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Stock and employee benefit plans - Schedule of stock option activity for employees and nonemployees (Details) - Stock options - USD ($)
$ / shares in Units, shares in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2020
Dec. 31, 2019
Shares    
Outstanding at the beginning of the period (in shares) 1,323  
Granted (in shares) 66  
Exercised (in shares) 0  
Canceled (in shares) (19)  
Outstanding at the end of the period (in shares) 1,370 1,323
Exercisable at the end of the period (in shares) 585  
Weighted-Average Exercise Price    
Outstanding at the beginning of the period (in dollars per share) $ 11.65  
Granted (in dollars per share) 1.99  
Exercised (in dollars per share) 0.00  
Canceled (in dollars per share) 4.85  
Outstanding at the end of the period (in dollars per share) 11.28 $ 11.65
Exercisable at the end of the period (in dollars per share) $ 18.90  
Weighted-Average Remaining Contractual Term (years)    
Outstanding at the beginning/end of the period 7 years 10 months 25 days
Exercisable at the end of the period 6 years 8 months 20 days  
Aggregate Intrinsic Value    
Outstanding at the end of the period (in dollars) $ 0 $ 0
Exercisable at the end of the period (in dollars) $ 0