnifying Party of any liability or obligation under this Agreement except to the extent the Indemnifying Party has suffered actual prejudice directly caused by the delay or other deficiency), and the Indemnifying Party shall have the right to assume full control over the defense and settlement thereof provided, however, that an Indemnified Party shall have the right to retain its own counsel and to participate in the defense thereof, with the fees and expenses to be paid by the Indemnified Party unless the Indemnifying Party does not assume the defense.

     
  10.3.2.

If the Indemnifying Party shall fail to timely assume the defense of and reasonably defend such Claim, the Indemnified Party shall have the right to retain or assume control of such defense and the Indemnifying Party shall pay (as incurred and on demand) the fees and expenses of counsel retained by the Indemnified Party.

     
  10.3.3.

The Indemnifying Party shall not be liable for the indemnification of any Claim settled (or resolved by consent to the entry of judgment) without the written consent of the Indemnifying Party. The Indemnifying Party shall obtain the prior written consent (which shall not be unreasonably withheld or delayed) of the Indemnified Party before entering into any settlement of (or resolving by consent to the entry of judgment upon) such Claim unless (i) there is no finding or admission of any violation of law or any violation of the rights of any person by an Indemnified Party, no requirement that the Indemnified Party admit negligence, fault or culpability, and no adverse effect on any other claims that may be made by or against the Indemnified Party and (ii) the sole relief provided is monetary damages that are paid in full by the Indemnifying Party and such settlement does not require the Indemnified Party to take (or refrain from taking) any action.


  -11-  



  10.3.4.

The Indemnified Party, and its employees and agents, shall cooperate fully with the Indemnifying Party and its legal representatives in the investigations of any Claim. Regardless of who controls the defense, each Party hereto shall reasonably cooperate in the defense as may be requested.


  10.4.

Limitation of Liability. In no event shall either Party or its Affiliates be liable to the other Party for any punitive, exemplary or consequential damages arising out of a breach of this Agreement, provided that, notwithstanding anything to the contrary, the foregoing shall not be construed to limit the indemnity obligations set forth in Sections 10.1 and 10.2or either Party’s liability for a breach of Section 8.

     
  10.5.

The provisions of this Section 10 shall survive the termination of this Agreement for whatsoever reason.


11.

Term and Termination

     
11.1.

The term of this Agreement shall commence when this Agreement is signed by both Parties (the “Effective Date”) and, unless terminated as provided in this Section 11, shall continue in full force and effect thereafter.

     
11.2.

Without derogating from the Parties' rights hereunder or by law to any other or additional remedy or relief, it is agreed that either Party may terminate this Agreement and the License hereunder by serving a written notice to that effect on the other upon or after:


  11.2.1.

the commitment of a material breach hereof by the other Party, which material breach cannot be cured or, if curable, which has not been cured by the Party in breach within thirty (thirty) days after receipt of a written notice from the other Party in respect of such breach, or

     
  11.2.2.

the granting of a winding-up order in respect of the other Party, or upon an order being granted against the other Party for the appointment of a receiver, or if such other Party passes a resolution for its voluntary winding-up, or if a temporary or permanent liquidator or receiver is appointed in respect of such other party, or if a temporary or permanent attachment order is granted on such other party's assets, or a substantial portion thereof, or if such other Party shall seek protection under any laws or regulations, the effect of which is to suspend or impair the rights of any or all of its creditors, or to impose a moratorium on such creditors; provided that in the case that any such order or act is initiated by any third party, the right of termination shall apply only if such order or act as aforesaid is not cancelled within 60 (sixty) days



  -12-  


  11.3.

Upon the termination of this Agreement by Mircod pursuant to Section 11.2, the License granted to ORGS under Section 4.1 shall terminate. , it being undertoof however, that Mircod shall not be entitled to make use of the Project Results and/or Resulting Patents, without prior consent of ORGS.

     
  11.4.

Neither expiration of this Agreement, nor termination of this Agreement for any reason, shall relieve the Parties of any obligation accruing prior thereto and shall be without prejudice to the rights and remedies of either Party with respect to any antecedent breach of the provisions of this Agreement.

     
  11.5.

Without limiting the generality of the foregoing, no expiration or termination of this Agreement, whether by lapse of time or otherwise, shall serve to terminate the obligations of the Parties hereto under Sections 1, 3, 8, 10, 11.3 through 11.5, 13 and 14 shall survive any such expiration or termination.


12.

Notices

   

Any notice or other communication required to be given by one Party to the other under this Agreement shall be in writing and shall be deemed to have been served: (i) if personally delivered, when actually delivered; or (ii) if sent by facsimile or electronic mail, upon transmission thereof, if during normal business hours, and if not then at the start of business on the first business day thereafter (provided that any notice terminating this Agreement which is sent by electronic mail shall be followed by a notice sent in any other manner provided herein), or (iii) 10 (ten) days after being mailed by certified or registered mail, postage prepaid (for the purposes of proving such service - it being sufficient to prove that such notice was properly addressed and posted) to the respective addresses of the Parties set out below, or to such other address or addresses as any of the Parties may from time to time in writing designate to the other Party pursuant to this Section 12:

   
 


  -13-  

With Copy to (which such copy shall not constitute notice):

  Mark Cohen, Esq.
  Pearl Cohen Zedek Latzer Baratz LLP
  1500 Broadway
  New York, NY 10036
  USA
  Email: MCohen@PearlCohen.com

13.

Governing Law and Jurisdiction

   

This Agreement shall be governed in all respects by the laws of the State of New York, USA (without application of is conflict of law provisions directing that the laws of another jurisdiction shall apply), and the Parties hereby irrevocably submit to the exclusive jurisdiction of the of federal and state courts located in New York County, New York, USA, with respect to any dispute and/or claim arising form and/or related to this Agreement.

   
14.

Miscellaneous


  14.1.

The preamble and Exhibits hereto form an integral part of this Agreement.

     
 

In this Agreement “including” or “includes” means including without limiting the generality of any description preceding such terms. The headings in this Agreement are intended solely for convenience or reference and shall be given no effect in the interpretation of this Agreement.

     
  14.2.

This Agreement constitutes the entire agreement between the Parties in respect of the subject-matter hereof, and supersedes all prior agreements or understandings between the Parties relating to the subject-matter hereof. No Party has, in entering into this Agreement, relied on any warranty, representation or undertaking, except as may be expressly set out herein.

     
  14.3.

This Agreement may be amended only by a written document signed by both Parties.

     
  14.4.

This Agreement may be executed in any number of counterparts (including counterparts transmitted by email or fax), each of which shall be deemed to be an original, but all of which taken together shall be deemed to constitute one and the same instrument.

     
  14.5.

No waiver by any Party, whether express or implied, of its rights under any provision of this Agreement shall constitute a waiver of such Party's rights under such provisions at any other time or a waiver of such party's rights under any other provision of this Agreement. No failure by any Party to take any action against any breach of this Agreement or default by the other Party hereto shall constitute a waiver of the former Party's rights to enforce any provision of this Agreement or to take action against such breach or default or any subsequent breach or default by such other Party.

     
  14.6.

If any provision of this Agreement is held to be unenforceable under applicable law, then such provision shall be modified as set out below and the balance of this Agreement shall be interpreted as if such provision were so modified and shall be enforceable in accordance with its terms. The Parties shall negotiate in good faith in order to agree on the terms of an alternative provision which complies with applicable law and achieves, to the greatest extent possible, the same effect as would have been achieved by the invalid or unenforceable provision.



  -14-  


  14.7.

Nothing contained in this Agreement shall be construed to place the parties in a relationship of partners or parties to a joint venture or to constitute either Party an agent, employee or a legal representative of the other Party and neither Party shall have power or authority to act on behalf of the other Party or to bind the other Party in any manner whatsoever.

WHEREOF the Parties have caused this Agreement to be executed by their duly authorized representatives as of this           18th          day of            June                , 2018.


Attachments:

Exhibit A – Product Specifications.
Exhibit B - Development Plan (including Project Budget)
Exhibit C- Mircod Background Patents

-15-


EX-31.1 3 exhibit31-1.htm EXHIBIT 31.1 Orgenesis Inc.: Exhibit 31.1 - Filed by newsfilecorp.com

Exhibit 31.1

ORGENESIS INC.
CERTIFICATION PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Vered Caplan, certify that:

1.

I have reviewed this quarterly report on Form 10-Q for the quarter ended August 31, 2018 of Orgenesis Inc.;

   
2.

Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, considering the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

   
3.

Based on my knowledge, the financial statements, and other financial information included in this report, present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

   
4.

The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a–15(e) and 15d–15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a–15(f) and 15d–15(f)) for the registrant and have:


  (a)

designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under the Company’s supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to the Company by others within those entities, particularly during the period in which this report is being prepared;

     
  (b)

designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under the Company’s supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

     
  (c)

evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report the Company’s conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

     
  (d)

disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and


5.

The registrant’s other certifying officer and I have disclosed, based on the Company’s most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):


  (a)

all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

     
  (b)

any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.


By:
 
/s/ Vered Caplan
Vered Caplan
President & Chief Executive Officer
(Principal Executive Officer)
Date: October 12, 2018


EX-31.2 4 exhibit31-2.htm EXHIBIT 31.2 Orgenesis Inc.: Exhibit 31.2 - Filed by newsfilecorp.com

Exhibit 31.2

ORGENESIS INC.
CERTIFICATION PURSUANT TO SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Neil Reithinger, certify that:

1.

I have reviewed this quarterly report on Form 10-Q for the quarter ended August 31, 2018 of Orgenesis Inc.;

   
2.

Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

   
3.

Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

   
4.

The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a–15(e) and 15d–15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a–15(f) and 15d–15(f)) for the registrant and have:


  (a)

designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under the Company’s supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to the Company by others within those entities, particularly during the period in which this report is being prepared;

     
  (b)

designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under the Company’s supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

     
  (c)

evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report the Company’s conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

     
  (d)

disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and


5.

The registrant’s other certifying officer and I have disclosed, based on the Company’s most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):


  (a)

all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

     
  (b)

any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.


By:
 
/s/ Neil Reithinger
Neil Reithinger
Chief Financial Officer, Treasurer and Secretary
(Principal Financial Officer and Principal Accounting Officer)
Date: October 12, 2018


EX-32.1 5 exhibit32-1.htm EXHIBIT 32.1 Orgenesis Inc.: Exhibit 32.1 - Filed by newsfilecorp.com

Exhibit 32.1

ORGENESIS INC.
CERTIFICATION PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

The undersigned, Vered Caplan, hereby certifies, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(a)

The quarterly report on Form 10-Q of Orgenesis Inc. for the quarter ended August 31, 2018 fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

   
(b)

Information contained in the Form 10-Q fairly presents, in all material respects, the financial condition and results of operations of Orgenesis Inc.


By:
 
/s/ Vered Caplan
Vered Caplan
President & Chief Executive Officer
(Principal Executive Officer)
Date: October 12, 2018


EX-32.2 6 exhibit32-2.htm EXHIBIT 32.2 Orgenesis Inc.: Exhibit 32.2 - Filed by newsfilecorp.com

Exhibit 32.2

ORGENESIS INC.
CERTIFICATION PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

The undersigned, Neil Reithinger, hereby certifies, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(a)

The quarterly report on Form 10-Q of Orgenesis Inc. for the quarter ended August 31, 2018 fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

   
(b)

Information contained in the Form 10-Q fairly presents, in all material respects, the financial condition and results of operations of Orgenesis Inc.


By:
 
/s/ Neil Reithinger
Neil Reithinger
Chief Financial Officer, Treasurer and Secretary
(Principal Financial Officer and Principal Accounting Officer)
Date: October 12, 2018


