Consolidated Balance Sheets - USD ($)	Dec. 31, 2019	Dec. 31, 2018
Current assets:
Cash and cash equivalents	$ 31,799,000	$ 36,942,000
Investments in marketable securities	59,035,000	87,675,000
Accounts receivable	1,204,000	1,431,000
Prepaid expenses and other assets	1,790,000	3,181,000
Total current assets	93,828,000	129,229,000
Investment in Genevant	0	22,224,000
Property and equipment, net of accumulated depreciation	8,676,000	10,145,000
Right of use asset	2,738,000	0
Intangible assets	0	43,836,000
Goodwill	0	22,471,000
Other Assets, Noncurrent	293,000	0
Total assets	105,535,000	227,905,000
Current liabilities:
Accounts payable and accrued liabilities	7,098,000	9,429,000
Site consolidation accrual	137,000	1,331,000
Liability-classified options	253,000	479,000
Lease liability, current	340,000	0
Total current liabilities	7,828,000	11,239,000
Liability related to sale of future royalties	18,992,000	0
Deferred rent and inducements, non-current	0	645,000
Business Combination, Contingent Consideration, Liability, Noncurrent	2,953,000	3,126,000
Lease liability, non-current	3,018,000	0
Deferred tax liability	0	12,661,000
Stockholders’ equity	32,791,000	27,671,000
Stockholders’ equity
Issued and outstanding: 1,164,000 (December 31, 2018: 1,164,000)	137,285,000	126,136,000
Issued and outstanding: 64,780,314 (December 31, 2018: 55,518,800)	898,535,000	879,405,000
Additional paid-in capital	55,246,000	48,084,000
Deficit	(970,093,000)	(805,221,000)
Accumulated other comprehensive loss	(48,229,000)	(48,170,000)
Total stockholders' equity	72,744,000	200,234,000
Total liabilities and stockholders' equity	$ 105,535,000	$ 227,905,000