X0306 4 2014-05-16 0 0001183765 THRESHOLD PHARMACEUTICALS INC THLD 0001451935 Parkinson David Ross C/O THRESHOLD PHARMACEUTICALS, INC. 170 HARBOR WAY, SUITE 300 SOUTH SAN FRANCISCO CA 94080 1 0 0 0 Stock Option (right to buy) 3.62 2014-05-16 4 A 0 20000 0.00 A 2024-05-15 Common Stock 20000 20000 D The option vests in accordance with the following schedule: (a) 8.3333% of the shares subject to this option shall vest on each monthly anniversary of the date of grant of May 16, 2014 for the first 11 months and (b) the remaining shares subject to this option shall vest on the date of the Issuer's 2015 Annual Meeting of Stockholders. /s/ David R. Parkinson 2014-05-16