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Collaboration, License, Co-Promotion and Other Commercial Agreements - European and Other Territories (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Oct. 31, 2015
Sep. 30, 2012
Collaboration, License and Co-Promotion Agreements            
Revenue $ 89,432 $ 102,215 $ 169,375 $ 170,945    
Collaborative arrangements revenue            
Collaboration, License and Co-Promotion Agreements            
Revenue 89,423 77,322 $ 163,868 143,474    
License | AbbVie            
Collaboration, License and Co-Promotion Agreements            
Royalty percentage, five years following the first commercial sale     upper-single digits      
Annual royalty     5 years      
Royalty percentage, thereafter     low-double digits      
Royalty percentage, expanded territory     lower-single digits      
License | AbbVie | Europe            
Collaboration, License and Co-Promotion Agreements            
Remaining milestone payment due upon the amendment to the license agreement         $ 42,500  
Revenue remaining performance obligation           $ 0
Royalty | AbbVie | Europe            
Collaboration, License and Co-Promotion Agreements            
Revenue $ 400 $ 300 $ 1,100 $ 700