Stockholders' Equity - Stock Option Activity (Details) - USD ($) $ / shares in Units, $ in Thousands	6 Months Ended		12 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Number of Options
Outstanding balance at the beginning of the period (in shares)	3,477,439
Granted (in shares)	3,043,789	0
Exercised (in shares)	(286,733)
Forfeited (in shares)	(227,384)
Expired (in shares)	(42,138)
Outstanding balance at the end of the period (in shares)	5,964,973		3,477,439
Exercisable at the end of the period (in shares)	3,187,768
Weighted-Average Exercise Price per Share
Outstanding balance at the beginning of the period (in dollars per share)	$ 36.13
Granted (in dollars per share)	10.76
Exercised (in dollars per share)	3.12
Forfeited (in dollars per share)	14.89
Expired (in dollars per share)	60.02
Outstanding balance at the end of the period (in dollars per share)	25.41		$ 36.13
Exercisable at the end of the period (in dollars per share)	$ 34.69
Weighted Average Remaining Contractual Term
Outstanding balance (in years)	6 years 6 months 29 days		3 years 10 months 13 days
Granted (in years)	8 years 10 months 9 days
Exercised (in years)	7 days
Weighted-average remaining contractual term of options exercisable at the end of the period (in years)	3 years 11 months 4 days
Aggregate Intrinsic Value
Outstanding balance at the end of the period	$ 1,806		$ 16,246
Exercisable at the end of the period	$ 1,802