<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2020-04-06</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000875622</issuerCik>
        <issuerName>BIOSPECIFICS TECHNOLOGIES CORP</issuerName>
        <issuerTradingSymbol>BSTC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001452429</rptOwnerCik>
            <rptOwnerName>Truitt Joseph</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O BIOSPECIFICS TECHNOLOGIES CORP.</rptOwnerStreet1>
            <rptOwnerStreet2>2 RIGHTER PKWY, DELAWARE CORP CENTER II</rptOwnerStreet2>
            <rptOwnerCity>WILMINGTON</rptOwnerCity>
            <rptOwnerState>DE</rptOwnerState>
            <rptOwnerZipCode>19803</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>See Remarks</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <footnotes></footnotes>

    <remarks>Interim Chief Executive Officer

Exhibit List Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Joseph E. Truitt, by Carl A. Valenstein, attorney-in-fact</signatureName>
        <signatureDate>2020-04-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