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4350000 13819000 -529000 -201000 400000 3519000 891000 17137000 762000 7511000 106000 813000 0 <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <b>NOTE 1 - GENERAL AND BASIS OF PRESENTATION</b> </p> <table border="0" cellpadding="0" cellspacing="0" style="border-color: black; font-size: 10pt; border-collapse: collapse; font-family: times,serif;" width="100%"> <tr> <td valign="top" width="5%"> <i>a.</i> </td> <td> <p align="justify" style="font-family: times,serif; font-size: 10pt; margin: inherit;"> <i>General</i> </p> </td> </tr> </table> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">Orgenesis Inc., a Nevada corporation (&#8220;Orgenesis&#8221; or the &#8220;Company&#8221;), is a service and research company in the field of the regenerative medicine industry with a focus on cell therapy development and manufacturing for advanced medicinal products. In addition, the Company is focused on developing novel and proprietary cell therapy trans-differentiation technologies for the treatment of diabetes. The consolidated financial statements include the accounts of Orgenesis Inc. and its subsidiaries, including those of the Masthercell Global group, a contract development and manufacturing organization, or CDMO, specializing in cell therapy development and manufacturing for advanced medicinal products in the USA, Belgium, Korea and Israel (See Note 4 for explanation that during the third fiscal quarter that the Company gained control of Atvio and CureCell); Orgenesis SPRL (the &#8220;Belgian Subsidiary&#8221;), a Belgian-based subsidiary which is engaged in development and manufacturing activities together with clinical development studies in Europe; Orgenesis Maryland Inc. (the &#8220;U.S. Subsidiary&#8221;), a Maryland corporation; and Orgenesis Ltd., an Israeli corporation, (the &#8220;Israeli Subsidiary&#8221;).</p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">The Company&#8217;s goal is to industrialize cell therapy for fast, safe and cost-effective production in order to provide rapid therapies for any market around the world through a world-wide network of CDMO joint venture partners. The Company&#8217;s trans-differentiation technologies for treating diabetes, which will be referred to as the cellular therapy (&#8220;CT&#8221;) business, is based on a technology licensed by Tel Hashomer Medical Research (&#8220;THM&#8221;) to the Israeli Subsidiary that demonstrates the capacity to induce a shift in the developmental fate of cells from the liver and trans-differentiating (converting) them into &#8220;pancreatic beta cell-like&#8221; insulin-producing cells.</p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">As used in this report and unless otherwise indicated, the term &#8220;Company&#8221; refers to Orgenesis Inc. and its subsidiaries (&#8220;Subsidiaries&#8221;). Unless otherwise specified, all amounts are expressed in United States Dollars.</p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> On November 16, 2017, the Company implemented a reverse stock split of its outstanding shares of common stock at a ratio of 1 -for- 12 shares. The reverse stock split has been reflected in these condensed consolidated financial statements. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">On March 13, 2018, the Company's common stock began to be listed and traded on the Nasdaq Capital Market under the symbol &#8220;ORGS.&#8221;</p> <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <b>Consolidation of CDMO Entities and Strategic Funding</b> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> On June 28, 2018, the Company, Masthercell Global Inc. (a newly formed Delaware subsidiary of Orgenesis Inc being the Company that holds the Company&#8217;s CDMO business (&#8220;Masthercell Global&#8221;)), Great Point Partners, LLC, a manager of private equity funds focused on growing small to medium sized heath care companies (&#8220;Great Point&#8221;), and certain of Great Point&#8217;s affiliates, entered into a series of definitive strategic agreements intended to finance, strengthen and expand Orgenesis&#8217; CDMO business. In connection therewith, the Company, Masthercell Global and GPP-II Masthercell, LLC, a Delaware limited liability company (&#8220;GPP-II&#8221;) and an affiliate of Great Point entered into Stock Purchase agreement (the &#8220;SPA&#8221;) pursuant to which GPP-II purchased 378,000 shares of newly designated Series A Preferred Stock of Masthercell Global (the &#8220;Masthercell Global Preferred Stock&#8221;), representing 37.8% of the issued and outstanding share capital of Masthercell Global, for cash consideration to be paid into Masthercell Global of up to $25 million, of which $13.2 million is subject to certain contingencies described below (the &#8220;Consideration&#8221;). Orgenesis holds 622,000 shares of Masthercell Global&#8217;s Common Stock, representing 62.2% of the issued and outstanding equity share capital of Masthercell Global. An initial cash payment of $11.8 million of the Consideration was remitted at closing by GPP-II to Masthercell Global. $1.5 Million of the initial capital contributed to Masthercell Global was used to reimburse the Investors for their fees and expenses incurred in conjunction with this transaction. The $1.5 million will reflect the entire fee payable under this transaction (net payment of $10.3 million). The follow up payment will be in the amount of $6,600,000 to be made in each of years 2018 and 2019 (the &#8220;Future Payments&#8221;), or an aggregate of $13.2 million, if (a) Masthercell Global achieves specified EBITDA and revenues targets during each of these years, and (b) the Orgenesis&#8217; shareholders approve on or before December 31, 2019 certain provisions of the Stockholders&#8217; Agreement entered into by these parties. None of the future Consideration amounts, if any, will result in an increase in GPP-II&#8217;s equity holdings in Masthercell Global beyond the 378,000 shares of Series A Preferred Stock issued to GPP-II at closing. Notwithstanding the foregoing, GPP-II may, in its sole discretion, elect to pay all or a portion of the future Consideration amounts even if the financial targets described above have not been achieved and the Orgenesis Stockholder Approval has not been obtained. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> In connection with the entry into the SPA described above, each of the Company, Masthercell Global and GPP-II entered into the Masthercell Global Inc. Stockholders&#8217; Agreement (the &#8220;Stockholders&#8217; Agreement&#8221;) providing for certain restrictions on the disposition of Masthercell Global securities, the provisions of certain options and rights with respect to the management and operations of Masthercell Global, certain rights to GPP-II (including, without limitation, a tag along right, drag along right and certain protective provisions). After the earlier of the second anniversary of the closing or certain enumerated circumstances, GPP-II is entitled to effectuate a spinoff of Masthercell Global and the Masthercell Global Subsidiaries (the &#8220;Spinoff&#8221;).&#160; The Spinoff is required to reflect a market value determined by one of the top ten independent accounting firms in the U.S. selected by GPP, provided that under certain conditions, such market valuation shall reflect a valuation of Masthercell Global and the Masthercell Global Subsidiaries of at least $50 million. In addition, upon certain enumerated events described below, GPP-II is entitled, at its option, to put to the Company (or, at Company&#8217;s discretion, to Masthercell Global if Masthercell Global shall then have the funds available to consummate the transaction) its shares in Masthercell Global or, alternatively, purchase from the Company its share capital in Masthercell Global at a purchase price equal to the fair market value of such equity holdings provided that the purchase price shall not be greater than three times the price per share of Masthercell Global Preferred Stock paid by GPP-II and shall not be less than the price per share of Masthercell Global Preferred Stock paid by GPP-II. GPP-II may exercise its put or call option upon the occurrence of any of the following: (i) there is an Activist Shareholder of the Company; (ii) the Chief Executive Officer and/or Chairman of the board of directors of the Company resigns or is replaced, removed, or terminated for any reason prior to June 28, 2023; (iii) there is a Change of Control event of the Company; or (iv) the industry expert director appointed to the board of directors of Masthercell Global is removed or replaced (or a new such director is appointed) without the prior written consent of GPP-II. For the purposes of the foregoing, the following definitions shall apply: (A) &#8220;Activist Shareholder&#8221; shall mean any Person who acquires shares of capital stock of the Company who either: (x) acquires more than a majority of the voting power of the Company, (y) actively takes over and controls a majority of the board of directors of the Company, or (z) is required to file a Schedule 13D with respect to such Person&#8217;s ownership of the Company and has described a plan, proposal or intent to take action with respect to exerting significant pressure on the management of or directors of, the Company; and (B) &#8220;Change of Control&#8221; shall mean any of: (a) the acquisition, directly or indirectly (in a single transaction or a series of related transactions) by a Person or group of Persons of either (I) a majority of the common stock of the Company (whether by merger, consolidation, stock purchase, tender offer, reorganization, recapitalization or otherwise), or (II) all or substantially all of the assets of the Company and its Subsidiaries (but only if such transaction includes the transfer of Securities held by the Company), (b) if any four (4) of the directors of the Company as of June 28, 2018 are removed or replaced or for any other reason cease to serve as directors of the Company, (c) the filing of a petition in bankruptcy or the commencement of any proceedings under bankruptcy laws by or against the Company, provided that such filing or commencement shall be deemed a Change of Control immediately if filed or commenced by the Company or after sixty (60) days if such filing is initiated by a creditor of the Company and is not dismissed; (d) insolvency of the Company that is not cured by the Company within thirty (30) days; (e) the appointment of a receiver for the Company, provided that such appointment shall constitute an Change of Control immediately if the appointment was consented to by the Company or after sixty (60) days if not consented to by the Company and such appointment is not terminated; or (f) or dissolution of the Company. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> The Stockholders&#8217; Agreement further provides that GPP-II is entitled, at any time, to convert its share capital in Masthercell Global for the Company&#8217;s common stock in an amount equal to the lesser of (a)(i) the fair market value of GPP-II&#8217;s shares of Masthercell Global Preferred Stock to be exchanged, divided by (ii) the average closing price per share of Orgenesis Common Stock during the thirty (30) day period ending on the date that GPP-II provides the exchange notice (the &#8220;Exchange Price&#8221;) and (b)(i) the fair market value of GPP-II&#8217;s shares of Masthercell Global Preferred Stock to be exchanged assuming a value of Masthercell Global equal to three and a half (3.5) times the revenue of Masthercell Global during the last twelve (12) complete calendar months immediately prior to the exchange divided by (ii) the Exchange Price; provided, that in no event will (A) the Exchange Price be less than a price per share that would result in Orgenesis having an enterprise value of less than $250,000,000 and (B) the maximum number of shares of Orgenesis Common Stock to be issued shall not exceed 2,704,247 shares of outstanding Orgenesis Common Stock (representing approximately 19.99% of then outstanding Orgenesis Common Stock), unless Orgenesis obtains shareholder approval for the issuance of such greater amount of shares of Orgenesis Common Stock in accordance with the rules and regulations of the Nasdaq Stock Market. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> Great Point and Masthercell Global entered into an advisory services agreement pursuant to which Great Point is to provide management services to Masthercell Global for which Great Point will be compensated at an annual base compensation equal to the greater of (i) $250,000 per each 12 month period or (ii) 5% of the EBITDA for such 12 month period, payable in arrears in quarterly installments; provided, that these payments will (A) begin to accrue immediately, but shall not be paid in cash to Great Point until such time as Masthercell Global generates EBITDA of at least $2,000,000 for any 12 month period or the sale of or change in control of Masthercell Global, and (B) shall not exceed an aggregate annual amount of $500,000. Such compensation accrues but is not owed to Great Point until the earlier of (i) Masthercell Global generating EBITDA of at least $2 million for any 12 months period following the date of the agreement or (ii) a Sale of the Company or Change of Control of the Company (as both terms are defined therein). </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> GPP Securities, LLC, a Delaware limited liability company and an affiliate of Great Point and Masthercell Global entered into a transaction services agreement pursuant to which GPP Securities, LLC is to provide certain brokerage services to Masthercell Global for which GPP Securities LLC will be entitled to a certain Exit Fee and Transaction Fee (as both terms are defined in the agreement), such fees not to be less than 2 percent of the applicable transaction value. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">The Company accounted for the investment made by GPP as a redeemable non-controlling interest due to the embedded redemption feature whose settlement is not at the Company discretion.</p> <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <b>Corporate Reorganization</b> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">Contemporaneous with the execution of the SPA and the Stockholders&#8217; Agreement, Orgenesis and Masthercell Global entered into a Contribution, Assignment and Assumption Agreement pursuant to which Orgenesis contributed to Masthercell Global assets relating to the CDMO Business (as defined below), including the CDMO subsidiaries (the &#8220;Corporate Reorganization&#8221;). For further details see Note 4. Together with MaSTherCell S.A., Atvio and CureCell are directly held subsidiaries under Masthercell Global (collectively, the &#8220;Masthercell Global Subsidiaries&#8221;).</p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">Masthercell Global, through the Masthercell Global Subsidiaries, will be engaged in the business of providing manufacturing and development services to third parties related to cell therapy products, and the creation and development of technology, and optimizations in connection with such manufacturing and development services for third parties (the &#8220;CDMO Business&#8221;). Under the terms of the Stockholders&#8217; Agreement, Orgenesis has agreed that so long as it owns equity in Masthercell Global and for two years thereafter it will not engage in the CDMO Business, except through Masthercell Global (but may continue to engage in its other areas of business). In addition, except for certain limited circumstances, each of Orgenesis and GPP-II agreed in the Stockholders&#8217; Agreement to not recruit or solicit or hire any officer or employee of Masthercell Global that was or is involved in the CDMO Business.</p> <table border="0" cellpadding="0" cellspacing="0" style="border-color: black; font-size: 10pt; border-collapse: collapse; font-family: times,serif;" width="100%"> <tr> <td valign="top" width="5%"> <i>b.</i> </td> <td> <p align="justify" style="font-family: times,serif; font-size: 10pt; margin: inherit;"> <i>Liquidity</i> </p> </td> </tr> </table> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> As of August 31, 2018, the Company accumulated losses of approximately $57.4 million. Although the Company is showing positive revenue and gross profit trends in its CDMO business, the Company expects to incur further losses in the CT business. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> To date, the Company has been funding operations primarily from the proceeds from private placements of the Company&#8217;s convertible debt and equity securities and from revenues generated by MaSTherCell S.A. From December 1, 2017 through August 31, 2018, the Company received, through MaSTherCell S.A., proceeds of approximately $11.5 million in revenues and accounts receivable from customers, and $16.5 million from the private placement to accredited investors of the Company's equity and equity linked securities and convertible loans and exercise of warrants, out of which $8.1 million are from the institutional investor with whom the Company entered into definitive agreements in January 2017 for the private placement of units (see also Note 7(a)).&#160; In addition, from September 1, 2018 through October 12, 2018, the Company raised $3.4 million from the private placement referred to above of unsubscribed units under such investor&#8217;s subscription agreement, and proceeds of approximately $2.9 million in accounts receivable from customers of MaSTherCell S.A. See also Note 12. </p> <table border="0" cellpadding="0" cellspacing="0" style="border-color: black; font-size: 10pt; border-collapse: collapse; font-family: times,serif;" width="100%"> <tr> <td valign="top" width="5%"> <i>c.</i> </td> <td> <p align="justify" style="font-family: times,serif; font-size: 10pt; margin: inherit;"> <i>Basis of Presentation</i> </p> </td> </tr> </table> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">These unaudited condensed consolidated financial statements of the Company have been prepared in accordance with U.S. GAAP, pursuant to the rules and regulations of the United States Securities and Exchange Commission (&#8220;SEC&#8221;) for interim financial statements. Accordingly, they do not contain all information and notes required by U.S. GAAP for annual financial statements. In the opinion of management, the unaudited condensed consolidated interim financial statements reflect all adjustments, which include normal recurring adjustments, necessary for a fair statement of the Company&#8217;s consolidated financial position as of August 31, 2018, and the consolidated statements of comprehensive loss for the three and nine months ended August 31, 2018 and 2017, and the changes in equity and cash flows for the nine-month period ended August 31, 2018 and 2017. The interim results are not necessarily indicative of the results to be expected for the year ending November 30, 2018. These unaudited interim condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and notes thereto included in the Company&#8217;s Annual Report on Form 10-K for the year ended November 30, 2017.</p> <table border="0" cellpadding="0" cellspacing="0" style="border-color: black; font-size: 10pt; border-collapse: collapse; font-family: times,serif;" width="100%"> <tr> <td valign="top" width="5%"> <i>d.</i> </td> <td> <p align="justify" style="font-family: times,serif; font-size: 10pt; margin: inherit;"> <i>Collaboration and Joint Venture Agreements</i> </p> </td> </tr> </table> <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <b>Mircod Limited</b> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> On June 19, 2018, the Company and Mircod Limited, a company formed under the laws of Cyprus (&#8220;Mircod&#8221;) entered into a Collaboration and License Agreement (the &#8220;Collaboration Agreement&#8221;) for the research, development and commercialization of potential key technologies related to biological sensing for the Company's clinical development and manufacturing projects (the &#8220;Development Project&#8221;). Within 45 days of the execution of the Collaboration Agreement, the parties are to approve a written project development plan outlining each party&#8217;s responsibilities with respect to the Development Project, and the Company will be funding the projected development costs as outlined in the development plan. Under the terms of the Collaboration Agreement, the Company remitted to Mircod an upfront payment of $50,000. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> Under the Collaboration Agreement, all results of such collaboration (&#8220;Project Results&#8221;) shall be jointly owned by Mircod and the Company. The Company was granted an exclusive, worldwide sub licensable license under Mircod&#8217;s right in such Project Results to use and commercialize Project Results in consideration for a royalty of 5% of Net Sales (as defined in the Collaboration Agreement) of products incorporating Project Results. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> Subject to completion of the Development Project, Mircod and the Company are to negotiate and enter into a manufacturing and supply agreement under which Mircod is to manufacture and supply products incorporating the Project Results and, at the Company&#8217;s request, to provide support and maintenance service for such products. If for whatever reason the parties fail to enter into such manufacturing and supply agreement within 90 days of the completion of the Development Project or if Mircod is unable to perform such services, the Company is entitled to manufacture the products, in which event Mircod will be entitled to a payment of $80,000 and royalties on Net Sales are to increase to 8% of Net Sales. </p> <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <b>HekaBio K.K</b> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> On July 10, 2018, the Company and HekaBio K.K. (&#8220;HB&#8221;), a corporation organized under the laws of Japan entered into a Joint Venture Agreement (the &#8220;JVA&#8221;) pursuant to which the parties will collaborate in the clinical development and commercialization of regeneration and cell and gene therapeutic products (hereinafter the &#8220;Products&#8221;) in Japan (the &#8220;Project&#8221;). The parties intend to pursue the joint venture through a newly established Japanese company (hereinafter the &#8220;JV Company&#8221;) which the Company by itself, or together with a designee, will hold a 49% participating interest therein, with the remaining 51% participating interest being held by HB. HB will fund, at its sole expense, all costs associated with obtaining the requisite regulatory approvals for conducting clinical trials, as well as performing all clinical and other testing required for market authorization of the Products in Japan. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> Under the JVA, each party may invest up to $10 million, which may take the form of a loan, if required, as determined by the steering committee. The terms of such investment, if any, will be on terms mutually agreeable to the parties, provided that the minimum pre-money valuation for any such investment shall not be less than $10 million. Additionally, HB was granted an option to affect an equity investment in the Company of up to $15 million within the next 12 months on mutually agreeable terms. If such investment is in fact consummated, the Company agreed to invest in the JV Company by way of a convertible loan an amount to HB&#8217;s pro-rata participating interest in the JV Company, which initially will be at 51%. Such loan may then be converted by the Company into share capital of the JV company at an agreed upon formula for determining JV Company valuation which in no event shall be less than $10 million. Under the JVA, the Company can require HB to sell to the Company its participating (including equity) interest in the JV Company in consideration for the issuance of the Company&#8217;s common stock based on an agreed upon formula for determining JV Company valuation which in no event shall be less than $10 million. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> In addition, under the JVA, the Company shall grant the JV Company an exclusive license to certain intellectual property of the Company as may be required for the JV Company to develop and commercialize the Products in Japan. In consideration of such license, the JV Company shall pay the Company, in addition to other payments, royalties at the rate of 10% of the JV Company&#8217;s net sales of Products. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">It was further agreed that the JV Company shall grant the Company (and its affiliates) a non-exclusive, worldwide (other than Japan), royalty-free and fully paid-up license to use and practice, for any purpose, new inventions, discoveries and intellectual property rights that are generated by and/or on behalf of HB and/or the JV Company in connection with the Project.</p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">All matters pertaining to such license rights shall be governed under a separate license agreement to be entered by and between the Company and the JV Company.</p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">As of August 31, 2018, no activity had begun in the said JV and no investments were made therein.</p> <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <b>Image Securities Ltd.</b> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">On July 11, 2018, the Company and Image Securities Ltd., a corporation with its registered office in Grand Cayman, Grand Cayman Islands (&#8220;India Partner&#8221;) entered into a Joint Venture Agreement (the &#8220;India JVA&#8221;) pursuant to which the parties will collaborate in the development and/or marketing, clinical development and commercialization of cell therapy products in India (the &#8220;Cell Therapy Products&#8221;). The India Partner will collaborate with a network of healthcare facilities and a healthcare infrastructure as well as financial partners to advance the development and commercialization of the cell therapy products.</p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> The India JVA becomes effective upon the consummation of an equity investment by the India partner in the Company of $5 million within 15 days of the execution of the India JVA through the purchase of units of Orgenesis securities at a per unit purchase price payable into the Company of $6.24, with each unit comprised of one share of the Company and three-year warrant for the acquisition of an additional common share at a per share exercise price of $6.24. Subject to the consummation of such equity investment in the Company, the Company is to advance to the JV Company a convertible loan in the amount of $5 million. The loan is convertible into equity capital of the JV Company at an agreed upon formula for determining JV Company valuation. The investment in the Company by the India Partner would be the consummation of the previously disclosed private placement subscription agreement entered into in December 2016 between the Company and an affiliate of the India Partner pursuant to which the closing of such subscription agreement was by the terms thereof delayed until terms comprising the India JV were mutually agreed to. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> Under the India JVA, the India Partner agreed to invest in the JV $10 million within 12 months of the incorporation of the JV Company. If for whatever reason such investment is not made by the India Partner within such time, then Orgenesis is authorized to convert its above-referenced loan into 50% of the equity capital of the JV Company on a fully diluted basis, provided that if the pre-money valuation of the JV Company is then independently determined to be less than $5 million, then such conversion to be effected in the basis of such valuation. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">As of August 31, 2018, no activity had begun in the said JV and no investments were made therein.</p> 1 12 378000 0.378 25000000 13200000 622000 0.622 11800000 1500000 1500000 10300000 6600000 13200000 378000 50000000 -3.5 250000000 2704247 0.1999 250000 12 0.05 12 2000000 12 500000 2000000 12 0.02 57400000 11500000 16500000 8100000 3400000 2900000 45 50000 0.05 90 80000 0.08 0.49 0.51 10000000 10000000 15000000 12 0.51 10000000 10000000 0.10 5000000 15 6.24 6.24 5000000 10000000 12 0.50 5000000 <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <b>NOTE 2 - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES</b> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">The accounting policies adopted are consistent with those of the previous financial year, except as noted below regarding the adoption of new accounting pronouncements.</p> <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <i>Recently Issued Accounting Pronouncements- adopted by the Company</i> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">1) &#160;&#160; In November 2016, the FASB issuedASU 2016-18, Statement of Cash Flows (Topic 230): Restricted Cash (a Consensus of the FASB Emerging Issues Task Force) (&#8220;ASU 2016-18&#8221;), which requires entities to include amounts generally described as restricted cash and restricted cash equivalents in cash and cash equivalents when reconciling beginning-of-period and end-of-period total amounts shown on the statement of cash flows. 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width="2%">&#160;</td> <td align="left" bgcolor="#e6efff" valign="bottom" width="1%">$</td> <td align="right" bgcolor="#e6efff" valign="bottom" width="9%"> 3,940 </td> <td align="left" bgcolor="#e6efff" valign="bottom" width="2%">&#160;</td> </tr> </table> -1488000 -1046000 -2534000 2032000 -1987000 45000 -11018000 -1046000 -12064000 -1532000 -1987000 -3519000 -11511000 -1046000 -12557000 -1953000 -1987000 -3940000 <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <b>NOTE 3 - SEGMENT INFORMATION</b> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">The Chief Executive Officer ("CEO") is the Company&#8217;s chief operating decision-maker ("CODM").</p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">Based on the Company's organizational structure, its business activities and information reviewed by the CODM for the purposes of allocating resources and assessing performance, management has determined that there are two operating segments.</p> <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <i> <u>CDMO</u> </i> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">The CDMO activity is comprised of a specialization in cell therapy development for advanced therapeutic products and is comprised of two types of services to its customers: (i) process and assay development services and (ii) cGMP contract manufacturing services. The CDMO activities include the operations of Masthercell Global since the Corporate Reorganization (which includes the operations of CureCell and Atvio from the same date) and MaSTherCell prior to the Corporate Reorganization. As of the date of acquisition of CureCell and Atvio their activity is included in this segment.</p> <p align="justify" style="font-family: times,serif; font-size: 10pt;"> <i> <u>CT Business</u> </i> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">The CT Business activity is based on our technology that demonstrates the capacity to induce a shift in the developmental fate of cells from the liver and differentiating (converting) them into &#8220;pancreatic beta cell-like&#8221; insulin producing cells for patients with Type 1 Diabetes. 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In furtherance thereof, Masthercell Global, as Orgenesis&#8217; assignee, acquired all of the issued and outstanding share capital of Atvio, the Company&#8217;s Israel based CDMO partner since August 2016, and 94.2% of the share capital of CureCell, the Company&#8217;s Korea based CDMO partner since March 2016. Orgenesis exercised the "call option" to which it was entitled under the joint venture agreements with each of these entities to purchase from the former shareholders their equity holding. The consideration for the outstanding share equity in each of Atvio and CureCell consisted solely of Company Common Stock. In respect of the acquisition of Atvio, the Company issued to the former Atvio shareholders an aggregate of 83,964 shares of Company Common Stock. In respect of the acquisition of CureCell, the Company will issue according to valuation to the former CureCell shareholders an aggregate of 202,846 shares of Company Common Stock. Together with MaSTherCell S.A., Atvio and CureCell are directly held subsidiaries under Masthercell Global. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">CureCell and Atvio are customer-oriented CDMO companies specializing in cell therapy development for advanced medicinal products.</p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> The exercise of the call options of CureCell and Atvio, pursuant to which the Company obtained effective control over such entities, was accounted for as a business combination. The results of operations of CureCell and Atvio have been included in the Company&#8217;s condensed consolidated statements of operations starting from June 28, 2018, the date on which the Company obtained effective control of CureCell and Atvio. 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font-size: 10pt;"> <b>NOTE 5 &#8211; CONVERTIBLE LOAN AGREEMENTS</b> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> (a)&#160;&#160;&#160; &#160;&#160; During the nine months ended August 31, 2018, the Company entered into several unsecured convertible loan agreements with accredited or offshore investors for an aggregate amount of $720 thousand. 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There is a significant disagreement between the Company and these two entities as to the number of shares of Common Stock issuable to these entities, and they contend that the number of shares of Common Stock issuable to them should not consider the reverse stock split. The Company rejects these contentions in their entirety and, based on the advice of specially retained counsel, believes that these claims are without legal merit and not made in good faith. The Company intends to vigorously defend its interests and pursue other avenues of legal address. Through its counsel, the Company has advised these entities that unless they withdraw their request within a specified period, the Company will cancel the above referenced agreements and these parties&#8217; right to receive any shares of the Company&#8217;s Common Stock. 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(&#8220;Adva&#8221;), entered into a Master Services Agreement (&#8220;MSA&#8221;), under which the Company and/or its affiliates are to provide certain services relating to development of products to Adva, as may be agreed between the parties from time to time. Under the MSA, the Company undertook to provide Adva with in kind funding in the form of materials and services having an aggregate value of $749,900 at the Company&#8217;s own cost in accordance with a project schedule and related mutually acceptable project budget. The Company entered into agreement with Atvio Biotech Ltd, its Israeli-based joint venture, to fulfill its obligations pursuant this MSA. As of August 31, 2018, the Company incurred a total expense of $282 thousand. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> In consideration for and subject to the fulfillment by the Company of such in-kind funding commitment, Adva agreed that upon completion of the development of the products, the Company and/or its affiliates and Adva shall enter into a supply agreement pursuant to which for a period of eight (8) years following execution of such supply agreement, the Company and/or its affiliates (as applicable) is entitled (on a non-exclusive basis) to purchase the products from Adva at a specified discount pricing from their then standard pricing. The Company and/or its affiliates were also granted a non-exclusive worldwide right to distribute such products, directly or through any of their respective contract development and manufacturing organization (CDMO) service centers during such term. 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The subscription proceeds were payable on a periodic basis through September 2018. The Company subsequently agreed to delay the payments until October 15, 2018. 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style="text-indent: 5%; font-family: times,serif; font-size: 10pt;">The fair value of these option grants is based on the following assumptions:</p> <div align="center"> <table border="0" cellpadding="0" cellspacing="0" style="border-color: black; font-size: 10pt; border-collapse: collapse; font-family: times,serif;" width="50%"> <tr valign="top"> <td align="left">&#160;</td> <td align="center" width="30%"> <b>Nine Months Ended</b> </td> </tr> <tr valign="top"> <td align="left">&#160;</td> <td align="center" width="30%"> <b> <u>August 31, 2018</u> </b> </td> </tr> <tr valign="top"> <td align="left" bgcolor="#e6efff">Value of one common share</td> <td align="center" bgcolor="#e6efff" width="30%"> $8.3,$4.42 </td> </tr> <tr valign="top"> <td align="left">Dividend yield</td> <td align="center" width="30%"> 0% </td> </tr> <tr valign="top"> <td align="left" bgcolor="#e6efff">Expected stock price volatility</td> <td align="center" bgcolor="#e6efff" width="30%"> 91%- 98% </td> </tr> <tr valign="top"> <td align="left">Risk free interest rate</td> <td align="center" width="30%"> $2.33 -$2.83 </td> </tr> <tr valign="top"> <td align="left" bgcolor="#e6efff">Expected term (years)</td> <td align="center" bgcolor="#e6efff" width="30%"> 4.5 - 10 </td> </tr> </table> </div> <br/> <table border="0" cellpadding="0" cellspacing="0" style="border-color: black; font-size: 10pt; border-collapse: collapse; font-family: times,serif;" width="100%"> <tr> <td valign="top" width="5%"> <i>c.</i> </td> <td> <p align="justify" style="font-family: times,serif; font-size: 10pt; margin: inherit;"> <i>Shares and Warrants Granted to non-employees</i> </p> </td> </tr> </table> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> 1) &#160;&#160; During the nine months ended August 31, 2018, the Company granted to several consultants 50,938 warrants with each exercisable at $6.24 to $15.41 per share for three years as a success fee with respect to the issuance of the convertible loans and part of the private placement. The fair value of those warrants as of the date of grant using the Black-Scholes valuation model was $248 thousand. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> 2) &#160;&#160; In December 2017, the Company entered into investor relations services, marketing and related services agreement. Under the terms of the agreement, the Company agreed to grant the consultant 100,000 shares of restricted common stock, out of which the first 25,000 shares will vest after 30 days from the signing date, and 75,000 shares are to vest monthly over 15 months commencing February 2018. As of August 31, 2018, 60,000 shares were vested. The fair value of the shares as of the date of grant was $738 thousand. </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> 3) &#160;&#160; In December 2017, the Company entered into an investor relations services, marketing and related services agreement. 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The fair value of the units as of the date of grant was $171 thousand, out of which $62 thousand reflect the fair value of the warrants using the Black-Scholes valuation model. In July 2018, the board approved an additional issuance of 6,629 shares and three-year warrants to purchase up to 6,629 shares of the Company&#8217;s Common Stock at a per share exercise price of $6.24. 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font-size: 10pt;"> <b>NOTE 12 - SUBSEQUENT EVENTS</b> </p> <p align="justify" style="text-indent: 5%; font-family: times,serif; font-size: 10pt;"> In October 2018, the Company raised $3.4 million from the institutional investor referred to in Note 7 entitling such investor to 550,481 shares of Common Stock and three-year warrants for an additional 550,481 shares. 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Presentation 59 General And Basis Of Presentation 59 General And Basis Of Presentation 60 General And Basis Of Presentation 60 General And Basis Of Presentation 61 General And Basis Of Presentation 61 Products and Services [Axis] Products and Services [Domain] Services [Member] Services [Member] Goods sold [Member] Revenues Exercise Of Call Options Of Curecell And Atvio 1 Exercise Of Call Options Of Curecell And Atvio 1 Exercise Of Call Options Of Curecell And Atvio 2 Exercise Of Call Options Of Curecell And Atvio 2 Exercise Of Call Options Of Curecell And Atvio 3 Exercise Of Call Options Of Curecell And Atvio 3 Exercise Of Call Options Of Curecell And Atvio 4 Exercise Of Call Options Of Curecell And Atvio 4 Exercise Of Call Options Of Curecell And Atvio 5 Exercise Of Call Options Of Curecell And Atvio 5 Exercise Of Call Options Of Curecell And Atvio 6 Exercise Of Call Options Of Curecell And Atvio 6 Exercise Of Call Options Of Curecell And Atvio 7 Exercise Of Call Options Of Curecell And Atvio 7 Exercise Of Call Options Of Curecell And Atvio 8 Exercise Of Call Options Of Curecell And Atvio 8 Exercise Of Call Options Of Curecell And Atvio 9 Exercise Of Call Options Of Curecell And Atvio 9 Exercise Of Call Options Of Curecell And Atvio 10 Exercise Of Call Options Of Curecell And Atvio 10 Loans [Axis] Loans Loans [Domain] Loans Convertible loans outstanding from November 2014 and December 2016 [Member] Convertible loans outstanding from November 2014 and December 2016 Convertible loans outstanding from November 2014 [Member] Convertible loans outstanding from November 2014 Convertible loans outstanding from December 2016 [Member] Convertible loans outstanding from December 2016 Proceeds from issuance of convertible loans (net of transaction costs) Debt Instrument, Interest Rate, Stated Percentage Debt Instrument, Convertible, Conversion Price Class of Warrant or Right, Grants in Period, Net of Forfeitures Class of Warrant or Right, Grants in Period, Net of Forfeitures Class of Warrant or Right, Grants in Period, Exercise Price Class of Warrant or Right, Grants in Period, Exercise Price Debt Instrument, Convertible, Beneficial Conversion Feature Convertible Debt Transaction Cost Adjustment of Warrants Granted for Services Debt Conversion, Converted Instrument, Amount Debt Conversion, Converted Instrument and Accrued Interest, Amount Debt Conversion, Converted Instrument and Accrued Interest, Amount Debt Conversion, Converted Instrument, Shares Issued Debt Conversion, Converted Instrument, Warrants or Options Issued Revenue from grants [Member] Revenue from grants Commitment Expenses Grants Receivable, Noncurrent Equity transactions [Axis] Equity transactions Equity transactions [Domain] Equity transactions Definitive agreements with an institutional investor [Member] Definitive agreements with an institutional investor Definitive agreements with accredited and other qualified investors [Member] Definitive agreements with accredited and other qualified investors Range [Axis] Range [Domain] Minimum [Member] Maximum [Member] Units Issued During Period, Units Units Issued During Period, Units Common Stock Shares Subscriptions Units Issued During Period, Exercise Price Units Issued During Period, Exercise Price Proceeds from Issuance of Private Placement Stock Issued During Period, Shares, Issued for Cash Stock Issued During Period, Shares, Issued for Cash Stock Issued During Period, Value of Shares to be Allotted Stock Issued During Period, Value of Shares to be Allotted Stock Issuance, Fee Percentage Stock Issuance, Fee Percentage Payments of Transaction Costs Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures Cash Received From Subscription Cash Received From Subscription Warrants Granted During Period, Value Warrants Granted During Period, Value Stock Based Compensation 1 Stock Based Compensation 1 Stock Based Compensation 2 Stock Based Compensation 2 Stock Based Compensation 3 Stock Based Compensation 3 Stock Based Compensation 4 Stock Based Compensation 4 Stock Based Compensation 5 Stock Based Compensation 5 Stock Based Compensation 6 Stock Based Compensation 6 Stock Based Compensation 7 Stock Based Compensation 7 Stock Based Compensation 8 Stock Based Compensation 8 Stock Based Compensation 9 Stock Based Compensation 9 Stock Based Compensation 10 Stock Based Compensation 10 Stock Based Compensation 11 Stock Based Compensation 11 Stock Based Compensation 12 Stock Based Compensation 12 Stock Based Compensation 13 Stock Based Compensation 13 Stock Based Compensation 14 Stock Based Compensation 14 Stock Based Compensation 15 Stock Based Compensation 15 Stock Based Compensation 16 Stock Based Compensation 16 Stock Based Compensation 17 Stock Based Compensation 17 Stock Based Compensation 18 Stock Based Compensation 18 Stock Based Compensation 19 Stock Based Compensation 19 Stock Based Compensation 20 Stock Based Compensation 20 Stock Based Compensation 21 Stock Based Compensation 21 Stock Based Compensation 22 Stock Based Compensation 22 Stock Based Compensation 23 Stock Based Compensation 23 Stock Based Compensation 24 Stock Based Compensation 24 Stock Based Compensation 25 Stock Based Compensation 25 Stock Based Compensation 26 Stock Based Compensation 26 Stock Based Compensation 27 Stock Based Compensation 27 Stock Based Compensation 28 Stock Based Compensation 28 Stock Based Compensation 29 Stock Based Compensation 29 Stock Based Compensation 30 Stock Based Compensation 30 Stock Based Compensation 31 Stock Based Compensation 31 Stock Based Compensation 32 Stock Based Compensation 32 Stock Based Compensation 33 Stock Based Compensation 33 Antidilutive Securities [Axis] Antidilutive Securities, Name [Domain] Options and warrants [Member] Options and warrants Shares [Member] Shares Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Net gain on remeasurement of previously equity interest in Atvio and CureCell to acquisition date fair value Transaction expenses related to GPP agreement Subsequent Events 1 Subsequent Events 1 Subsequent Events 2 Subsequent Events 2 Subsequent Events 3 Subsequent Events 3 Subsequent Events 4 Subsequent Events 4 Subsequent Events 5 Subsequent Events 5 Additional paid-in capital Accumulated deficit Total equity Financial expenses, net Loss before income taxes Net loss Subsegments Consolidation Items [Axis] Subsegments Consolidation Items [Domain] CDMO [Member] The Contract Development and Manufacturing Organization CTB [Member] The Cellular Therapy Business Corporate and Eliminations [Member] Consolidated [Member] Cost of revenues Gross profit (loss) Research and development expenses, net Operating expenses Other Income (Expense) Operating profit (loss) Depreciation and amortization expense Segment Performance Segment Performance Segment Performance Stock-based compensation Stock-based compensation Acquisition costs Acquisition costs Financial income (expenses), net Transaction expenses related to GPP agreement Share in losses of associated companies Loss before income tax Customer [Axis] Customer [Domain] Customer A [Member] Customer A Customer B [Member] Customer B Customer C [Member] Customer C Customer D [Member] Customer D Customer E [Member] Customer E Customer F [Member] Customer F Revenues Consolidated Entities [Axis] Consolidated Entities [Domain] CureCell [Member] CureCell Cash and cash equivalents Property and equipment, net Inventory Other assets Other Intangible assets Goodwill Total assets Deferred income from the company and others Deferred taxes Fair value of convertible loan from the company Non-controlling interests Other liabilities Total liabilities Total consideration transferred Fair value according of shares issued Acquisition date fair value of previously held equity interest Warrants component Warrants component Price protection derivative component Price protection derivative component Shares component Shares component Total Total Value of one common share Dividend yield Expected stock price volatility Risk free interest rate Expected term (years) Warrants component Warrants component Price protection derivative component Price protection derivative component Shares component Shares component Total Total Class of Warrant or Right, Valuation Method, Value of one common share Class of Warrant or Right, Valuation Method, Value of one common share Class of Warrant or Right, Valuation Method, Expected Dividend Rate Class of Warrant or Right, Valuation Method, Expected Volatility Rate Class of Warrant or Right, Valuation Method, Risk Free Interest Rate Class of Warrant or Right, Valuation Method, Expected Term Options Granted to Directors [Member] Options Granted to Directors Employee (ranges) [Axis] Employee Ranges Employee (ranges) [Domain] Employee (ranges) Employee 1 [Member] Employee 1 Employee 2 [Member] Employee 2 Employee 3 [Member] Employee 3 MaSTherCell's Employees 1 [Member] MaSTherCell's Employees 1 MaSTherCell's Employees 2 [Member] MaSTherCell's Employees 2 Employee 4 [Member] Employee 4 No. of options granted Exercise price Vesting period Vesting period Fair value at grant Fair value at grant Expiration period Expiration period Non-employee (ranges) [Axis] Non-employee (ranges) Non employee (ranges) [Domain] Non employee (ranges) Non-employee 1 [Member] Non-employee 1 Non-employee 2 [Member] Non-employee 2 Non-employee 3 [Member] Non-employee 3 Value of one common share Dividend yield Expected stock price volatility Risk free interest rate Expected term (years) Weighted average number of common shares outstanding Loss per common share Loss for the period Changes in fair value of embedded derivative and interest expense on convertible loans Changes in fair value of embedded derivative and interest expense on convertible loans Loss for the period Loss for the period Number of dilutive shares related to convertible loans Number of dilutive shares related to convertible loans Weighted average number of common shares outstanding Loss per common share Embedded derivatives convertible loans Call option derivative current Call/Put option derivatives Liability Class [Axis] Fair Value by Liability Class [Domain] Warrants [Member] Price Protection Derivative [Member] Price Protection Derivative and Warrants Embedded Derivative [Member] Convertible Bonds [Member] Put Option Derivative [Member] Warrants, beginning balance Embedded derivatives, beginning balance Convertible bonds, beginning balance Price protection derivative, beginning balance Put option derivative, beginning balance Repayment Repayment Additions Additions Conversion Conversion Changes in fair value related to Price Protection Derivative expired Changes in fair value related to Price Protection Derivative expired Changes in fair value related to warrants expired Changes in fair value related to warrants expired Changes in fair value during the period Changes in fair value during the period Option disposal Option disposal Changes in fair value due to extinguishment of convertible loan Changes in fair value due to extinguishment of convertible loan Translation adjustments Translation adjustments Warrants, ending balance Embedded derivatives, ending balance Convertible bonds, ending balance Price protection derivative, ending balance Put option derivative, ending balance Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets, Major Class Name [Domain] Backlog [Member] Customer Relationships [Member] Brand name [Member] Brand Know-How [Member] Know-How Gross Carrying Amount Accumulated amortization Net carrying amount of other intangible assets Amortization expenses, Next Twelve Months Amortization expenses, to Year Five Net operating loss carry forwards Research and development expenses Employee benefits Property and equipment Convertible bonds Convertible bonds Deferred income Intangible assets Less: Valuation allowance Net deferred tax liabilities Balance at the beginning of year Additions during the year Balance at end of year Decrease in fair value of warrants and financial liabilities measured at fair value Decrease in fair value of warrants and financial liabilities measured at fair value Stock-based compensation related to warrants granted due to issuance of credit facility Stock-based compensation related to warrants granted due to issuance of credit facility Interest expense on convertible loans Interest expense on convertible loans Foreign exchange loss, net Other Income Total financial expenses Total financial expenses Management and consulting fees to the Chairman of the Board Management and consulting fees to the Chairman of the Board Compensation to the nonexecutive directors (except the Chairman of the Board) Convertible loan from a related Fund Call option derivative (DerivativeAssetsCurrent) Total current assets Bank deposits Total non current assets TOTAL ASSETS Advance Payment On Account Of Grant Other Convertible Bonds Investments In Associate Net TOTAL CURRENT LIABILITIES Convertible loans Retirement benefits obligation Deferred taxes Other (OtherLiabilitiesNoncurrent) TOTAL LONG-TERM LIABILITIES TOTAL LIABILITIES Redeemable Non Controlling Interest Receipts on account of shares to be allotted Equity attributable to Orgenesis Inc. Non-controlling interests TOTAL EQUITY TOTAL LIABILITIES AND EQUITY REVENUES COST OF REVENUES GROSS PROFIT OTHER INCOME, net OPERATING LOSS FINANCIAL EXPENSES (INCOME), net SHARE IN LOSSES OF ASSOCIATED COMPANY LOSS BEFORE INCOME TAXES TAX EXPENSES NET LOSS NET INCOME ATTRIBUTABLE TO REDEEMABLE NON-CONTROLLING INTERESTS (INCLUDING REDEEMABLE) NET LOSS ATTRIBUTABLE TO THE COMPANY Basic Diluted Basic (WeightedAverageNumberOfSharesOutstandingBasic) Diluted (WeightedAverageNumberOfDilutedSharesOutstanding) Other Comprehensive (income) loss Translation adjustment Comprehensive loss COMPREHENSIVE LOSS ATTRIBUTED TO ORGENESIS INC. Stock Based Compensation Expenses Related To Options Granted To Employees And Directors Stockbased Compensation Related To Options Granted To Service Providers Including Receipts On Account Stockbased Compensation Related To Options Granted To Service Providers Including Receipts On Account Shares Issuance of shares and warrant due to conversion of convertible loans Issuance of shares and warrant due to conversion of convertible loans (Shares) Issuance Of Shares Along With Convertible Loan Issuance Of Shares Along With Convertible Loan Shares Reclassification Of Redeemable Common Stock Reclassification Of Redeemable Common Stock Shares Receipts On Account Of Shares Issuance Of Warrants And Beneficial Conversion Feature Of Convertible Loans Issuance Of Shares And Receipts On Account Of Shares To Be Allotted Related To Acquisition Of Atvio And Curecell Issuance Of Shares And Receipts On Account Of Shares To Be Allotted Related To Acquisition Of Atvio And Curecell Shares Issuance Of Shares And Receipts On Account Of Shares And Warrants To Be Allotted And Cancelation Of Contingent Shares Issuance Of Shares And Receipts On Account Of Shares And Warrants To Be Allotted And Cancelation Of Contingent Shares Shares Net income attributed to non-controlling interests Stock-based compensation Share in losses of associated company (GainLossOnInvestments) Loss from extinguishment of a convertible loan Depreciation and amortization expenses Net Gain On Remeasurement Of Previously Equity Interest In Atvio And Curecell To Acquisition Date Fair Value Change in fair value of warrants and embedded derivatives Change In Fair Value Of Convertible Bonds Increase in accounts receivable Decrease in related parties, net Increase in inventory Increase (decrease) in other assets Increase in prepaid expenses and other accounts receivable Increase (decrease) in employee and related payables Increase Decrease Increase Decrease In Advance Payment On Account Of Grant Net cash used in operating activities Purchase of property and equipment Acquisition of CureCell , net of cash acquired Acquisition Of Atvio Net Of Cash Acquired Investments in long term deposit Investments in associate Net cash used in investing activities Short-term line of credit Proceeds from issuance of shares and warrants (net of transaction costs) Loans received Proceeds From Repayments Of Redeemable Non Controlling Interest Repayment of convertible loans and convertible bonds Repayment of short and long-term debt Proceeds From Receipts On Account Of Shares To Be Allotted Repayment of short and long-term debt (RepaymentsOfLongTermDebt) Net cash provided by financing activities NET CHANGE IN CASH AND CASH EQUIVALENTS CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD Conversion Of Loans To Shares Of Common Stock And Warrants Supplemental Information On Interest Paid In Cash Classification Of Loan Receivable Into Services To Be Received From Curecell Convertible Loan [Text Block] Financial Expenses Net [Text 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H Rkf Twof General And Basis Of Presentation Zero Four Zero Four Four Zero N Rmw Zf F Dn M Md General And Basis Of Presentation Zero Four Zero Four Four Zero X Four G Bnc Three Z Six Rv V General And Basis Of Presentation Zero Four Zero Four Four Zero St B Five Sfv J H Ck Q General And Basis Of Presentation Zero Four Zero Four Four Zerosvn Z Wmq G Wg Four Four General And Basis Of Presentation Zero Four Zero Four Four Zeromsnp Six M V Z N Ks Nine General And Basis Of Presentation Zero Four Zero Four Four Zero M C Nine Zerox Fy K Two Cp C General And Basis Of Presentation Zero Four Zero Four Four Zerorvt Lmy Fivep L Qh Five General And Basis Of Presentation Zero Four Zero Four Four Zero Fn G Rd Xw T Xs S D General And Basis Of Presentation Zero Four Zero Four Four Zero Threet P L Rd Mxdr N K General And Basis Of Presentation Zero Four Zero Four Four Zerok Seven R Threeg G Eightm Sevenl C P General And Basis Of Presentation Zero Four Zero Four Four Zero X Oney Ninetky Eight H Jfh General And Basis Of Presentation Zero Four Zero Four Four Zerok R Pps Tk Fourx One Pb General And Basis Of Presentation Zero Four Zero Four Four Zero Zmp Q One Onek F Tg Five K General And Basis Of Presentation Zero Four Zero Four Four Zero X J Gs One W Twosq Bgf General And Basis Of Presentation Zero Four Zero Four Four Zeroq Nine Two S One Rvr Tn S Four General And Basis Of Presentation Zero Four Zero Four Four Zero Six Threex Pd Mw Vs J T F General And Basis Of Presentation Zero Four Zero Four Four Zeron Jf L J Sixd R R Ddm General And Basis Of Presentation Zero Four Zero Four Four Zeros K Fourkcs Kx Zero T T W General And Basis Of Presentation Zero Four Zero Four Four Zero Zghylrq Ninefbg X General And Basis Of Presentation Zero Four Zero Four Four Zerosp Threexq One Cv Hk H Three Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zero J J Gdk W Rqktkz Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zerogx Qr J M Q Two Dr G Zero Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zerozl Qgtb Three G G P B T Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zerof Q Nineg R T D Five F Zeromw Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zerozz M Wx Lz Wf F N Five Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zerodf W Fzy Jm M Eighttp Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zeros Nine Z Eightn One Zk Sxr K Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zero One K Eight Nine Vh X Nineyn Three F Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zeroxzh Zq Seven T Zerov R Fivep Exercise Of Call Options Of Curecell And Atvio Zero Four Zero Four Four Zero Z Nd Five Cs Zero Zp Twoyy Convertible Loans Outstanding From November Two Zero One Four And December Two Zero One Six [Member] Convertible Loans Outstanding From November Two Zero One Four [Member] Convertible Loans Outstanding From December Two Zero One Six [Member] Debt Instrument, Interest Rate, Stated Percentage Debt Instrument, Convertible, Conversion Price Class Of Warrant Or Right Grants In Period Class Of Warrant Or Right Grants In Period Exercise Price Debt Instrument, Convertible, Beneficial Conversion Feature Convertible Debt Transaction Cost Adjustment of Warrants Granted for Services Debt Conversion, Converted Instrument, Amount Debt Conversion Converted Instrument And Accrued Interest Amount Debt Conversion, Converted Instrument, Shares Issued Debt Conversion, Converted Instrument, Warrants or Options Issued Commitment Expenses Grants Receivable, Noncurrent Units Issued During Period Common Stock Shares Subscriptions Units Issued During Period Exercise Price Proceeds from Issuance of Private Placement Stock Issued During Period Shares Issued For Cash Consideration Stock Issued During Period Value Of Shares To Be Allotted Stock Issuance Fee Percentage Payments of Transaction Costs Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures Cash Received From Subscription Class Of Warrant Or Right Grants In Period Value Stock Based Compensation Zero Four Zero Four Four Four Five Six Four By One L Rw G Eight Mc Threel Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Lb K T Q L Onex Zerov Four X Stock Based Compensation Zero Four Zero Four Four Four Five Six Four X Twor Two T Xcf Dp Four Eight Stock Based Compensation Zero Four Zero Four Four Four Five Six Fourd One Ninesb Threeycl Zero V S Stock Based Compensation Zero Four Zero Four Four Four Five Six Four T One Lh W C Pzsg Lh Stock Based Compensation Zero Four Zero Four Four Four Five Six Four J Two F One B H Ts P Threem Z Stock Based Compensation Zero Four Zero Four Four Four Five Six Four J R Z P C W Sf G L S G Stock Based Compensation Zero Four Zero Four Four Four Five Six Fourv Oneg Ngy Fivegtm Z S Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Fbhsb Five Hwk Llg Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Nine Tkx P X Two M Jg P Seven Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Eightd Eight Mxl Sf Hm V J Stock Based Compensation Zero Four Zero Four Four Four Five Six Fourxw C Bn Oneq Xg N F Eight Stock Based Compensation Zero Four Zero Four Four Four Five Six Four L R Four D Qx R Vz Zerom T Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Jcw Q Nine Wp W Cpg Four Stock Based Compensation Zero Four Zero Four Four Four Five Six Fourd Mw Six G Nine X X Rp P Two Stock Based Compensation Zero Four Zero Four Four Four Five Six Fourqh Three Six Nine Eight Jhv J Onev Stock Based Compensation Zero Four Zero Four Four Four Five Six Four W Zeromg Np X Zxyr R Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Oneq Txd Bn Z K Dl P Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Sixx Hq Seven V Q Hq Five M S Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Oned Lk Sixbxh J Fivezd Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Onesx P Onez Tz Q N B One Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Four Two Four One M Zs Seven T Eight Three V Stock Based Compensation Zero Four Zero Four Four Four Five Six Fourtlb Seven T Gdh T Six Q Six Stock Based Compensation Zero Four Zero Four Four Four Five Six Fourln R Fivey Bn Q B Sixn Eight Stock Based Compensation Zero Four Zero Four Four Four Five Six Four M K M Hy Vs V Zero Eightrc Stock Based Compensation Zero Four Zero Four Four Four Five Six Fournz W Eight Vm C Qhk Tn Stock Based Compensation Zero Four Zero Four Four Four Five Six Four F Rk Pv Three T K One Jd C Stock Based Compensation Zero Four Zero Four Four Four Five Six Four G Fh Six G Fiveb B T Wrl Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Jby Mk Pr Five Five Eightf V Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Sixq Cd Four Kg T Eightfw Four Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Five Vz Six T Three Four Threegb One Zero Stock Based Compensation Zero Four Zero Four Four Four Five Six Four Rcs Cp Two Zeroch Lq Four Stock Based Compensation Zero Four Zero Four Four Four Five Six Foury Twol T H Ftk Cx Tw Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Transaction expenses related to GPP agreement Subsequent Events Zero Four Zero Four Four Four Five Six Four V R Seven One Eights Six Nineg G J S Subsequent Events Zero Four Zero Four Four Four Five Six Fourhg Threepzblry Cx J Subsequent Events Zero Four Zero Four Four Four Five Six Four C G Two W Fourp H F Eight R Z P Subsequent Events Zero Four Zero Four Four Four Five Six Fourss Ks W T Fy Seven M V B Subsequent Events Zero Four Zero Four Four Four Five Six Fourr L Zero Seven H C F Hr Five Zero Four The Contract Development And Manufacturing Organization [Member] The Cellular Therapy Business [Member] Operating expenses Other Income (Expense) Segment Performance Sharebased Compensation Acquisition Related Expenses Financial income (expenses), net Cash and cash equivalents (BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents) Property and equipment, net (BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedPropertyPlantAndEquipment) Inventory (BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedInventory) Other assets (BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsOther) Other Intangible assets Total assets (BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets) Deferred income from the company and others Deferred taxes (BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities) Fair value of convertible loan from the company Non-controlling interests (BusinessCombinationAcquisitionOfLessThan100PercentNoncontrollingInterestFairValue) Other liabilities Total liabilities (BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities) Total consideration transferred Fair value according of shares issued Acquisition date fair value of previously held equity interest Warrants Component Price Protection Derivative Component Shares Component Fair Value Of The Instruments Issued As Of The Conversion Dates Value of one common share Dividend yield Expected stock price volatility Risk free interest rate Expected term (years) Private Placement Warrants Component Private Placement Price Protection Derivative Component Private Placement Shares Component Private Placement Fair Value Of The Instruments Issued Value Of One Common Share (ValueOfOneCommonShare) Class of Warrant or Right, Valuation Method, Expected Dividend Rate Class of Warrant or Right, Valuation Method, Expected Volatility Rate Class of Warrant or Right, Valuation Method, Risk Free Interest Rate Class of Warrant or Right, Valuation Method, Expected Term Employee One [Member] Employee Two [Member] Employee Three [Member] Masthercells Employees One [Member] Masthercells Employees Two [Member] Employee Four [Member] Exercise price Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Vesting Period Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Grant Date Fair Value Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Expiration Period Nonemployee Ranges [Axis] Nonemployee One [Member] Nonemployee Two [Member] Nonemployee Three [Member] Value of one common share (SharePrice) Dividend yield (ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate) Expected stock price volatility (ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate) Risk free interest rate (ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate) Expected term (years) (SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1) Loss for the period Changes In Fair Value Of Embedded Derivative And Interest Expenses On Convertible Bonds Net Income Loss For The Period Number Of Dilutive Shares Related To Convertible Bonds Embedded derivatives convertible loans Price Protection Derivative And Warrants [Member] Warrants, beginning balance Put option derivative, beginning balance Repayment Additions To Financial Liabilities Conversion Of Financial Liabilities Changes In Fair Value Related To Price Protection Derivative Expired Changes In Fair Value Related To Warrants Expired Changes In Fair Value During The Period Option Disposal Changes In Fair Value Due To Extinguishment Of Convertible Loan Translation Adjustments To Financial Liabilities Brand [Member] Knowhow [Member] Gross Carrying Amount Accumulated amortization Net carrying amount of other intangible assets Amortization expenses, Next Twelve Months Amortization expenses, to Year Five Research and development expenses Employee benefits Property and equipment Deferred Tax Assets Convertible Bonds Deferred income (DeferredTaxAssetsDeferredIncome) Intangible assets Less: Valuation allowance Additions during the year Decrease In Fair Value Of Warrants And Financial Liabilities Measured At Fair Value Stock Based Compensation Related To Warrants Granted Due To Issuance Of Credit Facility Interest Expense On Convertible Loans Foreign exchange loss, net Other Income Total Financial Expenses Management And Consulting Fees To The Chairman Of The Board Compensation to the 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Document and Entity Information - shares
9 Months Ended
Aug. 31, 2018
Oct. 12, 2018
Document Type 10-Q  
Amendment Flag false  
Document Period End Date Aug. 31, 2018  
Trading Symbol orgs  
Entity Registrant Name Orgenesis Inc.  
Entity Central Index Key 0001460602  
Current Fiscal Year End Date --11-30  
Entity Filer Category Smaller Reporting Company  
Entity Common Stock, Shares Outstanding   15,570,973
Entity Current Reporting Status Yes  
Entity Voluntary Filers No  
Entity Well Known Seasoned Issuer No  
Document Fiscal Year Focus 2018  
Document Fiscal Period Focus Q3  

