0001456228-21-000005.txt : 20210312 0001456228-21-000005.hdr.sgml : 20210312 20210312102606 ACCESSION NUMBER: 0001456228-21-000005 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20201231 FILED AS OF DATE: 20210312 DATE AS OF CHANGE: 20210312 EFFECTIVENESS DATE: 20210312 FILER: COMPANY DATA: COMPANY CONFORMED NAME: DekaBank Deutsche Girozentrale CENTRAL INDEX KEY: 0001456228 IRS NUMBER: 000000000 STATE OF INCORPORATION: 2M FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-13421 FILM NUMBER: 21735827 BUSINESS ADDRESS: STREET 1: MAINZER LANDSTRASSE 16 CITY: FRANKFURT STATE: 2M ZIP: 60325 BUSINESS PHONE: 49.69.7147-0 MAIL ADDRESS: STREET 1: MAINZER LANDSTRASSE 16 CITY: FRANKFURT STATE: 2M ZIP: 60325 FORMER COMPANY: FORMER CONFORMED NAME: DekaBank Deutsche Girozentrale, Frankfurt DATE OF NAME CHANGE: 20090212 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001456228 XXXXXXXX 12-31-2020 12-31-2020 DekaBank Deutsche Girozentrale

MAINZER LANDSTRASSE 16 FRANKFURT 2M 60325

13F HOLDINGS REPORT 028-13421 N Stefan Frauendorf 00496971475460 Stefan Frauendorf Frankfurt am Main 2M 03-12-2021 2 2361 26637396 false 1 0001456191 028-13420 Deka Investment GmbH 2 0001551738 028-16160 Deka Vermoegensmanagement GmbH INFORMATION TABLE 2 infotable.xml 10X GENOMICS INC CL A COM 88025U109 496 3499 SH DFND 1 3499 0 0 2U INC COM 90214J101 2593 66500 SH DFND 2 66500 0 0 3M CO COM 88579Y101 54056 309065 SH DFND 1 309065 0 0 3M CO COM 88579Y101 45380 259459 SH DFND 2 259459 0 0 3M CO COM 88579Y101 6 36 SH SOLE 36 0 0 51JOB INC SPONSORED ADS 316827104 149 2160 SH DFND 1 2160 0 0 A10 NETWORKS INC COM 002121101 455 47750 SH DFND 1 47750 0 0 ABBOTT LABS COM 002824100 147371 1349998 SH DFND 1 1349998 0 0 ABBOTT LABS COM 002824100 174560 1599065 SH DFND 2 1599065 0 0 ABBOTT LABS COM 002824100 12 109 SH SOLE 109 0 0 ABBVIE INC COM 00287Y109 175718 1670477 SH DFND 1 1670477 0 0 ABBVIE INC COM 00287Y109 63231 601108 SH DFND 2 601108 0 0 ABBVIE INC COM 00287Y109 13 127 SH SOLE 127 0 0 ABIOMED INC COM 003654100 1665 5198 SH DFND 1 5198 0 0 ABIOMED INC COM 003654100 1 3 SH SOLE 3 0 0 ABSOLUTE SOFTWARE CORP COM 00386B109 824 67287 SH DFND 1 67287 0 0 AC IMMUNE SA SHS H00263105 140 27000 SH DFND 2 27000 0 0 ACACIA COMMUNICATIONS INC COM 00401C108 145 2000 SH DFND 1 2000 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 3426 64300 SH DFND 2 64300 0 0 ACCELERON PHARMA INC COM 00434H108 2980 23750 SH DFND 2 23750 0 0 ACCENTURE PLC IRELAND SHS CLASS A G1151C101 107466 416001 SH DFND 1 416001 0 0 ACCENTURE PLC IRELAND SHS CLASS A G1151C101 45724 176997 SH DFND 2 176997 0 0 ACCENTURE PLC IRELAND SHS CLASS A G1151C101 89 345 SH SOLE 345 0 0 ACTIVISION BLIZZARD INC COM 00507V109 57608 627577 SH DFND 1 627577 0 0 ACTIVISION BLIZZARD INC COM 00507V109 17411 189680 SH DFND 2 189680 0 0 ACTIVISION BLIZZARD INC COM 00507V109 4 48 SH SOLE 48 0 0 ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 215 42000 SH DFND 2 42000 0 0 ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 2539 43000 SH DFND 2 43000 0 0 ADOBE SYSTEMS INCORPORATED COM 00724F101 125459 247691 SH DFND 1 247691 0 0 ADOBE SYSTEMS INCORPORATED COM 00724F101 67013 132302 SH DFND 2 132302 0 0 ADOBE SYSTEMS INCORPORATED COM 00724F101 18 36 SH SOLE 36 0 0 ADOBE SYSTEMS INCORPORATED COM 00724F101 0 1400 SH Call DFND 1 1400 0 0 ADVANCE AUTO PARTS INC COM 00751Y106 1121 7173 SH DFND 1 7173 0 0 ADVANCE AUTO PARTS INC COM 00751Y106 1 5 SH SOLE 5 0 0 ADVANCED DRAIN SYS INC DEL COM 00790R104 495 6000 SH DFND 1 6000 0 0 ADVANCED DRAIN SYS INC DEL COM 00790R104 247 3000 SH DFND 2 3000 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 380 32500 SH DFND 2 32500 0 0 AECOM COM 00766T100 447 9220 SH DFND 1 9220 0 0 AERCAP HOLDINGS NV SHS N00985106 120 2695 SH DFND 1 2695 0 0 AERCAP HOLDINGS NV SHS N00985106 0 2 SH SOLE 2 0 0 AERIE PHARMACEUTICALS INC COM 00771V108 161 12100 SH DFND 2 12100 0 0 AES CORP COM 00130H105 819 35408 SH DFND 1 35408 0 0 AES CORP COM 00130H105 0 19 SH SOLE 19 0 0 AFFILIATED MANAGERS GROUP IN COM 008252108 225 2260 SH DFND 1 2260 0 0 AFFIMED N V COM N01045108 584 100000 SH DFND 2 100000 0 0 AFLAC INC COM 001055102 5427 123572 SH DFND 1 123572 0 0 AFLAC INC COM 001055102 902 20544 SH DFND 2 20544 0 0 AFLAC INC COM 001055102 3 63 SH SOLE 63 0 0 AGCO CORP COM 001084102 3377 33550 SH DFND 1 33550 0 0 AGILENT TECHNOLOGIES INC COM 00846U101 24293 207002 SH DFND 1 207002 0 0 AGILENT TECHNOLOGIES INC COM 00846U101 33593 286249 SH DFND 2 286249 0 0 AGILENT TECHNOLOGIES INC COM 00846U101 3 24 SH SOLE 24 0 0 AGIOS PHARMACEUTICALS INC COM 00847X104 1492 33900 SH DFND 2 33900 0 0 AGNC INVT CORP COM 00123Q104 889 58433 SH DFND 1 58433 0 0 AGNC INVT CORP COM 00123Q104 0 18 SH SOLE 18 0 0 AGNICO EAGLE MINES LTD COM 008474108 3035 42456 SH DFND 1 42456 0 0 AGNICO EAGLE MINES LTD COM 008474108 4912 68700 SH DFND 2 68700 0 0 AGREE REALTY CORP COM 008492100 3288 50913 SH DFND 1 50913 0 0 AIR PRODS & CHEMS INC COM 009158106 13674 49625 SH DFND 1 49625 0 0 AIR PRODS & CHEMS INC COM 009158106 19341 70188 SH DFND 2 70188 0 0 AIR PRODS & CHEMS INC COM 009158106 0 1 SH SOLE 1 0 0 AKAMAI TECHNOLOGIES INC COM 00971T101 10791 101229 SH DFND 1 101229 0 0 AKAMAI TECHNOLOGIES INC COM 00971T101 25053 235012 SH DFND 2 235012 0 0 AKAMAI TECHNOLOGIES INC COM 00971T101 1 10 SH SOLE 10 0 0 AKEBIA THERAPEUTICS INC COM 00972D105 279 102100 SH DFND 2 102100 0 0 AKERO THERAPEUTICS INC COM 00973Y108 301 12000 SH DFND 2 12000 0 0 AKOUOS INC COM 00973J101 213 11000 SH DFND 2 11000 0 0 ALASKA AIR GROUP INC COM 011659109 21 412 SH DFND 1 412 0 0 ALBEMARLE CORP COM 012653101 2773 18943 SH DFND 1 18943 0 0 ALBEMARLE CORP COM 012653101 1 5 SH SOLE 5 0 0 ALBIREO PHARMA INC COM 01345P106 1254 33900 SH DFND 2 33900 0 0 ALCON AG ORD SHS H01301128 24888 373529 SH DFND 1 373529 0 0 ALCON AG ORD SHS H01301128 2587 38823 SH DFND 2 38823 0 0 ALECTOR INC COM 014442107 336 22200 SH DFND 2 22200 0 0 ALEXANDER & BALDWIN INC NEW COM 014491104 745 43596 SH DFND 1 43596 0 0 ALEXANDRIA REAL ESTATE EQ IN COM 015271109 3660 20808 SH DFND 1 20808 0 0 ALEXANDRIA REAL ESTATE EQ IN COM 015271109 598 3400 SH DFND 2 3400 0 0 ALEXANDRIA REAL ESTATE EQ IN COM 015271109 1 3 SH SOLE 3 0 0 ALEXION PHARMACEUTICALS INC COM 015351109 10312 65777 SH DFND 1 65777 0 0 ALEXION PHARMACEUTICALS INC COM 015351109 25420 162151 SH DFND 2 162151 0 0 ALEXION PHARMACEUTICALS INC COM 015351109 3 19 SH SOLE 19 0 0 ALGONQUIN PWR UTILS CORP COM 015857105 8276 507818 SH DFND 1 507818 0 0 ALGONQUIN PWR UTILS CORP COM 015857105 570 35000 SH DFND 2 35000 0 0 ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 138145 567167 SH DFND 1 567167 0 0 ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 36424 149541 SH DFND 2 149541 0 0 ALIGN TECHNOLOGY INC COM 016255101 7669 14690 SH DFND 1 14690 0 0 ALIGN TECHNOLOGY INC COM 016255101 1305 2500 SH DFND 2 2500 0 0 ALIGN TECHNOLOGY INC COM 016255101 3 5 SH SOLE 5 0 0 ALKERMES PLC SHS G01767105 764 36550 SH DFND 2 36550 0 0 ALLAKOS INC COM 01671P100 2379 16670 SH DFND 2 16670 0 0 ALLEGHANY CORP DEL COM 017175100 684 1148 SH DFND 1 1148 0 0 ALLEGHANY CORP DEL COM 017175100 1 1 SH SOLE 1 0 0 ALLEGION PLC ORD SHS G0176J109 3172 27874 SH DFND 1 27874 0 0 ALLEGION PLC ORD SHS G0176J109 2784 24470 SH DFND 2 24470 0 0 ALLEGION PLC ORD SHS G0176J109 1 7 SH SOLE 7 0 0 ALLIANT ENERGY CORP COM 018802108 1778 35258 SH DFND 1 35258 0 0 ALLIANT ENERGY CORP COM 018802108 0 3 SH SOLE 3 0 0 ALLISON TRANSMISSION HLDGS I COM 01973R101 106 2500 SH DFND 1 2500 0 0 ALLISON TRANSMISSION HLDGS I COM 01973R101 800 18800 SH DFND 2 18800 0 0 ALLOGENE THERAPEUTICS INC COM 019770106 1237 45900 SH DFND 2 45900 0 0 ALLOVIR INC COM 019818103 703 19000 SH DFND 2 19000 0 0 ALLSTATE CORP COM 020002101 19144 177853 SH DFND 1 177853 0 0 ALLSTATE CORP COM 020002101 16063 149229 SH DFND 2 149229 0 0 ALLSTATE CORP COM 020002101 3 30 SH SOLE 30 0 0 ALLY FINL INC COM 02005N100 3079 88142 SH DFND 1 88142 0 0 ALLY FINL INC COM 02005N100 912 26100 SH DFND 2 26100 0 0 ALLY FINL INC COM 02005N100 1 29 SH SOLE 29 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 1449 11135 SH DFND 1 11135 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 7872 60510 SH DFND 2 60510 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 0 3 SH SOLE 3 0 0 ALPHABET INC CAP STK CL A 02079K305 479778 271523 SH DFND 1 271523 0 0 ALPHABET INC CAP STK CL A 02079K305 212553 120291 SH DFND 2 120291 0 0 ALPHABET INC CAP STK CL C 02079K107 102696 58095 SH DFND 1 58095 0 0 ALPHABET INC CAP STK CL C 02079K107 6986 3952 SH DFND 2 3952 0 0 ALPS ETF TR REIT DIVIDE DOGS 00162Q106 55 4200 SH DFND 1 4200 0 0 ALTICE USA INC CL A 02156K103 737 19462 SH DFND 1 19462 0 0 ALTRIA GROUP INC COM 02209S103 9951 242629 SH DFND 1 242629 0 0 ALTRIA GROUP INC COM 02209S103 619 15100 SH DFND 2 15100 0 0 ALX ONCOLOGY HLDGS INC COM 00166B105 886 10500 SH DFND 2 10500 0 0 AMALGAMATED BK NEW YORK N Y CLASS A 022663108 476 35500 SH DFND 1 35500 0 0 AMALGAMATED BK NEW YORK N Y CLASS A 022663108 7361 548959 SH DFND 2 548959 0 0 AMARIN CORP PLC SPONS ADR NEW 023111206 697 144600 SH DFND 2 144600 0 0 AMAZON COM INC COM 023135106 537711 160791 SH DFND 1 160791 0 0 AMAZON COM INC COM 023135106 182969 54713 SH DFND 2 54713 0 0 AMAZON COM INC COM 023135106 17 5 SH SOLE 5 0 0 AMBARELLA INC SHS G037AX101 880 10000 SH DFND 1 10000 0 0 AMBEV SA SPONSORED ADR 02319V103 78 26000 SH DFND 1 26000 0 0 AMC NETWORKS INC CL A 00164V103 402 11600 SH DFND 1 11600 0 0 AMC NETWORKS INC CL A 00164V103 1028 29637 SH DFND 2 29637 0 0 AMCI ACQUISITION CORP CLASS A 00165R101 1258 80000 SH DFND 1 80000 0 0 AMDOCS LTD SHS G02602103 602 8815 SH DFND 1 8815 0 0 AMDOCS LTD SHS G02602103 5525 80930 SH DFND 2 80930 0 0 AMEDISYS INC COM 023436108 2823 9807 SH DFND 1 9807 0 0 AMEDISYS INC COM 023436108 658 2285 SH DFND 2 2285 0 0 AMERCO COM 023586100 396 899 SH DFND 1 899 0 0 AMERCO COM 023586100 0 1 SH SOLE 1 0 0 AMEREN CORP COM 023608102 64819 849864 SH DFND 1 849864 0 0 AMERESCO INC CL A 02361E108 6052 120000 SH DFND 1 120000 0 0 AMERICAN AIRLS GROUP INC COM 02376R102 27 1693 SH DFND 1 1693 0 0 AMERICAN CAMPUS CMNTYS INC COM 024835100 1744 41701 SH DFND 1 41701 0 0 AMERICAN ELEC PWR CO INC COM 025537101 42882 528810 SH DFND 1 528810 0 0 AMERICAN ELEC PWR CO INC COM 025537101 310 3824 SH DFND 2 3824 0 0 AMERICAN EXPRESS CO COM 025816109 12320 104174 SH DFND 1 104174 0 0 AMERICAN EXPRESS CO COM 025816109 325 2750 SH DFND 2 2750 0 0 AMERICAN EXPRESS CO COM 025816109 6 54 SH SOLE 54 0 0 AMERICAN FINL GROUP INC OHIO COM 025932104 490 5731 SH DFND 1 5731 0 0 AMERICAN FINL GROUP INC OHIO COM 025932104 1 7 SH SOLE 7 0 0 AMERICAN HOMES 4 RENT CL A 02665T306 2381 80985 SH DFND 1 80985 0 0 AMERICAN INTL GROUP INC COM NEW 026874784 3488 93948 SH DFND 1 93948 0 0 AMERICAN INTL GROUP INC COM NEW 026874784 3 82 SH SOLE 82 0 0 AMERICAN TOWER CORP NEW COM 03027X100 17081 75685 SH DFND 1 75685 0 0 AMERICAN TOWER CORP NEW COM 03027X100 1783 7900 SH DFND 2 7900 0 0 AMERICAN TOWER CORP NEW COM 03027X100 7 29 SH SOLE 29 0 0 AMERICAN WELL CORP CL A 03044L105 1536 56900 SH DFND 1 56900 0 0 AMERICAN WTR WKS CO INC NEW COM 030420103 25017 166123 SH DFND 1 166123 0 0 AMERICAN WTR WKS CO INC NEW COM 030420103 9698 64400 SH DFND 2 64400 0 0 AMERICAN WTR WKS CO INC NEW COM 030420103 2 12 SH SOLE 12 0 0 AMERICOLD RLTY TR COM 03064D108 2439 67913 SH DFND 1 67913 0 0 AMERICOLD RLTY TR COM 03064D108 22 600 SH DFND 2 600 0 0 AMERIPRISE FINL INC COM 03076C106 8074 42621 SH DFND 1 42621 0 0 AMERIPRISE FINL INC COM 03076C106 3 14 SH SOLE 14 0 0 AMERISOURCEBERGEN CORP COM 03073E105 3953 40678 SH DFND 1 40678 0 0 AMERISOURCEBERGEN CORP COM 03073E105 2659 27365 SH DFND 2 27365 0 0 AMERISOURCEBERGEN CORP COM 03073E105 1 13 SH SOLE 13 0 0 AMETEK INC COM 031100100 13013 109805 SH DFND 1 109805 0 0 AMETEK INC COM 031100100 9031 76201 SH DFND 2 76201 0 0 AMETEK INC COM 031100100 2 14 SH SOLE 14 0 0 AMGEN INC COM 031162100 141187 617453 SH DFND 1 617453 0 0 AMGEN INC COM 031162100 102268 447249 SH DFND 2 447249 0 0 AMGEN INC COM 031162100 11 48 SH SOLE 48 0 0 AMICUS THERAPEUTICS INC COM 03152W109 1943 86300 SH DFND 2 86300 0 0 AMPHASTAR PHARMACEUTICALS IN COM 03209R103 299 14900 SH DFND 2 14900 0 0 AMPHENOL CORP NEW CL A 032095101 5491 42923 SH DFND 1 42923 0 0 AMPHENOL CORP NEW CL A 032095101 3 20 SH SOLE 20 0 0 ANALOG DEVICES INC COM 032654105 16148 112640 SH DFND 1 112640 0 0 ANALOG DEVICES INC COM 032654105 8699 60679 SH DFND 2 60679 0 0 ANALOG DEVICES INC COM 032654105 4 25 SH SOLE 25 0 0 ANAPLAN INC COM 03272L108 1356 18500 SH DFND 1 18500 0 0 ANAPTYSBIO INC COM 032724106 100 4700 SH DFND 2 4700 0 0 ANGLOGOLD ASHANTI LIMITED SPONSORED ADR 035128206 57 2500 SH DFND 1 2500 0 0 ANGLOGOLD ASHANTI LIMITED SPONSORED ADR 035128206 835 36500 SH DFND 2 36500 0 0 ANI PHARMACEUTICALS INC COM 00182C103 97 3450 SH DFND 2 3450 0 0 ANNALY CAPITAL MANAGEMENT IN COM 035710409 1148 139871 SH DFND 1 139871 0 0 ANNALY CAPITAL MANAGEMENT IN COM 035710409 1 144 SH SOLE 144 0 0 ANNEXON INC COM 03589W102 339 12000 SH DFND 2 12000 0 0 ANSYS INC COM 03662Q105 3289 9055 SH DFND 1 9055 0 0 ANSYS INC COM 03662Q105 50097 137909 SH DFND 2 137909 0 0 ANSYS INC COM 03662Q105 2 6 SH SOLE 6 0 0 ANTHEM INC COM 036752103 10267 32847 SH DFND 1 32847 0 0 ANTHEM INC COM 036752103 17455 55840 SH DFND 2 55840 0 0 ANTHEM INC COM 036752103 6 20 SH SOLE 20 0 0 AON PLC SHS CL A G0403H108 6199 30540 SH DFND 1 30540 0 0 AON PLC SHS CL A G0403H108 8525 42000 SH DFND 2 42000 0 0 AON PLC SHS CL A G0403H108 3 16 SH SOLE 16 0 0 APACHE CORP COM 037411105 31 2157 SH DFND 1 2157 0 0 APARTMENT INCOME REIT CORP COM 03750L109 98 2587 SH DFND 1 2587 0 0 APARTMENT INVT & MGMT CO CL A 03748R747 13 2587 SH DFND 1 2587 0 0 APELLIS PHARMACEUTICALS INC COM 03753U106 2769 50700 SH DFND 2 50700 0 0 APOLLO GLOBAL MGMT INC COM CL A 03768E105 713 14790 SH DFND 1 14790 0 0 APPLE HOSPITALITY REIT INC COM NEW 03784Y200 1615 125006 SH DFND 1 125006 0 0 APPLE INC COM 037833100 742811 5471525 SH DFND 1 5471525 0 0 APPLE INC COM 037833100 163454 1204000 SH DFND 2 1204000 0 0 APPLIED MATLS INC COM 038222105 22073 262636 SH DFND 1 262636 0 0 APPLIED MATLS INC COM 038222105 2782 33097 SH DFND 2 33097 0 0 APPLIED MATLS INC COM 038222105 6 69 SH SOLE 69 0 0 APPLIED MOLECULAR TRANS INC COM 03824M109 370 11000 SH DFND 2 11000 0 0 APPLIED THERAPEUTICS INC COM 03828A101 151 7000 SH DFND 2 7000 0 0 APREA THERAPEUTICS INC COM 03836J102 35 7000 SH DFND 2 7000 0 0 APTARGROUP INC COM 038336103 1079 7833 SH DFND 1 7833 0 0 APTARGROUP INC COM 038336103 152 1102 SH DFND 2 1102 0 0 ARAMARK COM 03852U106 693 18407 SH DFND 1 18407 0 0 ARAMARK COM 03852U106 1 14 SH SOLE 14 0 0 ARBUTUS BIOPHARMA CORP COM 03879J100 892 250000 SH DFND 1 250000 0 0 ARCH CAP GROUP LTD ORD G0450A105 1416 39982 SH DFND 1 39982 0 0 ARCHER DANIELS MIDLAND CO COM 039483102 3776 76438 SH DFND 1 76438 0 0 ARCHER DANIELS MIDLAND CO COM 039483102 2 37 SH SOLE 37 0 0 ARCTURUS THERAPEUTICS HLDGS COM 03969T109 343 8100 SH DFND 2 8100 0 0 ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 358 12400 SH DFND 2 12400 0 0 ARDELYX INC COM 039697107 196 30000 SH DFND 2 30000 0 0 ARENA PHARMACEUTICALS INC COM NEW 040047607 2089 26950 SH DFND 2 26950 0 0 ARGENX SE SPONSORED ADR 04016X101 58 197 SH DFND 1 197 0 0 ARGENX SE SPONSORED ADR 04016X101 1410 4760 SH DFND 2 4760 0 0 ARISTA NETWORKS INC COM 040413106 5589 19170 SH DFND 1 19170 0 0 ARISTA NETWORKS INC COM 040413106 1 5 SH SOLE 5 0 0 ARMSTRONG WORLD INDS INC COM 04247X102 1316 17836 SH DFND 1 17836 0 0 ARRAY TECHNOLOGIES INC COM SHS 04271T100 6366 150000 SH DFND 1 150000 0 0 ARRAY TECHNOLOGIES INC COM SHS 04271T100 492 11600 SH DFND 2 11600 0 0 ARROW ELECTRS INC COM 042735100 1671 17308 SH DFND 1 17308 0 0 ARROW ELECTRS INC COM 042735100 975 10100 SH DFND 2 10100 0 0 ARROW ELECTRS INC COM 042735100 1 10 SH SOLE 10 0 0 ARROWHEAD PHARMACEUTICALS IN COM 04280A100 2865 36850 SH DFND 2 36850 0 0 ARVINAS INC COM 04335A105 1567 19450 SH DFND 2 19450 0 0 ASCENDIS PHARMA A/ S SPONSORED ADR 04351P101 1885 11270 SH DFND 2 11270 0 0 ASSURANT INC COM 04621X108 625 4703 SH DFND 1 4703 0 0 ASSURANT INC COM 04621X108 1 4 SH SOLE 4 0 0 ASTRAZENECA PLC SPONSORED ADR 046353108 4035 80000 SH DFND 2 80000 0 0 AT& T INC COM 00206R102 104686 3657076 SH DFND 1 3657076 0 0 AT& T INC COM 00206R102 18332 640405 SH DFND 2 640405 0 0 AT& T INC COM 00206R102 16 573 SH SOLE 573 0 0 ATARA BIOTHERAPEUTICS INC COM 046513107 575 27600 SH DFND 2 27600 0 0 ATHENE HOLDING LTD CL A G0684D107 338 8427 SH DFND 1 8427 0 0 ATHENEX INC COM 04685N103 349 31900 SH DFND 2 31900 0 0 ATLASSIAN CORP PLC CL A G06242104 1196 5090 SH DFND 1 5090 0 0 ATMOS ENERGY CORP COM 049560105 9576 103102 SH DFND 1 103102 0 0 ATMOS ENERGY CORP COM 049560105 16262 175093 SH DFND 2 175093 0 0 ATMOS ENERGY CORP COM 049560105 0 1 SH SOLE 1 0 0 AURINIA PHARMACEUTICALS INC COM 05156V102 623 45600 SH DFND 2 45600 0 0 AUTODESK INC COM 052769106 22873 76455 SH DFND 1 76455 0 0 AUTODESK INC COM 052769106 8251 27580 SH DFND 2 27580 0 0 AUTODESK INC COM 052769106 5 17 SH SOLE 17 0 0 AUTOHOME INC SP ADR RP CL A 05278C107 463 4790 SH DFND 1 4790 0 0 AUTOLIV INC COM 052800109 503 5449 SH DFND 1 5449 0 0 AUTOLIV INC COM 052800109 0 5 SH SOLE 5 0 0 AUTOMATIC DATA PROCESSING IN COM 053015103 26795 153288 SH DFND 1 153288 0 0 AUTOMATIC DATA PROCESSING IN COM 053015103 20252 115858 SH DFND 2 115858 0 0 AUTOMATIC DATA PROCESSING IN COM 053015103 6 33 SH SOLE 33 0 0 AUTONATION INC COM 05329W102 344 5000 SH DFND 1 5000 0 0 AUTONATION INC COM 05329W102 792 11500 SH DFND 2 11500 0 0 AUTOZONE INC COM 053332102 5161 4322 SH DFND 1 4322 0 0 AUTOZONE INC COM 053332102 10175 8520 SH DFND 2 8520 0 0 AUTOZONE INC COM 053332102 2 2 SH SOLE 2 0 0 AVADEL PHARMACEUTICALS PLC SPONSORED ADR 05337M104 123 20000 SH DFND 2 20000 0 0 AVALARA INC COM 05338G106 2838 16555 SH DFND 1 16555 0 0 AVALONBAY CMNTYS INC COM 053484101 5196 33522 SH DFND 1 33522 0 0 AVALONBAY CMNTYS INC COM 053484101 2 10 SH SOLE 10 0 0 AVANGRID INC COM 05351W103 1316 29550 SH DFND 1 29550 0 0 AVANTOR INC COM 05352A100 933 35129 SH DFND 1 35129 0 0 AVERY DENNISON CORP COM 053611109 15939 104492 SH DFND 1 104492 0 0 AVERY DENNISON CORP COM 053611109 2364 15500 SH DFND 2 15500 0 0 AVERY DENNISON CORP COM 053611109 1 5 SH SOLE 5 0 0 AVIDITY BIOSCIENCES INC COM 05370A108 384 14000 SH DFND 2 14000 0 0 AVNET INC COM 053807103 356 10200 SH DFND 1 10200 0 0 AVNET INC COM 053807103 818 23400 SH DFND 2 23400 0 0 AVROBIO INC COM 05455M100 228 16000 SH DFND 2 16000 0 0 AXALTA COATING SYS LTD COM G0750C108 8559 305155 SH DFND 1 305155 0 0 AXON