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Collaboration, License, Co-Promotion and Other Commercial Agreements - China, Hong Kong and Macau (Details)
$ in Thousands
1 Months Ended 3 Months Ended
Sep. 30, 2019
USD ($)
installment
Mar. 31, 2020
USD ($)
Mar. 31, 2019
USD ($)
Collaboration, License and Co-Promotion Agreements      
Revenue   $ 79,943 $ 68,730
Collaborative arrangements revenue      
Collaboration, License and Co-Promotion Agreements      
Revenue   74,445 66,152
Sale of active pharmaceutical ingredient      
Collaboration, License and Co-Promotion Agreements      
Revenue   5,498 2,578
AstraZeneca | Sale of active pharmaceutical ingredient      
Collaboration, License and Co-Promotion Agreements      
Revenue     3
AstraZeneca | China, Hong Kong, and Macau | Collaborative arrangements revenue      
Collaboration, License and Co-Promotion Agreements      
Collaborative arrangement, significant financing component, transaction price $ 2,600    
Collaborative arrangement, expected interest income   2,600  
AstraZeneca | China, Hong Kong, and Macau | Collaborative arrangement, collaboration and license agreements      
Collaboration, License and Co-Promotion Agreements      
Revenue   332  
AstraZeneca | China, Hong Kong, and Macau | Collaborative arrangement, collaboration agreements      
Collaboration, License and Co-Promotion Agreements      
Milestone payment to be received by company upon milestone achievement 90,000    
Pre-launch commercial services and supply chain services     $ 200
Amount of non-contingent arrangement consideration $ 35,000    
Non-contingent consideration installments | installment 3    
Percentage of tiered royalties 20.00%    
Revenue   32,400  
Interest income   200  
AstraZeneca | China, Hong Kong, and Macau | Collaborative arrangement, transition services agreement      
Collaboration, License and Co-Promotion Agreements      
Regulatory and administrative services initial term 2 years    
AstraZeneca | China, Hong Kong, and Macau | Sale of active pharmaceutical ingredient      
Collaboration, License and Co-Promotion Agreements      
Revenue   $ 5,498  
AstraZeneca | China, Hong Kong, and Macau | Commercialization milestone | Collaborative arrangement, collaboration agreements      
Collaboration, License and Co-Promotion Agreements      
Percentage of net loss from commercialization (as a percent)   55.00%  
AstraZeneca Service Agreement | China, Hong Kong, and Macau | Collaborative arrangement, collaboration agreements      
Collaboration, License and Co-Promotion Agreements      
Revenue   $ 200