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Subsequent Events - Lesinurad License Agreement Termination - Reduced Projected Revenue and Net Cash Flow Assumptions (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Aug. 02, 2018
Sep. 30, 2018
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Subsequent Events            
Impairment of finite-lived intangible         $ 0  
Non-cash change in fair value of contingent consideration     $ 1,962 $ 6,933 2,474 $ 8,547
Inventory and purchase commitments write down         2,200  
Write-down of commercial supply and inventory to net realizable value and loss on non-cancellable purchase commitments     $ 1,836 $ 96 1,836 $ 96
Selling, general and administrative            
Subsequent Events            
Inventory and purchase commitments write down         $ 400  
Subsequent Event | Forecast            
Subsequent Events            
Impairment of finite-lived intangible   $ 150,000        
Non-cash change in fair value of contingent consideration   $ (30,000)        
Subsequent Event | Licensing agreement | AstraZeneca            
Subsequent Events            
Effective period from notice 180 days