X0306 4 2013-02-14 0 0001453814 Medidata Solutions, Inc. MDSO 0001529711 Spielman Bryan Charles C/O MEDIDATA SOLUTIONS, INC. 79 FIFTH AVENUE, 8TH FLOOR NEW YORK NY 10003 0 0 0 1 EVP, Strategy & Corp. Dvpmt. Common Stock 2013-02-14 4 A 0 8776 0 A 15480 D Common Stock 2013-02-14 4 A 0 4382 0 A 19862 D Restricted Stock Units (Performance Related) 0 2013-02-14 4 A 0 4382 0 A Common Stock 4382 4382 D Award of shares of restricted stock under the issuer's 2009 Long-Term Incentive Plan (the "2009 LTIP") on February 14, 2013. The restrictions will lapse with respect to all of the shares on December 31, 2013. Award of shares of restricted stock under the 2009 LTIP on February 14, 2013. The restrictions will lapse with respect to one-fourth of the shares on each of February 14, 2014, February 14, 2015, February 14, 2016 and February 14, 2017. Award of performance-based restricted stock units ("PBRSUs") under the 2009 LTIP on February 14, 2013. The number of PBRSUs reported represents a target grant amount. Each PBRSU represents a contingent right to receive 0-200% of that target number of shares of the issuer's common stock, based on the issuer's relative total shareholder return ("TSR") as compared to the TSR of companies listed on in the NASDAQ-100 Index/ NASDAQ Composite Index for the year ending December 31, 2013. The actual number of shares that will be issued, if at all, in settlement of the PBRSUs may range from 0% to 200% of the target grant and will vest in annual installments on February 14, 2014, February 14, 2015 and February 14, 2016. The reporting person also received additional awarded PBRSUs, all subject to corporate financial performance metrics. /s/ Michael I. Otner, Attorney-in-Fact 2013-02-19