XML 18 R2.htm IDEA: XBRL DOCUMENT v3.10.0.1
CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($)
$ in Thousands
Aug. 31, 2018
Nov. 30, 2017
CURRENT ASSETS:    
Cash and cash equivalents $ 16,741 $ 3,519
Restricted Cash 396 0
Accounts receivable, net 4,154 1,336
Prepaid expenses and other receivables 1,437 841
Receivables from related party 0 691
Grants receivable 267 183
Inventory 1,659 725
Total current assets 24,654 7,295
NON-CURRENT ASSETS:    
Bank deposits 91 0
Call option derivative 0 339
Investments in associates, net 0 1,321
Property and equipment, net 11,056 5,104
Intangible assets, net 17,576 15,051
Goodwill 15,632 10,684
Other assets 287 78
Total non-current assets 44,642 32,577
TOTAL ASSETS 69,296 39,872
CURRENT LIABILITIES:    
Accounts payable 2,962 3,914
Accrued expenses and other payables 811 1,435
Employees and related payables 2,312 2,961
Related parties 177 116
Advance payments on account of grant 2,619 1,719
Short-term loans and current maturities of long-term loans 661 378
Deferred income 4,863 3,611
Current maturities of convertible loans 358 2,780
Other 190 0
TOTAL CURRENT LIABILITIES 14,953 16,914
LONG-TERM LIABILITIES:    
Loans payable 1,800 2,118
Convertible loans 0 2,415
Retirement benefits obligation 430 6
Deferred taxes 2,979 690
Other 524 0
TOTAL LONG-TERM LIABILITIES 5,733 5,229
TOTAL LIABILITIES 20,686 22,143
COMMITMENTS 0 0
REDEEMABLE NON-CONTROLLING INTEREST 18,646 3,606
EQUITY:    
Common stock of $0.0001 par value, 145,833,334 shares authorized, 13,620,262 and 9,872,659 shares issued and outstanding as of August 31, 2018 and November 30, 2017, respectively 1 1
Additional paid-in capital 80,889 55,334
Receipts on account of shares to be allotted 5,490 1,483
Accumulated other comprehensive income 660 1,425
Accumulated deficit (57,415) (44,120)
Equity attributable to Orgenesis Inc. 29,625 14,123
Non-controlling interests 339 0
TOTAL EQUITY 29,964 14,123
TOTAL LIABILITIES AND EQUITY $ 69,296 $ 39,872
XML 19 R3.htm IDEA: XBRL DOCUMENT v3.10.0.1
CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) - $ / shares
Aug. 31, 2018
Nov. 30, 2017
Common Stock, par or stated value $ 0.0001 $ 0.0001
Common Stock, shares authorized 145,833,334 145,833,334
Common Stock, shares issued 13,620,262 9,872,659
Common Stock, shares outstanding 13,620,262 9,872,659
XML 20 R4.htm IDEA: XBRL DOCUMENT v3.10.0.1
CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Aug. 31, 2018
Aug. 31, 2017
Aug. 31, 2018
Aug. 31, 2017
REVENUES $ 6,230 $ 2,562 $ 12,853 $ 6,712
COST OF REVENUES 3,381 1,867 7,220 4,900
GROSS PROFIT 2,849 695 5,633 1,812
RESEARCH AND DEVELOPMENT EXPENSES, net 1,902 500 3,456 1,906
AMORTIZATION OF INTANGIBLE ASSETS 505 423 1,386 1,201
SELLING, GENERAL AND ADMINISTRATIVE EXPENSES 4,008 3,184 10,675 7,887
OTHER INCOME, net (2,921) 0 (3,237) 0
OPERATING LOSS 645 3,412 6,647 9,182
FINANCIAL EXPENSES (INCOME), net 1,070 (45) 3,164 2,534
SHARE IN LOSSES OF ASSOCIATED COMPANY 202 152 732 348
LOSS BEFORE INCOME TAXES 1,917 3,519 10,543 12,064
TAX EXPENSES 2,353 421 1,680 493
NET LOSS 4,270 3,940 12,223 12,557
NET INCOME ATTRIBUTABLE TO NON-CONTROLLING INTERESTS (INCLUDING REDEEMABLE) 800 0 1,072 0
NET LOSS ATTRIBUTABLE TO THE COMPANY $ 5,070 $ 3,940 $ 13,295 $ 12,557
LOSS PER SHARE:        
Basic $ (0.35) $ (0.38) $ (1.04) $ (1.32)
Diluted $ (0.35) $ (0.40) $ (1.04) $ (1.34)
WEIGHTED AVERAGE NUMBER OF SHARES USED IN COMPUTATION OF BASIC AND DILUTED LOSS PER SHARE:        
Basic 14,355,430 10,279,180 12,774,802 9,477,211
Diluted 14,355,430 10,385,499 12,774,802 9,503,253
OTHER COMPREHENSIVE LOSS:        
Net Loss $ 4,270 $ 3,940 $ 12,223 $ 12,557
Other Comprehensive (income) loss - Translation adjustment 416 (1,430) 765 (2,419)
Comprehensive loss 4,686 2,510 12,988 10,138
Net income attributed to non-controlling interests (including redeemable) 800 0 1,072 0
COMPREHENSIVE LOSS ATTRIBUTED TO ORGENESIS INC. $ 5,486 $ 2,510 $ 14,060 $ 10,138
XML 21 R5.htm IDEA: XBRL DOCUMENT v3.10.0.1
CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY - USD ($)
$ in Thousands
Common Stock [Member]
Additional Paid-in Capital [Member]
Receipts on Account of Share to be Allotted [Member]
Accumulated Other Comprehensive Loss [Member]
Accumulated Deficit [Member]
Equity Attributable to Orgenesis Inc. [Member]
Non-Controlling Interest [Member]
Total
Beginning Balance at Nov. 30, 2016 $ 1 $ 45,454   $ (1,205) $ (31,753) $ 12,497   $ 12,497
Beginning Balance (Shares) at Nov. 30, 2016 9,508,068              
Stock-based compensation to employees and directors   1,156       1,156   1,156
Stock-based compensation to service providers   1,824       1,824   1,824
Stock-based compensation to service providers (Shares) 79,167              
Issuance of warrants and beneficial conversion feature of convertible loans   2,550       2,550   2,550
Issuance of shares and receipts on account of shares and warrants to be allotted   3,383 $ 852     4,235   4,235
Issuance of shares and receipts on account of shares and warrants to be allotted (Shares) 244,743              
Comprehensive income (loss) for the period       2,419 (12,557) (10,138)   (10,138)
Ending Balance at Aug. 31, 2017 $ 1 54,367 852 1,214 (44,310) 12,124   12,124
Ending Balance (Shares) at Aug. 31, 2017 9,831,978              
Beginning Balance at Nov. 30, 2017 $ 1 55,334 1,483 1,425 (44,120) 14,123   14,123
Beginning Balance (Shares) at Nov. 30, 2017 9,872,659              
Stock-based compensation to employees and directors   1,416       1,416   1,416
Stock-based compensation to service providers   1,568       1,568   1,568
Stock-based compensation to service providers (Shares) 195,000              
Issuance of shares from investments and conversion of convertible loans (Shares) 1,341,134              
Issuance of warrants and beneficial conversion feature of convertible loans   7,330       7,330   7,330
Issuance of shares and receipts on account of shares to be allotted related to acquisition of Atvio and CureCell   600 1,853     2,453 $ 300 2,753
Issuance of shares and receipts on account of shares to be allotted related to acquisition of Atvio and CureCell (Shares) 83,965              
Issuance of shares and receipts on account of shares and warrants to be allotted   13,466 2,154     15,620   15,620
Issuance of shares and receipts on account of shares and warrants to be allotted (Shares) 1,990,858              
Beneficial conversion feature of convertible loans and Warrants issued   323       323   323
Issuance of Shares due to exercise of warrants   852       852   852
Issuance of Shares due to exercise of warrants (Shares) 136,646              
Comprehensive income (loss) for the period       (765) (13,295) (14,060) 39 (14,021)
Ending Balance at Aug. 31, 2018 $ 1 $ 80,889 $ 5,490 $ 660 $ (57,415) $ 29,625 $ 339 $ 29,964
Ending Balance (Shares) at Aug. 31, 2018 13,620,262              
XML 22 R6.htm IDEA: XBRL DOCUMENT v3.10.0.1
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
9 Months Ended
Aug. 31, 2018
Aug. 31, 2017
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (12,223) $ (12,557)
Adjustments required to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 2,984 2,817
Share in losses of associated company 732 348
Depreciation and amortization expenses 1,833 1,874
Net gain on remeasurement of previously equity interest in Atvio and CureCell to acquisition date fair value (4,509) 0
Change in fair value of warrants and embedded derivatives 11 (230)
Change in fair value of convertible bonds 0 (157)
Interest expenses accrued on loans and convertible loans (including amortization of beneficial conversion feature) 2,856 818
Changes in operating assets and liabilities, net of business combination:    
Increase in accounts receivable (2,818) (682)
Decrease in related parties, net (379) 0
Increase in inventory (848) (484)
Increase (decrease) in other assets 65 (1)
Increase in prepaid expenses and other accounts receivable (148) (818)
Decrease in accounts payable (1,723) (1,230)
Increase (decrease) in accrued expenses and other payables (686) 192
Increase (decrease) in employee and related payables (820) 554
Increase in deferred income 705 3,268
Increase in advance payments and receivables on account of grant, net 815 2,358
Increase in deferred taxes 1,680 494
Net cash used in operating activities (12,473) (3,436)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchase of property and equipment (4,430) (639)
Disposals of property and equipment 0 31
Acquisition of CureCell , net of cash acquired (See ) 58 0
Acquisition of Atvio , net of cash acquired (See ) 245 0
Investments in long term deposit (92) 0
Investments in associate 0 (835)
Net cash used in investing activities (4,219) (1,443)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Short-term line of credit 0 (21)
Proceeds from issuance of shares and warrants (net of transaction costs) 12,666 4,307
Proceeds from issuance of convertible loans (net of transaction costs) 720 4,932
Repayment of convertible loans and convertible bonds (177) (3,766)
Proceeds from receipts on account of shares to be allotted 3,626 0
Increase in redeemable non-controlling interests 14,007 0
Repayment of short and long-term debt (331) (1,102)
Net cash provided by financing activities 30,511 4,350
NET CHANGE IN CASH AND CASH EQUIVALENTS 13,819 (529)
EFFECT OF EXCHANGE RATE CHANGES ON CASH AND CASH EQUIVALENTS (201) 400
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD 3,519 891
CASH AND CASH EQUIVALENTS AT END OF PERIOD 17,137 762
SUPPLEMENTAL NON-CASH FINANCING ACTIVITIES    
Conversion of loans and bonds (including accrued interest) to common stock and warrants 7,511 106
Classification of loan receivable into services to be received from CureCell $ 813 $ 0
XML 23 R7.htm IDEA: XBRL DOCUMENT v3.10.0.1
GENERAL AND BASIS OF PRESENTATION
9 Months Ended
Aug. 31, 2018
GENERAL AND BASIS OF PRESENTATION [Text Block]

