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Collaboration, License, Co-Promotion and Other Commercial Agreements - North America (Details)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Sep. 30, 2007
Jun. 30, 2017
USD ($)
Jun. 30, 2016
USD ($)
Jun. 30, 2017
USD ($)
item
Jun. 30, 2016
USD ($)
AstraZeneca | Licensing agreement          
Collaboration, License and Co-Promotion Agreements          
Royalty percentage per agreement       single digits  
North America | Allergan | Product related collaborative arrangements          
Collaboration, License and Co-Promotion Agreements          
Equity investment in the entity's capital stock       $ 25,000  
Net cost sharing offset or incremental expense related to research and development expense   $ 500 $ 3,200 500 $ 5,200
North America | Allergan | Product related collaborative arrangements | Development milestones          
Collaboration, License and Co-Promotion Agreements          
Cumulative license fees and development milestone payments received       $ 205,000  
Number of milestone payments | item       6  
North America | Allergan | Product related collaborative arrangements | Commercialization milestone          
Collaboration, License and Co-Promotion Agreements          
Percentage of net profit from commercialization       50.00%  
Percentage of net loss from commercialization       50.00%  
North America | Future payments | Product related collaborative arrangements | Maximum | Sales milestones          
Collaboration, License and Co-Promotion Agreements          
Milestone payment to be received by company upon milestone achievement       $ 100,000  
U.S. | Allergan | Collaborative arrangement          
Collaboration, License and Co-Promotion Agreements          
Collaborative arrangements revenue related to sales of LINZESS in the U.S.   56,307 48,333 105,759 94,980
Revenue recognized from sale of API     1,465   4,482
Royalty revenue   435 238 934 547
Total collaborative arrangements revenue   56,742 50,036 106,693 100,009
U.S. | Allergan | Product related collaborative arrangements          
Collaboration, License and Co-Promotion Agreements          
Collaborative arrangements revenue related to sales of LINZESS in the U.S.   56,307 48,333 105,759 94,980
Selling, general and administrative costs incurred by the Company   (12,496) (8,879) (23,605) (18,032)
The Company's share of net profit (loss)   43,811 39,454 82,154 76,948
Canada and Mexico | Allergan | Product related collaborative arrangements          
Collaboration, License and Co-Promotion Agreements          
Royalty percentage per agreement mid-teens        
Royalty revenue   $ 400 $ 200 $ 900 $ 500