Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019
Revenue
Revenue	$ 1,491	$ 679
Non-cash royalty revenue	(656)	(171)
Non-cash royalty revenue
Research and development	10,416	14,712
General and administrative	3,553	4,412
Depreciation	500	509
Change in fair value of contingent consideration	112	125
Site consolidation	57	117
Total operating expenses	14,638	19,875
Total operating expenses	(13,147)	(19,196)
Loss from operations
Interest income	345	600
Interest expense	(1,041)	(12)
Foreign exchange (losses) / gains	(18)	8
Net equity investment loss	0	(4,651)
Total other loss	(714)	(4,055)
Loss before income taxes	(13,861)	(23,251)
Income tax benefit	0	0
Net loss	(13,861)	(23,251)
Items applicable to preferred shares:
Dividend accretion of convertible preferred shares	(2,978)	(2,715)
Net loss attributable to common shares	$ (16,839)	$ (25,966)
Net loss attributable to common shareholders, per share
Basic and dilutive (in USD per share)	$ (0.25)	$ (0.47)
Weighted average number of common shares
Basic and diluted (in shares)	67,683,586	55,740,121
Unrealized gain on available-for-sale securities	$ 251	$ 0
Currency translation adjustment	0	(22)
Comprehensive loss	(13,610)	(23,273)
Collaboration And Contracts [Member]
Revenue
Revenue	$ 835	$ 508