NOTE 1 - GENERAL AND BASIS OF PRESENTATION

a.

General

Orgenesis Inc., a Nevada corporation (“Orgenesis” or the “Company”), is a service and research company in the field of the regenerative medicine industry with a focus on cell therapy development and manufacturing for advanced medicinal products. In addition, the Company is focused on developing novel and proprietary cell therapy trans-differentiation technologies for the treatment of diabetes. The consolidated financial statements include the accounts of Orgenesis Inc. and its subsidiaries, including those of the Masthercell Global group, a contract development and manufacturing organization, or CDMO, specializing in cell therapy development and manufacturing for advanced medicinal products in the USA, Belgium, Korea and Israel (See Note 4 for explanation that during the third fiscal quarter that the Company gained control of Atvio and CureCell); Orgenesis SPRL (the “Belgian Subsidiary”), a Belgian-based subsidiary which is engaged in development and manufacturing activities together with clinical development studies in Europe; Orgenesis Maryland Inc. (the “U.S. Subsidiary”), a Maryland corporation; and Orgenesis Ltd., an Israeli corporation, (the “Israeli Subsidiary”).

The Company’s goal is to industrialize cell therapy for fast, safe and cost-effective production in order to provide rapid therapies for any market around the world through a world-wide network of CDMO joint venture partners. The Company’s trans-differentiation technologies for treating diabetes, which will be referred to as the cellular therapy (“CT”) business, is based on a technology licensed by Tel Hashomer Medical Research (“THM”) to the Israeli Subsidiary that demonstrates the capacity to induce a shift in the developmental fate of cells from the liver and trans-differentiating (converting) them into “pancreatic beta cell-like” insulin-producing cells.

As used in this report and unless otherwise indicated, the term “Company” refers to Orgenesis Inc. and its subsidiaries (“Subsidiaries”). Unless otherwise specified, all amounts are expressed in United States Dollars.

On November 16, 2017, the Company implemented a reverse stock split of its outstanding shares of common stock at a ratio of 1 -for- 12 shares. The reverse stock split has been reflected in these condensed consolidated financial statements.

On March 13, 2018, the Company's common stock began to be listed and traded on the Nasdaq Capital Market under the symbol “ORGS.”

Consolidation of CDMO Entities and Strategic Funding

On June 28, 2018, the Company, Masthercell Global Inc. (a newly formed Delaware subsidiary of Orgenesis Inc being the Company that holds the Company’s CDMO business (“Masthercell Global”)), Great Point Partners, LLC, a manager of private equity funds focused on growing small to medium sized heath care companies (“Great Point”), and certain of Great Point’s affiliates, entered into a series of definitive strategic agreements intended to finance, strengthen and expand Orgenesis’ CDMO business. In connection therewith, the Company, Masthercell Global and GPP-II Masthercell, LLC, a Delaware limited liability company (“GPP-II”) and an affiliate of Great Point entered into Stock Purchase agreement (the “SPA”) pursuant to which GPP-II purchased 378,000 shares of newly designated Series A Preferred Stock of Masthercell Global (the “Masthercell Global Preferred Stock”), representing 37.8% of the issued and outstanding share capital of Masthercell Global, for cash consideration to be paid into Masthercell Global of up to $25 million, of which $13.2 million is subject to certain contingencies described below (the “Consideration”). Orgenesis holds 622,000 shares of Masthercell Global’s Common Stock, representing 62.2% of the issued and outstanding equity share capital of Masthercell Global. An initial cash payment of $11.8 million of the Consideration was remitted at closing by GPP-II to Masthercell Global. $1.5 Million of the initial capital contributed to Masthercell Global was used to reimburse the Investors for their fees and expenses incurred in conjunction with this transaction. The $1.5 million will reflect the entire fee payable under this transaction (net payment of $10.3 million). The follow up payment will be in the amount of $6,600,000 to be made in each of years 2018 and 2019 (the “Future Payments”), or an aggregate of $13.2 million, if (a) Masthercell Global achieves specified EBITDA and revenues targets during each of these years, and (b) the Orgenesis’ shareholders approve on or before December 31, 2019 certain provisions of the Stockholders’ Agreement entered into by these parties. None of the future Consideration amounts, if any, will result in an increase in GPP-II’s equity holdings in Masthercell Global beyond the 378,000 shares of Series A Preferred Stock issued to GPP-II at closing. Notwithstanding the foregoing, GPP-II may, in its sole discretion, elect to pay all or a portion of the future Consideration amounts even if the financial targets described above have not been achieved and the Orgenesis Stockholder Approval has not been obtained.