ENTERPRISE INC COM 05464C101 215 1733 SH DFND 1 1733 0 0 AXSOME THERAPEUTICS INC COM 05464T104 1029 12650 SH DFND 2 12650 0 0 B2GOLD CORP COM 11777Q209 3786 676283 SH DFND 1 676283 0 0 B2GOLD CORP COM 11777Q209 503 89800 SH DFND 2 89800 0 0 BAIDU INC SPON ADR REP A 056752108 28677 144973 SH DFND 1 144973 0 0 BAIDU INC SPON ADR REP A 056752108 375 1895 SH DFND 2 1895 0 0 BAKER HUGHES COMPANY CL A 05722G100 2518 122009 SH DFND 1 122009 0 0 BAKER HUGHES COMPANY CL A 05722G100 0 7 SH SOLE 7 0 0 BALL CORP COM 058498106 7264 78695 SH DFND 1 78695 0 0 BALL CORP COM 058498106 2423 26250 SH DFND 2 26250 0 0 BALL CORP COM 058498106 1 16 SH SOLE 16 0 0 BALLARD PWR SYS INC NEW COM 058586108 472 21200 SH DFND 2 21200 0 0 BANCO BRADESCO S A SP ADR PFD NEW 059460303 169 32235 SH DFND 1 32235 0 0 BANCO BRADESCO S A SP ADR PFD NEW 059460303 231 44000 SH DFND 2 44000 0 0 BANCO DE CHILE SPONSORED ADS 059520106 239 11925 SH DFND 2 11925 0 0 BANCO SANTANDER CHILE NEW SP ADR REP COM 05965X109 234 12100 SH DFND 2 12100 0 0 BANK MONTREAL QUE COM 063671101 6044 79894 SH DFND 1 79894 0 0 BANK NEW YORK MELLON CORP COM 064058100 12744 308142 SH DFND 1 308142 0 0 BANK NEW YORK MELLON CORP COM 064058100 3 64 SH SOLE 64 0 0 BANK NOVA SCOTIA B C COM 064149107 15895 292375 SH DFND 1 292375 0 0 BANK OZK COM 06417N103 396 12870 SH DFND 1 12870 0 0 BANK OZK COM 06417N103 904 29400 SH DFND 2 29400 0 0 BAOZUN INC SPONSORED ADR 06684L103 91 2701 SH DFND 1 2701 0 0 BARRICK GOLD CORP COM 067901108 67969 2952139 SH DFND 1 2952139 0 0 BARRICK GOLD CORP COM 067901108 9206 399854 SH DFND 2 399854 0 0 BAUSCH HEALTH COS INC COM 071734107 215 10884 SH DFND 1 10884 0 0 BAUSCH HEALTH COS INC COM 071734107 0 19 SH SOLE 19 0 0 BAXTER INTL INC COM 071813109 17420 217164 SH DFND 1 217164 0 0 BAXTER INTL INC COM 071813109 21834 272177 SH DFND 2 272177 0 0 BAXTER INTL INC COM 071813109 3 41 SH SOLE 41 0 0 BCE INC COM NEW 05534B760 59071 1392873 SH DFND 1 1392873 0 0 BCE INC COM NEW 05534B760 29985 707037 SH DFND 2 707037 0 0 BEAM THERAPEUTICS INC COM 07373V105 1773 20000 SH DFND 2 20000 0 0 BECTON DICKINSON & CO COM 075887109 26100 103093 SH DFND 1 103093 0 0 BECTON DICKINSON & CO COM 075887109 24139 95350 SH DFND 2 95350 0 0 BEIGENE LTD SPONSORED ADR 07725L102 3503 14098 SH DFND 1 14098 0 0 BEIGENE LTD SPONSORED ADR 07725L102 3242 13045 SH DFND 2 13045 0 0 BEIGENE LTD SPONSORED ADR 07725L102 14 56 SH SOLE 56 0 0 BENTLEY SYS INC COM CL B 08265T208 4767 125000 SH DFND 1 125000 0 0 BENTLEY SYS INC COM CL B 08265T208 8962 235000 SH DFND 2 235000 0 0 BERKLEY W R CORP COM 084423102 913 13880 SH DFND 1 13880 0 0 BERKLEY W R CORP COM 084423102 1 17 SH SOLE 17 0 0 BERKSHIRE HATHAWAY INC DEL CL A 084670108 685 2 SH DFND 1 2 0 0 BERKSHIRE HATHAWAY INC DEL CL A 084670108 2398 7 SH DFND 2 7 0 0 BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 65777 285389 SH DFND 1 285389 0 0 BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 31272 135682 SH DFND 2 135682 0 0 BERRY GLOBAL GROUP INC COM 08579W103 827 15068 SH DFND 1 15068 0 0 BERRY GLOBAL GROUP INC COM 08579W103 813 14812 SH DFND 2 14812 0 0 BEST BUY INC COM 086516101 8626 85741 SH DFND 1 85741 0 0 BEST BUY INC COM 086516101 745 7408 SH DFND 2 7408 0 0 BEST BUY INC COM 086516101 2 17 SH SOLE 17 0 0 BEYOND MEAT INC COM 08862E109 7678 60000 SH DFND 1 60000 0 0 BHP GROUP LTD SPONSORED ADS 088606108 163 2470 SH DFND 2 2470 0 0 BILIBILI INC SPONS ADS REP Z 090040106 2230 25531 SH DFND 1 25531 0 0 BILIBILI INC SPONS ADS REP Z 090040106 131 1500 SH DFND 2 1500 0 0 BIO RAD LABS INC CL A 090572207 5071 8846 SH DFND 1 8846 0 0 BIO RAD LABS INC CL A 090572207 1 2 SH SOLE 2 0 0 BIO- TECHNE CORP COM 09073M104 1640 5250 SH DFND 1 5250 0 0 BIOCRYST PHARMACEUTICALS INC COM 09058V103 734 105265 SH DFND 2 105265 0 0 BIOGEN INC COM 09062X103 18590 75995 SH DFND 1 75995 0 0 BIOGEN INC COM 09062X103 33837 138322 SH DFND 2 138322 0 0 BIOGEN INC COM 09062X103 8 34 SH SOLE 34 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 13941 161591 SH DFND 1 161591 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 8109 94000 SH DFND 2 94000 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 1 10 SH SOLE 10 0 0 BIONTECH SE SPONSORED ADS 09075V102 9815 109903 SH DFND 1 109903 0 0 BIONTECH SE SPONSORED ADS 09075V102 2175 24350 SH DFND 2 24350 0 0 BJS WHSL CLUB HLDGS INC COM 05550J101 496 13188 SH DFND 1 13188 0 0 BK OF AMERICA CORP COM 060505104 50016 1658840 SH DFND 1 1658840 0 0 BK OF AMERICA CORP COM 060505104 11775 390533 SH DFND 2 390533 0 0 BK OF AMERICA CORP COM 060505104 20 657 SH SOLE 657 0 0 BLACK DIAMOND THERAPEUTICS I COM 09203E105 409 12400 SH DFND 2 12400 0 0 BLACK KNIGHT INC COM 09215C105 1096 12465 SH DFND 1 12465 0 0 BLACKBAUD INC COM 09227Q100 246 4325 SH DFND 2 4325 0 0 BLACKBERRY LTD COM 09228F103 122 18086 SH DFND 1 18086 0 0 BLACKROCK INC COM 09247X101 47399 66433 SH DFND 1 66433 0 0 BLACKROCK INC COM 09247X101 9749 13664 SH DFND 2 13664 0 0 BLACKROCK INC COM 09247X101 9 12 SH SOLE 12 0 0 BLACKSTONE GROUP INC COM CL A 09260D107 6067 93767 SH DFND 1 93767 0 0 BLACKSTONE GROUP INC COM CL A 09260D107 3 53 SH SOLE 53 0 0 BLOCK H & R INC COM 093671105 611 39136 SH DFND 1 39136 0 0 BLOCK H & R INC COM 093671105 847 54195 SH DFND 2 54195 0 0 BLUEBIRD BIO INC COM 09609G100 1174 26730 SH DFND 2 26730 0 0 BLUEPRINT MEDICINES CORP COM 09627Y109 2558 22250 SH DFND 2 22250 0 0 BOEING CO COM 097023105 16747 77026 SH DFND 1 77026 0 0 BOEING CO COM 097023105 9218 42400 SH DFND 2 42400 0 0 BOOKING HOLDINGS INC COM 09857L108 40213 18429 SH DFND 1 18429 0 0 BOOKING HOLDINGS INC COM 09857L108 6328 2900 SH DFND 2 2900 0 0 BOOKING HOLDINGS INC COM 09857L108 7 3 SH SOLE 3 0 0 BOOZ ALLEN HAMILTON HLDG COR CL A 099502106 1520 17407 SH DFND 1 17407 0 0 BOOZ ALLEN HAMILTON HLDG COR CL A 099502106 7045 80664 SH DFND 2 80664 0 0 BOOZ ALLEN HAMILTON HLDG COR CL A 099502106 1 14 SH SOLE 14 0 0 BORGWARNER INC COM 099724106 1269 33062 SH DFND 1 33062 0 0 BORGWARNER INC COM 099724106 1115 29053 SH DFND 2 29053 0 0 BOSTON BEER INC CL A 100557107 1182 1209 SH DFND 1 1209 0 0 BOSTON PROPERTIES INC COM 101121101 1631 17673 SH DFND 1 17673 0 0 BOSTON PROPERTIES INC COM 101121101 1 6 SH SOLE 6 0 0 BOSTON SCIENTIFIC CORP COM 101137107 10477 290674 SH DFND 1 290674 0 0 BOSTON SCIENTIFIC CORP COM 101137107 9043 250900 SH DFND 2 250900 0 0 BOSTON SCIENTIFIC CORP COM 101137107 2 51 SH SOLE 51 0 0 BRADY CORP CL A 104674106 1074 20887 SH DFND 1 20887 0 0 BRADY CORP CL A 104674106 1717 33399 SH DFND 2 33399 0 0 BRF SA SPONSORED ADR 10552T107 42 10000 SH DFND 1 10000 0 0 BRIDGEBIO PHARMA INC COM 10806X102 2545 38200 SH DFND 2 38200 0 0 BRIGHT HORIZONS FAM SOL IN D COM 109194100 2649 15380 SH DFND 1 15380 0 0 BRIGHT HORIZONS FAM SOL IN D COM 109194100 2239 13000 SH DFND 2 13000 0 0 BRIGHTHOUSE FINL INC COM 10922N103 342 9800 SH DFND 1 9800 0 0 BRIGHTHOUSE FINL INC COM 10922N103 790 22600 SH DFND 2 22600 0 0 BRISTOL- MYERS SQUIBB CO COM 110122108 110850 1790042 SH DFND 1 1790042 0 0 BRISTOL- MYERS SQUIBB CO COM 110122108 45573 735926 SH DFND 2 735926 0 0 BRISTOL- MYERS SQUIBB CO COM 110122108 10 156 SH SOLE 156 0 0 BRISTOL- MYERS SQUIBB CO RIGHT 99/ 99/ 9999 110122157 149 93420 SH DFND 1 93420 0 0 BRISTOL- MYERS SQUIBB CO RIGHT 99/ 99/ 9999 110122157 152 95000 SH DFND 2 95000 0 0 BRIXMOR PPTY GROUP INC COM 11120U105 123 7703 SH DFND 1 7703 0 0 BROADCOM INC COM 11135F101 213775 499583 SH DFND 1 499583 0 0 BROADCOM INC COM 11135F101 68936 161100 SH DFND 2 161100 0 0 BROADCOM INC COM 11135F101 10 24 SH SOLE 24 0 0 BROADRIDGE FINL SOLUTIONS IN COM 11133T103 4555 30107 SH DFND 1 30107 0 0 BROADRIDGE FINL SOLUTIONS IN COM 11133T103 1 8 SH SOLE 8 0 0 BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 78526 1914947 SH DFND 1 1914947 0 0 BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 6980 170225 SH DFND 2 170225 0 0 BROOKFIELD RENEWABLE CORP CL A SUB VTG 11284V105 621 10548 SH DFND 1 10548 0 0 BROWN & BROWN INC COM 115236101 5648 123412 SH DFND 1 123412 0 0 BROWN & BROWN INC COM 115236101 5941 129829 SH DFND 2 129829 0 0 BROWN & BROWN INC COM 115236101 1 16 SH SOLE 16 0 0 BROWN FORMAN CORP CL A 115637100 33 454 SH DFND 1 454 0 0 BROWN FORMAN CORP CL B 115637209 7158 91001 SH DFND 1 91001 0 0 BROWN FORMAN CORP CL B 115637209 2 20 SH SOLE 20 0 0 BRUNSWICK CORP COM 117043109 856 10957 SH DFND 1 10957 0 0 BUILDERS FIRSTSOURCE INC COM 12008R107 327 7815 SH DFND 1 7815 0 0 BUNGE LIMITED COM G16962105 788 12407 SH DFND 1 12407 0 0 BUNGE LIMITED COM G16962105 3 53 SH SOLE 53 0 0 BURLINGTON STORES INC COM 122017106 1941 7514 SH DFND 1 7514 0 0 BURLINGTON STORES INC COM 122017106 1 5 SH SOLE 5 0 0 BWX TECHNOLOGIES INC COM 05605H100 686 11515 SH DFND 1 11515 0 0 C H ROBINSON WORLDWIDE INC COM NEW 12541W209 7106 76505 SH DFND 1 76505 0 0 C H ROBINSON WORLDWIDE INC COM NEW 12541W209 12939 139319 SH DFND 2 139319 0 0 C H ROBINSON WORLDWIDE INC COM NEW 12541W209 1 9 SH SOLE 9 0 0 C3 AI INC CL A 12468P104 538 3800 SH DFND 1 3800 0 0 CABLE ONE INC COM 12685J105 2377 1050 SH DFND 1 1050 0 0 CABOT OIL & GAS CORP COM 127097103 924 59156 SH DFND 1 59156 0 0 CACI INTL INC CL A 127190304 352 1416 SH DFND 1 1416 0 0 CACI INTL INC CL A 127190304 721 2900 SH DFND 2 2900 0 0 CADENCE DESIGN SYSTEM INC COM 127387108 16715 124913 SH DFND 1 124913 0 0 CADENCE DESIGN SYSTEM INC COM 127387108 1154 8622 SH DFND 2 8622 0 0 CADENCE DESIGN SYSTEM INC COM 127387108 3 22 SH SOLE 22 0 0 CADENCE DESIGN SYSTEM INC COM 127387108 0 4800 SH Put DFND 1 4800 0 0 CAE INC COM 124765108 234 8583 SH DFND 1 8583 0 0 CAESARS ENTERTAINMENT INC NE COM 12769G100 845 11644 SH DFND 1 11644 0 0 CAESARSTONE LTD ORD SHS M20598104 385 29838 SH DFND 1 29838 0 0 CALIFORNIA WTR SVC GROUP COM 130788102 267 5000 SH DFND 2 5000 0 0 CALLAWAY GOLF CO COM 131193104 73 3000 SH DFND 1 3000 0 0 CAMDEN PPTY TR SH BEN INT 133131102 741 7580 SH DFND 1 7580 0 0 CAMDEN PPTY TR SH BEN INT 133131102 1 6 SH SOLE 6 0 0 CAMECO CORP COM 13321L108 1133 83352 SH DFND 1 83352 0 0 CAMPBELL SOUP CO COM 134429109 20482 425226 SH DFND 1 425226 0 0 CAMPBELL SOUP CO COM 134429109 35111 728952 SH DFND 2 728952 0 0 CAMPBELL SOUP CO COM 134429109 1 12 SH SOLE 12 0 0 CANADA GOOSE HLDGS INC SHS SUB VTG 135086106 2461 83197 SH DFND 1 83197 0 0 CANADIAN IMP BK COMM COM 136069101 3183 37379 SH DFND 1 37379 0 0 CANADIAN IMP BK COMM COM 136069101 568 6666 SH DFND 2 6666 0 0 CANADIAN NAT RES LTD COM 136385101 3557 149814 SH DFND 1 149814 0 0 CANADIAN NAT RES LTD COM 136385101 2499 105241 SH DFND 2 105241 0 0 CANADIAN NATL RY CO COM 136375102 8568 77720 SH DFND 1 77720 0 0 CANADIAN NATL RY CO COM 136375102 5555 50390 SH DFND 2 50390 0 0 CANADIAN PAC RY LTD COM 13645T100 25533 73474 SH DFND 1 73474 0 0 CANADIAN PAC RY LTD COM 13645T100 3718 10700 SH DFND 2 10700 0 0 CANADIAN SOLAR INC COM 136635109 7198 141000 SH DFND 1 141000 0 0 CANOPY GROWTH CORP COM 138035100 307 12550 SH DFND 1 12550 0 0 CANOPY GROWTH CORP COM 138035100 1 22 SH SOLE 22 0 0 CAPITAL ONE FINL CORP COM 14040H105 6788 70749 SH DFND 1 70749 0 0 CAPITAL ONE FINL CORP COM 14040H105 3 35 SH SOLE 35 0 0 CARA THERAPEUTICS INC COM 140755109 244 16200 SH DFND 2 16200 0 0 CARDINAL HEALTH INC COM 14149Y108 9179 172489 SH DFND 1 172489 0 0 CARDINAL HEALTH INC COM 14149Y108 5256 98770 SH DFND 2 98770 0 0 CARDINAL HEALTH INC COM 14149Y108 1 20 SH SOLE 20 0 0 CARETRUST REIT INC COM 14174T107 1286 58389 SH DFND 1 58389 0 0 CARLISLE COS INC COM 142339100 728 4697 SH DFND 1 4697 0 0 CARLISLE COS INC COM 142339100 3540 22842 SH DFND 2 22842 0 0 CARLYLE GROUP INC COM 14316J108 273 8883 SH DFND 1 8883 0 0 CARLYLE GROUP INC COM 14316J108 0 10 SH SOLE 10 0 0 CARMAX INC COM 143130102 1562 17045 SH DFND 1 17045 0 0 CARMAX INC COM 143130102 1 7 SH SOLE 7 0 0 CARNIVAL CORP UNIT 99/ 99/ 9999 143658300 1015 46940 SH DFND 1 46940 0 0 CARNIVAL CORP UNIT 99/ 99/ 9999 143658300 205 9500 SH DFND 2 9500 0 0 CARRIER GLOBAL CORPORATION COM 14448C104 12044 322074 SH DFND 1 322074 0 0 CARRIER GLOBAL CORPORATION COM 14448C104 26249 701900 SH DFND 2 701900 0 0 CARRIER GLOBAL CORPORATION COM 14448C104 2 52 SH SOLE 52 0 0 CARVANA CO CL A 146869102 1382 5443 SH DFND 1 5443 0 0 CASEYS GEN STORES INC COM 147528103 173 969 SH DFND 1 969 0 0 CASEYS GEN STORES INC COM 147528103 416 2335 SH DFND 2 2335 0 0 CASTLE BIOSCIENCES INC COM 14843C105 468 7000 SH DFND 2 7000 0 0 CATALENT INC COM 148806102 1151 11201 SH DFND 1 11201 0 0 CATALENT INC COM 148806102 1849 18000 SH DFND 2 18000 0 0 CATERPILLAR INC COM 149123101 29203 162980 SH DFND 1 162980 0 0 CATERPILLAR INC COM 149123101 3027 16894 SH DFND 2 16894 0 0 CATERPILLAR INC COM 149123101 3 18 SH SOLE 18 0 0 CBOE GLOBAL MKTS INC COM 12503M108 3415 37288 SH DFND 1 37288 0 0 CBOE GLOBAL MKTS INC COM 12503M108 4382 47853 SH DFND 2 47853 0 0 CBOE GLOBAL MKTS INC COM 12503M108 1 11 SH SOLE 11 0 0 CBRE GROUP INC CL A 12504L109 18603 299454 SH DFND 1 299454 0 0 CBRE GROUP INC CL A 12504L109 4213 67818 SH DFND 2 67818 0 0 CBRE GROUP INC CL A 12504L109 1 24 SH SOLE 24 0 0 CDK GLOBAL INC COM 12508E101 317 6200 SH DFND 1 6200 0 0 CDK GLOBAL INC COM 12508E101 732 14300 SH DFND 2 14300 0 0 CDK GLOBAL INC COM 12508E101 9 178 SH SOLE 178 0 0 CDW CORP COM 12514G108 3758 29091 SH DFND 1 29091 0 0 CDW CORP COM 12514G108 2132 16505 SH DFND 2 16505 0 0 CDW CORP COM 12514G108 1 11 SH SOLE 11 0 0 CELANESE CORP DEL COM 150870103 1286 10148 SH DFND 1 10148 0 0 CELLECTIS S A SPON ADS 15117K103 203 7000 SH DFND 2 7000 0 0 CENOVUS ENERGY INC COM 15135U109 239 39877 SH DFND 1 39877 0 0 CENTENE CORP DEL COM 15135B101 7760 131575 SH DFND 1 131575 0 0 CENTENE CORP DEL COM 15135B101 7396 125400 SH DFND 2 125400 0 0 CENTENE CORP DEL COM 15135B101 3 53 SH SOLE 53 0 0 CENTERPOINT ENERGY INC COM 15189T107 1719 80778 SH DFND 1 80778 0 0 CERIDIAN HCM HLDG INC COM 15677J108 1494 14036 SH DFND 1 14036 0 0 CERNER CORP COM 156782104 18748 238807 SH DFND 1 238807 0 0 CERNER CORP COM 156782104 17220 219343 SH DFND 2 219343 0 0 CERNER CORP COM 156782104 2 31 SH SOLE 31 0 0 CERTARA INC COM 15687V109 1017 30000 SH DFND 1 30000 0 0 CF INDS HLDGS INC COM 125269100 556 15138 SH DFND 1 15138 0 0 CF INDS HLDGS INC COM 125269100 0 4 SH SOLE 4 0 0 CGI INC CL A SUB VTG 12532H104 11539 144048 SH DFND 1 144048 0 0 CGI INC CL A SUB VTG 12532H104 21301 265900 SH DFND 2 265900 0 0 CHANNELADVISOR CORP COM 159179100 1599 100000 SH DFND 2 100000 0 0 CHARLES RIV LABS INTL INC COM 159864107 373 1500 SH DFND 1 1500 0 0 CHART INDS INC COM PAR $ 0.01 16115Q308 2860 25000 SH DFND 1 25000 0 0 CHARTER COMMUNICATIONS INC N CL A 16119P108 46286 69396 SH DFND 1 69396 0 0 CHARTER COMMUNICATIONS INC N CL A 16119P108 8671 13000 SH DFND 2 13000 0 0 CHARTER COMMUNICATIONS INC N CL A 16119P108 11 16 SH SOLE 16 0 0 CHECK POINT SOFTWARE TECH LT ORD M22465104 16777 124890 SH DFND 1 124890 0 0 CHECK POINT SOFTWARE TECH LT ORD M22465104 46505 346197 SH DFND 2 346197 0 0 CHEGG INC COM 163092109 522 5900 SH DFND 2 5900 0 0 CHEMED CORP NEW COM 16359R103 552 1053 SH DFND 1 1053 0 0 CHEMED CORP NEW COM 16359R103 11411 21775 SH DFND 2 21775 0 0 CHEMOCENTRYX INC COM 16383L106 1640 27100 SH DFND 2 27100 0 0 CHENIERE ENERGY INC COM NEW 16411R208 2308 38467 SH DFND 1 38467 0 0 CHENIERE ENERGY INC COM NEW 16411R208 150 2500 SH DFND 2 2500 0 0 CHENIERE ENERGY INC COM NEW 16411R208 0 3 SH SOLE 3 0 0 CHEVRON CORP NEW COM 166764100 76896 894907 SH DFND 1 894907 0 0 CHEVRON CORP NEW COM 166764100 10651 123950 SH DFND 2 123950 0 0 CHEWY INC CL A 16679L109 623 6454 SH DFND 1 6454 0 0 CHEWY INC CL A 16679L109 2299 23800 SH DFND 2 23800 0 0 CHIMERA INVT CORP COM NEW 16934Q208 64 6274 SH DFND 1 6274 0 0 CHINA BIOLOGIC PRODS HLDGS I COM G21515104 1475 12690 SH DFND 2 12690 0 0 CHINOOK THERAPEUTICS INC COM 16961L106 159 10000 SH DFND 2 10000 0 0 CHIPOTLE MEXICAN GRILL INC COM 169656105 4317 3102 SH DFND 1 3102 0 0 CHIPOTLE MEXICAN GRILL INC COM 169656105 1 1 SH SOLE 1 0 0 CHUBB LIMITED COM H1467J104 12227 79009 SH DFND 1 79009 0 0 CHUBB LIMITED COM H1467J104 5 34 SH SOLE 34 0 0 CHURCH & DWIGHT INC COM 171340102 5034 56831 SH DFND 1 56831 0 0 CHURCH & DWIGHT INC COM 171340102 1981 22367 SH DFND 2 22367 0 0 CHURCH & DWIGHT INC COM 171340102 1 12 SH SOLE 12 0 0 CI FINL CORP COM 125491100 323 25763 SH DFND 1 25763 0 0 CI FINL CORP COM 125491100 5271 420092 SH DFND 2 420092 0 0 CIENA CORP COM NEW 171779309 2464 47518 SH DFND 1 47518 0 0 CIENA CORP COM NEW 171779309 9258 178499 SH DFND 2 178499 0 0 CIGNA CORP NEW COM 125523100 14453 71204 SH DFND 1 71204 0 0 CIGNA CORP NEW COM 125523100 5310 26159 SH DFND 2 26159 0 0 CIGNA CORP NEW COM 125523100 7 35 SH SOLE 35 0 0 CIIG MERGER CORP COM CL A 12559C103 2030 70000 SH DFND 1 70000 0 0 CINCINNATI FINL CORP COM 172062101 1151 13363 SH DFND 1 13363 0 0 CINCINNATI FINL CORP COM 172062101 1 14 SH SOLE 14 0 0 CINTAS CORP COM 172908105 5346 15368 SH DFND 1 15368 0 0 CINTAS CORP COM 172908105 288 829 SH DFND 2 829 0 0 CINTAS CORP COM 172908105 2 7 SH SOLE 7 0 0 CIRRUS LOGIC INC COM 172755100 122 1528 SH DFND 1 1528 0 0 CISCO SYS INC COM 17275R102 206181 4593208 SH DFND 1 4593208 0 0 CISCO SYS INC COM 17275R102 71360 1589724 SH DFND 2 1589724 0 0 CISCO SYS INC COM 17275R102 15 332 SH SOLE 332 0 0 CITIGROUP INC COM NEW 172967424 61224 1001404 SH DFND 1 1001404 0 0 CITIGROUP INC COM NEW 172967424 2926 47864 SH DFND 2 47864 0 0 CITIGROUP INC COM NEW 172967424 12 189 SH SOLE 189 0 0 CITIZENS FINL GROUP INC COM 174610105 7860 224982 SH DFND 1 224982 0 0 CITIZENS FINL GROUP INC COM 174610105 1 32 SH SOLE 32 0 0 CITRIX SYS INC COM 177376100 21657 164997 SH DFND 1 164997 0 0 CITRIX SYS INC COM 177376100 41821 318618 SH DFND 2 318618 0 0 CITRIX SYS INC COM 177376100 7 52 SH SOLE 52 0 0 CLEARWAY ENERGY INC CL C 18539C204 702 22297 SH DFND 1 22297 0 0 CLOROX CO DEL COM 189054109 6264 31029 SH DFND 1 31029 0 0 CLOROX CO DEL COM 189054109 8206 40651 SH DFND 2 40651 0 0 CLOROX CO DEL COM 189054109 1 6 SH SOLE 6 0 0 CLOUDFLARE INC CL A COM 18915M107 721 9234 SH DFND 1 9234 0 0 CLOVIS ONCOLOGY INC COM 189464100 123 28000 SH DFND 2 28000 0 0 CME GROUP INC COM 12572Q105 90040 497044 SH DFND 1 497044 0 0 CME GROUP INC COM 12572Q105 5 25 SH SOLE 25 0 0 CMS ENERGY CORP COM 125896100 67775 1143049 SH DFND 1 1143049 0 0 CMS ENERGY CORP COM 125896100 9591 161760 SH DFND 2 161760 0 0 CMS ENERGY CORP COM 125896100 0 4 SH SOLE 4 0 0 CNH INDL N V SHS N20944109 5378 414370 SH DFND 1 414370 0 0 CNO FINL GROUP INC COM 12621E103 374 16800 SH DFND 1 16800 0 0 CNO FINL GROUP INC COM 12621E103 866 38900 SH DFND 2 38900 0 0 COCA COLA CO COM 191216100 185245 3394656 SH DFND 1 3394656 0 0 COCA COLA CO COM 191216100 39791 729184 SH DFND 2 729184 