Collaborations, Contracts and licensing agreements - Licensing Agreements (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2026	Dec. 31, 2025
Research and Development Arrangement, Contract to Perform for Others [Line Items]
License receivable from Genevant	$ 178,741	$ 0
Income tax benefit	$ 0
Revenue from collaborations and licenses | Genevant
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Company's interest in settlement amount, percent	20.00%
Moderna | Revenue from collaborations and licenses | Genevant
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Noncontingent settlement amount	$ 950,000
Revenue recognized as portion of Settlement Agreement	178,700
License receivable from Genevant	$ 178,700