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Net Loss Per Share
12 Months Ended
Dec. 31, 2019
Earnings Per Share [Abstract]  
Net Loss Per Share Net Loss Per Share
The Company has reported a net loss for the years ended December 31, 2019, 2018, and 2017. For this reason basic and diluted net loss per share are the same for all periods presented. Since the shares underlying the 8,342,128 pre-funded warrants are issuable for little or no consideration, they are considered outstanding for both basic and diluted earnings per share. The following table sets forth the computation of basic and diluted net loss per share (in thousands, except share and per‑share data):
 
Year Ended December 31,
 
2019
 
2018
 
2017
Numerator:
 
 
 
 
 
Net loss attributable to common stockholders
$
(55,350
)
 
$
(65,336
)

$
(65,321
)
Denominator:
 
 
 
 
 
Weighted‑average common shares and pre-funded warrants outstanding—basic and diluted
45,548,511

 
22,389,286

 
20,425,050

Net loss per share attributable to common stockholders —basic and diluted
$
(1.22
)
 
$
(2.92
)
 
$
(3.20
)


All potential dilutive common shares have been excluded from the computation of the diluted net loss per share for all periods presented, as the effect would have been anti-dilutive. Potential dilutive common share equivalents consist of the following:
 
Year Ended December 31,
 
2019
 
2018
 
2017
Stock options to purchase common stock
6,796,669

 
4,093,979

 
2,657,187

Unvested restricted stock units
181,250

 
175,000

 

Stock warrants to purchase common stock
23,084,120

 
95,619

 
176,432

Total
30,062,039

 
4,364,598

 
2,833,619