Leases - Narrative (Details) $ in Thousands		12 Months Ended
	May 14, 2025 USD ($) ft² renewal_option option	Dec. 31, 2025 USD ($) renewal_option facility agreement	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)
Operating Leased Assets [Line Items]
Proceeds from lease incentives received		$ 190	$ 0	$ 0
Financing Lease, Lease Not yet Commenced
Operating Leased Assets [Line Items]
Unrecorded unconditional purchase obligation		0
Operating Lease, Lease Not yet Commenced
Operating Leased Assets [Line Items]
Unrecorded unconditional purchase obligation		$ 0
Office Space
Operating Leased Assets [Line Items]
Term of contract		60 months
Office and Laboratory Facility
Operating Leased Assets [Line Items]
Lease arrangement, number of renewal options | renewal_option		2
Lessee, operating lease, renewal term		5 years
Number of facilities leased | facility		2
Number of agreements | agreement		2
Pittsburgh Office and Laboratory Facilities
Operating Leased Assets [Line Items]
Term of contract		10 years 6 months
Lessee, operating lease, renewal term		5 years
Scottsdale Lease
Operating Leased Assets [Line Items]
Lease arrangement, number of renewal options | renewal_option	2
Lessee, operating lease, renewal term	5 years
Area of real estate property | ft²	55,573
Number of monthly payments	143 months
Number of termination options | option	1
Lessee, operating lease, termination period	96 months
Provisions for lease incentives	$ 7,200
Rent for the first twelve months abatement amount	$ 1,800
Office Printers and Other Office Equipment
Operating Leased Assets [Line Items]
Finance lease, extension term		1 year
Proceeds from lease incentives received		$ 200	$ 0	$ 0