Note 11 - Segments - Segments (Details) - USD ($)		9 Months Ended	12 Months Ended
	Jun. 30, 2022	Sep. 30, 2021	Dec. 31, 2022	Dec. 31, 2021
Revenue			$ 1,505,459	$ 1,420,680
Depreciation and Amortization			(1,313,075)	(1,340,301)
Impairment	$ (7,231,093)	$ (2,813,792)	(7,231,093)	(2,813,792)
Impairment expense – intangibles			(3,349,375)	(2,893,548)
Impairment expense – Long-lived tangible assets			(185,469)	(1,249,727)
Net loss			(25,737,634)	(19,657,174)
Assets			25,734,644	43,771,271
Impairment expense – acquired software				(1,249,727)
Corporate, Non-Segment [Member]
Revenue			889	4,119
Depreciation and Amortization			(69,215)	(16,319)
Impairment expense – Long-lived tangible assets			(69,694)
Net loss			(7,761,371)	(7,089,286)
Assets			22,379,588	28,536,489
Skyline [Member] | Operating Segments [Member]
Revenue			1,063,493	1,169,811
Depreciation and Amortization			(28,481)	(30,002)
Impairment expense – Long-lived tangible assets			0
Net loss			(417,774)	(520,822)
Assets			946,394	906,977
Helomics Segment [Member] | Operating Segments [Member]
Revenue			6,397	13,367
Depreciation and Amortization			(445,686)	(886,642)
Impairment			0	(2,813,792)
Impairment expense – intangibles			0	(2,893,548)
Impairment expense – Long-lived tangible assets			0
Net loss			(4,122,444)	(11,326,948)
Assets			931,721	1,802,792
Impairment expense – acquired software				(1,249,727)
Soluble [Member] | Operating Segments [Member]
Revenue			82,301	233,293
Depreciation and Amortization			(378,708)	(366,713)
Impairment expense – Long-lived tangible assets			(115,775)
Net loss			(1,817,283)	(1,251,564)
Assets			1,353,434	1,742,445
zPREDICTA [Member] | Operating Segments [Member]
Revenue			352,379	90
Depreciation and Amortization			(390,985)	(40,625)
Impairment			(7,231,093)
Impairment expense – intangibles			(3,349,375)
Impairment expense – Long-lived tangible assets			0
Net loss			(11,618,762)	531,446
Assets			$ 123,507	$ 10,782,568