Collaboration, License, and Other Agreements - North America - Commercial Efforts (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Collaboration, License, Promotion and Other Commercial Agreements
Revenue	$ 108,637	$ 103,747	$ 303,397	$ 296,623
Selling, general and administrative	28,619	27,742	87,604	82,446
Collaborative arrangements revenue
Collaboration, License, Promotion and Other Commercial Agreements
Revenue	108,637	103,747	303,397	295,798
Collaborative arrangements, LINZESS | AbbVie | U.S.
Collaboration, License, Promotion and Other Commercial Agreements
Selling, general and administrative	$ 8,900	$ 7,400	$ 26,200	$ 22,000