X0306 4 2019-06-10 0 0001175505 FIVE PRIME THERAPEUTICS INC FPRX 0001456849 Dhingra Kapil 111 OYSTER POINT BOULEVARD SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Stock Option (right to buy) 6.09 2019-06-10 4 A 0 15000 0.00 A 2029-06-09 Common Stock 15000 15000 D This option will vest in its entirety on the earlier to occur of (i) June 10, 2020 or (ii) the day before the 2020 annual meeting of stockholders of Five Prime Therapeutics, Inc. (the "Company"), subject to the reporting person's continued service to the Company through such vest date. /s/ Francis Sarena, Attorney-in-fact 2019-06-12