0 0 COCA COLA CO COM 191216100 14 259 SH SOLE 259 0 0 COCA COLA EUROPEAN PARTNERS SHS G25839104 12855 265570 SH DFND 1 265570 0 0 COCA COLA EUROPEAN PARTNERS SHS G25839104 1157 23900 SH DFND 2 23900 0 0 COCA- COLA FEMSA SAB DE CV SPONSORD ADR REP 191241108 786 17000 SH DFND 1 17000 0 0 COCA- COLA FEMSA SAB DE CV SPONSORD ADR REP 191241108 560 12100 SH DFND 2 12100 0 0 CODEXIS INC COM 192005106 401 18000 SH DFND 2 18000 0 0 COGNEX CORP COM 192422103 2867 36187 SH DFND 1 36187 0 0 COGNEX CORP COM 192422103 41598 525000 SH DFND 2 525000 0 0 COGNEX CORP COM 192422103 1 13 SH SOLE 13 0 0 COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102 13098 161052 SH DFND 1 161052 0 0 COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102 8970 110293 SH DFND 2 110293 0 0 COGNIZANT TECHNOLOGY SOLUTIO CL A 192446102 4 49 SH SOLE 49 0 0 COHERENT INC COM 192479103 34193 230000 SH DFND 2 230000 0 0 COHERUS BIOSCIENCES INC COM 19249H103 645 38100 SH DFND 2 38100 0 0 COLGATE PALMOLIVE CO COM 194162103 25652 300863 SH DFND 1 300863 0 0 COLGATE PALMOLIVE CO COM 194162103 34130 400301 SH DFND 2 400301 0 0 COLGATE PALMOLIVE CO COM 194162103 4 52 SH SOLE 52 0 0 COLLEGIUM PHARMACEUTICAL INC COM 19459J104 205 10400 SH DFND 2 10400 0 0 COMCAST CORP NEW CL A 20030N101 248301 4793300 SH DFND 1 4793300 0 0 COMCAST CORP NEW CL A 20030N101 22793 440012 SH DFND 2 440012 0 0 COMCAST CORP NEW CL A 20030N101 16 304 SH SOLE 304 0 0 COMERICA INC COM 200340107 609 11095 SH DFND 1 11095 0 0 COMERICA INC COM 200340107 872 15900 SH DFND 2 15900 0 0 COMERICA INC COM 200340107 12 213 SH SOLE 213 0 0 COMMERCE BANCSHARES INC COM 200525103 6010 92174 SH DFND 2 92174 0 0 COMMERCIAL METALS CO COM 201723103 636 32499 SH DFND 1 32499 0 0 COMPANHIA DE SANEAMENTO BASI SPONSORED ADR 20441A102 1119 130900 SH DFND 1 130900 0 0 COMPUGEN LTD ORD M25722105 362 30000 SH DFND 2 30000 0 0 CONAGRA BRANDS INC COM 205887102 4675 128597 SH DFND 1 128597 0 0 CONAGRA BRANDS INC COM 205887102 9201 253120 SH DFND 2 253120 0 0 CONAGRA BRANDS INC COM 205887102 1 29 SH SOLE 29 0 0 CONCENTRIX CORP COM 20602D101 210 2100 SH DFND 1 2100 0 0 CONCENTRIX CORP COM 20602D101 490 4900 SH DFND 2 4900 0 0 CONCHO RES INC COM 20605P101 1020 18030 SH DFND 1 18030 0 0 CONOCOPHILLIPS COM 20825C104 71317 1817377 SH DFND 1 1817377 0 0 CONOCOPHILLIPS COM 20825C104 6801 173298 SH DFND 2 173298 0 0 CONSOLIDATED EDISON INC COM 209115104 5926 82637 SH DFND 1 82637 0 0 CONSOLIDATED EDISON INC COM 209115104 323 4498 SH DFND 2 4498 0 0 CONSOLIDATED EDISON INC COM 209115104 1 7 SH SOLE 7 0 0 CONSTELLATION BRANDS INC CL A 21036P108 5421 24864 SH DFND 1 24864 0 0 CONSTELLATION BRANDS INC CL A 21036P108 2 10 SH SOLE 10 0 0 CONSTELLATION PHARMCETICLS I COM 210373106 400 13300 SH DFND 2 13300 0 0 CONTINENTAL RES INC COM 212015101 1104 67500 SH DFND 1 67500 0 0 COOPER COS INC COM NEW 216648402 2736 7670 SH DFND 1 7670 0 0 COOPER COS INC COM NEW 216648402 2241 6282 SH DFND 2 6282 0 0 COPART INC COM 217204106 3721 29652 SH DFND 1 29652 0 0 COPART INC COM 217204106 2 14 SH SOLE 14 0 0 CORESITE RLTY CORP COM 21870Q105 1726 14027 SH DFND 1 14027 0 0 CORNING INC COM 219350105 3574 100609 SH DFND 1 100609 0 0 CORNING INC COM 219350105 10 281 SH SOLE 281 0 0 CORSAIR GAMING INC COM 22041X102 262 7000 SH DFND 1 7000 0 0 CORTEVA INC COM 22052L104 2347 62063 SH DFND 1 62063 0 0 CORTEVA INC COM 22052L104 212 5616 SH DFND 2 5616 0 0 CORTEXYME INC COM 22053A107 283 10000 SH DFND 2 10000 0 0 COSTAR GROUP INC COM 22160N109 6704 7315 SH DFND 1 7315 0 0 COSTCO WHSL CORP NEW COM 22160K105 88854 236472 SH DFND 1 236472 0 0 COSTCO WHSL CORP NEW COM 22160K105 21831 58100 SH DFND 2 58100 0 0 COSTCO WHSL CORP NEW COM 22160K105 11 29 SH SOLE 29 0 0 COUPA SOFTWARE INC COM 22266L106 2797 8312 SH DFND 1 8312 0 0 COUPA SOFTWARE INC COM 22266L106 1 3 SH SOLE 3 0 0 COUSINS PPTYS INC COM NEW 222795502 144 4318 SH DFND 1 4318 0 0 COVANTA HLDG CORP COM 22282E102 2047 160000 SH DFND 2 160000 0 0 CRANE CO COM 224399105 390 5200 SH DFND 1 5200 0 0 CRANE CO COM 224399105 908 12100 SH DFND 2 12100 0 0 CREDICORP LTD COM G2519Y108 3741 23572 SH DFND 2 23572 0 0 CRINETICS PHARMACEUTICALS IN COM 22663K107 129 10000 SH DFND 2 10000 0 0 CRISPR THERAPEUTICS AG NAMEN AKT H17182108 2574 16310 SH DFND 2 16310 0 0 CROCS INC COM 227046109 171 2800 SH DFND 2 2800 0 0 CRONOS GROUP INC COM 22717L101 2 264 SH SOLE 264 0 0 CROWDSTRIKE HLDGS INC CL A 22788C105 3928 18671 SH DFND 1 18671 0 0 CROWDSTRIKE HLDGS INC CL A 22788C105 1052 5000 SH DFND 2 5000 0 0 CROWN CASTLE INTL CORP NEW COM 22822V101 8308 53336 SH DFND 1 53336 0 0 CROWN CASTLE INTL CORP NEW COM 22822V101 2632 16900 SH DFND 2 16900 0 0 CROWN CASTLE INTL CORP NEW COM 22822V101 1 7 SH SOLE 7 0 0 CROWN HLDGS INC COM 228368106 2907 29535 SH DFND 1 29535 0 0 CROWN HLDGS INC COM 228368106 1 7 SH SOLE 7 0 0 CSX CORP COM 126408103 12441 139282 SH DFND 1 139282 0 0 CSX CORP COM 126408103 214 2395 SH DFND 2 2395 0 0 CUBESMART COM 229663109 107 3195 SH DFND 1 3195 0 0 CUBIC CORP COM 229669106 191 3123 SH DFND 1 3123 0 0 CUMMINS INC COM 231021106 7386 32810 SH DFND 1 32810 0 0 CUMMINS INC COM 231021106 23545 104590 SH DFND 2 104590 0 0 CUMMINS INC COM 231021106 3 14 SH SOLE 14 0 0 CUREVAC N V COM N2451R105 4546 50400 SH DFND 1 50400 0 0 CUREVAC N V COM N2451R105 591 6550 SH DFND 2 6550 0 0 CURTISS WRIGHT CORP COM 231561101 58 518 SH DFND 1 518 0 0 CVR ENERGY INC COM 12662P108 314 21300 SH DFND 1 21300 0 0 CVR ENERGY INC COM 12662P108 717 48600 SH DFND 2 48600 0 0 CVS HEALTH CORP COM 126650100 95197 1400154 SH DFND 1 1400154 0 0 CVS HEALTH CORP COM 126650100 11464 168607 SH DFND 2 168607 0 0 CVS HEALTH CORP COM 126650100 6 84 SH SOLE 84 0 0 CYBERARK SOFTWARE LTD SHS M2682V108 1698 10707 SH DFND 1 10707 0 0 CYMABAY THERAPEUTICS INC COM 23257D103 135 24000 SH DFND 2 24000 0 0 CYRUSONE INC COM 23283R100 5162 70521 SH DFND 1 70521 0 0 CYTOKINETICS INC COM NEW 23282W605 505 24600 SH DFND 2 24600 0 0 CYTOMX THERAPEUTICS INC COM 23284F105 70 10100 SH DFND 2 10100 0 0 D R HORTON INC COM 23331A109 4484 63942 SH DFND 1 63942 0 0 D R HORTON INC COM 23331A109 718 10245 SH DFND 2 10245 0 0 D R HORTON INC COM 23331A109 2 27 SH SOLE 27 0 0 DANAHER CORPORATION COM 235851102 66038 295775 SH DFND 1 295775 0 0 DANAHER CORPORATION COM 235851102 34651 155197 SH DFND 2 155197 0 0 DANAHER CORPORATION COM 235851102 6 27 SH SOLE 27 0 0 DAQO NEW ENERGY CORP SPNSRD ADS NEW 23703Q203 238 4245 SH DFND 1 4245 0 0 DARDEN RESTAURANTS INC COM 237194105 1724 14568 SH DFND 1 14568 0 0 DARDEN RESTAURANTS INC COM 237194105 1 7 SH SOLE 7 0 0 DARLING INGREDIENTS INC COM 237266101 57 1000 SH DFND 1 1000 0 0 DARLING INGREDIENTS INC COM 237266101 8845 154300 SH DFND 2 154300 0 0 DATADOG INC CL A COM 23804L103 1310 13390 SH DFND 1 13390 0 0 DAVITA INC COM 23918K108 3299 28472 SH DFND 1 28472 0 0 DAVITA INC COM 23918K108 488 4209 SH DFND 2 4209 0 0 DAVITA INC COM 23918K108 2 18 SH SOLE 18 0 0 DECIPHERA PHARMACEUTICALS IN COM 24344T101 1988 36400 SH DFND 2 36400 0 0 DECKERS OUTDOOR CORP COM 243537107 568 1973 SH DFND 1 1973 0 0 DECKERS OUTDOOR CORP COM 243537107 1770 6150 SH DFND 2 6150 0 0 DEERE & CO COM 244199105 19735 74374 SH DFND 1 74374 0 0 DEERE & CO COM 244199105 11436 43100 SH DFND 2 43100 0 0 DEERE & CO COM 244199105 5 20 SH SOLE 20 0 0 DELL TECHNOLOGIES INC CL C 24703L202 1572 22247 SH DFND 1 22247 0 0 DELL TECHNOLOGIES INC CL C 24703L202 8 109 SH SOLE 109 0 0 DELTA AIR LINES INC DEL COM NEW 247361702 1167 29088 SH DFND 1 29088 0 0 DELTA AIR LINES INC DEL COM NEW 247361702 0 7 SH SOLE 7 0 0 DENALI THERAPEUTICS INC COM 24823R105 3216 37900 SH DFND 2 37900 0 0 DENTSPLY SIRONA INC COM 24906P109 1215 23624 SH DFND 1 23624 0 0 DENTSPLY SIRONA INC COM 24906P109 2216 43100 SH DFND 2 43100 0 0 DENTSPLY SIRONA INC COM 24906P109 1 20 SH SOLE 20 0 0 DEUTSCHE BANK A G NAMEN AKT D18190898 131939 11930399 SH DFND 1 11930399 0 0 DEUTSCHE BANK A G NAMEN AKT D18190898 7686 695000 SH DFND 2 695000 0 0 DEUTSCHE BANK A G NAMEN AKT D18190898 8960 810174 SH SOLE 810174 0 0 DEVON ENERGY CORP NEW COM 25179M103 19 1275 SH DFND 1 1275 0 0 DEXCOM INC COM 252131107 4636 12952 SH DFND 1 12952 0 0 DEXCOM INC COM 252131107 5404 15100 SH DFND 2 15100 0 0 DEXCOM INC COM 252131107 0 1 SH SOLE 1 0 0 DIAMONDBACK ENERGY INC COM 25278X109 25 526 SH DFND 1 526 0 0 DIAMONDBACK ENERGY INC COM 25278X109 176 3694 SH DFND 2 3694 0 0 DICERNA PHARMACEUTICALS INC COM 253031108 1732 78200 SH DFND 2 78200 0 0 DIGITAL RLTY TR INC COM 253868103 6796 49580 SH DFND 1 49580 0 0 DISCOVER FINL SVCS COM 254709108 13766 156511 SH DFND 1 156511 0 0 DISCOVER FINL SVCS COM 254709108 6931 78800 SH DFND 2 78800 0 0 DISCOVER FINL SVCS COM 254709108 2 25 SH SOLE 25 0 0 DISCOVERY INC COM SER A 25470F104 1726 58468 SH DFND 1 58468 0 0 DISCOVERY INC COM SER A 25470F104 800 27100 SH DFND 2 27100 0 0 DISCOVERY INC COM SER A 25470F104 0 9 SH SOLE 9 0 0 DISCOVERY INC COM SER C 25470F302 833 32262 SH DFND 1 32262 0 0 DISCOVERY INC COM SER C 25470F302 1 45 SH SOLE 45 0 0 DISH NETWORK CORPORATION CL A 25470M109 658 20728 SH DFND 1 20728 0 0 DISNEY WALT CO COM 254687106 207538 1160949 SH DFND 1 1160949 0 0 DISNEY WALT CO COM 254687106 28988 162155 SH DFND 2 162155 0 0 DISNEY WALT CO COM 254687106 22 122 SH SOLE 122 0 0 DISNEY WALT CO COM 254687106 0 5000 SH Call DFND 2 5000 0 0 DISNEY WALT CO COM 254687106 0 15000 SH Put DFND 1 15000 0 0 DOCUSIGN INC COM 256163106 13321 57968 SH DFND 1 57968 0 0 DOCUSIGN INC COM 256163106 42213 183700 SH DFND 2 183700 0 0 DOCUSIGN INC COM 256163106 2 7 SH SOLE 7 0 0 DOLBY LABORATORIES INC COM CL A 25659T107 925 9700 SH DFND 2 9700 0 0 DOLLAR GEN CORP NEW COM 256677105 40608 192324 SH DFND 1 192324 0 0 DOLLAR GEN CORP NEW COM 256677105 23690 112197 SH DFND 2 112197 0 0 DOLLAR GEN CORP NEW COM 256677105 5 26 SH SOLE 26 0 0 DOLLAR TREE INC COM 256746108 4653 42798 SH DFND 1 42798 0 0 DOLLAR TREE INC COM 256746108 203 1863 SH DFND 2 1863 0 0 DOLLAR TREE INC COM 256746108 2 16 SH SOLE 16 0 0 DOMINION ENERGY INC COM 25746U109 78011 1049242 SH DFND 1 1049242 0 0 DOMINION ENERGY INC COM 25746U109 4751 63897 SH DFND 2 63897 0 0 DOMINOS PIZZA INC COM 25754A201 3222 8449 SH DFND 1 8449 0 0 DOMINOS PIZZA INC COM 25754A201 187 490 SH DFND 2 490 0 0 DOMINOS PIZZA INC COM 25754A201 0 1 SH SOLE 1 0 0 DONALDSON INC COM 257651109 420 7386 SH DFND 2 7386 0 0 DOUGLAS EMMETT INC COM 25960P109 110 3869 SH DFND 1 3869 0 0 DOUYU INTL HLDGS LTD SPONSORED ADS 25985W105 736 66516 SH DFND 1 66516 0 0 DOVER CORP COM 260003108 3899 31697 SH DFND 1 31697 0 0 DOVER CORP COM 260003108 713 5792 SH DFND 2 5792 0 0 DOVER CORP COM 260003108 1 10 SH SOLE 10 0 0 DOW INC COM 260557103 8494 156458 SH DFND 1 156458 0 0 DOW INC COM 260557103 7590 139820 SH DFND 2 139820 0 0 DRAFTKINGS INC COM CL A 26142R104 755 15666 SH DFND 1 15666 0 0 DROPBOX INC CL A 26210C104 757 32774 SH DFND 1 32774 0 0 DROPBOX INC CL A 26210C104 154 6644 SH DFND 2 6644 0 0 DTE ENERGY CO COM 233331107 5810 48694 SH DFND 1 48694 0 0 DTE ENERGY CO COM 233331107 8157 68361 SH DFND 2 68361 0 0 DUKE ENERGY CORP NEW COM NEW 26441C204 45816 508452 SH DFND 1 508452 0 0 DUKE ENERGY CORP NEW COM NEW 26441C204 5595 62094 SH DFND 2 62094 0 0 DUKE REALTY CORP COM NEW 264411505 7881 200199 SH DFND 1 200199 0 0 DUKE REALTY CORP COM NEW 264411505 257 6541 SH DFND 2 6541 0 0 DUKE REALTY CORP COM NEW 264411505 1 22 SH SOLE 22 0 0 DUN & BRADSTREET HLDGS INC COM 26484T106 905 35000 SH DFND 1 35000 0 0 DUPONT DE NEMOURS INC COM 26614N102 7629 109765 SH DFND 1 109765 0 0 DXC TECHNOLOGY CO COM 23355L106 424 17926 SH DFND 1 17926 0 0 DXC TECHNOLOGY CO COM 23355L106 781 33000 SH DFND 2 33000 0 0 DYNATRACE INC COM NEW 268150109 460 9752 SH DFND 1 9752 0 0 EAGLE PHARMACEUTICALS INC COM 269796108 319 6900 SH DFND 2 6900 0 0 EAST WEST BANCORP INC COM 27579R104 11 219 SH SOLE 219 0 0 EASTERLY GOVT PPTYS INC COM 27616P103 230 10109 SH DFND 1 10109 0 0 EASTGROUP PPTYS INC COM 277276101 2815 20804 SH DFND 1 20804 0 0 EASTMAN CHEM CO COM 277432100 4296 43444 SH DFND 1 43444 0 0 EASTMAN CHEM CO COM 277432100 4846 49000 SH DFND 2 49000 0 0 EATON CORP PLC SHS G29183103 127234 1087933 SH DFND 1 1087933 0 0 EATON CORP PLC SHS G29183103 2478 21191 SH DFND 2 21191 0 0 EATON CORP PLC SHS G29183103 5 46 SH SOLE 46 0 0 EBAY INC. COM 278642103 13963 273183 SH DFND 1 273183 0 0 EBAY INC. COM 278642103 13320 260595 SH DFND 2 260595 0 0 EBAY INC. COM 278642103 10 189 SH SOLE 189 0 0 ECOLAB INC COM 278865100 29992 139304 SH DFND 1 139304 0 0 ECOLAB INC COM 278865100 10327 47965 SH DFND 2 47965 0 0 ECOLAB INC COM 278865100 1 5 SH SOLE 5 0 0 EDISON INTL COM 281020107 3061 50169 SH DFND 1 50169 0 0 EDITAS MEDICINE INC COM 28106W103 1525 19800 SH DFND 2 19800 0 0 EDWARDS LIFESCIENCES CORP COM 28176E108 19347 213981 SH DFND 1 213981 0 0 EDWARDS LIFESCIENCES CORP COM 28176E108 18790 207812 SH DFND 2 207812 0 0 EDWARDS LIFESCIENCES CORP COM 28176E108 5 52 SH SOLE 52 0 0 EIDOS THERAPEUTICS INC COM 28249H104 1715 13800 SH DFND 2 13800 0 0 ELANCO ANIMAL HEALTH INC COM 28414H103 1257 40322 SH DFND 1 40322 0 0 ELANCO ANIMAL HEALTH INC COM 28414H103 374 12000 SH DFND 2 12000 0 0 ELANCO ANIMAL HEALTH INC COM 28414H103 1 25 SH SOLE 25 0 0 ELASTIC N V ORD SHS N14506104 32901 222500 SH DFND 2 222500 0 0 ELECTRONIC ARTS INC COM 285512109 42157 298358 SH DFND 1 298358 0 0 ELECTRONIC ARTS INC COM 285512109 46279 327531 SH DFND 2 327531 0 0 ELECTRONIC ARTS INC COM 285512109 3 21 SH SOLE 21 0 0 EMCOR GROUP INC COM 29084Q100 364 4000 SH DFND 1 4000 0 0 EMCOR GROUP INC COM 29084Q100 847 9300 SH DFND 2 9300 0 0 EMERGENT BIOSOLUTIONS INC COM 29089Q105 103 1100 SH DFND 1 1100 0 0 EMERSON ELEC CO COM 291011104 70225 886706 SH DFND 1 886706 0 0 EMERSON ELEC CO COM 291011104 5029 63500 SH DFND 2 63500 0 0 EMERSON ELEC CO COM 291011104 5 62 SH SOLE 62 0 0 EMPIRE ST RLTY TR INC CL A 292104106 690 74335 SH DFND 1 74335 0 0 ENANTA PHARMACEUTICALS INC COM 29251M106 143 3450 SH DFND 2 3450 0 0 ENBRIDGE INC COM 29250N105 4153 128679 SH DFND 1 128679 0 0 ENBRIDGE INC COM 29250N105 5310 164527 SH DFND 2 164527 0 0 ENCOMPASS HEALTH CORP COM 29261A100 78 950 SH DFND 1 950 0 0 ENDAVA PLC ADS 29260V105 581 7800 SH DFND 1 7800 0 0 ENDO INTL PLC SHS G30401106 493 76600 SH DFND 2 76600 0 0 ENERGY RECOVERY INC COM 29270J100 465 35000 SH DFND 2 35000 0 0 ENPHASE ENERGY INC COM 29355A107 1528 8808 SH DFND 1 8808 0 0 ENTEGRIS INC COM 29362U104 467 5000 SH DFND 1 5000 0 0 ENTERGY CORP NEW COM 29364G103 2414 25003 SH DFND 1 25003 0 0 ENVISTA HOLDINGS CORPORATION COM 29415F104 487 15000 SH DFND 1 15000 0 0 EOG RES INC COM 26875P101 38995 800498 SH DFND 1 800498 0 0 EOG RES INC COM 26875P101 3844 78916 SH DFND 2 78916 0 0 EPAM SYS INC COM 29414B104 2247 6400 SH DFND 1 6400 0 0 EPAM SYS INC COM 29414B104 2421 6895 SH DFND 2 6895 0 0 EPAM SYS INC COM 29414B104 1 3 SH SOLE 3 0 0 EPIZYME INC COM 29428V104 370 32300 SH DFND 2 32300 0 0 EQUIFAX INC COM 294429105 3035 15915 SH DFND 1 15915 0 0 EQUIFAX INC COM 294429105 2 8 SH SOLE 8 0 0 EQUINIX INC COM 29444U700 27345 38313 SH DFND 1 38313 0 0 EQUINIX INC COM 29444U700 4068 5700 SH DFND 2 5700 0 0 EQUINOX GOLD CORP COM 29446Y502 52 5000 SH DFND 1 5000 0 0 EQUITABLE HLDGS INC COM 29452E101 1268 51780 SH DFND 1 51780 0 0 EQUITABLE HLDGS INC COM 29452E101 832 34000 SH DFND 2 34000 0 0 EQUITY COMWLTH COM SH BEN INT 294628102 72 2691 SH DFND 1 2691 0 0 EQUITY LIFESTYLE PPTYS INC COM 29472R108 2028 33111 SH DFND 1 33111 0 0 EQUITY LIFESTYLE PPTYS INC COM 29472R108 1 12 SH SOLE 12 0 0 EQUITY RESIDENTIAL SH BEN INT 29476L107 4435 76391 SH DFND 1 76391 0 0 EQUITY RESIDENTIAL SH BEN INT 29476L107 2 26 SH SOLE 26 0 0 ERIE INDTY CO CL A 29530P102 487 2019 SH DFND 1 2019 0 0 ERIE INDTY CO CL A 29530P102 0 2 SH SOLE 2 0 0 ESPERION THERAPEUTICS INC NE COM 29664W105 269 10000 SH DFND 2 10000 0 0 ESSENTIAL PPTYS RLTY TR INC COM 29670E107 2499 120281 SH DFND 1 120281 0 0 ESSENTIAL UTILS INC COM 29670G102 3896 85607 SH DFND 1 85607 0 0 ESSENTIAL UTILS INC COM 29670G102 282 6201 SH DFND 2 6201 0 0 ESSENTIAL UTILS INC COM 29670G102 10 228 SH SOLE 228 0 0 ESSEX PPTY TR INC COM 297178105 8064 34144 SH DFND 1 34144 0 0 ESSEX PPTY TR INC COM 297178105 0 1 SH SOLE 1 0 0 ETSY INC COM 29786A106 3019 16681 SH DFND 1 16681 0 0 EVERBRIDGE INC COM 29978A104 675 4610 SH DFND 1 4610 0 0 EVEREST RE GROUP LTD COM G3223R108 2103 9192 SH DFND 1 9192 0 0 EVEREST RE GROUP LTD COM G3223R108 1 4 SH SOLE 4 0 0 EVERGY INC COM 30034W106 967 17939 SH DFND 1 17939 0 0 EVERSOURCE ENERGY COM 30040W108 10685 124983 SH DFND 1 124983 0 0 EVERSOURCE ENERGY COM 30040W108 0 2 SH SOLE 2 0 0 EVOQUA WATER TECHNOLOGIES CO COM 30057T105 2608 100000 SH DFND 1 100000 0 0 EVOQUA WATER TECHNOLOGIES CO COM 30057T105 443 17000 SH DFND 2 17000 0 0 EXACT SCIENCES CORP COM 30063P105 1775 13461 SH DFND 1 13461 0 0 EXACT SCIENCES CORP COM 30063P105 2901 22000 SH DFND 2 22000 0 0 EXELIXIS INC COM 30161Q104 1907 95500 SH DFND 2 95500 0 0 EXELON CORP COM 30161N101 7946 189970 SH DFND 1 189970 0 0 EXELON CORP COM 30161N101 8305 198557 SH DFND 2 198557 0 0 EXPEDIA GROUP INC COM NEW 30212P303 2781 21149 SH DFND 1 21149 0 0 EXPEDIA GROUP INC COM NEW 30212P303 1 7 SH SOLE 7 0 0 EXPEDITORS INTL WASH INC COM 302130109 21763 229762 SH DFND 1 229762 0 0 EXPEDITORS INTL WASH INC COM 302130109 34238 361462 SH DFND 2 361462 0 0 EXPEDITORS INTL WASH INC COM 302130109 1 15 SH SOLE 15 0 0 EXTRA SPACE STORAGE INC COM 30225T102 9628 84613 SH DFND 1 84613 0 0 EXTRA SPACE STORAGE INC COM 30225T102 1 10 SH SOLE 10 0 0 EXXON MOBIL CORP COM 30231G102 59009 1419208 SH DFND 1 1419208 0 0 EXXON MOBIL CORP COM 30231G102 511 12300 SH DFND 2 12300 0 0 F5 NETWORKS INC COM 315616102 2823 16050 SH DFND 1 16050 0 0 F5 NETWORKS INC COM 315616102 1 4 SH SOLE 4 0 0 FACEBOOK INC CL A 30303M102 298073 1073101 SH DFND 1 1073101 0 0 FACEBOOK INC CL A 30303M102 51239 184468 SH DFND 2 184468 0 0 FACTSET RESH SYS INC COM 303075105 1353 4135 SH DFND 1 4135 0 0 FACTSET RESH SYS INC COM 303075105 1 3 SH SOLE 3 0 0 FAIR ISAAC CORP COM 303250104 3546 7099 SH DFND 1 7099 0 0 FAIR ISAAC CORP COM 303250104 119 238 SH DFND 2 238 0 0 FAIR ISAAC CORP COM 303250104 1 2 SH SOLE 2 0 0 FARFETCH LTD ORD SH CL A 30744W107 296 4589 SH DFND 1 4589 0 0 FASTENAL CO COM 311900104 6474 130052 SH DFND 1 130052 0 0 FASTENAL CO COM 311900104 7741 155508 SH DFND 2 155508 0 0 FASTENAL CO COM 311900104 2 42 SH SOLE 42 0 0 FASTLY INC CL A 31188V100 2514 28000 SH DFND 1 28000 0 0 FATE THERAPEUTICS INC COM 31189P102 2819 30150 SH DFND 2 30150 0 0 FEDERAL RLTY INVT TR SH BEN INT NEW 313747206 127 1490 SH DFND 1 1490 0 0 FEDERAL RLTY INVT TR SH BEN INT NEW 313747206 9 103 SH SOLE 103 