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Note 6 - Derivatives (Details Textual) - USD ($)
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
A, B and Agent Warrants [Member]      
Derivative Liability $ 2,936   $ 3,355
Derivative, Gain (Loss) on Derivative, Net 419 $ 1,190  
Agent Warrants Issued in Connection with May 2020 Offering [Member]      
Derivative Liability 4,144   4,479
Derivative, Gain (Loss) on Derivative, Net 335 505  
Agent Warrants In Connection With June 2020 Warrant [Member]      
Derivative Liability 5,800   $ 5,999
Derivative, Gain (Loss) on Derivative, Net $ 199 $ 213