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Commitments and Contingencies (Details)
$ in Thousands
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2016
USD ($)
Jun. 30, 2015
USD ($)
Jun. 30, 2016
USD ($)
Jun. 30, 2015
USD ($)
Dec. 31, 2015
USD ($)
Dec. 31, 2012
USD ($)
Apr. 30, 2015
ft²
Deferred rent and lease incentive liability $ 300   $ 300   $ 500    
Current portion of deferred rent and lease incentive 312   312   405    
Sublease income         200    
Rent expense, net of sublease payments 300 $ 300 700 $ 500      
2016         1,200    
2017         $ 300    
Restricted cash and other deposits | Letter of Credit              
Letter of credit $ 300   $ 300        
Laboratory and office space              
Square feet of space | ft²             13,711
Laboratory And Office Space Agreement Amendment April 2015              
Square feet of space | ft²             15,174
Maximum | Laboratory and office space              
Tenant improvement allowance           $ 700