In connection with the entry into the SPA described above, each of the Company, Masthercell Global and GPP-II entered into the Masthercell Global Inc. Stockholders’ Agreement (the “Stockholders’ Agreement”) providing for certain restrictions on the disposition of Masthercell Global securities, the provisions of certain options and rights with respect to the management and operations of Masthercell Global, certain rights to GPP-II (including, without limitation, a tag along right, drag along right and certain protective provisions). After the earlier of the second anniversary of the closing or certain enumerated circumstances, GPP-II is entitled to effectuate a spinoff of Masthercell Global and the Masthercell Global Subsidiaries (the “Spinoff”).  The Spinoff is required to reflect a market value determined by one of the top ten independent accounting firms in the U.S. selected by GPP, provided that under certain conditions, such market valuation shall reflect a valuation of Masthercell Global and the Masthercell Global Subsidiaries of at least $50 million. In addition, upon certain enumerated events described below, GPP-II is entitled, at its option, to put to the Company (or, at Company’s discretion, to Masthercell Global if Masthercell Global shall then have the funds available to consummate the transaction) its shares in Masthercell Global or, alternatively, purchase from the Company its share capital in Masthercell Global at a purchase price equal to the fair market value of such equity holdings provided that the purchase price shall not be greater than three times the price per share of Masthercell Global Preferred Stock paid by GPP-II and shall not be less than the price per share of Masthercell Global Preferred Stock paid by GPP-II. GPP-II may exercise its put or call option upon the occurrence of any of the following: (i) there is an Activist Shareholder of the Company; (ii) the Chief Executive Officer and/or Chairman of the board of directors of the Company resigns or is replaced, removed, or terminated for any reason prior to June 28, 2023; (iii) there is a Change of Control event of the Company; or (iv) the industry expert director appointed to the board of directors of Masthercell Global is removed or replaced (or a new such director is appointed) without the prior written consent of GPP-II. For the purposes of the foregoing, the following definitions shall apply: (A) “Activist Shareholder” shall mean any Person who acquires shares of capital stock of the Company who either: (x) acquires more than a majority of the voting power of the Company, (y) actively takes over and controls a majority of the board of directors of the Company, or (z) is required to file a Schedule 13D with respect to such Person’s ownership of the Company and has described a plan, proposal or intent to take action with respect to exerting significant pressure on the management of or directors of, the Company; and (B) “Change of Control” shall mean any of: (a) the acquisition, directly or indirectly (in a single transaction or a series of related transactions) by a Person or group of Persons of either (I) a majority of the common stock of the Company (whether by merger, consolidation, stock purchase, tender offer, reorganization, recapitalization or otherwise), or (II) all or substantially all of the assets of the Company and its Subsidiaries (but only if such transaction includes the transfer of Securities held by the Company), (b) if any four (4) of the directors of the Company as of June 28, 2018 are removed or replaced or for any other reason cease to serve as directors of the Company, (c) the filing of a petition in bankruptcy or the commencement of any proceedings under bankruptcy laws by or against the Company, provided that such filing or commencement shall be deemed a Change of Control immediately if filed or commenced by the Company or after sixty (60) days if such filing is initiated by a creditor of the Company and is not dismissed; (d) insolvency of the Company that is not cured by the Company within thirty (30) days; (e) the appointment of a receiver for the Company, provided that such appointment shall constitute an Change of Control immediately if the appointment was consented to by the Company or after sixty (60) days if not consented to by the Company and such appointment is not terminated; or (f) or dissolution of the Company.

The Stockholders’ Agreement further provides that GPP-II is entitled, at any time, to convert its share capital in Masthercell Global for the Company’s common stock in an amount equal to the lesser of (a)(i) the fair market value of GPP-II’s shares of Masthercell Global Preferred Stock to be exchanged, divided by (ii) the average closing price per share of Orgenesis Common Stock during the thirty (30) day period ending on the date that GPP-II provides the exchange notice (the “Exchange Price”) and (b)(i) the fair market value of GPP-II’s shares of Masthercell Global Preferred Stock to be exchanged assuming a value of Masthercell Global equal to three and a half (3.5) times the revenue of Masthercell Global during the last twelve (12) complete calendar months immediately prior to the exchange divided by (ii) the Exchange Price; provided, that in no event will (A) the Exchange Price be less than a price per share that would result in Orgenesis having an enterprise value of less than $250,000,000 and (B) the maximum number of shares of Orgenesis Common Stock to be issued shall not exceed 2,704,247 shares of outstanding Orgenesis Common Stock (representing approximately 19.99% of then outstanding Orgenesis Common Stock), unless Orgenesis obtains shareholder approval for the issuance of such greater amount of shares of Orgenesis Common Stock in accordance with the rules and regulations of the Nasdaq Stock Market.

Great Point and Masthercell Global entered into an advisory services agreement pursuant to which Great Point is to provide management services to Masthercell Global for which Great Point will be compensated at an annual base compensation equal to the greater of (i) $250,000 per each 12 month period or (ii) 5% of the EBITDA for such 12 month period, payable in arrears in quarterly installments; provided, that these payments will (A) begin to accrue immediately, but shall not be paid in cash to Great Point until such time as Masthercell Global generates EBITDA of at least $2,000,000 for any 12 month period or the sale of or change in control of Masthercell Global, and (B) shall not exceed an aggregate annual amount of $500,000. Such compensation accrues but is not owed to Great Point until the earlier of (i) Masthercell Global generating EBITDA of at least $2 million for any 12 months period following the date of the agreement or (ii) a Sale of the Company or Change of Control of the Company (as both terms are defined therein).

GPP Securities, LLC, a Delaware limited liability company and an affiliate of Great Point and Masthercell Global entered into a transaction services agreement pursuant to which GPP Securities, LLC is to provide certain brokerage services to Masthercell Global for which GPP Securities LLC will be entitled to a certain Exit Fee and Transaction Fee (as both terms are defined in the agreement), such fees not to be less than 2 percent of the applicable transaction value.

The Company accounted for the investment made by GPP as a redeemable non-controlling interest due to the embedded redemption feature whose settlement is not at the Company discretion.

Corporate Reorganization

Contemporaneous with the execution of the SPA and the Stockholders’ Agreement, Orgenesis and Masthercell Global entered into a Contribution, Assignment and Assumption Agreement pursuant to which Orgenesis contributed to Masthercell Global assets relating to the CDMO Business (as defined below), including the CDMO subsidiaries (the “Corporate Reorganization”). For further details see Note 4. Together with MaSTherCell S.A., Atvio and CureCell are directly held subsidiaries under Masthercell Global (collectively, the “Masthercell Global Subsidiaries”).

Masthercell Global, through the Masthercell Global Subsidiaries, will be engaged in the business of providing manufacturing and development services to third parties related to cell therapy products, and the creation and development of technology, and optimizations in connection with such manufacturing and development services for third parties (the “CDMO Business”). Under the terms of the Stockholders’ Agreement, Orgenesis has agreed that so long as it owns equity in Masthercell Global and for two years thereafter it will not engage in the CDMO Business, except through Masthercell Global (but may continue to engage in its other areas of business). In addition, except for certain limited circumstances, each of Orgenesis and GPP-II agreed in the Stockholders’ Agreement to not recruit or solicit or hire any officer or employee of Masthercell Global that was or is involved in the CDMO Business.

b.

Liquidity

As of August 31, 2018, the Company accumulated losses of approximately $57.4 million. Although the Company is showing positive revenue and gross profit trends in its CDMO business, the Company expects to incur further losses in the CT business.

To date, the Company has been funding operations primarily from the proceeds from private placements of the Company’s convertible debt and equity securities and from revenues generated by MaSTherCell S.A. From December 1, 2017 through August 31, 2018, the Company received, through MaSTherCell S.A., proceeds of approximately $11.5 million in revenues and accounts receivable from customers, and $16.5 million from the private placement to accredited investors of the Company's equity and equity linked securities and convertible loans and exercise of warrants, out of which $8.1 million are from the institutional investor with whom the Company entered into definitive agreements in January 2017 for the private placement of units (see also Note 7(a)).  In addition, from September 1, 2018 through October 12, 2018, the Company raised $3.4 million from the private placement referred to above of unsubscribed units under such investor’s subscription agreement, and proceeds of approximately $2.9 million in accounts receivable from customers of MaSTherCell S.A. See also Note 12.

c.

Basis of Presentation

These unaudited condensed consolidated financial statements of the Company have been prepared in accordance with U.S. GAAP, pursuant to the rules and regulations of the United States Securities and Exchange Commission (“SEC”) for interim financial statements. Accordingly, they do not contain all information and notes required by U.S. GAAP for annual financial statements. In the opinion of management, the unaudited condensed consolidated interim financial statements reflect all adjustments, which include normal recurring adjustments, necessary for a fair statement of the Company’s consolidated financial position as of August 31, 2018, and the consolidated statements of comprehensive loss for the three and nine months ended August 31, 2018 and 2017, and the changes in equity and cash flows for the nine-month period ended August 31, 2018 and 2017. The interim results are not necessarily indicative of the results to be expected for the year ending November 30, 2018. These unaudited interim condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and notes thereto included in the Company’s Annual Report on Form 10-K for the year ended November 30, 2017.

d.

Collaboration and Joint Venture Agreements

Mircod Limited

On June 19, 2018, the Company and Mircod Limited, a company formed under the laws of Cyprus (“Mircod”) entered into a Collaboration and License Agreement (the “Collaboration Agreement”) for the research, development and commercialization of potential key technologies related to biological sensing for the Company's clinical development and manufacturing projects (the “Development Project”). Within 45 days of the execution of the Collaboration Agreement, the parties are to approve a written project development plan outlining each party’s responsibilities with respect to the Development Project, and the Company will be funding the projected development costs as outlined in the development plan. Under the terms of the Collaboration Agreement, the Company remitted to Mircod an upfront payment of $50,000.

Under the Collaboration Agreement, all results of such collaboration (“Project Results”) shall be jointly owned by Mircod and the Company. The Company was granted an exclusive, worldwide sub licensable license under Mircod’s right in such Project Results to use and commercialize Project Results in consideration for a royalty of 5% of Net Sales (as defined in the Collaboration Agreement) of products incorporating Project Results.

Subject to completion of the Development Project, Mircod and the Company are to negotiate and enter into a manufacturing and supply agreement under which Mircod is to manufacture and supply products incorporating the Project Results and, at the Company’s request, to provide support and maintenance service for such products. If for whatever reason the parties fail to enter into such manufacturing and supply agreement within 90 days of the completion of the Development Project or if Mircod is unable to perform such services, the Company is entitled to manufacture the products, in which event Mircod will be entitled to a payment of $80,000 and royalties on Net Sales are to increase to 8% of Net Sales.

HekaBio K.K

On July 10, 2018, the Company and HekaBio K.K. (“HB”), a corporation organized under the laws of Japan entered into a Joint Venture Agreement (the “JVA”) pursuant to which the parties will collaborate in the clinical development and commercialization of regeneration and cell and gene therapeutic products (hereinafter the “Products”) in Japan (the “Project”). The parties intend to pursue the joint venture through a newly established Japanese company (hereinafter the “JV Company”) which the Company by itself, or together with a designee, will hold a 49% participating interest therein, with the remaining 51% participating interest being held by HB. HB will fund, at its sole expense, all costs associated with obtaining the requisite regulatory approvals for conducting clinical trials, as well as performing all clinical and other testing required for market authorization of the Products in Japan.

Under the JVA, each party may invest up to $10 million, which may take the form of a loan, if required, as determined by the steering committee. The terms of such investment, if any, will be on terms mutually agreeable to the parties, provided that the minimum pre-money valuation for any such investment shall not be less than $10 million. Additionally, HB was granted an option to affect an equity investment in the Company of up to $15 million within the next 12 months on mutually agreeable terms. If such investment is in fact consummated, the Company agreed to invest in the JV Company by way of a convertible loan an amount to HB’s pro-rata participating interest in the JV Company, which initially will be at 51%. Such loan may then be converted by the Company into share capital of the JV company at an agreed upon formula for determining JV Company valuation which in no event shall be less than $10 million. Under the JVA, the Company can require HB to sell to the Company its participating (including equity) interest in the JV Company in consideration for the issuance of the Company’s common stock based on an agreed upon formula for determining JV Company valuation which in no event shall be less than $10 million.

In addition, under the JVA, the Company shall grant the JV Company an exclusive license to certain intellectual property of the Company as may be required for the JV Company to develop and commercialize the Products in Japan. In consideration of such license, the JV Company shall pay the Company, in addition to other payments, royalties at the rate of 10% of the JV Company’s net sales of Products.

It was further agreed that the JV Company shall grant the Company (and its affiliates) a non-exclusive, worldwide (other than Japan), royalty-free and fully paid-up license to use and practice, for any purpose, new inventions, discoveries and intellectual property rights that are generated by and/or on behalf of HB and/or the JV Company in connection with the Project.

All matters pertaining to such license rights shall be governed under a separate license agreement to be entered by and between the Company and the JV Company.

As of August 31, 2018, no activity had begun in the said JV and no investments were made therein.

Image Securities Ltd.

On July 11, 2018, the Company and Image Securities Ltd., a corporation with its registered office in Grand Cayman, Grand Cayman Islands (“India Partner”) entered into a Joint Venture Agreement (the “India JVA”) pursuant to which the parties will collaborate in the development and/or marketing, clinical development and commercialization of cell therapy products in India (the “Cell Therapy Products”). The India Partner will collaborate with a network of healthcare facilities and a healthcare infrastructure as well as financial partners to advance the development and commercialization of the cell therapy products.

The India JVA becomes effective upon the consummation of an equity investment by the India partner in the Company of $5 million within 15 days of the execution of the India JVA through the purchase of units of Orgenesis securities at a per unit purchase price payable into the Company of $6.24, with each unit comprised of one share of the Company and three-year warrant for the acquisition of an additional common share at a per share exercise price of $6.24. Subject to the consummation of such equity investment in the Company, the Company is to advance to the JV Company a convertible loan in the amount of $5 million. The loan is convertible into equity capital of the JV Company at an agreed upon formula for determining JV Company valuation. The investment in the Company by the India Partner would be the consummation of the previously disclosed private placement subscription agreement entered into in December 2016 between the Company and an affiliate of the India Partner pursuant to which the closing of such subscription agreement was by the terms thereof delayed until terms comprising the India JV were mutually agreed to.

Under the India JVA, the India Partner agreed to invest in the JV $10 million within 12 months of the incorporation of the JV Company. If for whatever reason such investment is not made by the India Partner within such time, then Orgenesis is authorized to convert its above-referenced loan into 50% of the equity capital of the JV Company on a fully diluted basis, provided that if the pre-money valuation of the JV Company is then independently determined to be less than $5 million, then such conversion to be effected in the basis of such valuation.

As of August 31, 2018, no activity had begun in the said JV and no investments were made therein.

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SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
9 Months Ended
Aug. 31, 2018
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES [Text Block]

NOTE 2 - SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

The accounting policies adopted are consistent with those of the previous financial year, except as noted below regarding the adoption of new accounting pronouncements.

Recently Issued Accounting Pronouncements- adopted by the Company

1)    In November 2016, the FASB issuedASU 2016-18, Statement of Cash Flows (Topic 230): Restricted Cash (a Consensus of the FASB Emerging Issues Task Force) (“ASU 2016-18”), which requires entities to include amounts generally described as restricted cash and restricted cash equivalents in cash and cash equivalents when reconciling beginning-of-period and end-of-period total amounts shown on the statement of cash flows. ASU 2016-18 is effective for annual reporting periods (including interim periods within those annual reporting periods) beginning after December 15, 2017. The Company adopted this standard as of beginning of 2018. The Company did not have restricted cash in the previously presented period. Therefore, there is no impact for the new adoption on previously reported periods.

2)    In July 2017, the Financial Accounting Standards Board (FASB) issued Accounting Standards Update (ASU) 2017-11, "Earnings Per Share (Topic 260); Distinguishing Liabilities from Equity (Topic 480; Derivatives and Hedging (Topic 815)", ("ASU 2017-11"). This update was issued to address complexities in accounting for certain equity-linked financial instruments containing down round features. The amendment changes the classification analysis of these financial instruments (or embedded features) so that equity classification is no longer precluded. The amendments in ASU 2017-11 are effective for annual reporting periods beginning after December 15, 2018, including interim reporting periods within those annual reporting periods. Early adoption is permitted. The Company elected to early adopt the standard effective September 1, 2017, retrospectively.  Following is the result of the adoption on the Company’s condensed consolidated financial statements previously reported:

Shareholders’ Equity

    August 31, 2017  
          Impact        
    As reported     of        
    Previously     adoption     As revised  
    In thousands  
                   
Additional paid-in capital $ 50,518   $ 3,849   $ 54,367  
Accumulated deficit $ (41,345 ) $ (2,965 ) $ (44,310 )
Total equity $ 11,251   $ 873   $ 12,124  

Statement of Comp[rehensive Loss

    Nine months ended August 31, 2017     Three months ended August 31, 2017  
    As                 As              
    reported     Impact of     As     reported     Impact of     As  
    Previously     adoption     revised     Previously     adoption     revised  
    In thousands  
                                     
                                     
Financial expenses (income), net $ 1,488   $ 1,046   $ 2,534   $ (2,032 ) $ 1,987   $ (45 )
Loss before income taxes $ 11,018   $ 1,046   $ 12,064   $ 1,532   $ 1,987   $ 3,519  
Net loss $ 11,511   $ 1,046   $ 12,557   $ 1,953   $ 1,987   $ 3,940  
XML 25 R9.htm IDEA: XBRL DOCUMENT v3.10.0.1
SEGMENT INFORMATION
9 Months Ended
Aug. 31, 2018
SEGMENT INFORMATION [Text Block]

NOTE 3 - SEGMENT INFORMATION

The Chief Executive Officer ("CEO") is the Company’s chief operating decision-maker ("CODM").

Based on the Company's organizational structure, its business activities and information reviewed by the CODM for the purposes of allocating resources and assessing performance, management has determined that there are two operating segments.

CDMO

The CDMO activity is comprised of a specialization in cell therapy development for advanced therapeutic products and is comprised of two types of services to its customers: (i) process and assay development services and (ii) cGMP contract manufacturing services. The CDMO activities include the operations of Masthercell Global since the Corporate Reorganization (which includes the operations of CureCell and Atvio from the same date) and MaSTherCell prior to the Corporate Reorganization. As of the date of acquisition of CureCell and Atvio their activity is included in this segment.

CT Business

The CT Business activity is based on our technology that demonstrates the capacity to induce a shift in the developmental fate of cells from the liver and differentiating (converting) them into “pancreatic beta cell-like” insulin producing cells for patients with Type 1 Diabetes. This segment is comprised of all entities aside from Masthercell Global, CureCell and Atvio.

The CODM does not review assets by segment, therefore the measure of assets has not been disclosed for each segment.

Segment data for the nine months ended August 31, 2018 is as follows:

                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Revenues from external customers $ 15,807   $ 83   $ (3,037 ) $ 12,853 *  
Cost of revenues   (7,826 )   -     927     (6,899 )
Segment gross profit (loss)   7,981     83     (2,110 )   5,954  
Research and development expenses, net   (245 )   (4,764 )   2,110     (2,899 )
Operating expenses   (3,895 )   (4,448 )         (8,343 )
Other income   228     -           228  
Segment operating profit (loss)   4,069     (9,129 )   -     (5,060 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
     Depreciation and amortization   (1,807 )   (7 )            
Segment performance   2,262     (9,136 )            

* The Company's revenues consist of: $9,493 from services and $3,360 from goods sold.

Reconciliation of segment performance to loss for the nine months ended August 31, 2018:

    Nine months  
    Ended August  
    31, 2018  
    in thousands  
Segment performance   (6,874 )
Stock-based compensation   (2,782 )
Financial expenses, net   (3,164 )
Net gain on remeasurement of previously
     equity interest in Atvio and CureCell to 
     acquisition date fair value
  4,509  
Transaction expenses related to GPP agreement   (1,500 )
Share in losses of associated companies   (732 )
Loss before income tax $ (10,543 )

Segment data for the three months ended August 31, 2018 is as follows:

                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Revenues from external customers $ 8,092   $ 83   $ (1,945 ) $ 6,230 *  
Cost of revenues   (3,908 )   -     539     (3,369 )
Segment gross profit (loss)   4,184     83     (1,406 )   2,861  
Research and development expenses, net   (245 )   (3,298 )   1,406     (1,737 )
Operating expenses   (1,712 )   (1,453 )         (3,165 )
Other expenses   (88 )   -           (88 )
Segment operating profit (loss)   2,139     (4,268 )   -     (2,129 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
     Depreciation and amortization   (567 )   (3 )            
Segment performance   1,572     (4,271 )            

* The Company's revenues consist of: $4,473 from services and $1,757 from goods sold.

