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Collaboration, License, Co-Promotion and Other Commercial Agreements - North America - General Information (Details) - North America - Collaborative arrangement
$ in Millions
3 Months Ended
Mar. 31, 2018
USD ($)
item
payment
Mar. 31, 2017
USD ($)
Sales milestones    
Collaboration, License and Co-Promotion Agreements    
Sales-related milestone if certain conditions are met $ 100.0  
Allergan    
Collaboration, License and Co-Promotion Agreements    
Equity investment in the entity's capital stock 25.0  
Net cost sharing offset or incremental expense related to research and development expense 1.4 $ 1.4
Cost sharing amount, reduction to research and development $ 0.4 $ 0.4
Remaining commercial-period performance obligations | item 3  
Allergan | Development milestones    
Collaboration, License and Co-Promotion Agreements    
Cumulative license fees and development milestone payments received $ 205.0  
Number of milestone payments received | payment 6  
Allergan | Sales milestones    
Collaboration, License and Co-Promotion Agreements    
Percentage of net profit from commercialization (as a percent) 50.00%  
Percentage of net loss from commercialization (as a percent) 50.00%