X0306 4 2016-12-01 0 0001372299 HISTOGENICS CORP HSGX 0001447150 Gridley Adam C/O HISTOGENICS CORPORATION 830 WINTER STREET, 3RD FLOOR WALTHAM MA 02451 1 1 0 0 President and CEO Common Stock 2016-12-01 4 P 0 5000 2.0079 A 5000 D The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.02 to $1.9998, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote (1) to this Form 4. /s/ Adam Gridley 2016-12-02