<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0708</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001454263</cik>
        <entityName>STAGEZERO LIFE SCIENCES LTD.</entityName>
        <issuerAddress>
            <street1>70 EAST BEAVER CREEK ROAD</street1>
            <street2>UNIT 30</street2>
            <city>RICHMOND HILL</city>
            <stateOrCountry>A6</stateOrCountry>
            <stateOrCountryDescription>ONTARIO, CANADA</stateOrCountryDescription>
            <zipCode>L4B 3B2</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>905-209-2030</issuerPhoneNumber>
        <jurisdictionOfInc>ONTARIO, CANADA</jurisdictionOfInc>
        <issuerPreviousNameList>
            <previousName>ChondroGene Limited</previousName>
            <previousName>Lewis Brook Resources Ltd.</previousName>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <previousName>GENENEWS LTD</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>James</firstName>
                <middleName>R.</middleName>
                <lastName>Howard-Tripp</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>70 East Beaver Creek Road</street1>
                <street2>Unit 30</street2>
                <city>Richmond Hill</city>
                <stateOrCountry>A6</stateOrCountry>
                <stateOrCountryDescription>ONTARIO, CANADA</stateOrCountryDescription>
                <zipCode>L4B 3B2</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Harry</firstName>
                <lastName>Glorikian</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>70 East Beaver Creek Road</street1>
                <street2>Unit 30</street2>
                <city>Richmond Hill</city>
                <stateOrCountry>A6</stateOrCountry>
                <stateOrCountryDescription>ONTARIO, CANADA</stateOrCountryDescription>
                <zipCode>L4B 3B2</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Garth</firstName>
                <lastName>MacRae</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>70 East Beaver Creek Road</street1>
                <street2>Unit 30</street2>
                <city>Richmond Hill</city>
                <stateOrCountry>A6</stateOrCountry>
                <stateOrCountryDescription>ONTARIO, CANADA</stateOrCountryDescription>
                <zipCode>L4B 3B2</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Richard</firstName>
                <middleName>Janice</middleName>
                <lastName>Huston</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>70 East Beaver Creek Road</street1>
                <street2>Unit 30</street2>
                <city>Richmond Hill</city>
                <stateOrCountry>A6</stateOrCountry>
                <stateOrCountryDescription>ONTARIO, CANADA</stateOrCountryDescription>
                <zipCode>L4B 3B2</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Rory</firstName>
                <lastName>Riggs</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>70 East Beaver Creek Road</street1>
                <street2>Unit 30</street2>
                <city>Richmond Hill</city>
                <stateOrCountry>A6</stateOrCountry>
                <stateOrCountryDescription>ONTARIO, CANADA</stateOrCountryDescription>
                <zipCode>L4B 3B2</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$5,000,001 - $25,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06b</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2022-03-02</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>true</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isEquityType>true</isEquityType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
            <isOtherType>true</isOtherType>
            <descriptionOfOtherType>Each unit consists of one common share and one transferable share purchase warrant.  Each whole warrant is exercisable for one additional share until March 2, 2026 at Cdn$0.2206 per share.</descriptionOfOtherType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>H.C. Wainwright &amp; Co., LLC</recipientName>
                <recipientCRDNumber>375</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>430 Park Avenue</street1>
                    <street2>4th Floor</street2>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10022</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>NY</state>
                    <description>NEW YORK</description>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>3217557</totalOfferingAmount>
            <totalAmountSold>1476161</totalAmountSold>
            <totalRemaining>1741396</totalRemaining>
            <clarificationOfResponse>The additional $1,741,396.00 may be received upon the exercise of share purchase warrants sold inside or outside the U.S. Dollar amounts are based on the Bank of Canada average rate of exchange reported on March 2, 2022, which wad Cdn$1.2668=USD$1.00.</clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>1</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>227882</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse>Includes broker warrants to purchase 800,000 common shares of the issuer at Cdn$0.2206 per share for a period of 4 years.</clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse>In the ordinary course of business, the issuer may use some of the proceeds of the offering to pay salaries to certain of its executive officers and directors.</clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>STAGEZERO LIFE SCIENCES LTD.</issuerName>
                <signatureName>Matthew Pietras</signatureName>
                <nameOfSigner>Matthew Peitras</nameOfSigner>
                <signatureTitle>CFO &amp; COO</signatureTitle>
                <signatureDate>2022-03-17</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
