Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 593,371	$ 620,129
Accounts receivable, net	105,515	114,042
Prepaid expenses and other current assets	8,537	8,689
Restricted cash	1,250	1,250
Convertible note hedges	1,428	1,115
Total current assets	710,101	745,225
Restricted cash, net of current portion	485	485
Accounts receivable, net of current portion	14,143	23,998
Property and equipment, net	7,229	7,575
Operating lease right-of-use assets	15,028	15,350
Deferred tax assets	335,440	333,294
Other assets	955	1,000
Total assets	1,083,381	1,126,927
Current liabilities:
Accounts payable	532	935
Accrued research and development costs	5,442	15,896
Accrued expenses and other current liabilities	16,852	23,566
Current portion of operating lease liabilities	3,097	3,127
Current portion of convertible senior notes	120,581	116,858
Note hedge warrants	899	1,316
Total current liabilities	147,403	161,698
Convertible senior notes, net of current portion	395,053	337,333
Operating lease obligations, net of current portion	18,031	18,484
Other liabilities	5,111	3,501
Commitments and contingencies
Stockholders' equity:
Class A Common Stock, $0.001 par value, 500,000,000 shares authorized and 155,115,155 shares issued and outstanding at March 31, 2022 and 500,000,000 shares authorized and 162,036,461 shares issued and outstanding at December 31, 2021	155	162
Additional paid-in capital	1,350,268	1,543,357
Accumulated deficit	(832,640)	(937,608)
Total stockholders' equity	517,783	605,911
Total liabilities and stockholders' equity	$ 1,083,381	$ 1,126,927