Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2020	Dec. 31, 2019
Current assets:
Cash and cash equivalents	$ 52,251	$ 31,799
Investments in marketable securities, current	71,017	59,035
Accounts receivable	1,312	1,204
Prepaid expenses and other current assets	3,124	1,790
Total current assets	127,704	93,828
Property and equipment, net of accumulated depreciation	6,927	8,676
Right of use asset	2,405	2,738
Other non-current assets	44	293
Total assets	137,080	105,535
Current liabilities:
Accounts payable and accrued liabilities	8,901	7,235
Liability-classified options	250	253
Lease liability, current	390	340
Total current liabilities	9,541	7,828
Liability related to sale of future royalties	19,554	18,992
Contingent consideration	3,426	2,953
Lease liability, non-current	2,593	3,018
Total liabilities	35,114	32,791
Stockholders' equity
Issued and outstanding: 1,164,000	149,408	137,285
Issued and outstanding: 89,678,722 (December 31, 2019: 64,780,314)	985,939	898,535
Additional paid-in capital	60,751	55,246
Deficit	(1,045,961)	(970,093)
Accumulated other comprehensive loss	(48,171)	(48,229)
Total stockholders' equity	101,966	72,744
Total liabilities and stockholders' equity	$ 137,080	$ 105,535