0 0 FEDERATED HERMES INC CL B 314211103 348 12400 SH DFND 1 12400 0 0 FEDERATED HERMES INC CL B 314211103 805 28700 SH DFND 2 28700 0 0 FEDEX CORP COM 31428X106 7298 27802 SH DFND 1 27802 0 0 FEDEX CORP COM 31428X106 6878 26200 SH DFND 2 26200 0 0 FEDEX CORP COM 31428X106 4 16 SH SOLE 16 0 0 FERRARI N V COM N3167Y103 25084 107013 SH DFND 1 107013 0 0 FIAT CHRYSLER AUTOMOBILES N SHS N31738102 7334 406076 SH DFND 1 406076 0 0 FIAT CHRYSLER AUTOMOBILES N SHS N31738102 8970 496670 SH DFND 2 496670 0 0 FIBROGEN INC COM 31572Q808 1019 26950 SH DFND 2 26950 0 0 FIDELITY NATIONAL FINANCIAL FNF GROUP COM 31620R303 2721 70008 SH DFND 1 70008 0 0 FIDELITY NATIONAL FINANCIAL FNF GROUP COM 31620R303 770 19800 SH DFND 2 19800 0 0 FIDELITY NATIONAL FINANCIAL FNF GROUP COM 31620R303 1 18 SH SOLE 18 0 0 FIDELITY NATL INFORMATION SV COM 31620M106 70892 504186 SH DFND 1 504186 0 0 FIDELITY NATL INFORMATION SV COM 31620M106 3417 24300 SH DFND 2 24300 0 0 FIDELITY NATL INFORMATION SV COM 31620M106 5 37 SH SOLE 37 0 0 FIFTH THIRD BANCORP COM 316773100 4743 175266 SH DFND 1 175266 0 0 FIFTH THIRD BANCORP COM 316773100 1 47 SH SOLE 47 0 0 FIREEYE INC COM 31816Q101 445 20150 SH DFND 1 20150 0 0 FIRST AMERN FINL CORP COM 31847R102 316 6239 SH DFND 1 6239 0 0 FIRST INDL RLTY TR INC COM 32054K103 1247 30350 SH DFND 1 30350 0 0 FIRST REP BK SAN FRANCISCO C COM 33616C100 20485 143555 SH DFND 1 143555 0 0 FIRST REP BK SAN FRANCISCO C COM 33616C100 6949 48696 SH DFND 2 48696 0 0 FIRST REP BK SAN FRANCISCO C COM 33616C100 2 13 SH SOLE 13 0 0 FIRSTENERGY CORP COM 337932107 1581 53535 SH DFND 1 53535 0 0 FIRSTENERGY CORP COM 337932107 1 17 SH SOLE 17 0 0 FIRSTSERVICE CORP NEW COM 33767E202 2217 16235 SH DFND 1 16235 0 0 FISERV INC COM 337738108 13383 119986 SH DFND 1 119986 0 0 FISERV INC COM 337738108 4111 36861 SH DFND 2 36861 0 0 FISERV INC COM 337738108 6 54 SH SOLE 54 0 0 FITBIT INC CL A 33812L102 201 30000 SH DFND 1 30000 0 0 FIVE PRIME THERAPEUTICS INC COM 33830X104 232 13000 SH DFND 2 13000 0 0 FIVERR INTL LTD ORD SHS M4R82T106 73 358 SH DFND 1 358 0 0 FLEETCOR TECHNOLOGIES INC COM 339041105 3438 12703 SH DFND 1 12703 0 0 FLEETCOR TECHNOLOGIES INC COM 339041105 2 7 SH SOLE 7 0 0 FLEX LNG LTD SHS G35947202 9 988 SH DFND 1 988 0 0 FLEX LTD ORD Y2573F102 1183 68426 SH DFND 1 68426 0 0 FLEXION THERAPEUTICS INC COM 33938J106 139 12300 SH DFND 2 12300 0 0 FLIR SYS INC COM 302445101 19 437 SH DFND 1 437 0 0 FLOWERS FOODS INC COM 343498101 142 6226 SH DFND 1 6226 0 0 FLOWERS FOODS INC COM 343498101 1460 64164 SH DFND 2 64164 0 0 FLOWSERVE CORP COM 34354P105 493 13640 SH DFND 1 13640 0 0 FMC CORP COM NEW 302491303 1777 15807 SH DFND 1 15807 0 0 FMC CORP COM NEW 302491303 1 7 SH SOLE 7 0 0 FOOT LOCKER INC COM 344849104 313 7800 SH DFND 1 7800 0 0 FOOT LOCKER INC COM 344849104 722 18000 SH DFND 2 18000 0 0 FORD MTR CO DEL COM 345370860 4634 522641 SH DFND 1 522641 0 0 FORD MTR CO DEL COM 345370860 1 86 SH SOLE 86 0 0 FORMA THERAPEUTICS HLDGS INC SHS 34633R104 182 5000 SH DFND 2 5000 0 0 FORTINET INC COM 34959E109 3626 25027 SH DFND 1 25027 0 0 FORTINET INC COM 34959E109 146 1010 SH DFND 2 1010 0 0 FORTINET INC COM 34959E109 3 24 SH SOLE 24 0 0 FORTIS INC COM 349553107 14311 343720 SH DFND 1 343720 0 0 FORTIS INC COM 349553107 8073 193900 SH DFND 2 193900 0 0 FORTIVE CORP COM 34959J108 10515 154456 SH DFND 1 154456 0 0 FORTIVE CORP COM 34959J108 1 20 SH SOLE 20 0 0 FORTUNE BRANDS HOME & SEC IN COM 34964C106 2395 28217 SH DFND 1 28217 0 0 FORTUNE BRANDS HOME & SEC IN COM 34964C106 1 13 SH SOLE 13 0 0 FOX CORP CL A COM 35137L105 880 30308 SH DFND 1 30308 0 0 FOX CORP CL B COM 35137L204 691 24021 SH DFND 1 24021 0 0 FRANCO NEV CORP COM 351858105 3368 26337 SH DFND 1 26337 0 0 FRANCO NEV CORP COM 351858105 2947 23050 SH DFND 2 23050 0 0 FRANKLIN RESOURCES INC COM 354613101 2020 82122 SH DFND 1 82122 0 0 FRANKLIN RESOURCES INC COM 354613101 780 31700 SH DFND 2 31700 0 0 FRANKLIN RESOURCES INC COM 354613101 1 23 SH SOLE 23 0 0 FREEPORT- MCMORAN INC CL B 35671D857 5129 204167 SH DFND 1 204167 0 0 FREEPORT- MCMORAN INC CL B 35671D857 2070 82400 SH DFND 2 82400 0 0 FREQUENCY THERAPEUTICS INC COM 35803L108 354 10000 SH DFND 2 10000 0 0 FRONTDOOR INC COM 35905A109 1315 27000 SH DFND 2 27000 0 0 FRONTLINE LTD SHS NEW G3682E192 178 28339 SH DFND 1 28339 0 0 FTI CONSULTING INC COM 302941109 3973 36287 SH DFND 2 36287 0 0 FUSION PHARMACEUTICALS INC COM 36118A100 155 13000 SH DFND 2 13000 0 0 G1 THERAPEUTICS INC COM 3621LQ109 845 46900 SH DFND 2 46900 0 0 GALAPAGOS NV SPON ADR 36315X101 263 2760 SH DFND 2 2760 0 0 GALLAGHER ARTHUR J & CO COM 363576109 3123 25777 SH DFND 1 25777 0 0 GALLAGHER ARTHUR J & CO COM 363576109 3384 27926 SH DFND 2 27926 0 0 GALLAGHER ARTHUR J & CO COM 363576109 1 9 SH SOLE 9 0 0 GAMING & LEISURE PPTYS INC COM 36467J108 136 3242 SH DFND 1 3242 0 0 GAP INC COM 364760108 14 684 SH DFND 1 684 0 0 GARMIN LTD SHS H2906T109 13791 114878 SH DFND 1 114878 0 0 GARMIN LTD SHS H2906T109 30430 253477 SH DFND 2 253477 0 0 GARMIN LTD SHS H2906T109 1 10 SH SOLE 10 0 0 GARTNER INC COM 366651107 1662 10476 SH DFND 1 10476 0 0 GARTNER INC COM 366651107 195 1226 SH DFND 2 1226 0 0 GARTNER INC COM 366651107 1 6 SH SOLE 6 0 0 GDS HLDGS LTD SPONSORED ADS 36165L108 372 4115 SH DFND 1 4115 0 0 GENERAC HLDGS INC COM 368736104 2044 9233 SH DFND 1 9233 0 0 GENERAC HLDGS INC COM 368736104 116 522 SH DFND 2 522 0 0 GENERAL DYNAMICS CORP COM 369550108 3899 26494 SH DFND 1 26494 0 0 GENERAL ELECTRIC CO COM 369604103 25928 2448009 SH DFND 1 2448009 0 0 GENERAL MLS INC COM 370334104 30900 518449 SH DFND 1 518449 0 0 GENERAL MLS INC COM 370334104 40030 671629 SH DFND 2 671629 0 0 GENERAL MLS INC COM 370334104 2 31 SH SOLE 31 0 0 GENERAL MTRS CO COM 37045V100 7132 170540 SH DFND 1 170540 0 0 GENERAL MTRS CO COM 37045V100 311 7430 SH DFND 2 7430 0 0 GENERATION BIO CO COM 37148K100 563 17100 SH DFND 2 17100 0 0 GENTEX CORP COM 371901109 1979 58996 SH DFND 1 58996 0 0 GENTEX CORP COM 371901109 7977 237789 SH DFND 2 237789 0 0 GENTHERM INC COM 37253A103 252 3942 SH DFND 1 3942 0 0 GENUINE PARTS CO COM 372460105 2125 21564 SH DFND 1 21564 0 0 GENUINE PARTS CO COM 372460105 1 12 SH SOLE 12 0 0 GERDAU SA SPON ADR REP PFD 373737105 1966 416198 SH DFND 2 416198 0 0 GERON CORP COM 374163103 153 100000 SH DFND 2 100000 0 0 GFL ENVIRONMENTAL INC SUB VTG SHS 36168Q104 4103 145004 SH DFND 1 145004 0 0 GILDAN ACTIVEWEAR INC COM 375916103 241 8685 SH DFND 1 8685 0 0 GILEAD SCIENCES INC COM 375558103 39106 686894 SH DFND 1 686894 0 0 GILEAD SCIENCES INC COM 375558103 57182 1004398 SH DFND 2 1004398 0 0 GILEAD SCIENCES INC COM 375558103 6 104 SH SOLE 104 0 0 GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 938 21450 SH DFND 2 21450 0 0 GLOBAL PMTS INC COM 37940X102 7752 37317 SH DFND 1 37317 0 0 GLOBAL PMTS INC COM 37940X102 261 1258 SH DFND 2 1258 0 0 GLOBAL PMTS INC COM 37940X102 4 20 SH SOLE 20 0 0 GLOBANT S A COM L44385109 215 1000 SH DFND 1 1000 0 0 GLOBANT S A COM L44385109 174 810 SH DFND 2 810 0 0 GLOBE LIFE INC COM 37959E102 1098 12063 SH DFND 1 12063 0 0 GLOBE LIFE INC COM 37959E102 1 10 SH SOLE 10 0 0 GLU MOBILE INC COM 379890106 1043 115000 SH DFND 1 115000 0 0 GODADDY INC CL A 380237107 1635 19865 SH DFND 1 19865 0 0 GODADDY INC CL A 380237107 2 22 SH SOLE 22 0 0 GOLD FIELDS LTD SPONSORED ADR 38059T106 865 95000 SH DFND 2 95000 0 0 GOLDEN OCEAN GROUP LTD SHS NEW G39637205 15 3203 SH DFND 1 3203 0 0 GOLDMAN SACHS GROUP INC COM 38141G104 16589 63850 SH DFND 1 63850 0 0 GOLDMAN SACHS GROUP INC COM 38141G104 2297 8843 SH DFND 2 8843 0 0 GOLDMAN SACHS GROUP INC COM 38141G104 7 26 SH SOLE 26 0 0 GOSSAMER BIO INC COM 38341P102 137 14400 SH DFND 2 14400 0 0 GRAFTECH INTL LTD COM 384313508 383 40000 SH DFND 1 40000 0 0 GRAFTECH INTL LTD COM 384313508 890 92900 SH DFND 2 92900 0 0 GRAINGER W W INC COM 384802104 10529 26027 SH DFND 1 26027 0 0 GRAINGER W W INC COM 384802104 14307 35367 SH DFND 2 35367 0 0 GRAINGER W W INC COM 384802104 2 4 SH SOLE 4 0 0 GRAPHIC PACKAGING HLDG CO COM 388689101 3122 185238 SH DFND 1 185238 0 0 GREIF INC CL A 397624107 706 15511 SH DFND 1 15511 0 0 GSX TECHEDU INC SPONSORED ADS 36257Y109 181 3622 SH DFND 1 3622 0 0 GUARDANT HEALTH INC COM 40131M109 1559 13000 SH DFND 1 13000 0 0 GUARDANT HEALTH INC COM 40131M109 3448 28750 SH DFND 2 28750 0 0 GUIDEWIRE SOFTWARE INC COM 40171V100 625 4935 SH DFND 1 4935 0 0 GUIDEWIRE SOFTWARE INC COM 40171V100 1 5 SH SOLE 5 0 0 GW PHARMACEUTICALS PLC ADS 36197T103 1364 11860 SH DFND 2 11860 0 0 HAEMONETICS CORP COM 405024100 233 1992 SH DFND 1 1992 0 0 HALLIBURTON CO COM 406216101 1652 88723 SH DFND 1 88723 0 0 HALLIBURTON CO COM 406216101 0 14 SH SOLE 14 0 0 HALOZYME THERAPEUTICS INC COM 40637H109 1102 26200 SH DFND 2 26200 0 0 HANESBRANDS INC COM 410345102 601 42083 SH DFND 1 42083 0 0 HANESBRANDS INC COM 410345102 200 14042 SH DFND 2 14042 0 0 HANNON ARMSTRONG SUST INFR C COM 41068X100 93 1505 SH DFND 1 1505 0 0 HANOVER INS GROUP INC COM 410867105 1073 9328 SH DFND 1 9328 0 0 HARTFORD FINL SVCS GROUP INC COM 416515104 3292 69329 SH DFND 1 69329 0 0 HARTFORD FINL SVCS GROUP INC COM 416515104 1695 35700 SH DFND 2 35700 0 0 HARTFORD FINL SVCS GROUP INC COM 416515104 1 26 SH SOLE 26 0 0 HASBRO INC COM 418056107 1684 18110 SH DFND 1 18110 0 0 HASBRO INC COM 418056107 1 8 SH SOLE 8 0 0 HCA HEALTHCARE INC COM 40412C101 5245 31988 SH DFND 1 31988 0 0 HCA HEALTHCARE INC COM 40412C101 13578 82815 SH DFND 2 82815 0 0 HD SUPPLY HLDGS INC COM 40416M105 1185 21159 SH DFND 1 21159 0 0 HD SUPPLY HLDGS INC COM 40416M105 122 2177 SH DFND 2 2177 0 0 HDFC BANK LTD SPONSORED ADS 40415F101 811 11460 SH DFND 1 11460 0 0 HDFC BANK LTD SPONSORED ADS 40415F101 5804 82057 SH DFND 2 82057 0 0 HEALTHCARE RLTY TR COM 421946104 118 4038 SH DFND 1 4038 0 0 HEALTHCARE TR AMER INC CL A NEW 42225P501 1982 71294 SH DFND 1 71294 0 0 HEALTHPEAK PROPERTIES INC COM 42250P103 6769 228812 SH DFND 1 228812 0 0 HEALTHPEAK PROPERTIES INC COM 42250P103 376 12700 SH DFND 2 12700 0 0 HEICO CORP NEW CL A 422806208 1780 15314 SH DFND 1 15314 0 0 HEICO CORP NEW CL A 422806208 1 5 SH SOLE 5 0 0 HEICO CORP NEW COM 422806109 1485 11426 SH DFND 1 11426 0 0 HEICO CORP NEW COM 422806109 0 3 SH SOLE 3 0 0 HENRY JACK & ASSOC INC COM 426281101 1261 7966 SH DFND 1 7966 0 0 HENRY JACK & ASSOC INC COM 426281101 1 5 SH SOLE 5 0 0 HENRY SCHEIN INC COM 806407102 8825 134267 SH DFND 1 134267 0 0 HENRY SCHEIN INC COM 806407102 17675 268915 SH DFND 2 268915 0 0 HENRY SCHEIN INC COM 806407102 1 12 SH SOLE 12 0 0 HERBALIFE NUTRITION LTD COM SHS G4412G101 618 12900 SH DFND 2 12900 0 0 HERSHEY CO COM 427866108 6997 45506 SH DFND 1 45506 0 0 HERSHEY CO COM 427866108 16597 107938 SH DFND 2 107938 0 0 HERSHEY CO COM 427866108 2 10 SH SOLE 10 0 0 HESS CORP COM 42809H107 1088 20761 SH DFND 1 20761 0 0 HESS CORP COM 42809H107 1551 29600 SH DFND 2 29600 0 0 HEWLETT PACKARD ENTERPRISE C COM 42824C109 2358 198702 SH DFND 1 198702 0 0 HEWLETT PACKARD ENTERPRISE C COM 42824C109 826 69651 SH DFND 2 69651 0 0 HEWLETT PACKARD ENTERPRISE C COM 42824C109 7 585 SH SOLE 585 0 0 HEXCEL CORP NEW COM 428291108 141 2945 SH DFND 1 2945 0 0 HIGHWOODS PPTYS INC COM 431284108 468 12346 SH DFND 1 12346 0 0 HILL ROM HLDGS INC COM 431475102 1203 12300 SH DFND 1 12300 0 0 HILTON WORLDWIDE HLDGS INC COM 43300A203 3800 35307 SH DFND 1 35307 0 0 HILTON WORLDWIDE HLDGS INC COM 43300A203 2 19 SH SOLE 19 0 0 HOLLYFRONTIER CORP COM 436106108 339 13396 SH DFND 1 13396 0 0 HOLLYFRONTIER CORP COM 436106108 755 29800 SH DFND 2 29800 0 0 HOLOGIC INC COM 436440101 21927 304694 SH DFND 1 304694 0 0 HOLOGIC INC COM 436440101 8568 119054 SH DFND 2 119054 0 0 HOLOGIC INC COM 436440101 2 24 SH SOLE 24 0 0 HOME DEPOT INC COM 437076102 126115 470600 SH DFND 1 470600 0 0 HOME DEPOT INC COM 437076102 31146 116221 SH DFND 2 116221 0 0 HOMOLOGY MEDICINES INC COM 438083107 436 38500 SH DFND 2 38500 0 0 HONEYWELL INTL INC COM 438516106 102083 487912 SH DFND 1 487912 0 0 HONEYWELL INTL INC COM 438516106 61949 296089 SH DFND 2 296089 0 0 HORIZON THERAPEUTICS PUB L SHS G46188101 1791 25757 SH DFND 1 25757 0 0 HORIZON THERAPEUTICS PUB L SHS G46188101 9977 143450 SH DFND 2 143450 0 0 HORMEL FOODS CORP COM 440452100 11307 240030 SH DFND 1 240030 0 0 HORMEL FOODS CORP COM 440452100 15573 330586 SH DFND 2 330586 0 0 HORMEL FOODS CORP COM 440452100 1 12 SH SOLE 12 0 0 HOST HOTELS & RESORTS INC COM 44107P104 4187 290908 SH DFND 1 290908 0 0 HOST HOTELS & RESORTS INC COM 44107P104 1 51 SH SOLE 51 0 0 HOWMET AEROSPACE INC COM 443201108 1763 63422 SH DFND 1 63422 0 0 HOWMET AEROSPACE INC COM 443201108 1 18 SH SOLE 18 0 0 HP INC COM 40434L105 11630 482357 SH DFND 1 482357 0 0 HP INC COM 40434L105 2334 96801 SH DFND 2 96801 0 0 HP INC COM 40434L105 2 98 SH SOLE 98 0 0 HUAZHU GROUP LTD SPONSORED ADS 44332N106 883 20287 SH DFND 1 20287 0 0 HUAZHU GROUP LTD SPONSORED ADS 44332N106 6596 151476 SH DFND 2 151476 0 0 HUBBELL INC COM 443510607 1693 10839 SH DFND 1 10839 0 0 HUBBELL INC COM 443510607 2567 16432 SH DFND 2 16432 0 0 HUBSPOT INC COM 443573100 1045 2674 SH DFND 1 2674 0 0 HUDSON PAC PPTYS INC COM 444097109 1956 83691 SH DFND 1 83691 0 0 HUMANA INC COM 444859102 9864 24153 SH DFND 1 24153 0 0 HUMANA INC COM 444859102 6250 15303 SH DFND 2 15303 0 0 HUMANA INC COM 444859102 4 10 SH SOLE 10 0 0 HUNT J B TRANS SVCS INC COM 445658107 1512 11120 SH DFND 1 11120 0 0 HUNT J B TRANS SVCS INC COM 445658107 2116 15558 SH DFND 2 15558 0 0 HUNT J B TRANS SVCS INC COM 445658107 1 6 SH SOLE 6 0 0 HUNTINGTON BANCSHARES INC COM 446150104 2219 181297 SH DFND 1 181297 0 0 HUNTINGTON BANCSHARES INC COM 446150104 1 76 SH SOLE 76 0 0 HUNTINGTON INGALLS INDS INC COM 446413106 839 5052 SH DFND 1 5052 0 0 HUTCHISON CHINA MEDITECH LTD SPONSORED ADR 44842L103 96 3333 SH DFND 1 3333 0 0 HUTCHISON CHINA MEDITECH LTD SPONSORED ADR 44842L103 489 17000 SH DFND 2 17000 0 0 HUYA INC ADS REP SHS A 44852D108 499 25121 SH DFND 1 25121 0 0 HYDROFARM HLDGS GROUP INC COM 44888K209 2629 55300 SH DFND 1 55300 0 0 I MAB SPONSORED ADS 44975P103 195 4800 SH DFND 2 4800 0 0 IAC INTERACTIVECORP NEW COM 44891N109 1297 7030 SH DFND 1 7030 0 0 ICICI BANK LIMITED ADR 45104G104 553 38400 SH DFND 1 38400 0 0 ICL GROUP LTD SHS M53213100 277 55439 SH DFND 1 55439 0 0 ICL GROUP LTD SHS M53213100 0 34 SH SOLE 34 0 0 ICON PLC SHS G4705A100 260 1357 SH DFND 1 1357 0 0 ICU MED INC COM 44930G107 600 2804 SH DFND 1 2804 0 0 IDACORP INC COM 451107106 482 5019 SH DFND 1 5019 0 0 IDACORP INC COM 451107106 3434 35791 SH DFND 2 35791 0 0 IDEAYA BIOSCIENCES INC COM 45166A102 124 10000 SH DFND 2 10000 0 0 IDEX CORP COM 45167R104 1762 9006 SH DFND 1 9006 0 0 IDEX CORP COM 45167R104 4446 22729 SH DFND 2 22729 0 0 IDEX CORP COM 45167R104 1 6 SH SOLE 6 0 0 IDEXX LABS INC COM 45168D104 8803 17810 SH DFND 1 17810 0 0 IDEXX LABS INC COM 45168D104 1601 3240 SH DFND 2 3240 0 0 IDEXX LABS INC COM 45168D104 3 7 SH SOLE 7 0 0 IGM BIOSCIENCES INC COM 449585108 707 8100 SH DFND 2 8100 0 0 IHS MARKIT LTD SHS G47567105 5390 61717 SH DFND 1 61717 0 0 IHS MARKIT LTD SHS G47567105 702 8038 SH DFND 2 8038 0 0 IHS MARKIT LTD SHS G47567105 3 31 SH SOLE 31 0 0 ILLINOIS TOOL WKS INC COM 452308109 15283 76220 SH DFND 1 76220 0 0 ILLINOIS TOOL WKS INC COM 452308109 12949 64580 SH DFND 2 64580 0 0 ILLINOIS TOOL WKS INC COM 452308109 4 19 SH SOLE 19 0 0 ILLUMINA INC COM 452327109 12847 34888 SH DFND 1 34888 0 0 ILLUMINA INC COM 452327109 26547 72090 SH DFND 2 72090 0 0 ILLUMINA INC COM 452327109 4 10 SH SOLE 10 0 0 IMMUNOGEN INC COM 45253H101 402 62000 SH DFND 2 62000 0 0 IMMUNOVANT INC COM 45258J102 1378 28600 SH DFND 2 28600 0 0 IMPERIAL OIL LTD COM NEW 453038408 181 9551 SH DFND 1 9551 0 0 INCYTE CORP COM 45337C102 1952 22638 SH DFND 1 22638 0 0 INCYTE CORP COM 45337C102 5017 58170 SH DFND 2 58170 0 0 INCYTE CORP COM 45337C102 1 11 SH SOLE 11 0 0 INFOSYS LTD SPONSORED ADR 456788108 616 37100 SH DFND 1 37100 0 0 INFOSYS LTD SPONSORED ADR 456788108 1287 77500 SH DFND 2 77500 0 0 INGERSOLL RAND INC COM 45687V106 4880 110205 SH DFND 1 110205 0 0 INGERSOLL RAND INC COM 45687V106 486 10978 SH DFND 2 10978 0 0 INGERSOLL RAND INC COM 45687V106 1 27 SH SOLE 27 0 0 INGREDION INC COM 457187102 270 3400 SH DFND 1 3400 0 0 INGREDION INC COM 457187102 4517 56933 SH DFND 2 56933 0 0 INGREDION INC COM 457187102 5 59 SH SOLE 59 0 0 INNOVIVA INC COM 45781M101 451 37200 SH DFND 2 37200 0 0 INOVIO PHARMACEUTICALS INC COM NEW 45773H201 478 54000 SH DFND 2 54000 0 0 INOZYME PHARMA INC COM 45790W108 170 7000 SH DFND 2 7000 0 0 INSMED INC COM PAR $. 