Consolidated Statements of Stockholders' Equity - USD ($)	Preferred Stock [Member] Series B Convertible Preferred Stock [Member]	Common Stock [Member] Registered Direct Offerings [Member]	Common Stock [Member] Private Placement [Member]	Common Stock [Member] June 16, 2021 Registered Direct Offering [Member]	Common Stock [Member]	Additional Paid-in Capital [Member] Registered Direct Offerings [Member]	Additional Paid-in Capital [Member] Private Placement [Member]	Additional Paid-in Capital [Member] June 16, 2021 Registered Direct Offering [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member]	Registered Direct Offerings [Member]	Private Placement [Member]	June 16, 2021 Registered Direct Offering [Member]	Total
Balance (in shares) at Dec. 31, 2020	79,246				19,804,787
Balance at Dec. 31, 2020	$ 792				$ 198,048				$ 110,826,949	$ (108,383,108)				$ 2,642,681
Issuance of shares and warrants (in shares)		13,488,098	9,043,766	15,520,911
Issuance of shares and warrants		$ 134,881	$ 90,438	$ 155,209		$ 14,877,611	$ 15,974,301	$ 19,291,087			$ 15,012,492	$ 16,064,739	$ 19,446,296
Shares issued pursuant to Equity Line (in shares)					647,504
Shares issued pursuant to Equity Line					$ 6,475				669,115					675,590
Share issuance to consultant and other (in shares)					174,954
Share issuance to consultant and other					$ 1,750				203,443					205,193
Vesting expense and option repricing (in shares)					57,573
Vesting expense and option repricing					$ 564				703,848					704,412
Net loss										(19,657,174)				(19,657,174)
Shares issued pursuant to agreement with former CEO related to accrued interest (in shares)					100,401
Shares issued pursuant to agreement with former CEO related to accrued interest					$ 1,004				142,569					143,573
Exercise of warrants (in shares)					5,269,059
Exercise of warrants					$ 52,702				4,461,169					4,513,871
Shares issued pursuant to convertible debt (in shares)					1,107,544
Shares issued pursuant to convertible debt					$ 11,075				502,936					514,011
Shares issued pursuant to transition agreement with former CEO (in shares)					400,000
Shares issued pursuant to transition agreement with former CEO					$ 4,000				(4,000)
Balance (in shares) at Dec. 31, 2021	79,246				65,614,597
Balance at Dec. 31, 2021	$ 792				$ 656,146				167,649,028	(128,040,282)				40,265,684
Issuance of shares and warrants (in shares)					12,000,000								15,520,911
Issuance of shares and warrants					$ 120,000				6,387,050					6,507,050
Shares issued pursuant to Equity Line (in shares)					315,000
Shares issued pursuant to Equity Line					$ 3,150				232,859					236,009
Share issuance to consultant and other (in shares)					596,670
Share issuance to consultant and other					$ 5,967				350,158					356,125
Vesting expense and option repricing (in shares)					236,434
Vesting expense and option repricing					$ 2,364				136,294					138,658
Net loss										(25,737,634)				(25,737,634)
Balance (in shares) at Dec. 31, 2022	79,246				78,762,701
Balance at Dec. 31, 2022	$ 792				$ 787,627				$ 174,755,389	$ (153,777,916)				$ 21,765,892