X0306 4 2017-05-10 0 0001374690 ZAFGEN, INC. ZFGN 0001456750 KIM DENNIS D C/O ZAFGEN, INC. 175 PORTLAND STREET, 4TH FLOOR BOSTON MA 02114 0 1 0 0 Chief Medical Officer Common Stock 2017-05-10 4 P 0 200 4.40 A 1643 D Common Stock 2017-05-11 4 P 0 9800 4.40 A 11443 D Includes 646 shares acquired under Zafgen, Inc.'s 2014 Employee Stock Purchase Plan (the "Plan") on January 1, 2015, 699 shares acquired under the Plan on July 1, 2015 and 98 shares acquired under the Plan on January 1, 2016. /s/ Laurie Burlingame, Attorney-in-Fact 2017-05-11