Income Taxes Reconciliation of Income Taxes (Details)	12 Months Ended
Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Income Tax Disclosure [Abstract]
Statutory U.S. federal rate	21.00%	21.00%	34.00%
State income taxes - net of federal benefit	6.30%	7.00%	5.80%
Permanent items	(2.10%)	(0.50%)	(0.10%)
Research tax credits/other	1.10%	1.60%	0.50%
Change in enacted rates	0.00%	0.00%	(35.80%)
Valuation allowance, net	(26.30%)	(29.10%)	(6.70%)
Other	0.00%	0.00%	2.30%
Effective income tax rate	0.00%	0.00%	0.00%

Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations applicable to state and local income tax expense (benefit), net of federal tax expense (benefit).

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to tax credits. Including, but not limited to, research credit, foreign tax credit, investment tax credit, and other tax credits.

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