Equity-based Compensation (Tables)

6 Months Ended

Jun. 30, 2022

Equity-based Compensation

Schedule of fair value of options granted using the Black-Scholes option pricing model

	Six Months Ended June 30,
	2022	2021
Fair value of common stock	$1.92 – $3.05	$1.75 – $6.15
Expected volatility	91.09% – 92.72%	100.82% – 101.83%
Risk-free interest rate	1.87% –  3.25%	0.67% – 1.06%
Dividend yield	0.00%	0.00%
Expected term (years)	5.50 – 6.08	5.00 – 6.22

Summary of activity for options

	Options Outstanding
						Weighted
		Weighted-		Aggregate		Average
		Average		Intrinsic		Remaining
	Number of	Exercise		Value		Contractual Life
	Options	Price		(in 000’s)		(In Years)
Balance, December 31, 2021	5,640,438	$	4.19	$	12,002	8.0
Options granted	426,575	$	2.52
Options exercised	(367,875)	$	0.89
Options forfeited	(422,870)	$	5.49
Options expired	(41,737)	$	0.87
Balance, June 30, 2022	5,234,531	$	4.26	$	3,720	7.1
Exercisable as of June 30, 2022	3,350,614	$	3.02	$	3,125	6.1
Vested and expected to vest as of June 30, 2022	5,234,531	$	4.26	$	3,720	7.1

Schedule of total equity-based compensation expense

	Three Months Ended June 30,				Six Months Ended June 30,
	2022		2021		2022		2021
Research and development	$	82	$	13	$	316	$	34
General and administrative		810		81		1,577		158
Total equity-based compensation	$	892	$	94	$	1,893	$	192