Reconciliation of segment performance to loss for the three months ended August 31, 2018:

    Three Months  
    Ended August  
    31, 2018  
    in thousands  
  Segment performance   (2,699 )
Stock-based compensation   (955 )
Financial expenses, net   (1,070 )
Share in losses of associated companies   (202 )
Net gain on remeasurement of previously 
     equity interest in Atvio and CureCell to 
     acquisition date fair value
  4,509  
Transaction expenses related to GPP agreement   (1,500 )
Loss before income tax $ (1,917 )

Segment data for the nine months ended August 31, 2017 is as follows:

                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Revenues from external customers $ 7,705   $   -   $ (993 ) $ 6,712  
Cost of revenues   (4,358 )         403     (3,955 )
Segment gross profit (loss)   3,347           (590 )   2,757  
Research and development expenses, net         (1,932 )   590     (1,342 )
Operating expenses   (916 )   (6,060 )         (6,976 )
Segment operating profit (loss)   2,431     (7,992 )   -     (5,561 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
Depreciation and amortization expenses   (2,145 )   (7 )            
Segment Performance   286     (7,999 )            

Reconciliation of segment performance to loss for the nine months ended August 31, 2017:

    Nine Months  
    Ended  
    August 31,  
    2017  
    in thousands  
Segment performance   (7,713 )
Stock-based compensation   (1,469 )
Financial expenses, net   (2,534 )
Share in losses of associated companies   (348 )
Loss before income tax   (12,064 )

Segment data for the three months ended August 31, 2017 is as follows:

                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Net revenues from external customers $ 2,956           (394 )   2,562  
Cost of revenues   (1,439 )         95     (1,344 )
Segment gross profit (loss)   1,517           (299 )   1,218  
Research and development expenses, net         (688 )   299     (389 )
Operating expenses   (1,641 )   (1,272 )         (2,913 )
Segment operating profit (loss)   (124 )   (1,960 )   -     (2,084 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
Depreciation and amortization expense   (945 )                  
Segment Performance   (1,069 )   (1,960 )            

Reconciliation of segment performance to loss for the three months ended August 31, 2017:

    Three  
    Months  
    Ended  
    August 31,  
    2017  
    in thousands  
Segment performance   (3,029 )
Stock-based compensation   (383 )
Financial expenses, net   45  
Share in losses of associated companies   (152 )
Loss before income tax   (3,519 )

Geographic, Product and Customer Information

Substantially all the Company's revenues and long-lived assets are in Belgium and South Korea. Net revenues from single customers from the CDMO segment that exceed 10% of total net revenues are:

    Nine Months Ended     Three Months Ended  
    August 31,     August 31,     August 31,     August 31,  
    2018     2017     2018     2017  
    (in thousands)  
Customer A $ 2,339   $ 852   $   -   $ 2,813  
Customer B $ 3,922   $   -   $ 1,651   $   -  
Customer C $ 3,109   $ 809   $ 956   $ 1,904  
Customer D $   -   $ 679   $   -   $ 1,637  
Customer E $   -   $   -   $ 1,100   $   -  
Customer F $   -   $   -   $ 784   $   -  
XML 26 R10.htm IDEA: XBRL DOCUMENT v3.10.0.1
EXERCISE OF CALL OPTIONS OF CURECELL AND ATVIO
9 Months Ended
Aug. 31, 2018
EXERCISE OF CALL OPTIONS OF CURECELL AND ATVIO [Text Block]

NOTE 4 – EXERCISE OF CALL OPTIONS OF CURECELL AND ATVIO

Description of the Transactions

Contemporaneous with the execution of the SPA and the Masthercell Global Stockholders Agreement (as described above), the Company and Masthercell Global entered into a Contribution, Assignment and Assumption Agreement pursuant to which Company contributed to Masthercell Global the Orgenesis’ assets relating to the CDMO business, including the CDMO subsidiaries. In furtherance thereof, Masthercell Global, as Orgenesis’ assignee, acquired all of the issued and outstanding share capital of Atvio, the Company’s Israel based CDMO partner since August 2016, and 94.2% of the share capital of CureCell, the Company’s Korea based CDMO partner since March 2016. Orgenesis exercised the "call option" to which it was entitled under the joint venture agreements with each of these entities to purchase from the former shareholders their equity holding. The consideration for the outstanding share equity in each of Atvio and CureCell consisted solely of Company Common Stock. In respect of the acquisition of Atvio, the Company issued to the former Atvio shareholders an aggregate of 83,964 shares of Company Common Stock. In respect of the acquisition of CureCell, the Company will issue according to valuation to the former CureCell shareholders an aggregate of 202,846 shares of Company Common Stock. Together with MaSTherCell S.A., Atvio and CureCell are directly held subsidiaries under Masthercell Global.

CureCell and Atvio are customer-oriented CDMO companies specializing in cell therapy development for advanced medicinal products.

The exercise of the call options of CureCell and Atvio, pursuant to which the Company obtained effective control over such entities, was accounted for as a business combination. The results of operations of CureCell and Atvio have been included in the Company’s condensed consolidated statements of operations starting from June 28, 2018, the date on which the Company obtained effective control of CureCell and Atvio. The revenues from operations of CureCell and Atvio for the period from June 28, 2018, the acquisition date, to August 31, 2018 was approximately $784 thousands and $41 thousands, respectively.

Fair Value of Consideration Transferred

The Company accounted for the exercise of the call options of CureCell and Atvio as a business combination under the acquisition method of accounting.

The following table summarizes the provisional allocation of purchase price to the fair values of the assets acquired and liabilities assumed as of the transaction date:

            CureCell      
           Total assets acquired:      
           Cash and cash equivalents $ 58  
           Property and equipment, net   1,104  
           Inventory   148  
           Other assets   300  
           Other Intangible assets (a)   3,933  
           Goodwill (b)   3,950  
           Total assets   9,493  
       
Total liabilities assumed:      
           Deferred income from the company and others   1,945  
           Deferred tax   80  
           Fair value of convertible loan from the company   892  
           Non-controlling interests   299  
           Other liabilities   1,487  
Total liabilities   4,703  
Total consideration transferred $ 4,790  
       
Fair value according of shares issued   1,853  
Acquisition date fair value of previously held equity interest   2,937  
Total consideration transferred $ 4,790  

(a)       The allocation of the purchase price to the net assets acquired and liabilities assumed resulted in the recognition of other intangible assets which comprised of: Customer Relationships of $859 and “Know How” of $3,074. These other intangible assets have a useful life of 10 and 12 years, respectively. The useful life of the other intangible assets for amortization purposes was determined considering the period of expected cash flows generated by the assets used to measure the fair value of the intangible assets adjusted as appropriate for the entity-specific factors, including legal, regulatory, contractual, competitive, economic or other factors that may limit the useful life of intangible assets.

The fair value of the Know How was estimated using a relief of royalties’ approach. Under this method, the fair value of the Know How is equal to the royalty fee that the owner of the Know How could profit from if he was to license the Know How out.

Customer Relationships were estimated using a discounted cash flow method with the application of the multi-period excess earnings method. Under this method, an intangible asset’s fair value is equal to the present value of the incremental after-tax cash flows attributable only to the subject intangible asset after deducting contributory asset charges. An income and expenses forecast were built based upon specific intangible asset revenue and expense estimates.

(b)       The primary items that generate goodwill include the value of the synergies between the acquired company and the Company and the acquired assembled workforce, neither of which qualifies for recognition as an intangible asset.

Atvio

The total consideration of Atvio of $890 thousand was attributed mainly to goodwill.

The Company’s purchase price allocation for both companies are preliminary. The fair values of acquired assets and liabilities may be further adjusted as additional information becomes available during the measurement period. Additional information may become available subsequently and may result in changes in the values allocated to various assets and liabilities includes, but is not limited to, any changes in the values allocated to tangible and identified intangible assets acquired and liabilities assumed during the measurement period and may result in material adjustments to goodwill.

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CONVERTIBLE LOAN AGREEMENTS
9 Months Ended
Aug. 31, 2018
CONVERTIBLE LOAN AGREEMENTS [Text Block]

NOTE 5 – CONVERTIBLE LOAN AGREEMENTS

(a)       During the nine months ended August 31, 2018, the Company entered into several unsecured convertible loan agreements with accredited or offshore investors for an aggregate amount of $720 thousand. The loans bear an annual interest rate of 6% and mature in six months or two years from the closing date, unless earlier converted subject to the terms defined in the agreements.

The loans provide that the entire principal amount and accrued interest convert into a Unit, consisting of one share of Common Stock and one three-year warrant exercisable into an additional share of common stock at a per share exercise price of $6.24. In addition, the Company issued to certain investors 40,064 three-year warrants to purchase up to an additional one share of the Company’s Common Stock at a per share exercise price of $6.24.

Since the closing price of the Company's publicly traded stock is greater than the effective conversion price on the closing date, the conversion feature is considered "beneficial" to the holders and equal to $193 thousand. The difference is treated as issued equity and reduces the carrying value of the host debt; the discount is accreted as deemed interest on the debt. The transaction costs for were approximately $89 thousand, out of which $31 thousand are stock-based compensation due to issuance of warrants (See also Note 8(c)). Through August 31, 2018, all convertible loans were converted. See additional information in Note 5b.

(b)       During the nine months ended August 31, 2018, holders of approximately $7.7 million in principal and accrued interest of convertible loans converted these outstanding amounts, into units of the Company’s securities at a deemed per unit conversion price of $6.24, with each unit comprised of: (i) one share of the Company’s Common Stock and (ii) one warrant, exercisable for a period of three years from the date of conversion, for an additional share of Common Stock, at a per share exercise price of $6.24. As a result of these conversions, the holders are entitled to 1,240,972 shares of Common Stock and three-year warrants for an additional 1,240,972 shares of common stock at a per share exercise price of $6.24.

The Company allocated the converted amounts based on the fair value of the warrants and the shares. The table below presents the converted amounts of the proceeds as of the closing date:

    Proceeds  
    allocation  
    (in thousands)  
Warrants component $ 3,037  
Shares component   4,706  
Total $ 7,743  

The fair value of these warrants determined using a Black-Scholes model based on the following assumptions:

  Nine Months Ended
  August 31, 2018
Value of one common share $7.61 - $13.85
Dividend yield 0%
Expected stock price volatility 94.12%- 90.6%
Risk free interest rate 2.43%- 2.29%
Expected term (years) 3

These loans had beneficial conversion features ("BCF"). Therefore, the Company recognized the unamortized BCF as of the conversion date as interest expenses.

(c)       During the nine months ended August 31, 2018, holders of approximately $805 thousand in principal and accrued interest of a convertible loans outstanding from November 2014 and December 2016 converted their outstanding amounts, into shares of the Company’s common stock at a deemed conversion price of $4.80 and $6.24 per share. As a result of this conversion, the Company issued 137,765 shares of common stock.

These loans had beneficial conversion features ("BCF"). Therefore, the Company recognized the unamortized BCF as of the conversion date as interest expenses.

(d)       In March 2018, a former Israel-based consultant exercised warrants issued in November 2016 to purchase shares of the Company’s Common Stock. A related party of such consultant submitted at the same time notice of its intention to convert into shares of the Company’s common stock the principal amount and accrued interest of approximately $396 thousand outstanding under a loan originally advanced to the Company in November 2016. The exercise price of the warrants and conversion price were fixed at $0.52 per share (pre-reverse stock split implemented by the Company in November 2017). There is a significant disagreement between the Company and these two entities as to the number of shares of Common Stock issuable to these entities, and they contend that the number of shares of Common Stock issuable to them should not consider the reverse stock split. The Company rejects these contentions in their entirety and, based on the advice of specially retained counsel, believes that these claims are without legal merit and not made in good faith. The Company intends to vigorously defend its interests and pursue other avenues of legal address. Through its counsel, the Company has advised these entities that unless they withdraw their request within a specified period, the Company will cancel the above referenced agreements and these parties’ right to receive any shares of the Company’s Common Stock. In April 2018, the Company withdrew the agreements and deposited the principal amount and accrued interest of the loan in an escrow account presented as restricted cash in the balance sheet as of August 31, 2018.

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COMMITMENTS
9 Months Ended
Aug. 31, 2018
COMMITMENTS [Text Block]

NOTE 6 – COMMITMENTS

"MSA" with Adva Biotechnology Ltd.

On January 28, 2018, the Company and Adva Biotechnology Ltd. (“Adva”), entered into a Master Services Agreement (“MSA”), under which the Company and/or its affiliates are to provide certain services relating to development of products to Adva, as may be agreed between the parties from time to time. Under the MSA, the Company undertook to provide Adva with in kind funding in the form of materials and services having an aggregate value of $749,900 at the Company’s own cost in accordance with a project schedule and related mutually acceptable project budget. The Company entered into agreement with Atvio Biotech Ltd, its Israeli-based joint venture, to fulfill its obligations pursuant this MSA. As of August 31, 2018, the Company incurred a total expense of $282 thousand.

In consideration for and subject to the fulfillment by the Company of such in-kind funding commitment, Adva agreed that upon completion of the development of the products, the Company and/or its affiliates and Adva shall enter into a supply agreement pursuant to which for a period of eight (8) years following execution of such supply agreement, the Company and/or its affiliates (as applicable) is entitled (on a non-exclusive basis) to purchase the products from Adva at a specified discount pricing from their then standard pricing. The Company and/or its affiliates were also granted a non-exclusive worldwide right to distribute such products, directly or through any of their respective contract development and manufacturing organization (CDMO) service centers during such term. The MSA shall remain in effect for 10 years unless earlier terminated in accordance with its terms.

Grants

On December 18, 2017, MaSTherCell S.A. (“MaSTherCell”), as coordinator of the “Icone” project with a consortium of private and public searchers, received the approval of a new grant from the Walloon Region with a direct financial support of Euro 1 million ($1.2 million) in a program for development of iPS-derived Cortical Neurons. The program started in 2017 for a 4-year period until 2021. After two years, project partners will decide to continue the program upon pre-defined scientific milestone achievements. During the nine months ended August 31, 2018, MaSTherCell received an advance payment of Euro 0.6 million ($0.7 million).

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EQUITY
9 Months Ended
Aug. 31, 2018
EQUITY [Text Block]

NOTE 7 – EQUITY

Financings

a)       In January 2017, the Company entered into definitive agreements with an institutional investor for the private placement of 2,564,115 units of the Company’s securities for aggregate subscription proceeds to the Company of $16 million at $6.24 price per unit. Each unit is comprised of one share of the Company’s Common Stock and a warrant, exercisable over a three-years period from the date of issuance, to purchase one additional share of Common Stock at a per share exercise price of $6.24. The subscription proceeds were payable on a periodic basis through September 2018. The Company subsequently agreed to delay the payments until October 15, 2018. Each periodic payment of subscription proceeds will be evidenced by the Company’s standard securities subscription agreement.

In July 2018, the Company entered into definitive agreements with assignees of the aforementioned institutional investor whereby these assignees remitted $4.6 million in respect of the units available under the original subscription agreement that have not been subscribed for, entitling such investors to 702,307 units, with each unit being comprised of (i) one share of the Company's common stock and (ii) one three-year warrant to purchase up to an additional one share of the Company’s common stock at a per share exercise price of $6.24.

During the nine months ended August 31, 2018 the investor and the assignees remitted to the Company $8,065 thousand, and the Company issued 1,263,204 shares of the Company’s Common Stock and three-year warrants to purchase up to an additional 1,263,204 shares of the Company’s Common Stock at a per share exercise price of $6.24.

The Company allocated the proceeds based on the fair value of the warrants and the shares. The table below presents the allocation of the proceeds as of the closing date:

    Proceeds  
    Allocation  
    (in thousands)  
Warrants component $ 2,923  
Shares component   5,142  
Total $ 8,065  

The fair value of these warrants determined using a Black-Scholes Model based on the following assumptions:

  Nine Months Ended
  August 31, 2018
   
Value of one common share $6.5 -$14.68
Dividend yield 0%
Expected stock price volatility 90.6%- 93.8%
Risk free interest rate 1.99%- 2.73%
Expected term (years) 3

The transaction costs were approximately $328 thousand, out of which $121 thousand are stock-based compensation due to issuance of warrants and shares. See also 8(c).

As of August 31, 2018, the Company has received a total of $12.6 million out of the committed $16 million subscription proceeds.

b)       During the nine months ended August 31, 2018, the Company entered into definitive agreements with accredited and other qualified investors relating to a private placement of 1,237,642 units. Each unit is comprised of (i) one share of the Company’s common stock and (ii) three-year warrant to purchase up to an additional one share of the Company’s Common Stock at a per share exercise price of $6.24, for aggregate proceeds to the Company of approximately $7.7 million.

The Company allocated the proceeds based on the fair value of the warrants and the shares. The table below presents the allocation of the proceeds as of the closing date:

    Proceeds  
    Allocation  
    (in thousands)  
Warrants component $ 2,813  
Shares component   4,910  
Total $ 7,723  

The transaction costs were approximately $349 thousand, out of which $125 thousand are stock-based compensation due to issuance of warrants. See also 8(c).

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STOCK BASED COMPENSATION
9 Months Ended
Aug. 31, 2018
STOCK BASED COMPENSATION [Text Block]

NOTE 8 – STOCK BASED COMPENSATION

a.

Options Granted to employees

Below is a table summarizing the terms of options granted to employees during the nine months ended August 31, 2018:

                      Fair Value at         
    No. of options     Exercise           grant     Expiration  
    granted     price     Vesting period     ( in thousands )     period  
Employee   50,000   $ 4.42     Quarterly over a
period of 1 year
  $ 163     10 years  
Employees   30,500   $ 8.91     Quarterly over a
period of 2 years
  $ 192     10 years  
Employee   250,000   $ 8.36     Semi-annual over a
period of 1 year
  $ 1,488     10 years  
MaSTherCell's
employees
  70,300   $ 8.43     Quarterly over a
period of 2 years
  $ 464     10 years  
MaSTherCell's
employees
  123,550   $ 8.43     Quarterly over a
period of 4 years
  $ 925     10 years  

The fair value of these option grants is based on the following assumptions:

  Nine Months Ended
  August 31, 2018
Value of one common share $4.42 - $8.85
Dividend yield 0%
Expected stock price volatility 97%- 91%
Risk free interest rate 2.96%- 2.11%
Expected term (years) 5 - 7

b.

Options Granted to non-employees

Below is a table summarizing all the options granted to consultants and service providers during the nine months ended August 31, 2018:

                      Fair value at        
    No. of options     Exercise           grant     Expiration  
    granted     price     Vesting period     ( in thousands )     period  
Non-employee   5,200     4.42     Over six months   $ 36     10 years  
Non-employee   13,725   $ 4.42,8.34     Immediately   $ 82     10 years  
Non-employee   8,333   $ 8.43     Annual over a period
of 5 year
  $ 57     10 years  

The fair value of these option grants is based on the following assumptions:

  Nine Months Ended
  August 31, 2018
Value of one common share $8.3,$4.42
Dividend yield 0%
Expected stock price volatility 91%- 98%
Risk free interest rate $2.33 -$2.83
Expected term (years) 4.5 - 10

c.

Shares and Warrants Granted to non-employees

1)    During the nine months ended August 31, 2018, the Company granted to several consultants 50,938 warrants with each exercisable at $6.24 to $15.41 per share for three years as a success fee with respect to the issuance of the convertible loans and part of the private placement. The fair value of those warrants as of the date of grant using the Black-Scholes valuation model was $248 thousand.

2)    In December 2017, the Company entered into investor relations services, marketing and related services agreement. Under the terms of the agreement, the Company agreed to grant the consultant 100,000 shares of restricted common stock, out of which the first 25,000 shares will vest after 30 days from the signing date, and 75,000 shares are to vest monthly over 15 months commencing February 2018. As of August 31, 2018, 60,000 shares were vested. The fair value of the shares as of the date of grant was $738 thousand.

3)    In December 2017, the Company entered into an investor relations services, marketing and related services agreement. Under the terms of the agreement, the Company agreed to grant the consultant 95,000 shares of restricted common stock, of which the first 25,000 shares will vest after 30 days from the signing date, and 70,000 shares are to vest monthly over 14 months commencing February 2018. As of August 31, 2018, 60,000 shares were vested. The fair value of the shares as of the date of grant was $701 thousand.

4)    In January 2018, the Company entered into a consulting agreement with a financial advisor for a period of one year. Under the terms of the agreement, the consultant was entitled to receive $60 thousand and 19,000 units of the Company securities. Each unit is comprised of (i) one share of the Company’s common stock and (ii) a three-year warrant to purchase up to an additional one share of the Company’s Common Stock at a per share exercise price of $6.24. The fair value of the units as of the date of grant was $171 thousand, out of which $62 thousand reflect the fair value of the warrants using the Black-Scholes valuation model. In July 2018, the board approved an additional issuance of 6,629 shares and three-year warrants to purchase up to 6,629 shares of the Company’s Common Stock at a per share exercise price of $6.24. The fair value of the units as of the date of grant was $88 thousand.

5)    During the nine months ended August 31, 2018, investors exercised 136,646 warrants into 136,646 shares of the Company’s Common Stock, for aggregate proceeds of $853 thousand.

6)    On July 6, 2018, the Compensation Committee approved the issuance of 13,558 warrants to two consultants to purchase 13,558 shares of Common Stock, exercisable at a per share exercise price of $11.19.

