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Equity method investment - Narrative (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Apr. 11, 2018
Jun. 30, 2018
Dec. 31, 2019
Dec. 31, 2018
Schedule of Equity Method Investments [Line Items]        
Ownership interest in equity method investment     40.00%  
Net equity investment gain or loss     $ (22,522) $ 19,557
Equity Method Investments     0 22,224
Genevant        
Schedule of Equity Method Investments [Line Items]        
Initial investment in Genevant $ 600      
Ownership interest in equity method investment 50.00%      
Gain on property contribution to equity method investment   $ 24,900    
Goodwill transfer to equity method investment $ 1,893      
Gain on investments     14,900 $ 5,600
Equity Method Investment, Other than Temporary Impairment     $ 7,600  
Genevant | Roivant Sciences Ltd        
Schedule of Equity Method Investments [Line Items]        
Initial investment in Genevant 37,500      
Initial capital contribution 22,500      
Commitment to contribute to equity method investment $ 15,000