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Subsequent Events (Details Narrative) - USD ($)
3 Months Ended
Apr. 05, 2019
Apr. 04, 2019
Apr. 01, 2019
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Sep. 17, 2018
Issuance of warrants to purchase a common stock             1,200,000
Exercise price of warrants       $ 7.33   $ 7.33 $ 0.01
Warrants expiration date             Aug. 01, 2028
Operating lease description       Expiration dates between 2019 and 2025      
Monthly rental fee       $ 100,000 $ 200,000    
2019 Warrants [Member]              
Fair value of warrants       $ 9,000      
Subsequent Event [Member] | 2019 Warrants [Member]              
Issuance of warrants to purchase a common stock     1,200,000        
Exercise price of warrants     $ 0.01        
Warrants expiration date     Apr. 01, 2029        
Fair value of warrants     $ 9        
Subsequent Event [Member] | Cardialen, Inc., [Member] | Sublease Agreement [Member]              
Operating lease description a portion of Cardialen's office space commencing April 2019, on a month-to-month basis until January 2024, unless terminated earlier upon notice of 60 days, for a monthly rental fee of approximately $2,100 for 2019.            
Monthly rental fee $ 2,100            
Subsequent Event [Member] | NYSE American LLC [Member]              
Receipt of noncompliance notification description   Specifically, the Company is not in compliance with Section 1003(a)(i) of the Company Guide with stockholders' equity of less than $2.0 million and net losses in two of its three most recent fiscal years, Section 1003(a)(ii) with stockholders' equity of less than $4.0 million and net losses in three of its four most recent fiscal years, and Section 1003(a)(iii) with stockholders' equity of less than $6.0 million and net losses in its five most recent fiscal years.