144 0001932525 XXXXXXXX LIVE 0001446847 IRONWOOD PHARMACEUTICALS INC 001-34620 100 SUMMER STREET, SUITE 2300 BOSTON MA 02110 617-621-7722 Davis Andrew Officer Class A Common Stock E Trade Securities LLC

3 Edison Drive Alpharetta GA 30005

6090 25029.90 160028388 11/18/2024 Nasdaq Class A Common Stock 12/07/2021 Restricted Stock Unit award granted pursuant to the Issuer's 2019 Equity Incentive Plan, subject to vesting requirements Ironwood Pharmaceuticals, Inc. N 10771 12/07/2021 N/A Y Shares sold to cover taxes from the vesting of stock awards granted by the Issuer. 11/15/2024 /s/ Andrew Davis