Collaboration, License, and Other Agreements - North America - Collaborative Arrangements Revenue (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenues:
Revenue	$ 97,231	$ 104,031	$ 194,760	$ 192,876
Collaborative arrangements revenue
Revenues:
Revenue	97,231	103,386	194,760	192,051
AbbVie | Royalty
Revenues:
Revenue	500	600	1,100	1,200
AbbVie | North America | Collaborative arrangements revenue
Revenues:
Revenue	95,061	101,038	189,962	187,537
AbbVie | North America | Collaborative arrangement, collaboration and license agreements
Revenues:
Revenue	95,061	101,038	189,962	187,537
AbbVie | North America | Collaborative arrangements, LINZESS
Revenues:
Revenue	94,452	100,307	188,771	186,256
AbbVie | North America | Royalty
Revenues:
Revenue	$ 609	$ 731	$ 1,191	$ 1,281