01 457669307 4373 130700 SH DFND 2 130700 0 0 INSULET CORP COM 45784P101 1069 4167 SH DFND 1 4167 0 0 INSULET CORP COM 45784P101 0 1 SH SOLE 1 0 0 INTEL CORP COM 458140100 112917 2297078 SH DFND 1 2297078 0 0 INTEL CORP COM 458140100 32211 655272 SH DFND 2 655272 0 0 INTELLIA THERAPEUTICS INC COM 45826J105 1022 18800 SH DFND 2 18800 0 0 INTERACTIVE BROKERS GROUP IN COM CL A 45841N107 94 1553 SH DFND 1 1553 0 0 INTERCEPT PHARMACEUTICALS IN COM 45845P108 270 11090 SH DFND 2 11090 0 0 INTERCONTINENTAL EXCHANGE IN COM 45866F104 29952 263227 SH DFND 1 263227 0 0 INTERCONTINENTAL EXCHANGE IN COM 45866F104 1126 9899 SH DFND 2 9899 0 0 INTERCONTINENTAL EXCHANGE IN COM 45866F104 6 55 SH SOLE 55 0 0 INTERNATIONAL BUSINESS MACHS COM 459200101 47208 380336 SH DFND 1 380336 0 0 INTERNATIONAL BUSINESS MACHS COM 459200101 15409 124147 SH DFND 2 124147 0 0 INTERNATIONAL FLAVORS& FRAGRA COM 459506101 30093 273331 SH DFND 1 273331 0 0 INTERNATIONAL FLAVORS& FRAGRA COM 459506101 5622 51067 SH DFND 2 51067 0 0 INTERNATIONAL FLAVORS& FRAGRA COM 459506101 0 4 SH SOLE 4 0 0 INTERNATIONAL PAPER CO COM 460146103 6818 139483 SH DFND 1 139483 0 0 INTERNATIONAL PAPER CO COM 460146103 2273 46500 SH DFND 2 46500 0 0 INTERNATIONAL PAPER CO COM 460146103 1 17 SH SOLE 17 0 0 INTERPUBLIC GROUP COS INC COM 460690100 1556 65526 SH DFND 1 65526 0 0 INTERPUBLIC GROUP COS INC COM 460690100 1 24 SH SOLE 24 0 0 INTRA CELLULAR THERAPIES INC COM 46116X101 953 30900 SH DFND 2 30900 0 0 INTUIT COM 461202103 50247 132167 SH DFND 1 132167 0 0 INTUIT COM 461202103 13956 36709 SH DFND 2 36709 0 0 INTUIT COM 461202103 7 18 SH SOLE 18 0 0 INTUITIVE SURGICAL INC COM NEW 46120E602 17258 20939 SH DFND 1 20939 0 0 INTUITIVE SURGICAL INC COM NEW 46120E602 29243 35480 SH DFND 2 35480 0 0 INTUITIVE SURGICAL INC COM NEW 46120E602 5 6 SH SOLE 6 0 0 INVESCO LTD SHS G491BT108 732 43296 SH DFND 1 43296 0 0 INVESCO LTD SHS G491BT108 0 22 SH SOLE 22 0 0 INVITATION HOMES INC COM 46187W107 6780 233526 SH DFND 1 233526 0 0 INVITATION HOMES INC COM 46187W107 0 12 SH SOLE 12 0 0 IONIS PHARMACEUTICALS INC COM 462222100 489 8563 SH DFND 1 8563 0 0 IONIS PHARMACEUTICALS INC COM 462222100 6140 107576 SH DFND 2 107576 0 0 IONIS PHARMACEUTICALS INC COM 462222100 1 11 SH SOLE 11 0 0 IOVANCE BIOTHERAPEUTICS INC COM 462260100 3054 63600 SH DFND 2 63600 0 0 IPG PHOTONICS CORP COM 44980X109 1781 8070 SH DFND 1 8070 0 0 IPG PHOTONICS CORP COM 44980X109 46896 212500 SH DFND 2 212500 0 0 IPG PHOTONICS CORP COM 44980X109 0 2 SH SOLE 2 0 0 IQIYI INC SPONSORED ADS 46267X108 235 13105 SH DFND 1 13105 0 0 IQVIA HLDGS INC COM 46266C105 4793 27440 SH DFND 1 27440 0 0 IQVIA HLDGS INC COM 46266C105 4716 27000 SH DFND 2 27000 0 0 IQVIA HLDGS INC COM 46266C105 3 16 SH SOLE 16 0 0 IRON MTN INC NEW COM 46284V101 1698 55228 SH DFND 1 55228 0 0 IRON MTN INC NEW COM 46284V101 1 19 SH SOLE 19 0 0 ITAU CORPBANCA SPONSORED ADR 45033E105 18 3710 SH DFND 1 3710 0 0 ITAU UNIBANCO HLDG S A SPON ADR REP PFD 465562106 243 40146 SH DFND 1 40146 0 0 ITEOS THERAPEUTICS INC COM 46565G104 330 10000 SH DFND 2 10000 0 0 IVERIC BIO INC COM 46583P102 181 28000 SH DFND 2 28000 0 0 J2 GLOBAL INC COM 48123V102 384 3900 SH DFND 1 3900 0 0 J2 GLOBAL INC COM 48123V102 876 8900 SH DFND 2 8900 0 0 JABIL INC COM 466313103 430 10346 SH DFND 1 10346 0 0 JABIL INC COM 466313103 823 19795 SH DFND 2 19795 0 0 JAZZ PHARMACEUTICALS PLC SHS USD G50871105 1298 8117 SH DFND 1 8117 0 0 JAZZ PHARMACEUTICALS PLC SHS USD G50871105 9691 60599 SH DFND 2 60599 0 0 JBG SMITH PPTYS COM 46590V100 122 4101 SH DFND 1 4101 0 0 JD. COM INC SPON ADR CL A 47215P106 27140 310739 SH DFND 1 310739 0 0 JD. COM INC SPON ADR CL A 47215P106 699 8000 SH DFND 2 8000 0 0 JINKOSOLAR HLDG CO LTD SPONSORED ADR 47759T100 282 4124 SH DFND 1 4124 0 0 JINKOSOLAR HLDG CO LTD SPONSORED ADR 47759T100 120 1750 SH DFND 2 1750 0 0 JOHNSON & JOHNSON COM 478160104 271082 1743394 SH DFND 1 1743394 0 0 JOHNSON & JOHNSON COM 478160104 81571 524605 SH DFND 2 524605 0 0 JOHNSON CTLS INTL PLC SHS G51502105 35635 781439 SH DFND 1 781439 0 0 JOHNSON CTLS INTL PLC SHS G51502105 29709 651487 SH DFND 2 651487 0 0 JOHNSON CTLS INTL PLC SHS G51502105 4 80 SH SOLE 80 0 0 JONES LANG LASALLE INC COM 48020Q107 2051 13666 SH DFND 1 13666 0 0 JONES LANG LASALLE INC COM 48020Q107 11 75 SH SOLE 75 0 0 JOYY INC ADS REPSTG COM A 46591M109 612 7895 SH DFND 1 7895 0 0 JPMORGAN CHASE & CO COM 46625H100 253983 2020605 SH DFND 1 2020605 0 0 JPMORGAN CHASE & CO COM 46625H100 22623 179980 SH DFND 2 179980 0 0 JUMIA TECHNOLOGIES AG SPONSORED ADS 48138M105 4859 125000 SH DFND 1 125000 0 0 JUMIA TECHNOLOGIES AG SPONSORED ADS 48138M105 8828 227100 SH DFND 2 227100 0 0 JUNIPER NETWORKS INC COM 48203R104 1025 46458 SH DFND 1 46458 0 0 JUNIPER NETWORKS INC COM 48203R104 0 22 SH SOLE 22 0 0 KADMON HLDGS INC COM 48283N106 221 55000 SH DFND 2 55000 0 0 KALA PHARMACEUTICALS INC COM 483119103 143 20000 SH DFND 2 20000 0 0 KANSAS CITY SOUTHERN COM NEW 485170302 14257 71541 SH DFND 1 71541 0 0 KANSAS CITY SOUTHERN COM NEW 485170302 1 6 SH SOLE 6 0 0 KARUNA THERAPEUTICS INC COM 48576A100 867 8500 SH DFND 2 8500 0 0 KARYOPHARM THERAPEUTICS INC COM 48576U106 547 36200 SH DFND 2 36200 0 0 KB FINL GROUP INC SPONSORED ADR 48241A105 260 6636 SH DFND 1 6636 0 0 KB FINL GROUP INC SPONSORED ADR 48241A105 752 19235 SH DFND 2 19235 0 0 KB HOME COM 48666K109 310 8940 SH DFND 1 8940 0 0 KE HLDGS INC SPONSORED ADS 482497104 267 4295 SH DFND 1 4295 0 0 KELLOGG CO COM 487836108 17309 277699 SH DFND 1 277699 0 0 KELLOGG CO COM 487836108 27794 445904 SH DFND 2 445904 0 0 KELLOGG CO COM 487836108 1 16 SH SOLE 16 0 0 KEROS THERAPEUTICS INC COM 492327101 496 6650 SH DFND 2 6650 0 0 KEURIG DR PEPPER INC COM 49271V100 2179 67758 SH DFND 1 67758 0 0 KEURIG DR PEPPER INC COM 49271V100 609 18929 SH DFND 2 18929 0 0 KEYCORP COM 493267108 2197 138435 SH DFND 1 138435 0 0 KEYCORP COM 493267108 1 62 SH SOLE 62 0 0 KEYSIGHT TECHNOLOGIES INC COM 49338L103 27052 205523 SH DFND 1 205523 0 0 KEYSIGHT TECHNOLOGIES INC COM 49338L103 48220 366339 SH DFND 2 366339 0 0 KEYSIGHT TECHNOLOGIES INC COM 49338L103 1 11 SH SOLE 11 0 0 KILROY RLTY CORP COM 49427F108 1681 30360 SH DFND 1 30360 0 0 KIMBERLY- CLARK CORP COM 494368103 30181 222834 SH DFND 1 222834 0 0 KIMBERLY- CLARK CORP COM 494368103 47601 351456 SH DFND 2 351456 0 0 KIMBERLY- CLARK CORP COM 494368103 2 17 SH SOLE 17 0 0 KIMCO RLTY CORP COM 49446R109 3096 214845 SH DFND 1 214845 0 0 KINDER MORGAN INC DEL COM 49456B101 9251 672675 SH DFND 1 672675 0 0 KINDER MORGAN INC DEL COM 49456B101 1333 96939 SH DFND 2 96939 0 0 KINDER MORGAN INC DEL COM 49456B101 7 515 SH SOLE 515 0 0 KINGSOFT CLOUD HLDGS LTD ADS 49639K101 1047 2556 SH DFND 1 2556 0 0 KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 175 10000 SH DFND 2 10000 0 0 KINROSS GOLD CORP COM 496902404 2491 337056 SH DFND 1 337056 0 0 KINROSS GOLD CORP COM 496902404 134 18100 SH DFND 2 18100 0 0 KIRKLAND LAKE GOLD LTD COM 49741E100 2216 53369 SH DFND 1 53369 0 0 KIRKLAND LAKE GOLD LTD COM 49741E100 1532 36900 SH DFND 2 36900 0 0 KIRKLAND LAKE GOLD LTD COM 49741E100 1 23 SH SOLE 23 0 0 KKR & CO INC COM 48251W104 1 35 SH SOLE 35 0 0 KLA CORP COM NEW 482480100 8670 34016 SH DFND 1 34016 0 0 KLA CORP COM NEW 482480100 3 12 SH SOLE 12 0 0 KNIGHT- SWIFT TRANSN HLDGS IN CL A 499049104 10946 258668 SH DFND 1 258668 0 0 KNIGHT- SWIFT TRANSN HLDGS IN CL A 499049104 4909 116000 SH DFND 2 116000 0 0 KNIGHT- SWIFT TRANSN HLDGS IN CL A 499049104 0 10 SH SOLE 10 0 0 KODIAK SCIENCES INC COM 50015M109 691 4760 SH DFND 2 4760 0 0 KOHLS CORP COM 500255104 486 12200 SH DFND 1 12200 0 0 KOHLS CORP COM 500255104 1112 27900 SH DFND 2 27900 0 0 KONTOOR BRANDS INC COM 50050N103 7 171 SH DFND 1 171 0 0 KONTOOR BRANDS INC COM 50050N103 0 1 SH SOLE 1 0 0 KOREA ELECTRIC PWR SPONSORED ADR 500631106 430 34974 SH DFND 1 34974 0 0 KORNIT DIGITAL LTD SHS M6372Q113 3034 34014 SH DFND 1 34014 0 0 KRAFT HEINZ CO COM 500754106 3213 91435 SH DFND 1 91435 0 0 KRAFT HEINZ CO COM 500754106 773 22000 SH DFND 2 22000 0 0 KRAFT HEINZ CO COM 500754106 1 32 SH SOLE 32 0 0 KROGER CO COM 501044101 10836 344291 SH DFND 1 344291 0 0 KROGER CO COM 501044101 30499 969045 SH DFND 2 969045 0 0 KROGER CO COM 501044101 1 29 SH SOLE 29 0 0 KRYSTAL BIOTECH INC COM 501147102 361 6400 SH DFND 2 6400 0 0 KURA ONCOLOGY INC COM 50127T109 2258 67000 SH DFND 2 67000 0 0 L BRANDS INC COM 501797104 29 777 SH DFND 1 777 0 0 L3HARRIS TECHNOLOGIES INC COM 502431109 8130 43770 SH DFND 1 43770 0 0 L3HARRIS TECHNOLOGIES INC COM 502431109 7932 42700 SH DFND 2 42700 0 0 LABORATORY CORP AMER HLDGS COM NEW 50540R409 4224 20935 SH DFND 1 20935 0 0 LABORATORY CORP AMER HLDGS COM NEW 50540R409 4120 20423 SH DFND 2 20423 0 0 LABORATORY CORP AMER HLDGS COM NEW 50540R409 1 7 SH SOLE 7 0 0 LAM RESEARCH CORP COM 512807108 34178 72175 SH DFND 1 72175 0 0 LAM RESEARCH CORP COM 512807108 13764 29065 SH DFND 2 29065 0 0 LAM RESEARCH CORP COM 512807108 5 10 SH SOLE 10 0 0 LAMAR ADVERTISING CO NEW CL A 512816109 130 1598 SH DFND 1 1598 0 0 LAMB WESTON HLDGS INC COM 513272104 3531 45925 SH DFND 1 45925 0 0 LAMB WESTON HLDGS INC COM 513272104 1 7 SH SOLE 7 0 0 LANDSTAR SYS INC COM 515098101 671 5001 SH DFND 1 5001 0 0 LANDSTAR SYS INC COM 515098101 638 4758 SH DFND 2 4758 0 0 LAS VEGAS SANDS CORP COM 517834107 43765 754468 SH DFND 1 754468 0 0 LAS VEGAS SANDS CORP COM 517834107 1073 18500 SH DFND 2 18500 0 0 LAS VEGAS SANDS CORP COM 517834107 1 24 SH SOLE 24 0 0 LAUDER ESTEE COS INC CL A 518439104 25980 99409 SH DFND 1 99409 0 0 LAUDER ESTEE COS INC CL A 518439104 5149 19700 SH DFND 2 19700 0 0 LAUDER ESTEE COS INC CL A 518439104 3 12 SH SOLE 12 0 0 LEAR CORP COM NEW 521865204 1191 7562 SH DFND 1 7562 0 0 LEAR CORP COM NEW 521865204 830 5272 SH DFND 2 5272 0 0 LEGEND BIOTECH CORP SPONSORED ADS 52490G102 173 6000 SH DFND 2 6000 0 0 LEGGETT & PLATT INC COM 524660107 19 441 SH DFND 1 441 0 0 LEIDOS HOLDINGS INC COM 525327102 2126 20454 SH DFND 1 20454 0 0 LEIDOS HOLDINGS INC COM 525327102 2992 28785 SH DFND 2 28785 0 0 LENNAR CORP CL A 526057104 3644 47016 SH DFND 1 47016 0 0 LENNAR CORP CL A 526057104 1 19 SH SOLE 19 0 0 LENNAR CORP CL B 526057302 12 196 SH DFND 1 196 0 0 LENNOX INTL INC COM 526107107 1371 5111 SH DFND 1 5111 0 0 LENNOX INTL INC COM 526107107 3948 14720 SH DFND 2 14720 0 0 LENNOX INTL INC COM 526107107 1 3 SH SOLE 3 0 0 LHC GROUP INC COM 50187A107 106 500 SH DFND 1 500 0 0 LHC GROUP INC COM 50187A107 296 1400 SH DFND 2 1400 0 0 LIBERTY BROADBAND CORP COM SER A 530307107 341 2163 SH DFND 1 2163 0 0 LIBERTY BROADBAND CORP COM SER A 530307107 0 1 SH SOLE 1 0 0 LIBERTY BROADBAND CORP COM SER C 530307305 2194 13824 SH DFND 1 13824 0 0 LIBERTY BROADBAND CORP COM SER C 530307305 1 7 SH SOLE 7 0 0 LIBERTY GLOBAL PLC SHS CL A G5480U104 443 18174 SH DFND 1 18174 0 0 LIBERTY GLOBAL PLC SHS CL C G5480U120 954 40613 SH DFND 1 40613 0 0 LIBERTY MEDIA CORP DEL COM A SIRIUSXM 531229409 418 9821 SH DFND 1 9821 0 0 LIBERTY MEDIA CORP DEL COM A SIRIUSXM 531229409 6 130 SH SOLE 130 0 0 LIBERTY MEDIA CORP DEL COM C SIRIUSXM 531229607 421 9824 SH DFND 1 9824 0 0 LIBERTY MEDIA CORP DEL COM C SIRIUSXM 531229607 11 259 SH SOLE 259 0 0 LIBERTY MEDIA CORP DEL COM SER C FRMLA 531229854 534 12470 SH DFND 1 12470 0 0 LIBERTY MEDIA CORP DEL COM SER C FRMLA 531229854 13 303 SH SOLE 303 0 0 LIFE STORAGE INC COM 53223X107 3331 27914 SH DFND 1 27914 0 0 LIFE STORAGE INC COM 53223X107 1773 14862 SH DFND 2 14862 0 0 LIGAND PHARMACEUTICALS INC COM NEW 53220K504 396 4040 SH DFND 2 4040 0 0 LILLY ELI & CO COM 532457108 66391 399362 SH DFND 1 399362 0 0 LILLY ELI & CO COM 532457108 73431 441712 SH DFND 2 441712 0 0 LILLY ELI & CO COM 532457108 10 59 SH SOLE 59 0 0 LINCOLN NATL CORP IND COM 534187109 3859 78828 SH DFND 1 78828 0 0 LINCOLN NATL CORP IND COM 534187109 940 19200 SH DFND 2 19200 0 0 LINCOLN NATL CORP IND COM 534187109 1 18 SH SOLE 18 0 0 LINDE PLC SHS G5494J103 1068966 4089280 SH DFND 1 4089280 0 0 LINDE PLC SHS G5494J103 116439 445433 SH DFND 2 445433 0 0 LINDE PLC SHS G5494J103 63 240 SH SOLE 240 0 0 LINDE PLC SHS G5494J103 0 46700 SH Call DFND 1 46700 0 0 LITTELFUSE INC COM 537008104 55103 221750 SH DFND 2 221750 0 0 LIVE NATION ENTERTAINMENT IN COM 538034109 850 11404 SH DFND 1 11404 0 0 LIVE NATION ENTERTAINMENT IN COM 538034109 1 8 SH SOLE 8 0 0 LKQ CORP COM 501889208 1701 48702 SH DFND 1 48702 0 0 LKQ CORP COM 501889208 505 14465 SH DFND 2 14465 0 0 LKQ CORP COM 501889208 1 24 SH SOLE 24 0 0 LOEWS CORP COM 540424108 1367 31051 SH DFND 1 31051 0 0 LOEWS CORP COM 540424108 0 7 SH SOLE 7 0 0 LOGITECH INTL S A SHS H50430232 34298 352389 SH DFND 1 352389 0 0 LOGITECH INTL S A SHS H50430232 9080 93286 SH DFND 2 93286 0 0 LORDSTOWN MOTORS CORP COM CL A 54405Q100 2988 140000 SH DFND 1 140000 0 0 LOWES COS INC COM 548661107 28423 176917 SH DFND 1 176917 0 0 LOWES COS INC COM 548661107 4059 25267 SH DFND 2 25267 0 0 LOWES COS INC COM 548661107 11 69 SH SOLE 69 0 0 LTC PPTYS INC COM 502175102 1916 49456 SH DFND 1 49456 0 0 LUFAX HOLDING LTD ADS REP SHS CL A 54975P102 1107 8009 SH DFND 1 8009 0 0 LULULEMON ATHLETICA INC COM 550021109 6864 19471 SH DFND 1 19471 0 0 LULULEMON ATHLETICA INC COM 550021109 3 9 SH SOLE 9 0 0 LUMEN TECHNOLOGIES INC COM 156700106 1051 106831 SH DFND 1 106831 0 0 LUMEN TECHNOLOGIES INC COM 156700106 1 56 SH SOLE 56 0 0 LUMENTUM HLDGS INC COM 55024U109 105 1100 SH DFND 1 1100 0 0 LUMINAR TECHNOLOGIES INC COM CL A 550424105 1456 45000 SH DFND 1 45000 0 0 LUMINEX CORP DEL COM 55027E102 396 17300 SH DFND 2 17300 0 0 LYFT INC CL A COM 55087P104 4537 92748 SH DFND 1 92748 0 0 LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 3581 38980 SH DFND 1 38980 0 0 LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 2618 28490 SH DFND 2 28490 0 0 LYONDELLBASELL INDUSTRIES N SHS - A - N53745100 0 5 SH SOLE 5 0 0 M & T BK CORP COM 55261F104 2610 21220 SH DFND 1 21220 0 0 M & T BK CORP COM 55261F104 1 12 SH SOLE 12 0 0 MACOM TECH SOLUTIONS HLDGS I COM 55405Y100 1441 27500 SH DFND 1 27500 0 0 MACROGENICS INC COM 556099109 363 16200 SH DFND 2 16200 0 0 MADRIGAL PHARMACEUTICALS INC COM 558868105 515 4750 SH DFND 2 4750 0 0 MAGNA INTL INC COM 559222401 2368 32625 SH DFND 1 32625 0 0 MAGNA INTL INC COM 559222401 8542 117698 SH DFND 2 117698 0 0 MANNKIND CORP COM NEW 56400P706 178 55000 SH DFND 2 55000 0 0 MANULIFE FINL CORP COM 56501R106 100413 5668536 SH DFND 1 5668536 0 0 MANULIFE FINL CORP COM 56501R106 11583 653882 SH DFND 2 653882 0 0 MARATHON OIL CORP COM 565849106 17 2629 SH DFND 1 2629 0 0 MARATHON OIL CORP COM 565849106 85 13000 SH DFND 2 13000 0 0 MARATHON PETE CORP COM 56585A102 5068 124946 SH DFND 1 124946 0 0 MARATHON PETE CORP COM 56585A102 1158 28558 SH DFND 2 28558 0 0 MARATHON PETE CORP COM 56585A102 0 7 SH SOLE 7 0 0 MARKEL CORP COM 570535104 1419 1434 SH DFND 1 1434 0 0 MARKEL CORP COM 570535104 1 1 SH SOLE 1 0 0 MARKETAXESS HLDGS INC COM 57060D108 1618 2878 SH DFND 1 2878 0 0 MARKETAXESS HLDGS INC COM 57060D108 2 3 SH SOLE 3 0 0 MARRIOTT INTL INC NEW CL A 571903202 4013 31072 SH DFND 1 31072 0 0 MARRIOTT INTL INC NEW CL A 571903202 2 18 SH SOLE 18 0 0 MARSH & MCLENNAN COS INC COM 571748102 116945 1016748 SH DFND 1 1016748 0 0 MARSH & MCLENNAN COS INC COM 571748102 21246 184721 SH DFND 2 184721 0 0 MARSH & MCLENNAN COS INC COM 571748102 4 33 SH SOLE 33 0 0 MARTIN MARIETTA MATLS INC COM 573284106 54154 198298 SH DFND 1 198298 0 0 MARTIN MARIETTA MATLS INC COM 573284106 3359 12300 SH DFND 2 12300 0 0 MARTIN MARIETTA MATLS INC COM 573284106 1 3 SH SOLE 3 0 0 MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 4563 98891 SH DFND 1 98891 0 0 MARVELL TECHNOLOGY GROUP LTD ORD G5876H105 2 50 SH SOLE 50 0 0 MASCO CORP COM 574599106 16599 303916 SH DFND 1 303916 0 0 MASCO CORP COM 574599106 6461 118284 SH DFND 2 118284 0 0 MASCO CORP COM 574599106 2 39 SH SOLE 39 0 0 MASIMO CORP COM 574795100 1444 5434 SH DFND 1 5434 0 0 MASIMO CORP COM 574795100 1 3 SH SOLE 3 0 0 MASTEC INC COM 576323109 451 6600 SH DFND 1 6600 0 0 MASTEC INC COM 576323109 1038 15200 SH DFND 2 15200 0 0 MASTERCARD INCORPORATED CL A 57636Q104 134183 384283 SH DFND 1 384283 0 0 MASTERCARD INCORPORATED CL A 57636Q104 25819 73941 SH DFND 2 73941 0 0 MATCH GROUP INC NEW COM 57667L107 5302 34479 SH DFND 1 34479 0 0 MAXIM INTEGRATED PRODS INC COM 57772K101 13458 156291 SH DFND 1 156291 0 0 MAXIM INTEGRATED PRODS INC COM 57772K101 26245 304788 SH DFND 2 304788 0 0 MAXIM INTEGRATED PRODS INC COM 57772K101 11 122 SH SOLE 122 0 0 MAXIMUS INC COM 577933104 12518 172479 SH DFND 1 172479 0 0 MAXIMUS INC COM 577933104 11431 157500 SH DFND 2 157500 0 0 MCCORMICK & CO INC COM NON VTG 579780206 4845 50441 SH DFND 1 50441 0 0 MCCORMICK & CO INC COM NON VTG 579780206 8 86 SH SOLE 86 0 0 MCDONALDS CORP COM 580135101 65954 308130 SH DFND 1 308130 0 0 MCDONALDS CORP COM 580135101 9845 45993 SH DFND 2 45993 0 0 MCDONALDS CORP COM 580135101 11 53 SH SOLE 53 0 0 MCKESSON CORP COM 58155Q103 5586 32048 SH DFND 1 32048 0 0 MCKESSON CORP COM 58155Q103 9844 56482 SH DFND 2 56482 0 0 MCKESSON CORP COM 58155Q103 2 11 SH SOLE 11 0 0 MDU RES GROUP INC COM 552690109 3601 142107 SH DFND 1 142107 0 0 MEDICAL PPTYS TRUST INC COM 58463J304 3389 157569 SH DFND 1 157569 0 0 MEDICAL PPTYS TRUST INC COM 58463J304 0 20 SH SOLE 20 0 0 MEDPACE HLDGS INC COM 58506Q109 2035 14900 SH DFND 2 14900 0 0 MEDTRONIC PLC SHS G5960L103 129879 1119497 SH DFND 1 1119497 0 0 MEDTRONIC PLC SHS G5960L103 55800 480974 SH DFND 2 480974 0 0 MEDTRONIC PLC SHS G5960L103 10 90 SH SOLE 90 0 0 MEIRAGTX HLDGS PLC COM G59665102 246 16000 SH DFND 2 16000 0 0 MELCO RESORTS AND ENTMNT LTD ADR 585464100 370 20050 SH DFND 1 20050 0 0 MELCO RESORTS AND ENTMNT LTD ADR 585464100 0 20 SH SOLE 20 0 0 MERCADOLIBRE INC COM 58733R102 21530 12747 SH DFND 1 12747 0 0 MERCADOLIBRE INC COM 58733R102 55056 32597 SH DFND 2 32597 0 0 MERCADOLIBRE INC COM 58733R102 5 3 SH SOLE 3 0 0 MERCK & CO. INC COM 58933Y105 249933 3069078 SH DFND 1 3069078 0 0 MERCK & CO. INC COM 58933Y105 92505 1135919 SH DFND 2 1135919 0 0 MERCK & CO. INC COM 58933Y105 15 189 SH SOLE 189 0 0 MERCURY SYS INC COM 589378108 2111 24497 SH DFND 1 24497 0 0 MERITAGE HOMES CORP COM 59001A102 349 4082 SH DFND 1 4082 0 0 MERSANA THERAPEUTICS INC COM 59045L106 568 21000 SH DFND 2 21000 0 0 METLIFE INC COM 59156R108 4759 103444 SH DFND 1 103444 0 0 METLIFE INC COM 59156R108 850 18481 SH DFND 2 18481 0 0 METLIFE INC COM 59156R108 3 67 SH SOLE 67 0 0 METTLER TOLEDO INTERNATIONAL COM 592688105 21076 18623 SH DFND 1 18623 0 0 METTLER TOLEDO INTERNATIONAL COM 592688105 443 391 SH DFND 2 391 0 0 METTLER TOLEDO INTERNATIONAL COM 592688105 2 2 SH SOLE 2 0 0 MGIC INVT CORP WIS COM 552848103 361 29500 SH DFND 1 29500 0 0 MGIC INVT CORP WIS COM 552848103 826 67500 SH DFND 2 67500 0 0 MGM GROWTH PPTYS LLC CL A COM 55303A105 111 3650 SH DFND 1 3650 0 0 MGM RESORTS INTERNATIONAL COM 552953101 1317 42817 SH DFND 1 42817 0 0 MGM RESORTS INTERNATIONAL COM 552953101 1 31 SH SOLE 31 0 0 MICROCHIP TECHNOLOGY INC. COM 595017104 14619 108077 SH DFND 1 108077 0 0 MICROCHIP TECHNOLOGY INC. COM 595017104 77089 569900 SH DFND 2 569900 0 0 MICRON TECHNOLOGY INC COM 595112103 35666 506072 SH DFND 1 506072 0 0 MICRON TECHNOLOGY INC COM 595112103 8628 122424 SH DFND 2 122424 0 0 MICROSOFT CORP COM 594918104 976487 4340998 SH DFND 1 4340998 0 0 MICROSOFT CORP COM 594918104 178239 792365 SH DFND 2 792365 0 0 MID- AMER APT CMNTYS INC COM 59522J103 3955 31832 SH DFND 1 31832 0 0 MID- AMER APT CMNTYS INC COM 59522J103 1 7 SH SOLE 7 0 0 MIMECAST LTD ORD SHS G14838109 413 7325 SH DFND 1 7325 0 0 MIRATI THERAPEUTICS INC COM 60468T105 1394 6350 SH DFND 1 6350 0 0 MIRATI THERAPEUTICS INC COM 60468T105 3566 16240 SH DFND 2 16240 0 0 MKS INSTRS INC COM 55306N104 976 6500 SH DFND 1 6500 0 0 MOBILE TELESYSTEMS PJSC SPONSORED ADR 607409109 319 35470 SH DFND 1 35470 0 0 MODERNA INC COM 60770K107 8904 75400 SH DFND 1 75400 0 0 MODERNA INC COM 60770K107 17962 152100 SH DFND 2 152100 0 0 MOHAWK INDS INC COM 608190104 1320 9496 SH DFND 1 9496 0 0 MOHAWK INDS INC COM 608190104 904 6500 SH DFND 2 6500 0 0 MOHAWK INDS INC COM 608190104 1 5 SH SOLE 5 0 0 MOLINA HEALTHCARE INC COM 60855R100 1260 6097 SH DFND 1 6097 0 0 MOLINA HEALTHCARE INC COM 60855R100 1033 5000 SH DFND 2 5000 0 0 MOLINA HEALTHCARE INC COM 60855R100 1 7 SH SOLE 7 0 0 MOLSON COORS BEVERAGE CO CL B 60871R209 5018 110622 SH DFND 1 110622 0 0 MOLSON COORS BEVERAGE CO CL B 60871R209 853 18800 SH DFND 2 18800 0 0 MOLSON COORS BEVERAGE CO CL B 60871R209 0 10 SH SOLE 10 0 0 MOMO INC ADR 60879B107 93 7114 SH DFND 1 7114 0 0 MOMO INC ADR 60879B107 1111 85200 SH DFND 2 85200 0 0 MONDELEZ INTL INC CL A 609207105 15504 265020 SH DFND 1 265020 0 0 MONDELEZ INTL INC CL A 