X0306 4 2020-11-15 0 0001453593 Xtant Medical Holdings, Inc. XTNT 0001790461 Browne Sean E 664 CRUISER LANE BELGRADE MT 59714 1 1 0 0 President and Chief Executive Common Stock, $0.000001 par value 2020-11-15 4 A 0 1468859 0 A 1797903 D Stock Option 1.26 2020-11-15 4 A 0 1468859 0 A 2030-11-15 Common Stock 1468859 1468859 D These shares will vest and be issued with respect to 367,215 shares on each of October 15, 2021, October 15, 2022, and October 15, 2023 and with respect to 367,214 shares on October 15, 2024 pursuant to a restricted stock unit award granted under the Xtant Medical Holdings, Inc. Amended and Restated 2018 Equity Incentive Plan, conditioned upon the reporting person remaining an employee of Xtant through the vesting date. Includes 263,235 shares that will be issued over time subject to vesting pursuant to a restricted stock unit granted under the Xtant Medical Holdings, Inc. 2018 Equity Incentive Plan and 1,468,859 shares that will be issued over time subject to vesting pursuant to a restricted stock unit granted under the Xtant Medical Holdings, Inc. Amended and Restated 2018 Equity Incentive Plan. This option vests with respect to 367,215 shares on each of October 15, 2021, October 15, 2022, and October 15, 2023 and with respect to 367,214 shares on October 15, 2024 pursuant to an option award granted under the Xtant Medical Holdings, Inc. Amended and Restated 2018 Equity Incentive Plan, conditioned upon the reporting person remaining an employee of Xtant through the vesting date. /s/ Amy E. Culbert, attorney-in-fact 2020-11-16