XML 31 R15.htm IDEA: XBRL DOCUMENT v3.10.0.1
LOSS PER SHARE
9 Months Ended
Aug. 31, 2018
LOSS PER SHARE [Text Block]

NOTE 9 – LOSS PER SHARE

The following table sets forth the calculation of basic and diluted loss per share for the period indicated:

    Three Months Ended     Nine Months Ended  
    August 31,     August 31,  
    2018     2017     2018     2017  
    (in thousands, except per share data)  
                         
Basic:                        
Loss for the period $ 5,070   $ 3,940   $ 13,295   $ 12,557  
   Weighted average number of common shares outstanding   14,355,430     10,279,180     12,774,802     9,477,211  
   Loss per common share $ (0.35 ) $ (0.38 ) $ (1.04 ) $ (1.32 )
Diluted :                        
Loss for the period $ 5,070   $ 3,940   $ 13,295   $ 12,557  
Changes in fair value of embedded
     derivative and interest expense on 
     convertible loans
  -     238     -     137  
Loss for the period $ 5,070   $ 4,178   $ 13,295   $ 12,694  
                         
Weighted average number of shares
     used in the computation of basic and diluted
     loss per share
  14,355,430     10,279,180     12,774,802     9,477,211  
Number of dilutive shares related to convertible loans   -     106,319     -     26,042  
Weighted average number of common shares outstanding   14,355,430     10,385,499     12,774,802     9,503,253  
                         
Loss per common share $ (0.35 ) $ (0.40 ) $ (1.04 ) $ (1.34 )

Diluted loss per share does not include 7,919,874 shares underlying outstanding options and warrants and 201,557 shares upon conversion of convertible notes for the nine months ended August 31, 2018, because the effect of their inclusion in the computation would be anti-dilutive.

Diluted loss per share does not include 4,375,856 shares underlying outstanding options and warrants and 2,462,598 shares upon conversion of convertible notes for the three and nine months ended August 31, 2017, because the effect of their inclusion in the computation would be anti-dilutive.

XML 32 R16.htm IDEA: XBRL DOCUMENT v3.10.0.1
FAIR VALUE PRESENTATION
9 Months Ended
Aug. 31, 2018
FAIR VALUE PRESENTATION [Text Block]

NOTE 10 - FAIR VALUE PRESENTATION

The Company measures fair value and discloses fair value measurements for financial assets and liabilities. Fair value is based on the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. The accounting standard establishes a fair value hierarchy that prioritizes observable and unobservable inputs used to measure fair value into three broad levels, which are described below:

Level 1: Quoted prices (unadjusted) in active markets that are accessible at the measurement date for assets or liabilities. The fair value hierarchy gives the highest priority to Level 1 inputs.
Level 2: Observable inputs that are based on inputs not quoted on active markets but corroborated by market data.
Level 3: Unobservable inputs are used when little or no market data is available. The fair value hierarchy gives the lowest priority to Level 3 inputs.
   
  In determining fair value, the Company utilizes valuation techniques that maximize the use of observable inputs and minimize the use of unobservable inputs, to the extent possible, and considers credit risk in its assessment of fair value.

As of August 31, 2018, and November 30, 2017, the Company’s assets and liabilities that are measured at fair value and classified as level 3 fair value are as follows (in thousands):

    August 31,     November 30,  
    2018     2017  
    Level 3     Level 3  
Embedded derivatives convertible loans*(1) $   -   $ 37  
Call/Put option derivatives $   -   $ (339 )

*

The embedded derivative is presented in the Company's balance sheets on a combined basis with the related host contract (the convertible loans).


  (1)

The fair value is determined by using a Black-Scholes Model.

The fair value of the convertible bonds is equal to their principal amount and the aggregate accrued interest.

The table below sets forth a summary of the changes in the fair value of the Company’s financial liabilities classified as Level 3 for the nine months ended August 31, 2018:

    Embedded     Put Option     
    Derivatives     Derivative     
             
Balance at beginning of the period $ 37   $ (339 )
Repayment   (14 )   -  
Changes in fair value during the period   (23 )   49  
Option disposal (See Note 4)   -     290  
Balance at end of the period $   -   $   -  

(*) There were no transfers to Level 3 during the nine months ended August 31, 2018.

The table below sets forth a summary of the changes in the fair value of the Company’s financial assets and liabilities classified as Level 3 for the year ended November 30, 2017:

    Embedded     Convertible     Put Option  
    Derivatives     Bonds     Derivative  
                   
Balance at beginning of the year $ 240   $ 1,818   $ 273  
Repayment   (876 )   (1,827 )      
Changes in fair value during the period   662     22     (612 )
Translation adjustments   11     (13 )      
Balance at end of the year $ 37   $   -   $ (339 )

(*) There were no transfers to Level 3 during the twelve months ended November 30, 2017.

XML 33 R17.htm IDEA: XBRL DOCUMENT v3.10.0.1
OTHER INCOME - NET
9 Months Ended
Aug. 31, 2018
OTHER INCOME - NET [Text Block]

NOTE 11 – OTHER INCOME - NET

Includes net gain on remeasurement of previously equity interest in Atvio and CureCell to acquisition date fair value in the amount of $4,509 and transaction costs related to GPP agreement in the amount of $1.5 million.

XML 34 R18.htm IDEA: XBRL DOCUMENT v3.10.0.1
SUBSEQUENT EVENTS
9 Months Ended
Aug. 31, 2018
SUBSEQUENT EVENTS [Text Block]

NOTE 12 - SUBSEQUENT EVENTS

In October 2018, the Company raised $3.4 million from the institutional investor referred to in Note 7 entitling such investor to 550,481 shares of Common Stock and three-year warrants for an additional 550,481 shares. Following this remittance and those referred to in Note 7, the Company has received, as of October 12, 2018, a total of $16 million out of the committed $16 million subscription proceeds under such agreement.

XML 35 R19.htm IDEA: XBRL DOCUMENT v3.10.0.1
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables)
9 Months Ended
Aug. 31, 2018
Condensed Balance Sheet [Table Text Block]
    August 31, 2017  
          Impact        
    As reported     of        
    Previously     adoption     As revised  
    In thousands  
                   
Additional paid-in capital $ 50,518   $ 3,849   $ 54,367  
Accumulated deficit $ (41,345 ) $ (2,965 ) $ (44,310 )
Total equity $ 11,251   $ 873   $ 12,124  
Condensed Income Statement [Table Text Block]
    Nine months ended August 31, 2017     Three months ended August 31, 2017  
    As                 As              
    reported     Impact of     As     reported     Impact of     As  
    Previously     adoption     revised     Previously     adoption     revised  
    In thousands  
                                     
                                     
Financial expenses (income), net $ 1,488   $ 1,046   $ 2,534   $ (2,032 ) $ 1,987   $ (45 )
Loss before income taxes $ 11,018   $ 1,046   $ 12,064   $ 1,532   $ 1,987   $ 3,519  
Net loss $ 11,511   $ 1,046   $ 12,557   $ 1,953   $ 1,987   $ 3,940  
XML 36 R20.htm IDEA: XBRL DOCUMENT v3.10.0.1
SEGMENT INFORMATION (Tables)
3 Months Ended 9 Months Ended
Aug. 31, 2018
Aug. 31, 2017
Aug. 31, 2018
Aug. 31, 2017
Schedule of Segment Information [Table Text Block]
                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Revenues from external customers $ 8,092   $ 83   $ (1,945 ) $ 6,230 *  
Cost of revenues   (3,908 )   -     539     (3,369 )
Segment gross profit (loss)   4,184     83     (1,406 )   2,861  
Research and development expenses, net   (245 )   (3,298 )   1,406     (1,737 )
Operating expenses   (1,712 )   (1,453 )         (3,165 )
Other expenses   (88 )   -           (88 )
Segment operating profit (loss)   2,139     (4,268 )   -     (2,129 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
     Depreciation and amortization   (567 )   (3 )            
Segment performance   1,572     (4,271 )            
                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Net revenues from external customers $ 2,956           (394 )   2,562  
Cost of revenues   (1,439 )         95     (1,344 )
Segment gross profit (loss)   1,517           (299 )   1,218  
Research and development expenses, net         (688 )   299     (389 )
Operating expenses   (1,641 )   (1,272 )         (2,913 )
Segment operating profit (loss)   (124 )   (1,960 )   -     (2,084 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
Depreciation and amortization expense   (945 )                  
Segment Performance   (1,069 )   (1,960 )            
                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Revenues from external customers $ 15,807   $ 83   $ (3,037 ) $ 12,853 *  
Cost of revenues   (7,826 )   -     927     (6,899 )
Segment gross profit (loss)   7,981     83     (2,110 )   5,954  
Research and development expenses, net   (245 )   (4,764 )   2,110     (2,899 )
Operating expenses   (3,895 )   (4,448 )         (8,343 )
Other income   228     -           228  
Segment operating profit (loss)   4,069     (9,129 )   -     (5,060 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
     Depreciation and amortization   (1,807 )   (7 )            
Segment performance   2,262     (9,136 )            
                Corporate        
                and        
    CDMO     CT     Eliminations     Consolidated  
    (in thousands)  
Revenues from external customers $ 7,705   $   -   $ (993 ) $ 6,712  
Cost of revenues   (4,358 )         403     (3,955 )
Segment gross profit (loss)   3,347           (590 )   2,757  
Research and development expenses, net         (1,932 )   590     (1,342 )
Operating expenses   (916 )   (6,060 )         (6,976 )
Segment operating profit (loss)   2,431     (7,992 )   -     (5,561 )
Adjustments to presentation of segment                        
Adjusted EBIT                        
Depreciation and amortization expenses   (2,145 )   (7 )            
Segment Performance   286     (7,999 )            
Schedule Of Reconciliation of Segment Performance [Table Text Block]
    Three Months  
    Ended August  
    31, 2018  
    in thousands  
  Segment performance   (2,699 )
Stock-based compensation   (955 )
Financial expenses, net   (1,070 )
Share in losses of associated companies   (202 )
Net gain on remeasurement of previously 
     equity interest in Atvio and CureCell to 
     acquisition date fair value
  4,509  
Transaction expenses related to GPP agreement   (1,500 )
Loss before income tax $ (1,917 )
    Three  
    Months  
    Ended  
    August 31,  
    2017  
    in thousands  
Segment performance   (3,029 )
Stock-based compensation   (383 )
Financial expenses, net   45  
Share in losses of associated companies   (152 )
Loss before income tax   (3,519 )
    Nine months  
    Ended August  
    31, 2018  
    in thousands  
Segment performance   (6,874 )
Stock-based compensation   (2,782 )
Financial expenses, net   (3,164 )
Net gain on remeasurement of previously
     equity interest in Atvio and CureCell to 
     acquisition date fair value
  4,509  
Transaction expenses related to GPP agreement   (1,500 )
Share in losses of associated companies   (732 )
Loss before income tax $ (10,543 )
    Nine Months  
    Ended  
    August 31,  
    2017  
    in thousands  
Segment performance   (7,713 )
Stock-based compensation   (1,469 )
Financial expenses, net   (2,534 )
Share in losses of associated companies   (348 )
Loss before income tax   (12,064 )
Schedule of Revenues from Major Customers [Table Text Block]    
    Nine Months Ended     Three Months Ended  
    August 31,     August 31,     August 31,     August 31,  
    2018     2017     2018     2017  
    (in thousands)  
Customer A $ 2,339   $ 852   $   -   $ 2,813  
Customer B $ 3,922   $   -   $ 1,651   $   -  
Customer C $ 3,109   $ 809   $ 956   $ 1,904  
Customer D $   -   $ 679   $   -   $ 1,637  
Customer E $   -   $   -   $ 1,100   $   -  
Customer F $   -   $   -   $ 784   $   -  
 
XML 37 R21.htm IDEA: XBRL DOCUMENT v3.10.0.1
EXERCISE OF CALL OPTIONS OF CURECELL AND ATVIO (Tables)
9 Months Ended
Aug. 31, 2018
Business Combination, Segment Allocation [Table Text Block]
            CureCell      
           Total assets acquired:      
           Cash and cash equivalents $ 58  
           Property and equipment, net   1,104  
           Inventory   148  
           Other assets   300  
           Other Intangible assets (a)   3,933  
           Goodwill (b)   3,950  
           Total assets   9,493  
       
Total liabilities assumed:      
           Deferred income from the company and others   1,945  
           Deferred tax   80  
           Fair value of convertible loan from the company   892  
           Non-controlling interests   299  
           Other liabilities   1,487  
Total liabilities   4,703  
Total consideration transferred $ 4,790  
       
Fair value according of shares issued   1,853  
Acquisition date fair value of previously held equity interest   2,937  
Total consideration transferred $ 4,790  
XML 38 R22.htm IDEA: XBRL DOCUMENT v3.10.0.1
CONVERTIBLE LOAN AGREEMENTS (Tables)
9 Months Ended
Aug. 31, 2018
Schedule of Fair Value of Loan Agreement [Table Text Block]
    Proceeds  
    allocation  
    (in thousands)  
Warrants component $ 3,037  
Shares component   4,706  
Total $ 7,743  
Schedule of Convertible Loan Agreements, Valuation Assumptions [Table Text Block]
  Nine Months Ended
  August 31, 2018
Value of one common share $7.61 - $13.85
Dividend yield 0%
Expected stock price volatility 94.12%- 90.6%
Risk free interest rate 2.43%- 2.29%
Expected term (years) 3
XML 39 R23.htm IDEA: XBRL DOCUMENT v3.10.0.1
EQUITY (Tables)
9 Months Ended 12 Months Ended
Aug. 31, 2018
Nov. 30, 2017
Schedule of Fair Value of Instruments for Financing [Table Text Block]
    Proceeds  
    Allocation  
    (in thousands)  
Warrants component $ 2,923  
Shares component   5,142  
Total $ 8,065  
    Proceeds  
    Allocation  
    (in thousands)  
Warrants component $ 2,813  
Shares component   4,910  
Total $ 7,723  
Schedule of Stockholders' Equity Note, Warrants or Rights, Valuation Assumptions [Table Text Block]
  Nine Months Ended
  August 31, 2018
   
Value of one common share $6.5 -$14.68
Dividend yield 0%
Expected stock price volatility 90.6%- 93.8%
Risk free interest rate 1.99%- 2.73%
Expected term (years) 3
 
XML 40 R24.htm IDEA: XBRL DOCUMENT v3.10.0.1
STOCK BASED COMPENSATION (Tables)
9 Months Ended
Aug. 31, 2018
Options Granted to Employees [Member]  
Employee Stock Ownership Plan (ESOP) Disclosures [Table Text Block]
                      Fair Value at         
    No. of options     Exercise           grant     Expiration  
    granted     price     Vesting period     ( in thousands )     period  
Employee   50,000   $ 4.42     Quarterly over a
period of 1 year
  $ 163     10 years  
Employees   30,500   $ 8.91     Quarterly over a
period of 2 years
  $ 192     10 years  
Employee   250,000   $ 8.36     Semi-annual over a
period of 1 year
  $ 1,488     10 years  
MaSTherCell's
employees
  70,300   $ 8.43     Quarterly over a
period of 2 years
  $ 464     10 years  
MaSTherCell's
employees
  123,550   $ 8.43     Quarterly over a
period of 4 years
  $ 925     10 years  
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
  Nine Months Ended
  August 31, 2018
Value of one common share $4.42 - $8.85
Dividend yield 0%
Expected stock price volatility 97%- 91%
Risk free interest rate 2.96%- 2.11%
Expected term (years) 5 - 7
Options Granted to Non- Employees [Member]  
Schedule of Share-based Compensation, Stock Options Granted to Consultants [Table Text Block]
                      Fair value at        
    No. of options     Exercise           grant     Expiration  
    granted     price     Vesting period     ( in thousands )     period  
Non-employee   5,200     4.42     Over six months   $ 36     10 years  
Non-employee   13,725   $ 4.42,8.34     Immediately   $ 82     10 years  
Non-employee   8,333   $ 8.43     Annual over a period
of 5 year
  $ 57     10 years  
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
  Nine Months Ended
  August 31, 2018
Value of one common share $8.3,$4.42
Dividend yield 0%
Expected stock price volatility 91%- 98%
Risk free interest rate $2.33 -$2.83
Expected term (years) 4.5 - 10
XML 41 R25.htm IDEA: XBRL DOCUMENT v3.10.0.1
LOSS PER SHARE (Tables)
9 Months Ended
Aug. 31, 2018
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
    Three Months Ended     Nine Months Ended  
    August 31,     August 31,  
    2018     2017     2018     2017  
    (in thousands, except per share data)  
                         
Basic:                        
Loss for the period $ 5,070   $ 3,940   $ 13,295   $ 12,557  
   Weighted average number of common shares outstanding   14,355,430     10,279,180     12,774,802     9,477,211  
   Loss per common share $ (0.35 ) $ (0.38 ) $ (1.04 ) $ (1.32 )
Diluted :                        
Loss for the period $ 5,070   $ 3,940   $ 13,295   $ 12,557  
Changes in fair value of embedded
     derivative and interest expense on 
     convertible loans
  -     238     -     137  
Loss for the period $ 5,070   $ 4,178   $ 13,295   $ 12,694  
                         
Weighted average number of shares
     used in the computation of basic and diluted
     loss per share
  14,355,430     10,279,180     12,774,802     9,477,211  
Number of dilutive shares related to convertible loans   -     106,319     -     26,042  
Weighted average number of common shares outstanding   14,355,430     10,385,499     12,774,802     9,503,253  
                         
Loss per common share $ (0.35 ) $ (0.40 ) $ (1.04 ) $ (1.34 )
XML 42 R26.htm IDEA: XBRL DOCUMENT v3.10.0.1
FAIR VALUE PRESENTATION (Tables)
9 Months Ended 12 Months Ended
Aug. 31, 2018
Nov. 30, 2017
Schedule of Assets and Liabilities at Fair Value [Table Text Block]
    August 31,     November 30,  
    2018     2017  
    Level 3     Level 3  
Embedded derivatives convertible loans*(1) $   -   $ 37  
Call/Put option derivatives $   -   $ (339 )
 
Schedule of Fair Value of Financial Liabilities, Activity [Table Text Block]
    Embedded     Put Option     
    Derivatives     Derivative     
             
Balance at beginning of the period $ 37   $ (339 )
Repayment   (14 )   -  
Changes in fair value during the period   (23 )   49  
Option disposal (See Note 4)   -     290  
Balance at end of the period $   -   $   -  
    Embedded     Convertible     Put Option  
    Derivatives     Bonds     Derivative  
                   