609207105 19714 336986 SH DFND 2 336986 0 0 MONDELEZ INTL INC CL A 609207105 6 98 SH SOLE 98 0 0 MONGODB INC CL A 60937P106 1416 3916 SH DFND 1 3916 0 0 MONOLITHIC PWR SYS INC COM 609839105 7169 20376 SH DFND 1 20376 0 0 MONOLITHIC PWR SYS INC COM 609839105 30960 88000 SH DFND 2 88000 0 0 MONSTER BEVERAGE CORP NEW COM 61174X109 5382 59126 SH DFND 1 59126 0 0 MONTROSE ENVIRONMENTAL GROUP COM 615111101 4936 157500 SH DFND 1 157500 0 0 MOODYS CORP COM 615369105 23348 83116 SH DFND 1 83116 0 0 MOODYS CORP COM 615369105 3 11 SH SOLE 11 0 0 MORGAN STANLEY COM NEW 617446448 133966 1975371 SH DFND 1 1975371 0 0 MORGAN STANLEY COM NEW 617446448 10919 161000 SH DFND 2 161000 0 0 MORGAN STANLEY COM NEW 617446448 14 209 SH SOLE 209 0 0 MORNINGSTAR INC COM 617700109 356 1600 SH DFND 2 1600 0 0 MOSAIC CO NEW COM 61945C103 7184 332849 SH DFND 1 332849 0 0 MOSAIC CO NEW COM 61945C103 0 16 SH SOLE 16 0 0 MOTOROLA SOLUTIONS INC COM NEW 620076307 93282 557819 SH DFND 1 557819 0 0 MOTOROLA SOLUTIONS INC COM NEW 620076307 30211 180660 SH DFND 2 180660 0 0 MOTOROLA SOLUTIONS INC COM NEW 620076307 2 14 SH SOLE 14 0 0 MSA SAFETY INC COM 553498106 3889 26492 SH DFND 1 26492 0 0 MSA SAFETY INC COM 553498106 2138 14564 SH DFND 2 14564 0 0 MSC INDL DIRECT INC CL A 553530106 373 4400 SH DFND 1 4400 0 0 MSC INDL DIRECT INC CL A 553530106 433 5101 SH DFND 2 5101 0 0 MSCI INC COM 55354G100 12250 28218 SH DFND 1 28218 0 0 MSCI INC COM 55354G100 11055 25465 SH DFND 2 25465 0 0 MURPHY USA INC COM 626755102 614 4705 SH DFND 1 4705 0 0 MURPHY USA INC COM 626755102 613 4700 SH DFND 2 4700 0 0 MYRIAD GENETICS INC COM 62855J104 449 24800 SH DFND 2 24800 0 0 NANOSTRING TECHNOLOGIES INC COM 63009R109 825 12650 SH DFND 2 12650 0 0 NANTKWEST INC COM 63016Q102 540 41000 SH DFND 2 41000 0 0 NASDAQ INC COM 631103108 5459 42302 SH DFND 1 42302 0 0 NASDAQ INC COM 631103108 6509 50443 SH DFND 2 50443 0 0 NASDAQ INC COM 631103108 1 9 SH SOLE 9 0 0 NATIONAL HEALTH INVS INC COM 63633D104 2259 32216 SH DFND 1 32216 0 0 NATIONAL INSTRS CORP COM 636518102 2025 47041 SH DFND 1 47041 0 0 NATIONAL OILWELL VARCO INC COM 637071101 17 1293 SH DFND 1 1293 0 0 NATIONAL OILWELL VARCO INC COM 637071101 1 97 SH SOLE 97 0 0 NATIONAL RETAIL PROPERTIES I COM 637417106 124 3026 SH DFND 1 3026 0 0 NATIONAL RETAIL PROPERTIES I COM 637417106 10 244 SH SOLE 244 0 0 NAVIENT CORPORATION COM 63938C108 573 59209 SH DFND 1 59209 0 0 NAVIENT CORPORATION COM 63938C108 743 76700 SH DFND 2 76700 0 0 NAVISTAR INTL CORP NEW COM 63934E108 110 2500 SH DFND 1 2500 0 0 NCR CORP NEW COM 62886E108 502 13700 SH DFND 1 13700 0 0 NCR CORP NEW COM 62886E108 1169 31900 SH DFND 2 31900 0 0 NEKTAR THERAPEUTICS COM 640268108 985 54000 SH DFND 2 54000 0 0 NEOGENOMICS INC COM NEW 64049M209 132 2500 SH DFND 2 2500 0 0 NEOLEUKIN THERAPEUTICS INC COM 64049K104 198 14000 SH DFND 2 14000 0 0 NETAPP INC COM 64110D104 2236 34366 SH DFND 1 34366 0 0 NETAPP INC COM 64110D104 924 14200 SH DFND 2 14200 0 0 NETAPP INC COM 64110D104 1 15 SH SOLE 15 0 0 NETEASE INC SPONSORED ADS 64110W102 6580 69078 SH DFND 1 69078 0 0 NETEASE INC SPONSORED ADS 64110W102 3107 32619 SH DFND 2 32619 0 0 NETFLIX INC COM 64110L106 72646 136479 SH DFND 1 136479 0 0 NETFLIX INC COM 64110L106 15037 28250 SH DFND 2 28250 0 0 NETFLIX INC COM 64110L106 15 29 SH SOLE 29 0 0 NETSCOUT SYS INC COM 64115T104 334 12240 SH DFND 1 12240 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 487 5216 SH DFND 1 5216 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 2252 24130 SH DFND 2 24130 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 0 5 SH SOLE 5 0 0 NEW JERSEY RES CORP COM 646025106 1161 32990 SH DFND 1 32990 0 0 NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581107 2901 17215 SH DFND 1 17215 0 0 NEW ORIENTAL ED & TECHNOLOGY SPON ADR 647581107 21311 126451 SH DFND 2 126451 0 0 NEW YORK CMNTY BANCORP INC COM 649445103 412 40153 SH DFND 1 40153 0 0 NEWELL BRANDS INC COM 651229106 789 37921 SH DFND 1 37921 0 0 NEWELL BRANDS INC COM 651229106 1 28 SH SOLE 28 0 0 NEWMONT CORP COM 651639106 21032 350354 SH DFND 1 350354 0 0 NEWMONT CORP COM 651639106 7944 132328 SH DFND 2 132328 0 0 NEWS CORP NEW CL A 65249B109 405 22705 SH DFND 1 22705 0 0 NEWS CORP NEW CL B 65249B208 7 405 SH DFND 1 405 0 0 NEXTERA ENERGY INC COM 65339F101 128509 1687653 SH DFND 1 1687653 0 0 NEXTERA ENERGY INC COM 65339F101 26134 343204 SH DFND 2 343204 0 0 NEXTERA ENERGY PARTNERS LP COM UNIT PART IN 65341B106 159 2400 SH DFND 1 2400 0 0 NGM BIOPHARMACEUTICALS INC COM 62921N105 654 21100 SH DFND 2 21100 0 0 NICE LTD SPONSORED ADR 653656108 2502 9000 SH DFND 1 9000 0 0 NICE LTD SPONSORED ADR 653656108 1946 7000 SH DFND 2 7000 0 0 NIELSEN HLDGS PLC SHS EUR G6518L108 88 4308 SH DFND 1 4308 0 0 NIELSEN HLDGS PLC SHS EUR G6518L108 11 527 SH SOLE 527 0 0 NIKE INC CL B 654106103 110364 776223 SH DFND 1 776223 0 0 NIKE INC CL B 654106103 19763 139000 SH DFND 2 139000 0 0 NIKE INC CL B 654106103 12 81 SH SOLE 81 0 0 NIO INC SPON ADS 62914V106 14590 312106 SH DFND 1 312106 0 0 NIO INC SPON ADS 62914V106 2356 50400 SH DFND 2 50400 0 0 NISOURCE INC COM 65473P105 1703 76073 SH DFND 1 76073 0 0 NISOURCE INC COM 65473P105 0 4 SH SOLE 4 0 0 NIU TECHNOLOGIES ADS 65481N100 8488 300000 SH DFND 1 300000 0 0 NKARTA INC COM 65487U108 674 10500 SH DFND 2 10500 0 0 NOAH HLDGS LTD SPON ADS CL A 65487X102 70 1583 SH DFND 1 1583 0 0 NORDSON CORP COM 655663102 757 3845 SH DFND 1 3845 0 0 NORDSON CORP COM 655663102 1 4 SH SOLE 4 0 0 NORFOLK SOUTHN CORP COM 655844108 15411 65936 SH DFND 1 65936 0 0 NORFOLK SOUTHN CORP COM 655844108 841 3600 SH DFND 2 3600 0 0 NORFOLK SOUTHN CORP COM 655844108 64 274 SH SOLE 274 0 0 NORTHERN TR CORP COM 665859104 3255 35515 SH DFND 1 35515 0 0 NORTHERN TR CORP COM 665859104 1 16 SH SOLE 16 0 0 NORTHROP GRUMMAN CORP COM 666807102 59032 195749 SH DFND 1 195749 0 0 NORTHROP GRUMMAN CORP COM 666807102 7841 26000 SH DFND 2 26000 0 0 NORTONLIFELOCK INC COM 668771108 2451 117883 SH DFND 1 117883 0 0 NORTONLIFELOCK INC COM 668771108 1 52 SH SOLE 52 0 0 NORWEGIAN CRUISE LINE HLDG L SHS G66721104 23 918 SH DFND 1 918 0 0 NOVANTA INC COM 67000B104 26668 227000 SH DFND 2 227000 0 0 NOVAVAX INC COM NEW 670002401 2388 20000 SH DFND 2 20000 0 0 NOVUS CAP CORP COM 67012U108 3002 200000 SH DFND 1 200000 0 0 NRG ENERGY INC COM NEW 629377508 1955 54800 SH DFND 1 54800 0 0 NUCOR CORP COM 670346105 5116 98558 SH DFND 1 98558 0 0 NUCOR CORP COM 670346105 716 13800 SH DFND 2 13800 0 0 NURIX THERAPEUTICS INC COM 67080M103 465 12400 SH DFND 2 12400 0 0 NUTRIEN LTD COM 67077M108 3157 67294 SH DFND 1 67294 0 0 NUTRIEN LTD COM 67077M108 2346 50000 SH DFND 2 50000 0 0 NVIDIA CORPORATION COM 67066G104 137966 264857 SH DFND 1 264857 0 0 NVIDIA CORPORATION COM 67066G104 98594 189273 SH DFND 2 189273 0 0 NVIDIA CORPORATION COM 67066G104 19 37 SH SOLE 37 0 0 NVR INC COM 62944T105 2600 629 SH DFND 1 629 0 0 NVR INC COM 62944T105 529 128 SH DFND 2 128 0 0 NXP SEMICONDUCTORS N V COM N6596X109 82004 525891 SH DFND 1 525891 0 0 NXP SEMICONDUCTORS N V COM N6596X109 5746 36850 SH DFND 2 36850 0 0 O- I GLASS INC COM 67098H104 727 62563 SH DFND 1 62563 0 0 OAK STR HEALTH INC COM 67181A107 843 14000 SH DFND 2 14000 0 0 OCCIDENTAL PETE CORP COM 674599105 1185 68430 SH DFND 1 68430 0 0 OCULAR THERAPEUTIX INC COM 67576A100 454 22900 SH DFND 2 22900 0 0 ODONATE THERAPEUTICS INC COM 676079106 248 14000 SH DFND 2 14000 0 0 OGE ENERGY CORP COM 670837103 762 24785 SH DFND 1 24785 0 0 OGE ENERGY CORP COM 670837103 3461 112552 SH DFND 2 112552 0 0 OGE ENERGY CORP COM 670837103 0 5 SH SOLE 5 0 0 OKTA INC CL A 679295105 3956 15000 SH DFND 1 15000 0 0 OLD DOMINION FREIGHT LINE IN COM 679580100 3384 17519 SH DFND 1 17519 0 0 OLD DOMINION FREIGHT LINE IN COM 679580100 3968 20545 SH DFND 2 20545 0 0 OLD DOMINION FREIGHT LINE IN COM 679580100 2 9 SH SOLE 9 0 0 OLD REP INTL CORP COM 680223104 364 18500 SH DFND 1 18500 0 0 OLD REP INTL CORP COM 680223104 840 42700 SH DFND 2 42700 0 0 OMEGA HEALTHCARE INVS INC COM 681936100 4501 120750 SH DFND 1 120750 0 0 OMEGA HEALTHCARE INVS INC COM 681936100 1 15 SH SOLE 15 0 0 OMEROS CORP COM 682143102 211 14900 SH DFND 2 14900 0 0 OMNICOM GROUP INC COM 681919106 3223 51218 SH DFND 1 51218 0 0 OMNICOM GROUP INC COM 681919106 7884 125270 SH DFND 2 125270 0 0 OMNICOM GROUP INC COM 681919106 1 19 SH SOLE 19 0 0 ON SEMICONDUCTOR CORP COM 682189105 2272 72252 SH DFND 1 72252 0 0 ON SEMICONDUCTOR CORP COM 682189105 1 20 SH SOLE 20 0 0 ONE GAS INC COM 68235P108 266 3510 SH DFND 1 3510 0 0 ONE GAS INC COM 68235P108 1253 16560 SH DFND 2 16560 0 0 ONECONNECT FINL TECHNOLOGY C SPONSORED ADS 68248T105 154 7544 SH DFND 1 7544 0 0 ONEMAIN HLDGS INC COM 68268W103 407 8800 SH DFND 1 8800 0 0 ONEMAIN HLDGS INC COM 68268W103 930 20100 SH DFND 2 20100 0 0 ONEOK INC NEW COM 682680103 1803 47537 SH DFND 1 47537 0 0 ONESPAN INC COM 68287N100 355 17200 SH DFND 1 17200 0 0 OPEN TEXT CORP COM 683715106 981 21695 SH DFND 1 21695 0 0 OPEN TEXT CORP COM 683715106 176 3900 SH DFND 2 3900 0 0 OPKO HEALTH INC COM 68375N103 886 214874 SH DFND 2 214874 0 0 ORACLE CORP COM 68389X105 57051 882199 SH DFND 1 882199 0 0 ORACLE CORP COM 68389X105 53291 824052 SH DFND 2 824052 0 0 OREILLY AUTOMOTIVE INC COM 67103H107 6810 15028 SH DFND 1 15028 0 0 OREILLY AUTOMOTIVE INC COM 67103H107 1777 3922 SH DFND 2 3922 0 0 OREILLY AUTOMOTIVE INC COM 67103H107 2 5 SH SOLE 5 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 408 10500 SH DFND 2 10500 0 0 ORMAT TECHNOLOGIES INC COM 686688102 6073 67164 SH DFND 1 67164 0 0 OSHKOSH CORP COM 688239201 713 8400 SH DFND 2 8400 0 0 OTIS WORLDWIDE CORP COM 68902V107 72453 1107095 SH DFND 1 1107095 0 0 OTIS WORLDWIDE CORP COM 68902V107 1447 22118 SH DFND 2 22118 0 0 OTIS WORLDWIDE CORP COM 68902V107 2 26 SH SOLE 26 0 0 OTTER TAIL CORP COM 689648103 783 18709 SH DFND 1 18709 0 0 OVERSTOCK COM INC DEL COM 690370101 200 3860 SH DFND 1 3860 0 0 OVINTIV INC COM 69047Q102 182 13000 SH DFND 2 13000 0 0 OWENS CORNING NEW COM 690742101 12305 162647 SH DFND 1 162647 0 0 OWENS CORNING NEW COM 690742101 1 7 SH SOLE 7 0 0 P T TELEKOMUNIKASI INDONESIA SPONSORED ADR 715684106 152 6440 SH DFND 1 6440 0 0 PACCAR INC COM 693718108 5561 65040 SH DFND 1 65040 0 0 PACCAR INC COM 693718108 15148 177175 SH DFND 2 177175 0 0 PACCAR INC COM 693718108 2 24 SH SOLE 24 0 0 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1674 64800 SH DFND 2 64800 0 0 PACIRA BIOSCIENCES INC COM 695127100 1430 24315 SH DFND 2 24315 0 0 PACKAGING CORP AMER COM 695156109 9949 73524 SH DFND 1 73524 0 0 PACKAGING CORP AMER COM 695156109 22955 169636 SH DFND 2 169636 0 0 PACKAGING CORP AMER COM 695156109 1 4 SH SOLE 4 0 0 PAE INC COM CL A 69290Y109 179 19227 SH DFND 1 19227 0 0 PALO ALTO NETWORKS INC COM 697435105 15064 42410 SH DFND 1 42410 0 0 PALO ALTO NETWORKS INC COM 697435105 2877 8100 SH DFND 2 8100 0 0 PALO ALTO NETWORKS INC COM 697435105 4 12 SH SOLE 12 0 0 PAN AMERN SILVER CORP COM 697900108 1092 32402 SH DFND 1 32402 0 0 PAN AMERN SILVER CORP COM 697900108 337 10000 SH DFND 2 10000 0 0 PANDION THERAPEUTICS INC COM 698340106 137 9000 SH DFND 2 9000 0 0 PARK HOTELS RESORTS INC COM 700517105 3566 210043 SH DFND 1 210043 0 0 PARKER- HANNIFIN CORP COM 701094104 6775 25433 SH DFND 1 25433 0 0 PARKER- HANNIFIN CORP COM 701094104 26639 100000 SH DFND 2 100000 0 0 PARKER- HANNIFIN CORP COM 701094104 2 9 SH SOLE 9 0 0 PARSLEY ENERGY INC CL A 701877102 282 20649 SH DFND 2 20649 0 0 PASSAGE BIO INC COM 702712100 380 14300 SH DFND 2 14300 0 0 PAYCHEX INC COM 704326107 13216 142160 SH DFND 1 142160 0 0 PAYCHEX INC COM 704326107 9145 98375 SH DFND 2 98375 0 0 PAYCHEX INC COM 704326107 2 22 SH SOLE 22 0 0 PAYCOM SOFTWARE INC COM 70432V102 4064 9079 SH DFND 1 9079 0 0 PAYCOM SOFTWARE INC COM 70432V102 972 2171 SH DFND 2 2171 0 0 PAYCOM SOFTWARE INC COM 70432V102 2 4 SH SOLE 4 0 0 PAYLOCITY HLDG CORP COM 70438V106 2096 10143 SH DFND 1 10143 0 0 PAYLOCITY HLDG CORP COM 70438V106 1095 5300 SH DFND 2 5300 0 0 PAYPAL HLDGS INC COM 70450Y103 151433 648037 SH DFND 1 648037 0 0 PAYPAL HLDGS INC COM 70450Y103 34070 145800 SH DFND 2 145800 0 0 PAYPAL HLDGS INC COM 70450Y103 18 78 SH SOLE 78 0 0 PDC ENERGY INC COM 69327R101 1412 70000 SH DFND 1 70000 0 0 PDL BIOPHARMA INC COM 69329Y104 133 50100 SH DFND 2 50100 0 0 PELOTON INTERACTIVE INC CL A COM 70614W100 2489 16328 SH DFND 1 16328 0 0 PEMBINA PIPELINE CORP COM 706327103 52304 2203042 SH DFND 1 2203042 0 0 PEMBINA PIPELINE CORP COM 706327103 859 36164 SH DFND 2 36164 0 0 PENTAIR PLC SHS G7S00T104 14612 284167 SH DFND 1 284167 0 0 PENTAIR PLC SHS G7S00T104 1 15 SH SOLE 15 0 0 PEOPLES UNITED FINANCIAL INC COM 712704105 156 12324 SH DFND 1 12324 0 0 PEOPLES UNITED FINANCIAL INC COM 712704105 8 668 SH SOLE 668 0 0 PEPSICO INC COM 713448108 268237 1805968 SH DFND 1 1805968 0 0 PEPSICO INC COM 713448108 53651 361214 SH DFND 2 361214 0 0 PEPSICO INC COM 713448108 14 97 SH SOLE 97 0 0 PERKINELMER INC COM 714046109 1050 7551 SH DFND 1 7551 0 0 PERKINELMER INC COM 714046109 1 7 SH SOLE 7 0 0 PERRIGO CO PLC SHS G97822103 526 11880 SH DFND 1 11880 0 0 PERSONALIS INC COM 71535D106 913 23800 SH DFND 2 23800 0 0 PETROCHINA CO LTD SPONSORED ADR 71646E100 61 2000 SH DFND 1 2000 0 0 PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408 136 12600 SH DFND 1 12600 0 0 PFIZER INC COM 717081103 167912 4513796 SH DFND 1 4513796 0 0 PFIZER INC COM 717081103 61443 1651714 SH DFND 2 1651714 0 0 PFIZER INC COM 717081103 13 359 SH SOLE 359 0 0 PG& E CORP COM 69331C108 721 61221 SH DFND 1 61221 0 0 PHILIP MORRIS INTL INC COM 718172109 173772 2103351 SH DFND 1 2103351 0 0 PHILIP MORRIS INTL INC COM 718172109 4323 52326 SH DFND 2 52326 0 0 PHILLIPS 66 COM 718546104 60191 879237 SH DFND 1 879237 0 0 PHILLIPS 66 COM 718546104 3471 50697 SH DFND 2 50697 0 0 PHILLIPS 66 COM 718546104 0 5 SH SOLE 5 0 0 PHYSICIANS RLTY TR COM 71943U104 103 5794 SH DFND 1 5794 0 0 PINDUODUO INC SPONSORED ADS 722304102 9699 58839 SH DFND 1 58839 0 0 PINDUODUO INC SPONSORED ADS 722304102 280 1700 SH DFND 2 1700 0 0 PINNACLE WEST CAP CORP COM 723484101 1431 18040 SH DFND 1 18040 0 0 PINTEREST INC CL A 72352L106 18468 268737 SH DFND 1 268737 0 0 PIONEER NAT RES CO COM 723787107 3012 27359 SH DFND 1 27359 0 0 PIONEER NAT RES CO COM 723787107 226 2053 SH DFND 2 2053 0 0 PLIANT THERAPEUTICS INC COM 729139105 294 12000 SH DFND 2 12000 0 0 PLUG POWER INC COM NEW 72919P202 19662 597500 SH DFND 1 597500 0 0 PLUG POWER INC COM NEW 72919P202 1366 41500 SH DFND 2 41500 0 0 PNC FINL SVCS GROUP INC COM 693475105 11711 81365 SH DFND 1 81365 0 0 PNC FINL SVCS GROUP INC COM 693475105 6 44 SH SOLE 44 0 0 PNM RES INC COM 69349H107 145 3000 SH DFND 1 3000 0 0 POLARIS INC COM 731068102 284 3000 SH DFND 1 3000 0 0 POLARIS INC COM 731068102 663 7000 SH DFND 2 7000 0 0 POOL CORP COM 73278L105 1803 4986 SH DFND 1 4986 0 0 POOL CORP COM 73278L105 2351 6500 SH DFND 2 6500 0 0 POSCO SPONSORED ADR 693483109 2018 32817 SH DFND 2 32817 0 0 POSEIDA THERAPEUTICS INC COM 73730P108 249 22000 SH DFND 2 22000 0 0 PPD INC COM 69355F102 212 5714 SH DFND 1 5714 0 0 PPG INDS INC COM 693506107 5047 34768 SH DFND 1 34768 0 0 PPG INDS INC COM 693506107 2 15 SH SOLE 15 0 0 PPL CORP COM 69351T106 3081 110759 SH DFND 1 110759 0 0 PPL CORP COM 69351T106 0 5 SH SOLE 5 0 0 PRA HEALTH SCIENCES INC COM 69354M108 4738 39100 SH DFND 2 39100 0 0 PRECIGEN INC COM 74017N105 458 46500 SH DFND 2 46500 0 0 PREMIER INC CL A 74051N102 3256 93846 SH DFND 1 93846 0 0 PRICE T ROWE GROUP INC COM 74144T108 20832 141122 SH DFND 1 141122 0 0 PRICE T ROWE GROUP INC COM 74144T108 17527 118729 SH DFND 2 118729 0 0 PRICE T ROWE GROUP INC COM 74144T108 5 31 SH SOLE 31 0 0 PRICESMART INC COM 741511109 346 3791 SH DFND 1 3791 0 0 PRIMERICA INC COM 74164M108 194 1460 SH DFND 1 1460 0 0 PRINCIPAL FINANCIAL GROUP IN COM 74251V102 2809 58547 SH DFND 1 58547 0 0 PRINCIPAL FINANCIAL GROUP IN COM 74251V102 777 16200 SH DFND 2 16200 0 0 PRINCIPAL FINANCIAL GROUP IN COM 74251V102 1 20 SH SOLE 20 0 0 PROCTER AND GAMBLE CO COM 742718109 336746 2422085 SH DFND 1 2422085 0 0 PROCTER AND GAMBLE CO COM 742718109 78177 562296 SH DFND 2 562296 0 0 PROCTER AND GAMBLE CO COM 742718109 19 139 SH SOLE 139 0 0 PROGRESS SOFTWARE CORP COM 743312100 770 17205 SH DFND 1 17205 0 0 PROGRESS SOFTWARE CORP COM 743312100 303 6767 SH DFND 2 6767 0 0 PROGRESSIVE CORP COM 743315103 90444 924817 SH DFND 1 924817 0 0 PROGRESSIVE CORP COM 743315103 4375 44734 SH DFND 2 44734 0 0 PROGRESSIVE CORP COM 743315103 4 43 SH SOLE 43 0 0 PROGYNY INC COM 74340E103 2435 57500 SH DFND 1 57500 0 0 PROGYNY INC COM 74340E103 318 7500 SH DFND 2 7500 0 0 PROLOGIS INC. COM 74340W103 56807 584539 SH DFND 1 584539 0 0 PROLOGIS INC. COM 74340W103 8086 83200 SH DFND 2 83200 0 0 PROLOGIS INC. COM 74340W103 5 52 SH SOLE 52 0 0 PROOFPOINT INC COM 743424103 368 2800 SH DFND 1 2800 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 300 14000 SH DFND 2 14000 0 0 PROTHENA CORP PLC SHS G72800108 150 12350 SH DFND 2 12350 0 0 PROVENTION BIO INC COM 74374N102 342 20000 SH DFND 2 20000 0 0 PRUDENTIAL FINL INC COM 744320102 7372 96663 SH DFND 1 96663 0 0 PRUDENTIAL FINL INC COM 744320102 722 9471 SH DFND 2 9471 0 0 PRUDENTIAL FINL INC COM 744320102 2 32 SH SOLE 32 0 0 PTC INC COM 69370C100 3409 28888 SH DFND 1 28888 0 0 PTC INC COM 69370C100 35104 297500 SH DFND 2 297500 0 0 PTC INC COM 69370C100 1 7 SH SOLE 7 0 0 PTC THERAPEUTICS INC COM 69366J200 1401 21900 SH DFND 2 21900 0 0 PUBLIC STORAGE COM 74460D109 13014 57438 SH DFND 1 57438 0 0 PUBLIC STORAGE COM 74460D109 7131 31474 SH DFND 2 31474 0 0 PUBLIC STORAGE COM 74460D109 2 11 SH SOLE 11 0 0 PUBLIC SVC ENTERPRISE GRP IN COM 744573106 11230 197604 SH DFND 1 197604 0 0 PUBLIC SVC ENTERPRISE GRP IN COM 744573106 8309 146199 SH DFND 2 146199 0 0 PULTE GROUP INC COM 745867101 2295 51825 SH DFND 1 51825 0 0 PULTE GROUP INC COM 745867101 633 14300 SH DFND 2 14300 0 0 PULTE GROUP INC COM 745867101 1 20 SH SOLE 20 0 0 PUMA BIOTECHNOLOGY INC COM 74587V107 80 8000 SH DFND 2 8000 0 0 PVH CORPORATION COM 693656100 22 236 SH DFND 1 236 0 0 QIAGEN NV SHS NEW N72482123 103149 1952748 SH DFND 1 1952748 0 0 QIAGEN NV SHS NEW N72482123 23345 441957 SH DFND 2 441957 0 0 QORVO INC COM 74736K101 3092 18481 SH DFND 1 18481 0 0 QORVO INC COM 74736K101 205 1223 SH DFND 2 1223 0 0 QORVO INC COM 74736K101 2 10 SH SOLE 10 0 0 QTS RLTY TR INC COM CL A 74736A103 1283 21415 SH DFND 1 21415 0 0 QUALCOMM INC COM 747525103 88132 593074 SH DFND 1 593074 0 0 QUALCOMM INC COM 747525103 58150 391311 SH DFND 2 391311 0 0 QUALCOMM INC COM 747525103 15 101 SH SOLE 101 0 0 QUALYS INC COM 74758T303 1006 8590 SH DFND 1 