X0206 3 2022-08-25 0 0001453593 Xtant Medical Holdings, Inc. XTNT 0001559834 Vizirgianakis Stavros G. 664 CRUISER LANE BELGRADE MT 59714 1 0 0 0 Common Stock, $0.000001 par value 3515079 D Warrant 0.48 2022-08-25 2027-08-25 Common Stock 878770 D Consists of 3,515,079 shares issued in connection with the first closing of the private placement (the "Private Placement") pursuant to the securities purchase agreement by and among Xtant Medical Holdings, Inc. and several accredited investors. Does not include 2,264,861 shares to be issued in connection with the second closing of the Private Placement, which will be issued subject to the satisfaction of certain closing conditions. Consists of a warrant to purchase 878,770 shares in connection with the first closing of the Private Placement. Does not include a warrant to purchase 566,214 shares to be issued in connection with the second closing of the Private Placement, which will be issued subject to the satisfaction of certain closing conditions. /s/ Amy Culbert, attorney-in-fact 2022-08-26