Condensed Consolidated Statement of Stockholders' Equity - 6 months ended Jun. 30, 2016 - USD ($) $ in Thousands	Total	Common stock	Additional paid-in capital	Deficit	Accumulated other comprehensive loss
Beginning balance (in shares) at Dec. 31, 2015		54,570,691
Beginning balance at Dec. 31, 2015	$ 547,679	$ 834,240	$ 30,206	$ (266,985)	$ (49,782)
Stock-based compensation	29,278	$ 25,950	3,328
Reclassification of equity to liability stock option awards	(3,243)		(3,243)
Certain fair value adjustments to liability stock option awards	2,676		2,676
Issuance of common shares pursuant to exercise of options (in shares)		55,550
Issuance of common shares pursuant to exercise of options	116	$ 266	(150)
Issuance of common shares pursuant to exercise of warrants (in shares)		170,500
Issuance of common shares pursuant to exercise of warrants	692	$ 692
Net loss	(145,874)			(145,874)
Ending balance (in shares) at Jun. 30, 2016		54,796,741
Ending balance at Jun. 30, 2016	$ 431,324	$ 861,148	$ 32,817	$ (412,859)	$ (49,782)