Balance at beginning of the year $ 240   $ 1,818   $ 273  
Repayment   (876 )   (1,827 )      
Changes in fair value during the period   662     22     (612 )
Translation adjustments   11     (13 )      
Balance at end of the year $ 37   $   -   $ (339 )
XML 43 R27.htm IDEA: XBRL DOCUMENT v3.10.0.1
GENERAL AND BASIS OF PRESENTATION (Narrative) (Details)
9 Months Ended
Aug. 31, 2018
USD ($)
mo
d
shares
General And Basis Of Presentation 1 1
General And Basis Of Presentation 2 | shares 12
General And Basis Of Presentation 3 | shares 378,000
General And Basis Of Presentation 4 37.80%
General And Basis Of Presentation 5 $ 25,000,000
General And Basis Of Presentation 6 $ 13,200,000
General And Basis Of Presentation 7 | shares 622,000
General And Basis Of Presentation 8 62.20%
General And Basis Of Presentation 9 $ 11,800,000
General And Basis Of Presentation 10 1,500,000
General And Basis Of Presentation 11 1,500,000
General And Basis Of Presentation 12 10,300,000
General And Basis Of Presentation 13 6,600,000
General And Basis Of Presentation 14 $ 13,200,000
General And Basis Of Presentation 15 | shares 378,000
General And Basis Of Presentation 16 $ 50,000,000
General And Basis Of Presentation 17 (3.5)
General And Basis Of Presentation 18 $ 250,000,000
General And Basis Of Presentation 19 | shares 2,704,247
General And Basis Of Presentation 20 19.99%
General And Basis Of Presentation 21 $ 250,000
General And Basis Of Presentation 22 | mo 12
General And Basis Of Presentation 23 5.00%
General And Basis Of Presentation 24 | mo 12
General And Basis Of Presentation 25 $ 2,000,000
General And Basis Of Presentation 26 | mo 12
General And Basis Of Presentation 27 $ 500,000
General And Basis Of Presentation 28 $ 2,000,000
General And Basis Of Presentation 29 | mo 12
General And Basis Of Presentation 30 2.00%
General And Basis Of Presentation 31 $ 57,400,000
General And Basis Of Presentation 32 11,500,000
General And Basis Of Presentation 33 16,500,000
General And Basis Of Presentation 34 8,100,000
General And Basis Of Presentation 35 3,400,000
General And Basis Of Presentation 36 $ 2,900,000
General And Basis Of Presentation 37 | d 45
General And Basis Of Presentation 38 $ 50,000
General And Basis Of Presentation 39 5.00%
General And Basis Of Presentation 40 | d 90
General And Basis Of Presentation 41 $ 80,000
General And Basis Of Presentation 42 8.00%
General And Basis Of Presentation 43 49.00%
General And Basis Of Presentation 44 51.00%
General And Basis Of Presentation 45 $ 10,000,000
General And Basis Of Presentation 46 10,000,000
General And Basis Of Presentation 47 $ 15,000,000
General And Basis Of Presentation 48 | mo 12
General And Basis Of Presentation 49 51.00%
General And Basis Of Presentation 50 $ 10,000,000
General And Basis Of Presentation 51 $ 10,000,000
General And Basis Of Presentation 52 10.00%
General And Basis Of Presentation 53 $ 5,000,000
General And Basis Of Presentation 54 | d 15
General And Basis Of Presentation 55 $ 6.24
General And Basis Of Presentation 56 6.24
General And Basis Of Presentation 57 5,000,000
General And Basis Of Presentation 58 $ 10,000,000
General And Basis Of Presentation 59 | mo 12
General And Basis Of Presentation 60 50.00%
General And Basis Of Presentation 61 $ 5,000,000
XML 44 R28.htm IDEA: XBRL DOCUMENT v3.10.0.1
SEGMENT INFORMATION (Narrative) (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Aug. 31, 2018
Aug. 31, 2017
Aug. 31, 2018
Aug. 31, 2017
Revenues $ 6,230 $ 2,562 $ 12,853 $ 6,712
Services [Member]        
Revenues 4,473   9,493  
Goods sold [Member]        
Revenues $ 1,757   $ 3,360  
XML 45 R29.htm IDEA: XBRL DOCUMENT v3.10.0.1
EXERCISE OF CALL OPTIONS OF CURECELL AND ATVIO (Narrative) (Details)
9 Months Ended
Aug. 31, 2018
USD ($)
yr
shares
Exercise Of Call Options Of Curecell And Atvio 1 94.20%
Exercise Of Call Options Of Curecell And Atvio 2 | shares 83,964
Exercise Of Call Options Of Curecell And Atvio 3 | shares 202,846
Exercise Of Call Options Of Curecell And Atvio 4 $ 784,000
Exercise Of Call Options Of Curecell And Atvio 5 41,000
Exercise Of Call Options Of Curecell And Atvio 6 859
Exercise Of Call Options Of Curecell And Atvio 7 $ 3,074
Exercise Of Call Options Of Curecell And Atvio 8 10
Exercise Of Call Options Of Curecell And Atvio 9 | yr 12
Exercise Of Call Options Of Curecell And Atvio 10 $ 890,000
XML 46 R30.htm IDEA: XBRL DOCUMENT v3.10.0.1
CONVERTIBLE LOAN AGREEMENTS (Narrative) (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 9 Months Ended
Mar. 31, 2018
Aug. 31, 2018
Aug. 31, 2017
Feb. 28, 2018
Proceeds from issuance of convertible loans (net of transaction costs)   $ 720 $ 4,932  
Debt Instrument, Interest Rate, Stated Percentage   6.00%    
Debt Instrument, Convertible, Conversion Price $ 0.52 $ 6.24   $ 6.24
Class of Warrant or Right, Grants in Period, Net of Forfeitures   40,064    
Class of Warrant or Right, Grants in Period, Exercise Price   $ 6.24    
Debt Instrument, Convertible, Beneficial Conversion Feature   $ 193    
Convertible Debt Transaction Cost   89    
Adjustment of Warrants Granted for Services   31    
Debt Conversion, Converted Instrument and Accrued Interest, Amount $ 396 $ 7,700    
Debt Conversion, Converted Instrument, Shares Issued   1,240,972    
Debt Conversion, Converted Instrument, Warrants or Options Issued   1,240,972    
Convertible loans outstanding from November 2014 and December 2016 [Member]        
Debt Conversion, Converted Instrument and Accrued Interest, Amount   $ 805,000    
Debt Conversion, Converted Instrument, Warrants or Options Issued   137,765    
Convertible loans outstanding from November 2014 [Member]        
Debt Instrument, Convertible, Conversion Price   $ 4.80    
Convertible loans outstanding from December 2016 [Member]        
Debt Instrument, Convertible, Conversion Price   $ 6.24    
XML 47 R31.htm IDEA: XBRL DOCUMENT v3.10.0.1
COMMITMENTS (Narrative) (Details)
€ in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Dec. 31, 2017
USD ($)
Dec. 31, 2017
EUR (€)
Aug. 31, 2018
USD ($)
Aug. 31, 2017
USD ($)
Aug. 31, 2018
USD ($)
Aug. 31, 2017
USD ($)
Jan. 31, 2018
USD ($)
Dec. 18, 2017
USD ($)
Dec. 18, 2017
EUR (€)
Commitment             $ 749,900    
Expenses         $ 282,000        
Grants Receivable, Noncurrent               $ 1,200,000 € 1.0
Revenues     $ 6,230,000 $ 2,562,000 $ 12,853,000 $ 6,712,000      
Revenue from grants [Member]                  
Revenues $ 700,000 € 0.6              
XML 48 R32.htm IDEA: XBRL DOCUMENT v3.10.0.1
EQUITY (Narrative) (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 9 Months Ended
Jul. 31, 2018
Jan. 31, 2017
Aug. 31, 2018
Class of Warrant or Right, Grants in Period, Net of Forfeitures     40,064
Class of Warrant or Right, Grants in Period, Exercise Price     $ 6.24
Definitive agreements with an institutional investor [Member]      
Units Issued During Period, Units 702,307 2,564,115  
Common Stock Shares Subscriptions $ 4,600 $ 16,000 $ 16,000
Units Issued During Period, Exercise Price $ 6.24 $ 6.24  
Proceeds from Issuance of Private Placement     $ 8,065
Stock Issued During Period, Shares, Issued for Cash     1,263,204
Class of Warrant or Right, Grants in Period, Net of Forfeitures     1,263,204
Class of Warrant or Right, Grants in Period, Exercise Price   $ 6.24 $ 6.24
Payments of Transaction Costs     $ 328
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures     121
Cash Received From Subscription     $ 12,600
Definitive agreements with accredited and other qualified investors [Member]      
Units Issued During Period, Units     1,237,642
Units Issued During Period, Exercise Price     $ 6.24
Proceeds from Issuance of Private Placement     $ 7,700
Payments of Transaction Costs     349
Warrants Granted During Period, Value     $ 125
XML 49 R33.htm IDEA: XBRL DOCUMENT v3.10.0.1
STOCK BASED COMPENSATION (Narrative) (Details)
9 Months Ended
Aug. 31, 2018
USD ($)
mo
d
$ / shares
shares
Stock Based Compensation 1 50,938
Stock Based Compensation 2 | $ $ 6.24
Stock Based Compensation 3 | $ / shares $ 15.41
Stock Based Compensation 4 | $ $ 248,000
Stock Based Compensation 5 100,000
Stock Based Compensation 6 25,000
Stock Based Compensation 7 | d 30
Stock Based Compensation 8 75,000
Stock Based Compensation 9 | mo 15
Stock Based Compensation 10 60,000
Stock Based Compensation 11 | $ $ 738,000
Stock Based Compensation 12 95,000
Stock Based Compensation 13 25,000
Stock Based Compensation 14 | d 30
Stock Based Compensation 15 70,000
Stock Based Compensation 16 | mo 14
Stock Based Compensation 17 60,000
Stock Based Compensation 18 | $ $ 701,000
Stock Based Compensation 19 | $ $ 60,000
Stock Based Compensation 20 19,000
Stock Based Compensation 21 | $ $ 6.24
Stock Based Compensation 22 | $ 171,000
Stock Based Compensation 23 | $ $ 62,000
Stock Based Compensation 24 6,629
Stock Based Compensation 25 6,629
Stock Based Compensation 26 | $ $ 6.24
Stock Based Compensation 27 | $ $ 88,000
Stock Based Compensation 28 136,646
Stock Based Compensation 29 136,646
Stock Based Compensation 30 | $ $ 853,000
Stock Based Compensation 31 13,558
Stock Based Compensation 32 13,558
Stock Based Compensation 33 | $ $ 11.19
XML 50 R34.htm IDEA: XBRL DOCUMENT v3.10.0.1
LOSS PER SHARE (Narrative) (Details) - shares
3 Months Ended 9 Months Ended
Aug. 31, 2017
Aug. 31, 2018
Aug. 31, 2017
Options and warrants [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount 4,375,856 7,919,874  
Shares [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount   201,557 2,462,598
XML 51 R35.htm IDEA: XBRL DOCUMENT v3.10.0.1
OTHER INCOME - NET (Narrative) (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Aug. 31, 2018
Aug. 31, 2018
Aug. 31, 2017
Net gain on remeasurement of previously equity interest in Atvio and CureCell to acquisition date fair value $ 4,509 $ 4,509 $ 0
Transaction expenses related to GPP agreement $ 1,500 $ 1,500  
XML 52 R36.htm IDEA: XBRL DOCUMENT v3.10.0.1
SUBSEQUENT EVENTS (Narrative) (Details)
$ in Millions
9 Months Ended
Aug. 31, 2018
USD ($)
shares
Subsequent Events 1 $ 3.4
Subsequent Events 2 | shares 550,481
Subsequent Events 3 | shares 550,481
Subsequent Events 4 $ 16.0
Subsequent Events 5 $ 16.0
XML 53 R37.htm IDEA: XBRL DOCUMENT v3.10.0.1
Condensed Balance Sheet (Details) - USD ($)
$ in Thousands
Aug. 31, 2018
Nov. 30, 2017
Aug. 31, 2017
Additional paid-in capital $ 80,889 $ 55,334  
Accumulated deficit (57,415) (44,120)  
Total equity $ 29,625 $ 14,123  
As reported Previously [Member]      
Additional paid-in capital     $ 50,518
Accumulated deficit     (41,345)
Total equity     11,251
Impact of adoption [Member]      
Additional paid-in capital     3,849
Accumulated deficit     (2,965)
Total equity     873
As revised [Member]      
Additional paid-in capital     54,367
Accumulated deficit     (44,310)
Total equity     $ 12,124
XML 54 R38.htm IDEA: XBRL DOCUMENT v3.10.0.1
Condensed Income Statement (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Aug. 31, 2018
Aug. 31, 2017
Aug. 31, 2018
Aug. 31, 2017
Financial expenses, net $ 1,070 $ (45) $ 3,164 $ 2,534
Loss before income taxes 1,917 3,519 10,543 12,064
Net loss $ 5,070 3,940 $ 13,295 12,557
As reported Previously [Member]        
Financial expenses, net   (2,032)   1,488
Loss before income taxes   1,532   11,018
Net loss   1,953   11,511
Impact of adoption [Member]        
Financial expenses, net   1,987   1,046
Loss before income taxes   1,987   1,046
Net loss   1,987   1,046
As revised [Member]        
Financial expenses, net   (45)   2,534
Loss before income taxes   3,519   12,064
Net loss   $ 3,940   $ 12,557
XML 55 R39.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Segment Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Aug. 31, 2018
Aug. 31, 2017
Aug. 31, 2018
Aug. 31, 2017
Revenues $ 6,230 $ 2,562 $ 12,853 $ 6,712
Cost of revenues (3,381) (1,867) (7,220) (4,900)
Gross profit (loss) 2,849 695 5,633 1,812
Research and development expenses, net (1,902) (500) (3,456) (1,906)
Operating profit (loss) (645) (3,412) (6,647) (9,182)
Depreciation and amortization expense     (1,833) (1,874)
Segment Performance 2,699 3,029 6,874 7,713
CDMO [Member]        
Revenues 8,092 2,956 15,807 7,705
Cost of revenues (3,908) (1,439) (7,826) (4,358)
Gross profit (loss) 4,184 1,517 7,981 3,347
Research and development expenses, net (245)   (245)  
Operating expenses (1,712) (1,641) (3,895) (916)
Other Income (Expense) (88)   228  
Operating profit (loss) 2,139 (124) 4,069 2,431
Depreciation and amortization expense (567) (945) (1,807) (2,145)
Segment Performance 1,572 (1,069) 2,262 286
CTB [Member]        
Revenues 83   83 0
Cost of revenues 0   0  
Gross profit (loss) 83   83  
Research and development expenses, net (3,298) (688) (4,764) (1,932)
Operating expenses (1,453) (1,272) (4,448) (6,060)
Other Income (Expense) 0   0  
Operating profit (loss) (4,268) (1,960) (9,129) (7,992)
Depreciation and amortization expense (3)   (7) (7)
Segment Performance (4,271) (1,960) (9,136) (7,999)
Corporate and Eliminations [Member]        
Revenues (1,945) (394) (3,037) (993)
Cost of revenues 539 95 927 403
Gross profit (loss) (1,406) (299) (2,110) (590)
Research and development expenses, net 1,406 299 2,110 590
Operating profit (loss) 0 0 0 0
Consolidated [Member]        
Revenues 6,230 2,562 12,853 6,712
Cost of revenues (3,369) (1,344) (6,899) (3,955)
Gross profit (loss) 2,861 1,218 5,954 2,757
Research and development expenses, net (1,737) (389) (2,899) (1,342)
Operating expenses (3,165) (2,913) (8,343) (6,976)
Other Income (Expense) (88)   228  
Operating profit (loss) $ (2,129) $ (2,084) $ (5,060) $ (5,561)
XML 56 R40.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule Of Reconciliation of Segment Performance (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Aug. 31, 2018
Aug. 31, 2017
Aug. 31, 2018
Aug. 31, 2017
Segment Performance $ (2,699) $ (3,029) $ (6,874) $ (7,713)
Stock-based compensation (955) (383) (2,782) (1,469)
Financial income (expenses), net (1,070) 45 (3,164) (2,534)
Net gain on remeasurement of previously equity interest in Atvio and CureCell to acquisition date fair value 4,509   4,509 0
Transaction expenses related to GPP agreement (1,500)   (1,500)  
Share in losses of associated companies (202) (152) (732) (348)
Loss before income tax $ (1,917) $ (3,519) $ (10,543) $ (12,064)
XML 57 R41.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Revenues from Major Customers (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Aug. 31, 2018
Aug. 31, 2017
Aug. 31, 2018
Aug. 31, 2017
Revenues $ 6,230 $ 2,562 $ 12,853 $ 6,712
Customer A [Member]        
Revenues 0 2,813 2,339 852
Customer B [Member]        
Revenues 1,651 0 3,922 0
Customer C [Member]        
Revenues 956 1,904 3,109 809
Customer D [Member]        
Revenues 0 1,637 0 679
Customer E [Member]        
Revenues 1,100 0 0 0
Customer F [Member]        
Revenues $ 784 $ 0 $ 0 $ 0
XML 58 R42.htm IDEA: XBRL DOCUMENT v3.10.0.1
Business Combination, Segment Allocation (Details) - USD ($)
$ in Thousands
9 Months Ended
Aug. 31, 2018
Nov. 30, 2017
Goodwill $ 15,632 $ 10,684
CureCell [Member]    
Cash and cash equivalents 58  
Property and equipment, net 1,104  
Inventory 148  
Other assets 300  
Other Intangible assets 3,933  
Goodwill 3,950  
Total assets 9,493  
Deferred income from the company and others 1,945  
Deferred taxes 80  
Fair value of convertible loan from the company 892  
Non-controlling interests 299  
Other liabilities 1,487  
Total liabilities 4,703  
Total consideration transferred 4,790  
Fair value according of shares issued 1,853  
Acquisition date fair value of previously held equity interest $ 2,937  
XML 59 R43.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Fair Value of Loan Agreement (Details)
$ in Thousands
Aug. 31, 2018
USD ($)
Warrants component $ 3,037
Shares component 4,706
Total $ 7,743
XML 60 R44.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Convertible Loan Agreements, Valuation Assumptions (Details)
9 Months Ended
Aug. 31, 2018
$ / shares
Dividend yield 0.00%
Expected term (years) 3 years
Minimum [Member]  
Value of one common share $ 7.61
Expected stock price volatility 90.60%
Risk free interest rate 2.29%
Maximum [Member]  
Value of one common share $ 13.85
Expected stock price volatility 94.12%
Risk free interest rate 2.43%
XML 61 R45.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Fair Value of Instruments for Financing (Details) - USD ($)
$ in Thousands
Aug. 31, 2018
Nov. 30, 2017
Warrants component $ 2,923 $ 2,813
Shares component 5,142 4,910
Total $ 8,065 $ 7,723
XML 62 R46.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Stockholders' Equity Note, Warrants or Rights, Valuation Assumptions (Details)
9 Months Ended
Aug. 31, 2018
$ / shares
Class of Warrant or Right, Valuation Method, Expected Dividend Rate 0.00%
Class of Warrant or Right, Valuation Method, Expected Term 3 years
Minimum [Member]  
Class of Warrant or Right, Valuation Method, Value of one common share $ 6.5
Class of Warrant or Right, Valuation Method, Expected Volatility Rate 90.60%
Class of Warrant or Right, Valuation Method, Risk Free Interest Rate 1.99%
Maximum [Member]  
Class of Warrant or Right, Valuation Method, Value of one common share $ 14.68
Class of Warrant or Right, Valuation Method, Expected Volatility Rate 93.80%
Class of Warrant or Right, Valuation Method, Risk Free Interest Rate 2.73%
XML 63 R47.htm IDEA: XBRL DOCUMENT v3.10.0.1
Employee Stock Ownership Plan (ESOP) Disclosures (Details) - Options Granted to Employees [Member]
$ / shares in Units, $ in Thousands
9 Months Ended
Aug. 31, 2018
USD ($)
$ / shares
shares
Employee 1 [Member]  
No. of options granted | shares 50,000
Exercise price | $ / shares $ 4.42
Vesting period 1 year
Fair value at grant | $ $ 163
Expiration period 10 years
Employee 2 [Member]  
No. of options granted | shares 30,500
Exercise price | $ / shares $ 8.91
Vesting period 2 years
Fair value at grant | $ $ 192
Expiration period 10 years
Employee 3 [Member]  
No. of options granted | shares 250,000
Exercise price | $ / shares $ 8.36
Vesting period 1 year
Fair value at grant | $ $ 1,488
Expiration period 10 years
MaSTherCell's Employees 1 [Member]  
No. of options granted | shares 70,300
Exercise price | $ / shares $ 8.43
Vesting period 2 years
Fair value at grant | $ $ 464
Expiration period 10 years
MaSTherCell's Employees 2 [Member]  
No. of options granted | shares 123,550
Exercise price | $ / shares $ 8.43
Vesting period 4 years
Fair value at grant | $ $ 925
Expiration period 10 years
XML 64 R48.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Share-based Compensation, Stock Options Granted to Consultants (Details) - Options Granted to Non- Employees [Member]
$ / shares in Units, $ in Thousands
9 Months Ended
Aug. 31, 2018
USD ($)
$ / shares
shares
Non-employee 1 [Member]  
No. of options granted | shares 5,200
Exercise price $ 4.42
Fair value at grant | $ $ 36
Expiration period 10 years
Non-employee 2 [Member]  
No. of options granted | shares 13,725
Fair value at grant | $ $ 82
Expiration period 10 years
Non-employee 2 [Member] | Minimum [Member]  
Exercise price $ 4.42
Non-employee 2 [Member] | Maximum [Member]  
Exercise price $ 8.34
Non-employee 3 [Member]  
No. of options granted | shares 8,333
Exercise price $ 8.43
Vesting period 5 years
Fair value at grant | $ $ 57
Expiration period 10 years
XML 65 R49.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions (Details)
9 Months Ended
Aug. 31, 2018
$ / shares
Options Granted to Employees [Member]  
Dividend yield 0.00%
Options Granted to Non- Employees [Member]  
Dividend yield 0.00%
Minimum [Member] | Options Granted to Employees [Member]  
Value of one common share $ 4.42
Expected stock price volatility 91.00%
Risk free interest rate 2.11%
Expected term (years) 5 years
Minimum [Member] | Options Granted to Non- Employees [Member]  
Value of one common share $ 4.42
Expected stock price volatility 91.00%
Risk free interest rate 2.33%
Expected term (years) 4 years 6 months
Maximum [Member] | Options Granted to Employees [Member]  
Value of one common share $ 8.85
Expected stock price volatility 97.00%
Risk free interest rate 2.96%
Expected term (years) 7 years
Maximum [Member] | Options Granted to Non- Employees [Member]  
Value of one common share $ 8.3
Expected stock price volatility 98.00%
Risk free interest rate 2.83%
Expected term (years) 10 years
XML 66 R50.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Earnings Per Share, Basic and Diluted (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 9 Months Ended
Aug. 31, 2018
Aug. 31, 2017
Aug. 31, 2018
Aug. 31, 2017
Net loss $ 5,070 $ 3,940 $ 13,295 $ 12,557
Weighted average number of common shares outstanding 14,355,430 10,279,180 12,774,802 9,477,211
Loss per common share $ (0.35) $ (0.38) $ (1.04) $ (1.32)
Loss for the period $ 5,070 $ 3,940 $ 13,295 $ 12,557
Changes in fair value of embedded derivative and interest expense on convertible loans 0 238 0 137
Loss for the period $ 5,070 $ 4,178 $ 13,295 $ 12,694
Number of dilutive shares related to convertible loans 0 106,319 0 26,042
Weighted average number of common shares outstanding 14,355,430 10,385,499 12,774,802 9,503,253
Loss per common share $ (0.35) $ (0.40) $ (1.04) $ (1.34)
XML 67 R51.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Assets and Liabilities at Fair Value (Details) - USD ($)
$ in Thousands
Aug. 31, 2018
Nov. 30, 2017
Embedded derivatives convertible loans $ 0 $ 37
Call/Put option derivatives $ 0 $ (339)
XML 68 R52.htm IDEA: XBRL DOCUMENT v3.10.0.1
Schedule of Fair Value of Financial Liabilities, Activity (Details) - USD ($)
$ in Thousands
9 Months Ended 12 Months Ended
Aug. 31, 2018
Nov. 30, 2017
Embedded derivatives, beginning balance $ 37  
Embedded derivatives, ending balance 0 $ 37
Embedded Derivative [Member]    
Embedded derivatives, beginning balance 37 240
Repayment (14) (876)
Changes in fair value during the period (23) 662
Option disposal 0  
Translation adjustments   11
Embedded derivatives, ending balance 0 37
Convertible Bonds [Member]    
Convertible bonds, beginning balance 0 1,818
Repayment   (1,827)
Changes in fair value during the period   22
Translation adjustments   (13)
Convertible bonds, ending balance   0
Put Option Derivative [Member]    
Put option derivative, beginning balance (339) 273
Repayment 0  
Changes in fair value during the period 49 (612)
Option disposal 290  
Put option derivative, ending balance $ 0 $ (339)
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