X0306 4 2013-02-28 0 0001532063 Express Scripts Holding Co. ESRX 0001451222 Ebling Keith J. C/O EXPRESS SCRIPTS HOLDING COMPANY ONE EXPRESS WAY ST. LOUIS MO 63121 0 1 0 0 EVP & General Counsel Common Stock 2013-02-28 4 F 0 2524 56.93 D 69526 D Common Stock 2013-02-28 5 G 0 2534 0 D 66992 D Common Stock 2013-02-28 5 G 0 2534 0 A 57644 I By Spouse Trust #1 Common Stock 62700 I By Spouse Trust #2 Common Stock 65338 I By Reporting Person's Trust Represents shares tendered to Company to cover Reporting Person's tax liability due upon vesting of restricted stock units previously awarded under long-term incentive plans. Shares were gifted by Reporting Person to a revocable trust for the benefit of Reporting Person's spouse. Keith Ebling 2013-03-04