Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2017	Dec. 31, 2016
Current assets:
Cash and cash equivalents	$ 133,319	$ 54,004
Available-for-sale securities	162,020	251,212
Accounts receivable	1,152	933
Related party accounts receivable, net	49,995	63,921
Inventory	1,513	1,081
Prepaid expenses and other current assets	8,664	9,030
Restricted cash	1,190
Total current assets	357,853	380,181
Restricted cash, net of current portion	7,057	8,247
Property and equipment, net	18,633	20,512
Convertible note hedges	150,509	132,521
Intangible assets, net	165,699	166,119
Goodwill	785	785
Other assets	783	1,456
Total assets	701,319	709,821
Current liabilities:
Accounts payable and related party accounts payable, net	20,578	17,703
Accrued research and development costs	5,106	6,937
Accrued expenses and other current liabilities	31,818	38,301
Current portion of capital lease obligations	5,501	6,227
Current portion of deferred rent	588	7,719
Deferred revenue	741
Current portion of contingent consideration	14,561	14,244
Total current liabilities	78,893	91,131
Capital lease obligations, net of current portion	21	82
Deferred rent, net of current portion	2,554	557
Contingent consideration, net of current portion	64,712	63,416
Note hedge warrants	133,424	113,237
Other liabilities	8,190	8,190
Commitments and contingencies
Stockholders' equity:
Preferred stock, $0.001 par value, 75,000,000 shares authorized, no shares issued and outstanding
Additional paid-in capital	1,273,853	1,258,398
Accumulated deficit	(1,244,324)	(1,191,823)
Accumulated other comprehensive loss	(41)	(7)
Total stockholders' equity	29,637	66,716
Total liabilities and stockholders' equity	701,319	709,821
Class A common stock
Stockholders' equity:
Common stock	134	133
Class B common stock
Stockholders' equity:
Common stock	15	15
2.25% Convertible Senior Notes due in 2022
Current liabilities:
Notes payable	237,851	234,243
11% PhaRMA Notes
Current liabilities:
Notes payable		$ 132,249
8.375% Notes due 2026
Current liabilities:
Notes payable	$ 146,037