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Nature of the Business and Basis of Presentation - Liquidity (Details) - USD ($)
$ in Thousands
Sep. 30, 2020
Dec. 31, 2019
Sep. 30, 2019
Dec. 31, 2018
Cash and Cash Equivalents [Line Items]        
Cash, cash equivalents, and restricted cash $ 147,640 $ 91,551 $ 35,892 $ 37,682
Restricted cash and cash equivalents 1,400      
Accumulated deficit 389,183 $ 335,753    
Russian subsidiary        
Cash and Cash Equivalents [Line Items]        
Cash maintained in Russian bank accounts $ 300