Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2018	Dec. 31, 2017
Current assets:
Cash and cash equivalents	$ 145,415	$ 125,736
Available-for-sale securities	35,831	95,680
Accounts receivable, net	6,748	3,190
Related party accounts receivable, net	73,771	78,967
Inventory, net	1,099	735
Prepaid expenses and other current assets	16,678	7,288
Total current assets	279,542	311,596
Restricted cash	8,306	7,056
Property and equipment, net	16,335	17,274
Convertible note hedges	159,526	108,188
Intangible assets, net	152,953	159,905
Goodwill	785	785
Other assets	771	870
Total assets	618,218	605,674
Current liabilities:
Accounts payable and related party accounts payable, net	23,786	15,958
Accrued research and development costs	5,378	7,313
Accrued expenses and other current liabilities	37,829	38,237
Current portion of capital lease obligations	2,465	4,077
Current portion of deferred rent	242	195
Current portion of 2026 Notes	24,861
Current portion of contingent consideration	423	247
Total current liabilities	94,984	66,027
Deferred rent, net of current portion	6,058	5,449
Contingent consideration, net of current portion	33,228	31,011
Note hedge warrants	143,019	92,188
Convertible senior notes	257,206	249,193
2026 Notes, net of current portion	122,614	146,898
Other liabilities	5,060	5,060
Commitments and contingencies
Stockholders’ (deficit) equity:
Preferred stock, $0.001 par value, 75,000,000 shares authorized, no shares issued and outstanding
Additional paid-in capital	1,357,224	1,318,536
Accumulated deficit	(1,401,284)	(1,308,760)
Accumulated other comprehensive loss	(44)	(79)
Total stockholders' (deficit) equity	(43,951)	9,848
Total liabilities and stockholders’ (deficit) equity	618,218	605,674
Class A common stock
Stockholders’ (deficit) equity:
Common stock	139	137
Class B common stock
Stockholders’ (deficit) equity:
Common stock	$ 14	$ 14