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Note 7 - Income Taxes (Details Textual) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Income Tax Expense (Benefit), Total $ 0 $ (661,658)
Valuation Allowance Percentage   100.00%
Unrecognized Tax Benefits, Ending Balance 0  
Domestic Tax Authority [Member]    
Operating Loss Carryforwards 316,548,085 $ 308,990,822
Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration 254,897,407 259,490,005
Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration 60,829,929 49,500,817
Operating Loss Carryforwards, Valuation Allowance 66,733,005 62,034,750
State and Local Jurisdiction [Member]    
Operating Loss Carryforwards 232,097,127 227,277,399
Operating Loss Carryforwards, Valuation Allowance $ 14,190,055 $ 23,145,374