Collaboration, License, and Other Agreements - North America - Collaborative Arrangements Revenue (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenues:
Revenue	$ 108,637	$ 103,747	$ 303,397	$ 296,623
Collaborative arrangements revenue
Revenues:
Revenue	108,637	103,747	303,397	295,798
AbbVie | Royalty
Revenues:
Revenue	700	700	1,800	1,900
AbbVie | North America | Collaborative arrangements revenue
Revenues:
Revenue	106,085	101,061	296,047	288,598
AbbVie | North America | Collaborative arrangement, collaboration and license agreements
Revenues:
Revenue	106,085	101,061	296,047	288,598
AbbVie | North America | Collaborative arrangements, LINZESS
Revenues:
Revenue	105,224	100,393	293,995	286,649
AbbVie | North America | Royalty
Revenues:
Revenue	$ 861	$ 668	$ 2,052	$ 1,949