8590 0 0 QUANTA SVCS INC COM 74762E102 15721 222250 SH DFND 1 222250 0 0 QUANTA SVCS INC COM 74762E102 3133 44300 SH DFND 2 44300 0 0 QUEST DIAGNOSTICS INC COM 74834L100 11148 93910 SH DFND 1 93910 0 0 QUEST DIAGNOSTICS INC COM 74834L100 21752 183235 SH DFND 2 183235 0 0 QUEST DIAGNOSTICS INC COM 74834L100 1 9 SH SOLE 9 0 0 QURATE RETAIL INC COM SER A 74915M100 477 44800 SH DFND 1 44800 0 0 QURATE RETAIL INC COM SER A 74915M100 1117 104930 SH DFND 2 104930 0 0 RADIUS HEALTH INC COM NEW 750469207 273 15200 SH DFND 2 15200 0 0 RADWARE LTD ORD M81873107 359 13150 SH DFND 1 13150 0 0 RALPH LAUREN CORP CL A 751212101 16 160 SH DFND 1 160 0 0 RALPH LAUREN CORP CL A 751212101 7 69 SH SOLE 69 0 0 RAPID7 INC COM 753422104 621 6970 SH DFND 1 6970 0 0 RAPT THERAPEUTICS INC COM 75382E109 157 8000 SH DFND 2 8000 0 0 RAYMOND JAMES FINL INC COM 754730109 1140 12190 SH DFND 1 12190 0 0 RAYMOND JAMES FINL INC COM 754730109 1 12 SH SOLE 12 0 0 RAYONIER INC COM 754907103 113 3942 SH DFND 1 3942 0 0 REALTY INCOME CORP COM 756109104 2064 33557 SH DFND 1 33557 0 0 REALTY INCOME CORP COM 756109104 0 7 SH SOLE 7 0 0 REATA PHARMACEUTICALS INC CL A 75615P103 1886 14740 SH DFND 2 14740 0 0 REDFIN CORP COM 75737F108 1120 15561 SH DFND 1 15561 0 0 REGENCY CTRS CORP COM 758849103 715 15974 SH DFND 1 15974 0 0 REGENCY CTRS CORP COM 758849103 0 9 SH SOLE 9 0 0 REGENERON PHARMACEUTICALS COM 75886F107 7830 16113 SH DFND 1 16113 0 0 REGENERON PHARMACEUTICALS COM 75886F107 21466 44172 SH DFND 2 44172 0 0 REGENXBIO INC COM 75901B107 2471 53300 SH DFND 2 53300 0 0 REGIONS FINANCIAL CORP NEW COM 7591EP100 2428 154208 SH DFND 1 154208 0 0 REGIONS FINANCIAL CORP NEW COM 7591EP100 1 66 SH SOLE 66 0 0 REINSURANCE GRP OF AMERICA I COM NEW 759351604 865 7562 SH DFND 1 7562 0 0 RELAY THERAPEUTICS INC COM 75943R102 1132 26700 SH DFND 2 26700 0 0 RELIANCE STEEL & ALUMINUM CO COM 759509102 2005 16974 SH DFND 1 16974 0 0 RELIANCE STEEL & ALUMINUM CO COM 759509102 1916 16223 SH DFND 2 16223 0 0 RELMADA THERAPEUTICS INC COM 75955J402 156 5000 SH DFND 2 5000 0 0 RENAISSANCERE HLDGS LTD COM G7496G103 635 3912 SH DFND 1 3912 0 0 REPARE THERAPEUTICS INC COM 760273102 440 12900 SH DFND 2 12900 0 0 REPLIMUNE GROUP INC COM 76029N106 633 15700 SH DFND 2 15700 0 0 REPUBLIC SVCS INC COM 760759100 9751 102276 SH DFND 1 102276 0 0 REPUBLIC SVCS INC COM 760759100 18822 197423 SH DFND 2 197423 0 0 REPUBLIC SVCS INC COM 760759100 1 10 SH SOLE 10 0 0 RESMED INC COM 761152107 4270 19947 SH DFND 1 19947 0 0 RESMED INC COM 761152107 613 2864 SH DFND 2 2864 0 0 RESMED INC COM 761152107 2 10 SH SOLE 10 0 0 RESTAURANT BRANDS INTL INC COM 76131D103 812 13444 SH DFND 1 13444 0 0 RESTAURANT BRANDS INTL INC COM 76131D103 1 14 SH SOLE 14 0 0 RETAIL PPTYS AMER INC CL A 76131V202 692 80055 SH DFND 1 80055 0 0 REVANCE THERAPEUTICS INC COM 761330109 1708 63100 SH DFND 2 63100 0 0 REVOLUTION MEDICINES INC COM 76155X100 842 21000 SH DFND 2 21000 0 0 REXFORD INDL RLTY INC COM 76169C100 2549 52853 SH DFND 1 52853 0 0 REXNORD CORP COM 76169B102 3178 82265 SH DFND 1 82265 0 0 RHYTHM PHARMACEUTICALS INC COM 76243J105 357 12000 SH DFND 2 12000 0 0 RIGEL PHARMACEUTICALS INC COM NEW 766559603 172 49600 SH DFND 2 49600 0 0 RINGCENTRAL INC CL A 76680R206 3028 7941 SH DFND 1 7941 0 0 RIO TINTO PLC SPONSORED ADR 767204100 227 3000 SH DFND 1 3000 0 0 RIO TINTO PLC SPONSORED ADR 767204100 840 11100 SH DFND 2 11100 0 0 RITCHIE BROS AUCTIONEERS COM 767744105 401 5766 SH DFND 1 5766 0 0 ROBERT HALF INTL INC COM 770323103 698 11233 SH DFND 1 11233 0 0 ROBERT HALF INTL INC COM 770323103 1 9 SH SOLE 9 0 0 ROCKET PHARMACEUTICALS INC COM 77313F106 2607 47300 SH DFND 2 47300 0 0 ROCKWELL AUTOMATION INC COM 773903109 12965 52798 SH DFND 1 52798 0 0 ROCKWELL AUTOMATION INC COM 773903109 51238 208655 SH DFND 2 208655 0 0 ROCKWELL AUTOMATION INC COM 773903109 2 8 SH SOLE 8 0 0 ROGERS COMMUNICATIONS INC CL B 775109200 15287 327034 SH DFND 1 327034 0 0 ROGERS COMMUNICATIONS INC CL B 775109200 29693 635200 SH DFND 2 635200 0 0 ROKU INC COM CL A 77543R102 3347 9777 SH DFND 1 9777 0 0 ROLLINS INC COM 775711104 772 20386 SH DFND 1 20386 0 0 ROLLINS INC COM 775711104 1 15 SH SOLE 15 0 0 ROPER TECHNOLOGIES INC COM 776696106 25841 61783 SH DFND 1 61783 0 0 ROPER TECHNOLOGIES INC COM 776696106 7147 17089 SH DFND 2 17089 0 0 ROPER TECHNOLOGIES INC COM 776696106 4 10 SH SOLE 10 0 0 ROSS STORES INC COM 778296103 25024 203765 SH DFND 1 203765 0 0 ROSS STORES INC COM 778296103 7196 58600 SH DFND 2 58600 0 0 ROSS STORES INC COM 778296103 4 30 SH SOLE 30 0 0 ROTH CH ACQUISITION I CO COM 778675108 849 50000 SH DFND 1 50000 0 0 ROYAL BK CDA COM 780087102 18526 225890 SH DFND 1 225890 0 0 ROYAL BK CDA COM 780087102 16660 203140 SH DFND 2 203140 0 0 ROYAL CARIBBEAN GROUP COM V7780T103 2837 38827 SH DFND 1 38827 0 0 ROYAL CARIBBEAN GROUP COM V7780T103 1067 14600 SH DFND 2 14600 0 0 ROYAL GOLD INC COM 780287108 923 8400 SH DFND 1 8400 0 0 ROYAL GOLD INC COM 780287108 44 400 SH DFND 2 400 0 0 ROYALTY PHARMA PLC SHS CLASS A G7709Q104 411 8428 SH DFND 1 8428 0 0 ROYALTY PHARMA PLC SHS CLASS A G7709Q104 3654 75000 SH DFND 2 75000 0 0 RPM INTL INC COM 749685103 940 10540 SH DFND 1 10540 0 0 RPM INTL INC COM 749685103 1 6 SH SOLE 6 0 0 RUBIUS THERAPEUTICS INC COM 78116T103 208 28200 SH DFND 2 28200 0 0 S& P GLOBAL INC COM 78409V104 21891 68220 SH DFND 1 68220 0 0 S& P GLOBAL INC COM 78409V104 7412 23100 SH DFND 2 23100 0 0 S& P GLOBAL INC COM 78409V104 7 22 SH SOLE 22 0 0 SABRA HEALTH CARE REIT INC COM 78573L106 1702 98057 SH DFND 1 98057 0 0 SAGE THERAPEUTICS INC COM 78667J108 1699 19720 SH DFND 2 19720 0 0 SAILPOINT TECHNOLOGIES HLDGS COM 78781P105 619 11800 SH DFND 1 11800 0 0 SALESFORCE COM INC COM 79466L302 101168 451918 SH DFND 1 451918 0 0 SALESFORCE COM INC COM 79466L302 12525 55948 SH DFND 2 55948 0 0 SANGAMO THERAPEUTICS INC COM 800677106 1186 67900 SH DFND 2 67900 0 0 SANMINA CORPORATION COM 801056102 319 10300 SH DFND 1 10300 0 0 SANMINA CORPORATION COM 801056102 738 23800 SH DFND 2 23800 0 0 SANOFI SPONSORED ADR 80105N105 4112 85700 SH DFND 2 85700 0 0 SAREPTA THERAPEUTICS INC COM 803607100 822 4798 SH DFND 1 4798 0 0 SAREPTA THERAPEUTICS INC COM 803607100 5597 32660 SH DFND 2 32660 0 0 SAREPTA THERAPEUTICS INC COM 803607100 1 4 SH SOLE 4 0 0 SBA COMMUNICATIONS CORP NEW CL A 78410G104 4012 14638 SH DFND 1 14638 0 0 SBA COMMUNICATIONS CORP NEW CL A 78410G104 2 8 SH SOLE 8 0 0 SCHLUMBERGER LTD COM 806857108 7334 345629 SH DFND 1 345629 0 0 SCHLUMBERGER LTD COM 806857108 1140 53702 SH DFND 2 53702 0 0 SCHLUMBERGER LTD COM 806857108 0 17 SH SOLE 17 0 0 SCHOLAR ROCK HLDG CORP COM 80706P103 804 17100 SH DFND 2 17100 0 0 SCHWAB CHARLES CORP COM 808513105 10499 199731 SH DFND 1 199731 0 0 SCIENCE APPLICATIONS INTL CO COM 808625107 777 8200 SH DFND 2 8200 0 0 SCOTTS MIRACLE GRO CO CL A 810186106 507 2585 SH DFND 1 2585 0 0 SEA LTD SPONSORD ADS 81141R100 1309 6845 SH DFND 1 6845 0 0 SEA LTD SPONSORD ADS 81141R100 4424 23127 SH DFND 2 23127 0 0 SEAGATE TECHNOLOGY PLC SHS G7945M107 8855 146687 SH DFND 1 146687 0 0 SEAGATE TECHNOLOGY PLC SHS G7945M107 29397 487006 SH DFND 2 487006 0 0 SEAGATE TECHNOLOGY PLC SHS G7945M107 1 15 SH SOLE 15 0 0 SEAGEN INC COM 81181C104 4483 24161 SH DFND 1 24161 0 0 SEAGEN INC COM 81181C104 12336 66480 SH DFND 2 66480 0 0 SEAGEN INC COM 81181C104 1 7 SH SOLE 7 0 0 SEALED AIR CORP NEW COM 81211K100 1871 41551 SH DFND 1 41551 0 0 SEALED AIR CORP NEW COM 81211K100 0 9 SH SOLE 9 0 0 SECUREWORKS CORP CL A 81374A105 259 18665 SH DFND 1 18665 0 0 SEI INVTS CO COM 784117103 797 14151 SH DFND 1 14151 0 0 SEI INVTS CO COM 784117103 1 14 SH SOLE 14 0 0 SEMPRA ENERGY COM 816851109 82324 656095 SH DFND 1 656095 0 0 SEMPRA ENERGY COM 816851109 2723 21700 SH DFND 2 21700 0 0 SEMPRA ENERGY COM 816851109 1 5 SH SOLE 5 0 0 SENSATA TECHNOLOGIES HLDG PL SHS G8060N102 646 12563 SH DFND 1 12563 0 0 SERVICENOW INC COM 81762P102 39273 71912 SH DFND 1 71912 0 0 SERVICENOW INC COM 81762P102 61357 112350 SH DFND 2 112350 0 0 SHAW COMMUNICATIONS INC CL B CONV 82028K200 4681 264326 SH DFND 1 264326 0 0 SHAW COMMUNICATIONS INC CL B CONV 82028K200 9019 509300 SH DFND 2 509300 0 0 SHERWIN WILLIAMS CO COM 824348106 10655 14574 SH DFND 1 14574 0 0 SHERWIN WILLIAMS CO COM 824348106 428 586 SH DFND 2 586 0 0 SHERWIN WILLIAMS CO COM 824348106 5 7 SH SOLE 7 0 0 SHOPIFY INC CL A 82509L107 29358 24855 SH DFND 1 24855 0 0 SHOPIFY INC CL A 82509L107 8138 6890 SH DFND 2 6890 0 0 SHOPIFY INC CL A 82509L107 1 1 SH SOLE 1 0 0 SIBANYE STILLWATER LTD SPONSORED ADR 82575P107 862 55190 SH DFND 1 55190 0 0 SIGNATURE BK NEW YORK N Y COM 82669G104 419 3100 SH DFND 1 3100 0 0 SIGNATURE BK NEW YORK N Y COM 82669G104 961 7100 SH DFND 2 7100 0 0 SIGNATURE BK NEW YORK N Y COM 82669G104 11 81 SH SOLE 81 0 0 SILGAN HOLDINGS INC COM 827048109 2472 67421 SH DFND 1 67421 0 0 SILGAN HOLDINGS INC COM 827048109 816 22265 SH DFND 2 22265 0 0 SIMON PPTY GROUP INC NEW COM 828806109 15966 191459 SH DFND 1 191459 0 0 SIMON PPTY GROUP INC NEW COM 828806109 2 23 SH SOLE 23 0 0 SIMPSON MANUFACTURING CO INC COM 829073105 224 2458 SH DFND 1 2458 0 0 SINA CORP ORD G81477104 225 5433 SH DFND 1 5433 0 0 SIRIUS XM HOLDINGS INC COM 82968B103 4911 765860 SH DFND 1 765860 0 0 SIRIUS XM HOLDINGS INC COM 82968B103 136 21222 SH DFND 2 21222 0 0 SIRIUS XM HOLDINGS INC COM 82968B103 1 105 SH SOLE 105 0 0 SITE CTRS CORP COM 82981J109 820 82776 SH DFND 1 82776 0 0 SK TELECOM LTD SPONSORED ADR 78440P108 1819 74290 SH DFND 1 74290 0 0 SKYWORKS SOLUTIONS INC COM 83088M102 5437 35902 SH DFND 1 35902 0 0 SKYWORKS SOLUTIONS INC COM 83088M102 4434 29280 SH DFND 2 29280 0 0 SKYWORKS SOLUTIONS INC COM 83088M102 2 16 SH SOLE 16 0 0 SL GREEN RLTY CORP COM 78440X101 5086 87217 SH DFND 1 87217 0 0 SL GREEN RLTY CORP COM 78440X101 29 500 SH DFND 2 500 0 0 SLACK TECHNOLOGIES INC COM CL A 83088V102 991 23619 SH DFND 1 23619 0 0 SMITH A O CORP COM 831865209 759 13957 SH DFND 1 13957 0 0 SMITH A O CORP COM 831865209 212 3895 SH DFND 2 3895 0 0 SMITH A O CORP COM 831865209 1 10 SH SOLE 10 0 0 SMUCKER J M CO COM NEW 832696405 5106 44475 SH DFND 1 44475 0 0 SMUCKER J M CO COM NEW 832696405 14374 125200 SH DFND 2 125200 0 0 SMUCKER J M CO COM NEW 832696405 1 6 SH SOLE 6 0 0 SNAP INC CL A 83304A106 10976 212235 SH DFND 1 212235 0 0 SNAP INC CL A 83304A106 1 14 SH SOLE 14 0 0 SNAP ON INC COM 833034101 1395 8277 SH DFND 1 8277 0 0 SNAP ON INC COM 833034101 539 3197 SH DFND 2 3197 0 0 SNAP ON INC COM 833034101 1 3 SH SOLE 3 0 0 SNOWFLAKE INC CL A 833445109 3946 12935 SH DFND 1 12935 0 0 SNOWFLAKE INC CL A 833445109 80815 264900 SH DFND 2 264900 0 0 SOCIEDAD QUIMICA Y MINERA DE SPON ADR SER B 833635105 302 6200 SH DFND 2 6200 0 0 SOLAREDGE TECHNOLOGIES INC COM 83417M104 12482 40082 SH DFND 1 40082 0 0 SONOCO PRODS CO COM 835495102 633 10640 SH DFND 1 10640 0 0 SONOCO PRODS CO COM 835495102 58 979 SH DFND 2 979 0 0 SOTERA HEALTH CO COM 83601L102 543 19200 SH DFND 1 19200 0 0 SOTERA HEALTH CO COM 83601L102 1132 40000 SH DFND 2 40000 0 0 SOUTH JERSEY INDS INC COM 838518108 532 25011 SH DFND 1 25011 0 0 SOUTHERN CO COM 842587107 7565 125754 SH DFND 1 125754 0 0 SOUTHERN CO COM 842587107 5020 83441 SH DFND 2 83441 0 0 SOUTHERN COPPER CORP COM 84265V105 386 6000 SH DFND 2 6000 0 0 SOUTHWEST AIRLS CO COM 844741108 8223 178048 SH DFND 1 178048 0 0 SOUTHWEST AIRLS CO COM 844741108 2148 46500 SH DFND 2 46500 0 0 SOUTHWEST AIRLS CO COM 844741108 0 4 SH SOLE 4 0 0 SOUTHWEST GAS HOLDINGS INC COM 844895102 236 3903 SH DFND 1 3903 0 0 SOUTHWEST GAS HOLDINGS INC COM 844895102 634 10470 SH DFND 2 10470 0 0 SPECTRUM PHARMACEUTICALS INC COM 84763A108 146 42800 SH DFND 2 42800 0 0 SPERO THERAPEUTICS INC COM 84833T103 171 8500 SH DFND 2 8500 0 0 SPIRIT RLTY CAP INC NEW COM NEW 84860W300 4196 104355 SH DFND 1 104355 0 0 SPLUNK INC COM 848637104 4314 25029 SH DFND 1 25029 0 0 SPLUNK INC COM 848637104 1853 10750 SH DFND 2 10750 0 0 SPLUNK INC COM 848637104 1 3 SH SOLE 3 0 0 SPOTIFY TECHNOLOGY S A SHS L8681T102 1520 4761 SH DFND 1 4761 0 0 SPRINGWORKS THERAPEUTICS INC COM 85205L107 1109 15250 SH DFND 2 15250 0 0 SPROUTS FMRS MKT INC COM 85208M102 1209 59567 SH DFND 1 59567 0 0 SPX CORP COM 784635104 2349 44000 SH DFND 1 44000 0 0 SPX CORP COM 784635104 13401 251000 SH DFND 2 251000 0 0 SQUARE INC CL A 852234103 17766 82161 SH DFND 1 82161 0 0 SQUARE INC CL A 852234103 3373 15600 SH DFND 2 15600 0 0 SQUARE INC CL A 852234103 0 2 SH SOLE 2 0 0 SS& C TECHNOLOGIES HLDGS INC COM 78467J100 1321 18325 SH DFND 1 18325 0 0 SS& C TECHNOLOGIES HLDGS INC COM 78467J100 1 14 SH SOLE 14 0 0 SSR MNG INC COM 784730103 53 2651 SH DFND 1 2651 0 0 SSR MNG INC COM 784730103 238 12000 SH DFND 2 12000 0 0 ST JOE CO COM 790148100 275 6450 SH DFND 1 6450 0 0 STANDARD MTR PRODS INC COM 853666105 154 3797 SH DFND 1 3797 0 0 STANLEY BLACK & DECKER INC COM 854502101 5481 31291 SH DFND 1 31291 0 0 STANLEY BLACK & DECKER INC COM 854502101 1 3 SH SOLE 3 0 0 STANTEC INC COM 85472N109 185 5700 SH DFND 2 5700 0 0 STARBUCKS CORP COM 855244109 19817 186796 SH DFND 1 186796 0 0 STARBUCKS CORP COM 855244109 11171 105300 SH DFND 2 105300 0 0 STARBUCKS CORP COM 855244109 9 86 SH SOLE 86 0 0 STARWOOD PPTY TR INC COM 85571B105 128 6659 SH DFND 1 6659 0 0 STATE STR CORP COM 857477103 6092 84649 SH DFND 1 84649 0 0 STATE STR CORP COM 857477103 2 29 SH SOLE 29 0 0 STEEL DYNAMICS INC COM 858119100 3229 89280 SH DFND 1 89280 0 0 STEEL DYNAMICS INC COM 858119100 770 21300 SH DFND 2 21300 0 0 STEPAN CO COM 858586100 231 1967 SH DFND 1 1967 0 0 STEPAN CO COM 858586100 744 6334 SH DFND 2 6334 0 0 STERICYCLE INC COM 858912108 830 12047 SH DFND 1 12047 0 0 STERIS PLC SHS USD G8473T100 3172 17075 SH DFND 1 17075 0 0 STERIS PLC SHS USD G8473T100 5059 27237 SH DFND 2 27237 0 0 STERIS PLC SHS USD G8473T100 1 5 SH SOLE 5 0 0 STOKE THERAPEUTICS INC COM 86150R107 523 8900 SH DFND 2 8900 0 0 STORE CAP CORP COM 862121100 2311 67079 SH DFND 1 67079 0 0 STRATEGIC ED INC COM 86272C103 557 6000 SH DFND 2 6000 0 0 STRIDE INC COM 86333M108 545 26000 SH DFND 2 26000 0 0 STRYKER CORPORATION COM 863667101 18348 76108 SH DFND 1 76108 0 0 STRYKER CORPORATION COM 863667101 50461 209310 SH DFND 2 209310 0 0 STRYKER CORPORATION COM 863667101 5 22 SH SOLE 22 0 0 SUN CMNTYS INC COM 866674104 6605 44743 SH DFND 1 44743 0 0 SUN CMNTYS INC COM 866674104 280 1900 SH DFND 2 1900 0 0 SUN LIFE FINANCIAL INC. COM 866796105 4511 102997 SH DFND 1 102997 0 0 SUN LIFE FINANCIAL INC. COM 866796105 8194 187100 SH DFND 2 187100 0 0 SUNCOR ENERGY INC NEW COM 867224107 43890 2562771 SH DFND 1 2562771 0 0 SUNCOR ENERGY INC NEW COM 867224107 1661 97000 SH DFND 2 97000 0 0 SUNOPTA INC COM 8676EP108 2247 200000 SH DFND 1 200000 0 0 SUNRUN INC COM 86771W105 577 9048 SH DFND 1 9048 0 0 SUPERNUS PHARMACEUTICALS INC COM 868459108 490 19700 SH DFND 2 19700 0 0 SUTRO BIOPHARMA INC COM 869367102 233 11000 SH DFND 2 11000 0 0 SVB FINANCIAL GROUP COM 78486Q101 3583 9518 SH DFND 1 9518 0 0 SVB FINANCIAL GROUP COM 78486Q101 838 2225 SH DFND 2 2225 0 0 SVB FINANCIAL GROUP COM 78486Q101 1 3 SH SOLE 3 0 0 SWITCHBACK ENERGY ACQUISTN C COM CL A 87105M102 6697 165000 SH DFND 1 165000 0 0 SYNCHRONY FINANCIAL COM 87165B103 13661 403317 SH DFND 1 403317 0 0 SYNCHRONY FINANCIAL COM 87165B103 3 95 SH SOLE 95 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 575 25000 SH DFND 2 25000 0 0 SYNEOS HEALTH INC CL A 87166B102 2302 34650 SH DFND 2 34650 0 0 SYNNEX CORP COM 87162W100 169 2100 SH DFND 1 2100 0 0 SYNNEX CORP COM 87162W100 395 4900 SH DFND 2 4900 0 0 SYNOPSYS INC COM 871607107 11817 46642 SH DFND 1 46642 0 0 SYNOPSYS INC COM 871607107 4161 16423 SH DFND 2 16423 0 0 SYNOPSYS INC COM 871607107 2 8 SH SOLE 8 0 0 SYSCO CORP COM 871829107 6532 89655 SH DFND 1 89655 0 0 SYSCO CORP COM 871829107 2 34 SH SOLE 34 0 0 T- MOBILE US INC COM 872590104 56393 419880 SH DFND 1 419880 0 0 T- MOBILE US INC COM 872590104 8604 64060 SH DFND 2 64060 0 0 T- MOBILE US INC COM 872590104 4 31 SH SOLE 31 0 0 TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 6343 58927 SH DFND 1 58927 0 0 TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 5325 49467 SH DFND 2 49467 0 0 TAKE- TWO INTERACTIVE SOFTWAR COM 874054109 17137 83190 SH DFND 1 83190 0 0 TAKE- TWO INTERACTIVE SOFTWAR COM 874054109 21092 102388 SH DFND 2 102388 0 0 TAKE- TWO INTERACTIVE SOFTWAR COM 874054109 1 7 SH SOLE 7 0 0 TAL EDUCATION GROUP SPONSORED ADS 874080104 1535 22090 SH DFND 1 22090 0 0 TAL EDUCATION GROUP SPONSORED ADS 874080104 231 3320 SH DFND 2 3320 0 0 TAPESTRY INC COM 876030107 491 16320 SH DFND 1 16320 0 0 TAPESTRY INC COM 876030107 1155 38400 SH DFND 2 38400 0 0 TARGET CORP COM 87612E106 131162 745613 SH DFND 1 745613 0 0 TARGET CORP COM 87612E106 2809 15966 SH DFND 2 15966 0 0 TARGET CORP COM 87612E106 8 44 SH SOLE 44 0 0 TARO PHARMACEUTICAL INDS LTD SHS M8737E108 541 7459 SH DFND 1 7459 0 0 TAUBMAN CTRS INC COM 876664103 64 1500 SH DFND 1 1500 0 0 TC ENERGY CORP COM 87807B107 2930 72614 SH DFND 1 72614 0 0 TC ENERGY CORP COM 87807B107 2923 72455 SH DFND 2 72455 0 0 TCR2 THERAPEUTICS INC COM 87808K106 397 13000 SH DFND 2 13000 0 0 TE CONNECTIVITY LTD REG SHS H84989104 77362 652950 SH DFND 1 652950 0 0 TE CONNECTIVITY LTD REG SHS H84989104 3 29 SH SOLE 29 0 0 TECHNIPFMC PLC COM G87110105 2130 229676 SH DFND 1 229676 0 0 TECHNIPFMC PLC COM G87110105 3884 418788 SH DFND 2 418788 0 0 TECHTARGET INC COM 87874R100 296 5208 SH DFND 1 5208 0 0 TECK RESOURCES LTD CL B 878742204 635 36687 SH DFND 1 36687 0 0 TECK RESOURCES LTD CL B 878742204 7470 431900 SH DFND 2 431900 0 0 TELADOC HEALTH INC COM 87918A105 4882 24209 SH DFND 1 24209 0 0 TELADOC HEALTH INC COM 87918A105 2264 11230 SH DFND 2 11230 0 0 TELEDYNE TECHNOLOGIES INC COM 879360105 1206 3163 SH DFND 1 3163 0 0 TELEDYNE TECHNOLOGIES INC COM 879360105 2 5 SH SOLE 5 0 0 TELEFLEX INCORPORATED COM 879369106 3747 9287 SH DFND 1 9287 0 0 TELEFLEX INCORPORATED COM 879369106 2421 6000 SH DFND 2 6000 0 0 TELEFLEX INCORPORATED COM 879369106 1 3 SH SOLE 3 0 0 TELEFONICA BRASIL SA NEW ADR 87936R205 17 2000 SH DFND 1 2000 0 0 TELUS CORPORATION COM 87971M103 19322 951926 SH DFND 1 951926 0 0 TELUS CORPORATION COM 87971M103 18722 922400 SH DFND 2 922400 0 0 TENABLE HLDGS INC COM 88025T102 618 12250 SH DFND 1 12250 0 0 TENCENT MUSIC ENTMT GROUP SPON ADS 88034P109 330 17301 SH DFND 1 17301 0 0 TENCENT MUSIC ENTMT GROUP SPON ADS 88034P109 128 6700 SH DFND 2 6700 0 0 TERADYNE INC COM 880770102 4610 38643 SH DFND 1 38643 0 0 TERADYNE INC COM 880770102 1221 10234 SH DFND 2 10234 0 0 TERADYNE INC COM 880770102 2 14 SH SOLE 14 0 0 TERMINIX GLOBAL HOLDINGS INC COM 88087E100 984 20000 SH DFND 1 20000 0 0 