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Business Combinations - General Information (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Jun. 02, 2016
Jun. 30, 2016
Mar. 31, 2017
Lesinurad transaction      
Business Combinations      
Payment for acquisition of lesinurad license $ 100,000    
Lesinurad transaction | Adjustment      
Business Combinations      
Net assets and liabilities     $ 0
Lesinurad transaction | AstraZeneca      
Business Combinations      
Reimbursement obligation 100,000    
Payment for acquisition of lesinurad license 100,000    
Contingent consideration 67,885    
Acquisition related issuance costs   $ 1,600  
Net assets and liabilities $ 167,885    
Licensing agreement | AstraZeneca      
Business Combinations      
Period for reimbursement amount of development activities (in years) 10 years    
Milestone payment to be paid by company upon milestone achievement     $ 165,000
Royalty percentage per agreement     single digits
Commercial Supply Agreement (CSA) | Lesinurad transaction | AstraZeneca      
Business Combinations      
Time period for manufacturing technology transfer per agreement 6 months