Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2018	Dec. 31, 2017
Current assets:
Cash and cash equivalents	$ 144,788	$ 125,736
Available-for-sale securities	49,659	95,680
Accounts receivable, net	4,988	3,190
Related party accounts receivable, net	65,663	78,967
Inventory	1,705	735
Prepaid expenses and other current assets	8,924	7,288
Total current assets	275,727	311,596
Restricted cash	7,056	7,056
Property and equipment, net	16,844	17,274
Convertible note hedges	113,445	108,188
Intangible assets, net	156,429	159,905
Goodwill	785	785
Other assets	809	870
Total assets	571,095	605,674
Current liabilities:
Accounts payable and related party accounts payable, net	11,609	15,958
Accrued research and development costs	4,673	7,313
Accrued expenses and other current liabilities	30,145	38,237
Current portion of capital lease obligations	3,359	4,077
Current portion of deferred rent	237	195
Current portion of 2026 Notes	11,958
Current portion of contingent consideration	355	247
Total current liabilities	62,336	66,027
Deferred rent, net of current portion	5,860	5,449
Contingent consideration, net of current portion	31,389	31,011
Note hedge warrants	96,129	92,188
Convertible senior notes	253,153	249,193
2026 Notes, net of current portion	135,220	146,898
Other liabilities	5,060	5,060
Commitments and contingencies
Stockholders’ (deficit) equity:
Preferred stock, $0.001 par value, 75,000,000 shares authorized, no shares issued and outstanding
Additional paid-in capital	1,333,791	1,318,536
Accumulated deficit	(1,351,904)	(1,308,760)
Accumulated other comprehensive loss	(91)	(79)
Total stockholders' (deficit) equity	(18,052)	9,848
Total liabilities and stockholders’ (deficit) equity	571,095	605,674
Class A common stock
Stockholders’ (deficit) equity:
Common stock	138	137
Class B common stock
Stockholders’ (deficit) equity:
Common stock	$ 14	$ 14