TERRENO RLTY CORP COM 88146M101 104 1853 SH DFND 1 1853 0 0 TESLA INC COM 88160R101 123693 183555 SH DFND 1 183555 0 0 TESLA INC COM 88160R101 17453 25900 SH DFND 2 25900 0 0 TETRA TECH INC NEW COM 88162G103 6235 54500 SH DFND 1 54500 0 0 TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 223 23017 SH DFND 1 23017 0 0 TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 1 73 SH SOLE 73 0 0 TEXAS INSTRS INC COM 882508104 165555 1025615 SH DFND 1 1025615 0 0 TEXAS INSTRS INC COM 882508104 51877 321381 SH DFND 2 321381 0 0 TEXAS INSTRS INC COM 882508104 14 87 SH SOLE 87 0 0 TFI INTL INC COM 87241L109 305 5930 SH DFND 1 5930 0 0 TFI INTL INC COM 87241L109 864 16800 SH DFND 2 16800 0 0 THE TRADE DESK INC COM CL A 88339J105 3654 4397 SH DFND 1 4397 0 0 THE TRADE DESK INC COM CL A 88339J105 1 1 SH SOLE 1 0 0 THERAPEUTICSMD INC COM 88338N107 81 69500 SH DFND 2 69500 0 0 THERAVANCE BIOPHARMA INC COM G8807B106 1174 66250 SH DFND 2 66250 0 0 THERMO FISHER SCIENTIFIC INC COM 883556102 97838 209934 SH DFND 1 209934 0 0 THERMO FISHER SCIENTIFIC INC COM 883556102 67957 145817 SH DFND 2 145817 0 0 THERMO FISHER SCIENTIFIC INC COM 883556102 15 32 SH SOLE 32 0 0 THOMSON REUTERS CORP. COM NEW 884903709 979 11972 SH DFND 1 11972 0 0 THOR INDS INC COM 885160101 516 5300 SH DFND 2 5300 0 0 TIFFANY & CO NEW COM 886547108 2282 17413 SH DFND 1 17413 0 0 TIFFANY & CO NEW COM 886547108 1 7 SH SOLE 7 0 0 TJX COS INC NEW COM 872540109 19791 292507 SH DFND 1 292507 0 0 TJX COS INC NEW COM 872540109 18246 269673 SH DFND 2 269673 0 0 TJX COS INC NEW COM 872540109 6 91 SH SOLE 91 0 0 TOLL BROTHERS INC COM 889478103 337 7493 SH DFND 1 7493 0 0 TOOTSIE ROLL INDS INC COM 890516107 1126 38144 SH DFND 1 38144 0 0 TOPBUILD CORP COM 89055F103 125 668 SH DFND 1 668 0 0 TORM PLC SHS CL A G89479102 13 1813 SH DFND 1 1813 0 0 TORO CO COM 891092108 105 1127 SH DFND 1 1127 0 0 TORO CO COM 891092108 213 2278 SH DFND 2 2278 0 0 TORONTO DOMINION BK ONT COM NEW 891160509 103044 1840192 SH DFND 1 1840192 0 0 TORONTO DOMINION BK ONT COM NEW 891160509 6074 108480 SH DFND 2 108480 0 0 TOWER SEMICONDUCTOR LTD SHS NEW M87915274 34 1329 SH DFND 1 1329 0 0 TPG PACE BEN FIN CORP CL A COM G8990D125 2733 100000 SH DFND 1 100000 0 0 TPI COMPOSITES INC COM 87266J104 10284 200000 SH DFND 1 200000 0 0 TRACTOR SUPPLY CO COM 892356106 2854 20030 SH DFND 1 20030 0 0 TRACTOR SUPPLY CO COM 892356106 115 810 SH DFND 2 810 0 0 TRACTOR SUPPLY CO COM 892356106 1 7 SH SOLE 7 0 0 TRADEWEB MKTS INC CL A 892672106 313 5081 SH DFND 1 5081 0 0 TRANE TECHNOLOGIES PLC SHS G8994E103 53234 369866 SH DFND 1 369866 0 0 TRANE TECHNOLOGIES PLC SHS G8994E103 8416 58474 SH DFND 2 58474 0 0 TRANE TECHNOLOGIES PLC SHS G8994E103 2 15 SH SOLE 15 0 0 TRANSDIGM GROUP INC COM 893641100 3275 5458 SH DFND 1 5458 0 0 TRANSDIGM GROUP INC COM 893641100 1 2 SH SOLE 2 0 0 TRANSLATE BIO INC COM 89374L104 1234 63300 SH DFND 2 63300 0 0 TRANSUNION COM 89400J107 3080 31495 SH DFND 1 31495 0 0 TRANSUNION COM 89400J107 1271 13000 SH DFND 2 13000 0 0 TRANSUNION COM 89400J107 1 12 SH SOLE 12 0 0 TRAVELERS COMPANIES INC COM 89417E109 7296 52746 SH DFND 1 52746 0 0 TRAVELERS COMPANIES INC COM 89417E109 3423 24748 SH DFND 2 24748 0 0 TRAVELERS COMPANIES INC COM 89417E109 3 21 SH SOLE 21 0 0 TRAVERE THERAPEUTICS INC COM 89422G107 386 14500 SH DFND 2 14500 0 0 TREX CO INC COM 89531P105 4605 55870 SH DFND 1 55870 0 0 TREX CO INC COM 89531P105 3973 48200 SH DFND 2 48200 0 0 TRICIDA INC COM 89610F101 120 16500 SH DFND 2 16500 0 0 TRIMBLE INC COM 896239100 7786 119427 SH DFND 1 119427 0 0 TRIMBLE INC COM 896239100 1 10 SH SOLE 10 0 0 TRINET GROUP INC COM 896288107 67 836 SH DFND 1 836 0 0 TRIP COM GROUP LTD ADS 89677Q107 4782 149525 SH DFND 1 149525 0 0 TRIP COM GROUP LTD ADS 89677Q107 70 2200 SH DFND 2 2200 0 0 TRUIST FINL CORP COM 89832Q109 11907 254724 SH DFND 1 254724 0 0 TRUIST FINL CORP COM 89832Q109 4 84 SH SOLE 84 0 0 TURNING POINT THERAPEUTICS I COM 90041T108 1847 15350 SH DFND 2 15350 0 0 TWILIO INC CL A 90138F102 5156 14601 SH DFND 1 14601 0 0 TWILIO INC CL A 90138F102 37430 106000 SH DFND 2 106000 0 0 TWIST BIOSCIENCE CORP COM 90184D100 1786 12000 SH DFND 2 12000 0 0 TWITTER INC COM 90184L102 15403 283662 SH DFND 1 283662 0 0 TWITTER INC COM 90184L102 2 43 SH SOLE 43 0 0 TYLER TECHNOLOGIES INC COM 902252105 3255 7559 SH DFND 1 7559 0 0 TYLER TECHNOLOGIES INC COM 902252105 2260 5250 SH DFND 2 5250 0 0 TYLER TECHNOLOGIES INC COM 902252105 0 1 SH SOLE 1 0 0 TYSON FOODS INC CL A 902494103 4133 65535 SH DFND 1 65535 0 0 TYSON FOODS INC CL A 902494103 624 9900 SH DFND 2 9900 0 0 TYSON FOODS INC CL A 902494103 1 14 SH SOLE 14 0 0 UBER TECHNOLOGIES INC COM 90353T100 10995 210751 SH DFND 1 210751 0 0 UBER TECHNOLOGIES INC COM 90353T100 30363 582000 SH DFND 2 582000 0 0 UBER TECHNOLOGIES INC COM 90353T100 3 50 SH SOLE 50 0 0 UBS GROUP AG SHS H42097107 148479 10478405 SH DFND 1 10478405 0 0 UBS GROUP AG SHS H42097107 14321 1010665 SH DFND 2 1010665 0 0 UDR INC COM 902653104 6867 184850 SH DFND 1 184850 0 0 UDR INC COM 902653104 1 20 SH SOLE 20 0 0 UFP INDUSTRIES INC COM 90278Q108 173 3054 SH DFND 1 3054 0 0 UGI CORP NEW COM 902681105 1250 36448 SH DFND 1 36448 0 0 UGI CORP NEW COM 902681105 0 3 SH SOLE 3 0 0 ULTA BEAUTY INC COM 90384S303 1531 5507 SH DFND 1 5507 0 0 ULTA BEAUTY INC COM 90384S303 1 4 SH SOLE 4 0 0 ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 2475 16910 SH DFND 2 16910 0 0 UNDER ARMOUR INC CL A 904311107 11 628 SH DFND 1 628 0 0 UNDER ARMOUR INC CL C 904311206 9 648 SH DFND 1 648 0 0 UNIFIRST CORP MASS COM 904708104 541 2618 SH DFND 2 2618 0 0 UNION PAC CORP COM 907818108 25532 125106 SH DFND 1 125106 0 0 UNION PAC CORP COM 907818108 6799 33315 SH DFND 2 33315 0 0 UNION PAC CORP COM 907818108 6 31 SH SOLE 31 0 0 UNIQURE NV SHS N90064101 589 16300 SH DFND 2 16300 0 0 UNITED AIRLS HLDGS INC COM 910047109 323 7335 SH DFND 1 7335 0 0 UNITED NAT FOODS INC COM 911163103 66 4186 SH DFND 1 4186 0 0 UNITED PARCEL SERVICE INC CL B 911312106 35188 206534 SH DFND 1 206534 0 0 UNITED PARCEL SERVICE INC CL B 911312106 17629 103472 SH DFND 2 103472 0 0 UNITED PARCEL SERVICE INC CL B 911312106 7 41 SH SOLE 41 0 0 UNITED RENTALS INC COM 911363109 16312 72113 SH DFND 1 72113 0 0 UNITED RENTALS INC COM 911363109 1696 7500 SH DFND 2 7500 0 0 UNITED RENTALS INC COM 911363109 2 7 SH SOLE 7 0 0 UNITED THERAPEUTICS CORP DEL COM 91307C102 2634 17550 SH DFND 2 17550 0 0 UNITEDHEALTH GROUP INC COM 91324P102 86933 250641 SH DFND 1 250641 0 0 UNITEDHEALTH GROUP INC COM 91324P102 54953 158440 SH DFND 2 158440 0 0 UNITY BIOTECHNOLOGY INC COM 91381U101 67 13000 SH DFND 2 13000 0 0 UNIVERSAL DISPLAY CORP COM 91347P105 3040 13300 SH DFND 1 13300 0 0 UNIVERSAL HLTH SVCS INC CL B 913903100 874 6399 SH DFND 1 6399 0 0 UNIVERSAL HLTH SVCS INC CL B 913903100 2076 15200 SH DFND 2 15200 0 0 UNUM GROUP COM 91529Y106 556 24988 SH DFND 1 24988 0 0 UNUM GROUP COM 91529Y106 790 35500 SH DFND 2 35500 0 0 UROGEN PHARMA LTD COM M96088105 132 7700 SH DFND 2 7700 0 0 US BANCORP DEL COM NEW 902973304 17810 386288 SH DFND 1 386288 0 0 US BANCORP DEL COM NEW 902973304 9598 208182 SH DFND 2 208182 0 0 US BANCORP DEL COM NEW 902973304 6 120 SH SOLE 120 0 0 V F CORP COM 918204108 48902 579488 SH DFND 1 579488 0 0 V F CORP COM 918204108 2 29 SH SOLE 29 0 0 VAIL RESORTS INC COM 91879Q109 4592 16967 SH DFND 1 16967 0 0 VAIL RESORTS INC COM 91879Q109 1 3 SH SOLE 3 0 0 VALE S A SPONSORED ADS 91912E105 1903 112071 SH DFND 1 112071 0 0 VALE S A SPONSORED ADS 91912E105 6211 365873 SH DFND 2 365873 0 0 VALERO ENERGY CORP COM 91913Y100 3202 57240 SH DFND 1 57240 0 0 VALERO ENERGY CORP COM 91913Y100 2221 39700 SH DFND 2 39700 0 0 VALERO ENERGY CORP COM 91913Y100 0 5 SH SOLE 5 0 0 VALMONT INDS INC COM 920253101 286 1675 SH DFND 1 1675 0 0 VANDA PHARMACEUTICALS INC COM 921659108 102 7900 SH DFND 2 7900 0 0 VARIAN MED SYS INC COM 92220P105 2682 15356 SH DFND 1 15356 0 0 VARIAN MED SYS INC COM 92220P105 335 1915 SH DFND 2 1915 0 0 VARIAN MED SYS INC COM 92220P105 1 6 SH SOLE 6 0 0 VARONIS SYS INC COM 922280102 929 5640 SH DFND 1 5640 0 0 VAXCYTE INC COM 92243G108 334 12000 SH DFND 2 12000 0 0 VEDANTA LIMITED SPONSORED ADR 92242Y100 424 50000 SH DFND 2 50000 0 0 VEEVA SYS INC CL A COM 922475108 4791 17493 SH DFND 1 17493 0 0 VEEVA SYS INC CL A COM 922475108 2 6 SH SOLE 6 0 0 VENTAS INC COM 92276F100 6533 133056 SH DFND 1 133056 0 0 VENTAS INC COM 92276F100 1 25 SH SOLE 25 0 0 VERACYTE INC COM 92337F107 1048 21400 SH DFND 2 21400 0 0 VEREIT INC COM 92339V100 293 6803 SH DFND 1 6803 0 0 VEREIT INC COM 92339V308 4082 109381 SH DFND 1 109381 0 0 VERISIGN INC COM 92343E102 4672 21624 SH DFND 1 21624 0 0 VERISIGN INC COM 92343E102 13905 64354 SH DFND 2 64354 0 0 VERISIGN INC COM 92343E102 2 10 SH SOLE 10 0 0 VERISK ANALYTICS INC COM 92345Y106 8104 39376 SH DFND 1 39376 0 0 VERISK ANALYTICS INC COM 92345Y106 3689 17925 SH DFND 2 17925 0 0 VERISK ANALYTICS INC COM 92345Y106 2 12 SH SOLE 12 0 0 VERIZON COMMUNICATIONS INC COM 92343V104 185664 3145976 SH DFND 1 3145976 0 0 VERIZON COMMUNICATIONS INC COM 92343V104 70287 1190970 SH DFND 2 1190970 0 0 VERIZON COMMUNICATIONS INC COM 92343V104 17 290 SH SOLE 290 0 0 VERTEX PHARMACEUTICALS INC COM 92532F100 18015 77240 SH DFND 1 77240 0 0 VERTEX PHARMACEUTICALS INC COM 92532F100 36674 157241 SH DFND 2 157241 0 0 VERTEX PHARMACEUTICALS INC COM 92532F100 3 14 SH SOLE 14 0 0 VIACOMCBS INC CL B 92556H206 2932 80530 SH DFND 1 80530 0 0 VIACOMCBS INC CL B 92556H206 1 37 SH SOLE 37 0 0 VIATRIS INC COM 92556V106 3546 201551 SH DFND 1 201551 0 0 VIATRIS INC COM 92556V106 9885 561927 SH DFND 2 561927 0 0 VICI PPTYS INC COM 925652109 2614 104161 SH DFND 1 104161 0 0 VIELA BIO INC COM 926613100 691 19000 SH DFND 2 19000 0 0 VIPSHOP HOLDINGS LIMITED SPONSORED ADS A 92763W103 1121 43394 SH DFND 1 43394 0 0 VIR BIOTECHNOLOGY INC COM 92764N102 1089 38100 SH DFND 2 38100 0 0 VIRNETX HLDG CORP COM 92823T108 400 76000 SH DFND 1 76000 0 0 VIRTU FINL INC CL A 928254101 218 8886 SH DFND 1 8886 0 0 VIRTUSA CORP COM 92827P102 63 1250 SH DFND 1 1250 0 0 VISA INC COM CL A 92826C839 292165 1358871 SH DFND 1 1358871 0 0 VISA INC COM CL A 92826C839 39723 184754 SH DFND 2 184754 0 0 VISHAY INTERTECHNOLOGY INC COM 928298108 357 17600 SH DFND 1 17600 0 0 VISHAY INTERTECHNOLOGY INC COM 928298108 830 40900 SH DFND 2 40900 0 0 VISTRA CORP COM 92840M102 1137 60426 SH DFND 1 60426 0 0 VITAL FARMS INC COM 92847W103 288 11600 SH DFND 2 11600 0 0 VMWARE INC CL A COM 928563402 4423 31856 SH DFND 1 31856 0 0 VMWARE INC CL A COM 928563402 5 35 SH SOLE 35 0 0 VONTIER CORPORATION COM 928881101 96 2927 SH DFND 1 2927 0 0 VONTIER CORPORATION COM 928881101 6 173 SH SOLE 173 0 0 VORNADO RLTY TR SH BEN INT 929042109 568 15800 SH DFND 1 15800 0 0 VORNADO RLTY TR SH BEN INT 929042109 0 11 SH SOLE 11 0 0 VOYA FINANCIAL INC COM 929089100 10648 185745 SH DFND 1 185745 0 0 VOYA FINANCIAL INC COM 929089100 1 18 SH SOLE 18 0 0 VOYAGER THERAPEUTICS INC COM 92915B106 67 9500 SH DFND 2 9500 0 0 VULCAN MATLS CO COM 929160109 3827 26822 SH DFND 1 26822 0 0 VULCAN MATLS CO COM 929160109 1 8 SH SOLE 8 0 0 WABTEC COM 929740108 1249 17392 SH DFND 1 17392 0 0 WABTEC COM 929740108 1250 17400 SH DFND 2 17400 0 0 WABTEC COM 929740108 1 16 SH SOLE 16 0 0 WALGREENS BOOTS ALLIANCE INC COM 931427108 6028 151697 SH DFND 1 151697 0 0 WALGREENS BOOTS ALLIANCE INC COM 931427108 8232 207140 SH DFND 2 207140 0 0 WALGREENS BOOTS ALLIANCE INC COM 931427108 3 77 SH SOLE 77 0 0 WALMART INC COM 931142103 70886 488588 SH DFND 1 488588 0 0 WALMART INC COM 931142103 22498 155068 SH DFND 2 155068 0 0 WARNER MUSIC GROUP CORP COM CL A 934550203 167 4500 SH DFND 1 4500 0 0 WASTE CONNECTIONS INC COM 94106B101 9906 97651 SH DFND 1 97651 0 0 WASTE CONNECTIONS INC COM 94106B101 1106 10900 SH DFND 2 10900 0 0 WASTE MGMT INC DEL COM 94106L109 25626 219601 SH DFND 1 219601 0 0 WASTE MGMT INC DEL COM 94106L109 48143 412563 SH DFND 2 412563 0 0 WASTE MGMT INC DEL COM 94106L109 2 21 SH SOLE 21 0 0 WATERS CORP COM 941848103 19038 77380 SH DFND 1 77380 0 0 WATERS CORP COM 941848103 5516 22420 SH DFND 2 22420 0 0 WATERS CORP COM 941848103 1 5 SH SOLE 5 0 0 WATTS WATER TECHNOLOGIES INC CL A 942749102 1657 13962 SH DFND 1 13962 0 0 WATTS WATER TECHNOLOGIES INC CL A 942749102 1174 9887 SH DFND 2 9887 0 0 WAVE LIFE SCIENCES LTD SHS Y95308105 211 27450 SH DFND 2 27450 0 0 WAYFAIR INC CL A 94419L101 1365 5839 SH DFND 1 5839 0 0 WAYFAIR INC CL A 94419L101 1 3 SH SOLE 3 0 0 WEC ENERGY GROUP INC COM 92939U106 6904 76884 SH DFND 1 76884 0 0 WEC ENERGY GROUP INC COM 92939U106 1675 18655 SH DFND 2 18655 0 0 WEC ENERGY GROUP INC COM 92939U106 1 8 SH SOLE 8 0 0 WEIBO CORP SPONSORED ADR 948596101 105 2632 SH DFND 1 2632 0 0 WEIS MKTS INC COM 948849104 152 3221 SH DFND 1 3221 0 0 WELLS FARGO CO NEW COM 949746101 14172 474097 SH DFND 1 474097 0 0 WELLS FARGO CO NEW COM 949746101 2003 67000 SH DFND 2 67000 0 0 WELLTOWER INC COM 95040Q104 6516 103763 SH DFND 1 103763 0 0 WELLTOWER INC COM 95040Q104 620 9867 SH DFND 2 9867 0 0 WELLTOWER INC COM 95040Q104 1 19 SH SOLE 19 0 0 WERNER ENTERPRISES INC COM 950755108 877 22139 SH DFND 1 22139 0 0 WERNER ENTERPRISES INC COM 950755108 1513 38189 SH DFND 2 38189 0 0 WEST PHARMACEUTICAL SVSC INC COM 955306105 3706 13329 SH DFND 1 13329 0 0 WEST PHARMACEUTICAL SVSC INC COM 955306105 1 5 SH SOLE 5 0 0 WESTERN ALLIANCE BANCORP COM 957638109 494 8300 SH DFND 1 8300 0 0 WESTERN ALLIANCE BANCORP COM 957638109 1131 19000 SH DFND 2 19000 0 0 WESTERN DIGITAL CORP. COM 958102105 5453 113404 SH DFND 1 113404 0 0 WESTERN DIGITAL CORP. COM 958102105 2121 44100 SH DFND 2 44100 0 0 WESTERN DIGITAL CORP. COM 958102105 0 9 SH SOLE 9 0 0 WESTERN UN CO COM 959802109 4528 209730 SH DFND 1 209730 0 0 WESTERN UN CO COM 959802109 1905 88224 SH DFND 2 88224 0 0 WESTERN UN CO COM 959802109 1 31 SH SOLE 31 0 0 WESTROCK CO COM 96145D105 1964 45886 SH DFND 1 45886 0 0 WESTROCK CO COM 96145D105 0 11 SH SOLE 11 0 0 WEYERHAEUSER CO MTN BE COM NEW 962166104 7164 214632 SH DFND 1 214632 0 0 WEYERHAEUSER CO MTN BE COM NEW 962166104 2 48 SH SOLE 48 0 0 WHEATON PRECIOUS METALS CORP COM 962879102 65700 1550989 SH DFND 1 1550989 0 0 WHEATON PRECIOUS METALS CORP COM 962879102 1610 38000 SH DFND 2 38000 0 0 WHIRLPOOL CORP COM 963320106 1954 10546 SH DFND 1 10546 0 0 WHIRLPOOL CORP COM 963320106 1 5 SH SOLE 5 0 0 WHITE MTNS INS GROUP LTD COM G9618E107 651 662 SH DFND 1 662 0 0 WILEY JOHN & SONS INC CL A 968223206 139 3011 SH DFND 1 3011 0 0 WILLIAMS COS INC COM 969457100 3533 174071 SH DFND 1 174071 0 0 WILLIAMS COS INC COM 969457100 1319 65000 SH DFND 2 65000 0 0 WILLIAMS COS INC COM 969457100 0 15 SH SOLE 15 0 0 WILLIAMS SONOMA INC COM 969904101 628 6041 SH DFND 1 6041 0 0 WILLIS TOWERS WATSON PLC LTD SHS G96629103 8034 38873 SH DFND 1 38873 0 0 WILLIS TOWERS WATSON PLC LTD SHS G96629103 16911 81829 SH DFND 2 81829 0 0 WILLIS TOWERS WATSON PLC LTD SHS G96629103 2 9 SH SOLE 9 0 0 WILLSCOT MOBIL MINI HLDNG CO COM CL A 971378104 2380 104000 SH DFND 2 104000 0 0 WIPRO LTD SPON ADR 1 SH 97651M109 135 24296 SH DFND 1 24296 0 0 WIX COM LTD SHS M98068105 445 1758 SH DFND 1 1758 0 0 WORKDAY INC CL A 98138H101 12610 52943 SH DFND 1 52943 0 0 WORKDAY INC CL A 98138H101 2382 10000 SH DFND 2 10000 0 0 WP CAREY INC COM 92936U109 2935 41682 SH DFND 1 41682 0 0 WP CAREY INC COM 92936U109 1 10 SH SOLE 10 0 0 WPX ENERGY INC COM 98212B103 155 20000 SH DFND 2 20000 0 0 WYNN RESORTS LTD COM 983134107 922 8080 SH DFND 1 8080 0 0 XBIOTECH INC COM 98400H102 130 8500 SH DFND 2 8500 0 0 XCEL ENERGY INC COM 98389B100 7245 111121 SH DFND 1 111121 0 0 XENCOR INC COM 98401F105 1674 37800 SH DFND 2 37800 0 0 XENON PHARMACEUTICALS INC COM 98420N105 157 11000 SH DFND 2 11000 0 0 XEROX HOLDINGS CORP COM NEW 98421M106 84 3716 SH DFND 1 3716 0 0 XILINX INC COM 983919101 11991 85579 SH DFND 1 85579 0 0 XILINX INC COM 983919101 2802 20000 SH DFND 2 20000 0 0 XILINX INC COM 983919101 3 24 SH SOLE 24 0 0 XPENG INC ADS 98422D105 8315 132001 SH DFND 1 132001 0 0 XPO LOGISTICS INC COM 983793100 1789 15284 SH DFND 1 15284 0 0 XPO LOGISTICS INC COM 983793100 1 7 SH SOLE 7 0 0 XYLEM INC COM 98419M100 20697 207718 SH DFND 1 207718 0 0 XYLEM INC COM 98419M100 3433 34450 SH DFND 2 34450 0 0 XYLEM INC COM 98419M100 1 12 SH SOLE 12 0 0 Y- MABS THERAPEUTICS INC COM 984241109 640 12700 SH DFND 2 12700 0 0 YAMANA GOLD INC COM 98462Y100 3265 581327 SH DFND 1 581327 0 0 YAMANA GOLD INC COM 98462Y100 880 156700 SH DFND 2 156700 0 0 YANDEX N V SHS CLASS A N97284108 1710 25500 SH DFND 1 25500 0 0 YANDEX N V SHS CLASS A N97284108 17426 259870 SH DFND 2 259870 0 0 YETI HLDGS INC COM 98585X104 1405 20634 SH DFND 1 20634 0 0 YUM BRANDS INC COM 988498101 6111 55449 SH DFND 1 55449 0 0 YUM BRANDS INC COM 988498101 321 2910 SH DFND 2 2910 0 0 YUM BRANDS INC COM 988498101 1 13 SH SOLE 13 0 0 YUM CHINA HLDGS INC COM 98850P109 1601 28291 SH DFND 1 28291 0 0 YUM CHINA HLDGS INC COM 98850P109 9462 167218 SH DFND 2 167218 0 0 ZAI LAB LTD ADR 98887Q104 582 4506 SH DFND 1 4506 0 0 ZAI LAB LTD ADR 98887Q104 2067 16000 SH DFND 2 16000 0 0 ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 17586 46567 SH DFND 1 46567 0 0 ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 3211 8502 SH DFND 2 8502 0 0 ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 2 4 SH SOLE 4 0 0 ZENDESK INC COM 98936J101 1705 12331 SH DFND 1 12331 0 0 ZENTALIS PHARMACEUTICALS INC COM 98943L107 725 13300 SH DFND 2 13300 0 0 ZILLOW GROUP INC CL A 98954M101 579 4240 SH DFND 1 4240 0 0 ZILLOW GROUP INC CL C CAP STK 98954M200 1869 14337 SH DFND 1 14337 0 0 ZIMMER BIOMET HOLDINGS INC COM 98956P102 5219 34214 SH DFND 1 34214 0 0 ZIMMER BIOMET HOLDINGS INC COM 98956P102 610 4000 SH DFND 2 4000 0 0 ZIONS BANCORPORATION N A COM 989701107 227 5342 SH DFND 1 5342 0 0 ZIONS BANCORPORATION N A COM 989701107 11 249 SH SOLE 249 0 0 ZIOPHARM ONCOLOGY INC COM 98973P101 177 70000 SH DFND 2 70000 0 0 ZIX CORP COM 98974P100 409 48800 SH DFND 1 48800 0 0 ZOETIS INC CL A 98978V103 19293 118960 SH DFND 1 118960 0 0 ZOETIS INC CL A 98978V103 17187 105974 SH DFND 2 105974 0 0 ZOETIS INC CL A 98978V103 6 34 SH SOLE 34 0 0 ZOGENIX INC COM NEW 98978L204 362 18600 SH DFND 2 18600 0 0 ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 16312 45568 SH DFND 1 45568 0 0 ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 50607 141370 SH DFND 2 141370 0 0 ZSCALER INC COM 98980G102 2214 11108 SH DFND 1 11108 0 0 ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105 528 18987 SH DFND 1 18987 0 0 ZYMEWORKS INC COM 98985W102 309 6700 SH DFND 2 6700 0 0 ZYNGA INC CL A 98986T108 1235 129050 SH DFND 1 129050 0 0