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Income Taxes (Details) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2014
Dec. 31, 2019
Income Tax Holiday [Line Items]        
Unrecognized tax benefits       $ 0
Net operating loss carryforwards $ 59,126,000     71,270,000
Valuation allowance, deferred tax asset, increase (decrease), amount 14,600,000 $ 18,500,000    
Income tax holiday term     10 years  
Research and development credits 5,780,000     6,586,000
Accrued interest related to uncertain tax positions       $ 0
State and Local Jurisdiction        
Income Tax Holiday [Line Items]        
Operating loss carryforwards 256,500,000      
Research and development credits 3,000,000.0      
Domestic Tax Authority        
Income Tax Holiday [Line Items]        
Operating loss carryforwards 262,200,000      
Operating loss carryforwards, carried forward indefinitely 99,700,000      
Research and development credits $ 4,200,000