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Organization (Details)
$ in Thousands
2 Months Ended 12 Months Ended
Mar. 03, 2021
USD ($)
Dec. 31, 2020
USD ($)
product
Dec. 31, 2019
USD ($)
Organization, Consolidation and Presentation of Financial Statements [Abstract]      
Number of lead products | product   2  
Cash, cash equivalents and short-term investments   $ 123,300  
Class of Stock [Line Items]      
Issuance of common shares pursuant to the Open Market Sales Agreement   86,297 $ 18,601
Jefferies LLC | Common Shares | Sale Agreement      
Class of Stock [Line Items]      
Issuance of common shares pursuant to the Open Market Sales Agreement   $ 86,300 $ 19,500
Jefferies LLC | Common Shares | Sale Agreement | Subsequent event      
Class of Stock [Line Items]      
Issuance of common shares pursuant to the Open Market Sales Agreement $ 24,300