<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0305</schemaVersion>

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    <periodOfReport>2012-06-14</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001394159</issuerCik>
        <issuerName>Orbitz Worldwide, Inc.</issuerName>
        <issuerTradingSymbol>OWW</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001453413</rptOwnerCik>
            <rptOwnerName>Harford Barney</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ORBITZ WORLDWIDE, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>500 W. MADISON STREET, SUITE 1000</rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60661</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>CEO</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

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                <value>Common Stock</value>
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                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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            <transactionAmounts>
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                    <value>47571</value>
                </transactionShares>
                <transactionPricePerShare>
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                </sharesOwnedFollowingTransaction>
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                </directOrIndirectOwnership>
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            <expirationDate>
                <value>2015-06-14</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>33679</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
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                <sharesOwnedFollowingTransaction>
                    <value>291321</value>
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            </expirationDate>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>47571</value>
                </underlyingSecurityShares>
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                </sharesOwnedFollowingTransaction>
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            <expirationDate>
                <value>2015-06-14</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>28497</value>
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                    <value>234747</value>
                </sharesOwnedFollowingTransaction>
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                    <value>D</value>
                </directOrIndirectOwnership>
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        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Restricted Stock Units</value>
                <footnoteId id="F3"/>
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            <transactionDate>
                <value>2012-06-14</value>
            </transactionDate>
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                <transactionFormType>4</transactionFormType>
                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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            <transactionAmounts>
                <transactionShares>
                    <value>40253</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F2"/>
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                    <value>D</value>
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            <exerciseDate>
                <footnoteId id="F8"/>
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            <expirationDate>
                <value>2015-06-14</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>40253</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>206250</value>
                </sharesOwnedFollowingTransaction>
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                    <value>D</value>
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    <footnotes>
        <footnote id="F1">Each performance-based restricted stock unit represents a contingent right to receive, in the sole discretion of the Board of Directors of the Company, either (i) one share of the Company's common stock as of the vesting date or (ii) cash equal to the fair market value of one share of the Company's common stock as of the vesting date.</footnote>
        <footnote id="F2">Each restricted stock unit represents a right to receive, in the sole discretion of the Board of Directors of Orbitz Worldwide, Inc. (the &quot;Company&quot;), either (i) one share of the Company's common stock as of the vesting date, or (ii) cash equal to the fair market value of one share of the Company's common stock as of the vesting date.</footnote>
        <footnote id="F3">Granted under the Orbitz Worldwide, Inc. 2007 Equity and Incentive Plan, as amended and restated.</footnote>
        <footnote id="F4">The performance-based restricted stock units were granted in satisfaction of the performance requirement and vest annually over four years on June 14, 2012, 2013, 2014 and 2015.</footnote>
        <footnote id="F5">The shares of common stock underlying the performance-based restricted stock units were retained (but not issued) by the Company in satisfaction of tax withholding obligations associated with the vesting of such units.</footnote>
        <footnote id="F6">The performance-based restricted stock units reported as disposed herein were settled for shares of the Company's common stock.</footnote>
        <footnote id="F7">Each restricted stock unit represents a right to receive, in the sole discretion of the Board of Directors of Orbitz Worldwide, Inc. (the &quot;Company&quot;), either (i) one share of the Company's common stock as of the vesting date, or (ii) cash equal to the fair market value of one share of the Company's common stock as of the vesting date. The shares of common stock underlying the restricted stock units reported and disposed herein were retained (but not issued) by the Company in satisfaction of tax withholding obligations associated with the vesting of such units.</footnote>
        <footnote id="F8">The restricted stock units vest annually over four years on June 14, 2012, 2013, 2014 and 2015.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Alice Geene, Attorney-in-Fact for Barney Harford</signatureName>
        <signatureDate>2012-06-18</signatureDate>
    </ownerSignature>
</ownershipDocument>
