X0609 4 2026-06-04 0 0001447669 TWILIO INC TWLO 0001737610 Shipchandler Khozema false 101 SPEAR STREET, FIFTH FLOOR SAN FRANCISCO CA 94105 1 1 0 0 Chief Executive Officer 1 Class A Common Stock 2026-06-04 4 M 0 44158 117.94 A 279700 D Class A Common Stock 2026-06-04 4 S 0 44158 235.8836 D 235542 D Employee Stock Option (right to buy) 117.94 2026-06-04 4 M 0 44158 0 D 2030-02-21 Class A Common Stock 44158 0 D The exercise reported was executed under the Reporting Person's 10b5-1 trading plan, dated as of 2/18/2026. A portion of these shares represent Restricted Stock Units ("RSUs"). Each RSU represents a contingent right to receive one share of Issuer's Class A common stock. The sales reported were executed under the Reporting Person's 10b5-1 trading plan, dated as of 2/18/2026. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $235.88 to $236.21 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or to the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The shares underlying the option are fully vested and exercisable. /s/ Juliana Chen as attorney-in-fact for Reporting Person 2026-06-08