Collaborations, Contracts and Licensing Agreements (Details) - USD ($) $ in Thousands	3 Months Ended		15 Months Ended
	Mar. 31, 2020	Mar. 31, 2019	Mar. 31, 2020
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Non-cash royalty revenue	$ 656	$ 171
Revenue	1,491	679
Acuitas Therapeutics Inc. [Member]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Revenue	(800)	(300)
Other Milestone and Royalty Payments
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Revenue	(100)	(300)
OMERS
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Non-cash royalty revenue	$ (700)	(200)	$ (2,500)
Royalties
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Non-cash royalty revenue		$ (171)